The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth lua mods
Everything filed under lua by its own author, ordered by how much it is used.
1,894 lua mods, most downloaded first · newest update 30 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
- Wii Sports Crowd for Chaos Cardby BarneyThis mod adds the crowd from Wii Sports whenever you throw chaos card, and they're all hoping you make a clean shot on that boss you've been saving it for. The crowd will either cheer for when chaos card hits, or express disappointment when it lands on the ground, or hits a wall. This is my first...4.3k downloadsupdated 4 y ago
- Curse of the Fullclearby (SHG)TLgamingThis is my first lua mod. The name says it all. It is the Curse of the Fullclear. You have to Fullclear the floor before you can leave. As reward you can enter every room for free and you have to. We need to go deeper is the only workaround. If you experience any bugs please let me know. Have fun...4.3k downloadsupdated 3 y ago
- [REUPLOAD] Nioffe's Backgrounds and Doorsby 76561198408359456So yeah if anyone isnt in the loop Nioffe the original mod creator deleted his account and everything on it goes *poof*. I figured this stuff is still all very useful to some ppl and stuff so here's the mod reuploaded which includes both his backgrounds and doors. A real shame you had to go Nioff...4.3k downloadsupdated 4 y ago
- More Jingles! (OUTDATED)by SoundbinPlease download More Jingles! Repentogon instead4.3k downloadsupdated 2 y ago
- [REP] Incubus Unnerfby MiyukkiWith this mod Incubus again gives player's damage instead of 75%, same as before Repentance You can get this modification in my Repentane Unnerf Pack too4.3k downloadsupdated 5 y ago
- Mines Rewardby KojimkjDo you find Mines/Ashpit too risky for too little reward? You can now add slightly more reward to those floors! Changes While in Mines/Ashpit, special rock types have an increased chance of replacing regular rocks Additionally, you may now encounter a gold version of the Hardy enemy in Mines, whi...4.3k downloadsupdated 10 mo ago
- The Binding Of Cat Nuoby 76561198431463778Catnuo is a game steamer in bilibili, and you can follow her with the link Mod Description: 1.Two playable Characters Catnuo and Tainted Catnuo Catnuo: (1)start with D6 and 3 bombs (2)Damage Rate = 1.05, Luck = 1 (3)BirthRight Effect: Angel room opening rate increased by 30% Defeating the angel i...4.3k downloadsupdated 3 y ago
- Caves n' Creatures!by Mr. SeemsGoodNOTICE This mod is a little unorthodox in the sense that it's very easy and prone to getting you stuck inside the minigame, one way or another. We also aren't the best coders. Should you ever find yourself in this situation, you should be able to exit and continue your run, in which you'll be sen...4.3k downloadsupdated 3 y ago
- [REP] 20/20 Unnerfby MiyukkiRemoves 0.75 damage multiiplier from 20/20, with this mod it works again like before Repentace You can get this modification in my Repentane Unnerf Pack too4.3k downloadsupdated 5 y ago
- [REP+] Always Restockby 76561199164471930Now there is always a restock machine in the shop This mod ensures that you will always find a restock machine in shops, both in normal mode and in Greed Mode. The restock machine is automatically generated in all shops and adapts by adjusting its position when you play as the Tainted Keeper.4.3k downloadsupdated 9 mo ago
- Random Remaining Completion (Updated!)by Hex: Consume SoyREQUIRES REPENTOGON MOD CONFIG MENU IS RECOMMENDED Updated! Now works with modded characters, both classic and tainted. Not functional with certain mods (e.g. Epiphany), but will not break anything. Currently on save file 2, I’m plagued by trying to decide who to play, as the vanilla random selec...4.3k downloadsupdated 2 mo ago
- Glenn Quagmire Roundy Modby 76561199058554542Hey guys, I made a visual mod of Glenn Quagmire for the Roundy enemy. I hope you like it.4.3k downloadsupdated 14 mo ago
- He's a Phantom [SFX]by machasinsThis mod simply plays a part of the Danny Phantom Theme, "He's a Phantom", whenever Isaac becomes a ghost in Downpour/Dross. Issues? Report it here or in the comments of this mod. Can be configured with Mod Config Menu to adjust how loud the sound is. Thanks to Lazy Mattman for inspiration. I use...4.2k downloadsupdated 16 mo ago
- Cinnamoroll over shopkeepersby 76561199275878382shopkeeper is now replaced with cinnamoroll!! Real man loves sanrio.4.2k downloadsupdated 20 mo ago
- Friend In A Crate (29 familiars in one + 2 challenges!)by 76561198876704734funnyman modding enterprises eagerly presents their newest venture: Friend In A Crate! Friend In A Crate is a familiar item found in shops, crane games and greed mode shops, which spawns a new familiar every room, choosing from a pool of 29 different familiars! All of them are preexisting special...4.2k downloadsupdated 4 y ago
- Oxygen Not Includedby Aks ♐Combining the worlds of The binding of Isaac and Oxygen not included, This mod introduces a new character, the Duplicant, and other nifty items coming from the oxygen not included universe! Current features~ ~~~~~~~~~~~~~~~ New character: Duplicant Damage: -1 Speed: -0.3 HP: 3 ~~~~~~~~~~~~~~~ New...4.2k downloadsupdated 10 y ago
- MajorasMaskModby GiurassicEver wanted to feel protected ? Ever wanted to feel powerful ? Well now you can ! The ALL NEW Majoras Mask will give you everything you need (if all you need is a +5 damage up and 2 black hearts) Soon to come : Different tears ANIMATIONS MORE items Suggestions are welcomed :D4.2k downloadsupdated 10 y ago
- Start with Knife piece 1by BarjuhStart each run with Knife piece 1 Collection with all my Start with mods :4.2k downloadsupdated 3 y ago
- Transdimensional Babyby 76561198330371330MODDING OF ISAAC VERSION A new enemy is approaching the basement... and they come from a different dimension? Transdimensional babies are a brand new and quite rare enemy coming to all stages of the game to spice up your gameplay even more. Featuring: A new enemy. A new room for each floor, and a...4.2k downloadsupdated 3 y ago
- No Stickies on Tainted Keeperby DoggersI think Tainted Keeper players can relate to this scenario. You are playing Greedier mode. You are left with a single coin heart, because game has decided to give you a bullet hell. You have killed a little poor Gaper which has dropped a Nickel! Time to pick it up. Wait, what's that? It's glued t...4.2k downloadsupdated 3 y ago
- ADHDby The Australian King Of ArrowsA simple little mod pack that gives you a new item and a new pill: Items: * ADHD - Get a massive speed boost, however you get a constant slight shaking to your character. Can't stop, won't stop. Pills: Ritalin - Give's you a small speed boost. However if you have picked up ADHD, then this pill gi...4.2k downloadsupdated 10 y ago
- Jujutsu Kaisen Soundtrack for (Soundtrack Menu)by JohnyyJujutsu Kaisen Season 1 And 2 Soundtrack For Isaac. TRACK LIST -------------- Floor Music -------------- Basement = Put It In This Fist Cellar = An Unfair Reality Granted To All Equally Burning Basement = Expectation Caves = Strong And Inteligent Allies Catacombs = To Select How To Die Flooded Ca...4.2k downloadsupdated 2 y ago
- Beth The Demon: Remasteredby Anya MouthwashingAn Original character, Beth! She's a Brimstone demon who loves matchmaking! Using her charming MATCHMAKING BEAM, she can obliterate enemies, make them fall in love, or both! (No relation to the Repentance character, Bethany.) Beth has been REMASTERED, now featuring beautiful art and sprites by So...4.2k downloadsupdated 5 y ago
- Discord Advance Rich Presenceby nikosBetter rich presence status. Important Currently there is only windows support. For this mod to work you need to enable the debug flag (instructions below). This is needed because in order to communicate with discord I need to write to a special file and to do that I need the debug flag on. The f...4.2k downloadsupdated 6 y ago
- Decent Startby 76561199481423011There will spawn 1 coin 1 bomb 1 key 1 wooden chest in the starting room. 初始房间会生成1硬币,1炸弹,1钥匙和1木箱子。4.2k downloadsupdated 20 mo ago
- Pariku, The Soul Embracerby StrangeOne101This mods adds a new character, Pariku, to the game. The character is based of the streamer, ParikuYumi, but stands as its own character within Isaac. Lore wise, Pariku is the daughter of Lilith, and has deep control over souls. The more souls she controls, the stronger she becomes. In game, the...4.2k downloadsupdated 3 y ago
- Risk of Rain Soundtrackby arcana packrisk of isaac REQUIRES SOUNDTRACK MENU MOD Music from Risk of Rain + Risk of Rain 2 + DLC OST by Chris Christodoulou Track List Basement - Disdrometer Cellar - Terra Pluviam Burning Basement - Moisture Deficit Caves - Evapotranspiration Catacombs - Cyclogenesis Flooded Caves - Into the Doldrums D...4.2k downloadsupdated 4 y ago
- Items Reforged [Afterbirth+]by KaliItems Reforged! This mod aims to rebalance and tweak items that would otherwise be detrimental to a run, while remaining faithful to the vanilla experience. Supports External Item Descriptions! Supports Mod Config Menu! Supports Revelations! Supports Fiend Folio! & More! All changes are configura...4.2k downloadsupdated 6 y ago
- Social Anxietyby Exudias*Passive item *You feel endangered! (You gain damage proportionate to the amount of enemies in the room you are in) This is my first passive item I've added to the game. Awesome people: Lytebringr, Eufuu and CustomPhase See it in action here:4.2k downloadsupdated 10 y ago
- New Delrium Formsby 76561198993684021Have you ever fought Delirium and noticed that there was a missing Delirium sprite for one of the bosses? Delirium Forms+ fixes this by implementing sprites made by me! Delirium Form+ adds 3 new forms for - Bumbino - Reap creep - The Pile This is my first mod ever and first time editing Isaac spr...4.2k downloadsupdated 3 y ago
- Critical Damageby 76561198808901865"Team Decadence Presents." Critical Damage - Created by Harvester, Nihil, ENFOR, MINDS3T and Pupzables(as pfp art contributor)! <Introduction> Simply creates a red vignette and heart monitor effect overlay when on critically low health and on taking damage. This creates a more immersive and tense...4.2k downloadsupdated 4 y ago
- [REPENTOGON+] Scrapped Enemy Altsby 76561198381001296This mod requires REPENTOGON+! The Antibirth Scrapped enemy alts have finally appeared in the basement! This is a remaster of two of my old mods, combining both the base mod and the modded room pack, with new features and improvements. Features: -9 Enemy alts to kill or be killed by. -Toggleable...4.1k downloadsupdated 4 mo ago
- Spray Paintby ☢ Nato Potato ☢This item inspired by Jet Set Radio allows you to 'tag' the walls of certain rooms with graffiti, each completed graffiti tag in the room boosts your DPS. When you have the item most rooms will have spots against the walls where you can paint, by interacting with these spots (SHIFT/CTRL/swap) you...4.1k downloadsupdated 2 y ago
- Lil' Blastocystby XalumFollowing my pattern of boss-based familiars I introduce Lil' Blastocyst. This orbital will slowly break down as it's hit, disappearing over time. Breaking down into a maximum of four separate orbitals. At the start of each new floor the orbitals will regenerate into the largest size and can be b...4.1k downloadsupdated 9 y ago
- Syringes! A New Consumable [Afterbirth+ Only]by AgentCuccoA brand new type of consumable! - Syringes behave similar to pills, they give temporary buffs or debuffs to the players, and they are undiscovered until used for the first time. - At the beginning of a run, a pool of 13 random syringes is determined for the rest of the run. - Syringes have a 33%...4.1k downloadsupdated 6 y ago
- Occasionally you will hear the Stalker Screamby GuilhermeI don't know why I wanted to create it, but I saw that no one created a mod like this, so let's be the first one. you will hear the scream of the Stalker from Half-Life 2 occasionally, the timing between each scream will be random, you never know, can be some seconds, or can some minutes, or some...4.1k downloadsupdated 3 y ago
- Dogma Clickerby Phno 🐙"Having trouble with your TV? Just switch the bloody channel. Easy as that :v" It should be completely normal and logical that you can defeat an enemy, which comes out of the tv, instantly if you just turn off the tv. Right? Right. So, now this is possible with the clicker. The clicker remains it...4.1k downloadsupdated 3 y ago
- JUDGMENTby 76561198452562022Replace the Bethany sprite with Judgment from helltaker4.1k downloadsupdated 23 mo ago
- Keep the Boomby Sora-MMKHere we go with my third and first Hard Challenge: Keep the Boom! (And don't let you get hit!) ►Character: ➥Keeper ►Start Items: ➥Wooden Nickel ➥IPECAC ➥Soy Milk ➥Sad Bombs ➥Greed's Gullet ➥A Dollar ➥Curse of the tower ➥Dr. Fetus ➥Car Battery ►Goal: ➥Mom ►Stats: ➥Reduced start-damage to 8.10 ►Mod...4.1k downloadsupdated 10 y ago
- Box Cutterby nickBOX CUTTER Let your soul escape Type: Active Cooldown: None Effect: Take one red heart damage and spawn a half soul heart. Pools: Shop, Secret, Curse An activated item, Box Cutter has no cooldown. Instead, it uses your life as a resource. Every time you activate Box Cutter, it will deal you a red...4.1k downloadsupdated 10 y ago
- Red Keyby 闼昂Red Key on start.4.1k downloadsupdated 3 y ago
- A Dance of Fire and Isaac!by PoondaedalinHappy April Fools' Day! I made a rhythm game in Isaac! As per usual, the content of this mod can be accessed by going into the Custom Challenges, and finding the challenge named "PD - A Dance of Fire and Isaac!". The mod includes 5 tracks (which may increase in the future, but I make no promises)...4.1k downloadsupdated 19 mo ago
- Dr. House Over PHDby 76561199231191134This mod changes the sprite for the items PHD - Dr. House False PHD - Evil Dr. House note: if you dont like Evil Dr. House just deleting him from the mods files via picture should remove him4.1k downloadsupdated 16 mo ago
- Pikachu Characterby Arcane(This is my first character mod pls dont kill me) This mod adds a new playable character Pikachu he starts with Jacob's Ladder has 2 dmg high speed and high shot speed4.1k downloadsupdated 8 y ago
- Crap-B-Gone!by 76561198391988105Guarantees that the item from the first treasure room will have a quality of at least 2. Works in Normal, Hard, Greed and Greedier mode. Alternate version for quality of at least 3: It's only meant to help do not quite as many R presses. It doesn't change, drain or affect in any way the pools or...4.1k downloadsupdated 5 y ago
- Sad Heartby EstrogenGirlSad Heart "Be hearty" - For every red heart container you have, empty or full, you get a 0.25 damage up. Coded by AstroPenguin642. Sprite by CatnipOverdose. Costume and Thumbnail by TRPG.4.1k downloadsupdated 9 y ago
- The Darksign [REPENTOGON]by ChrisSor54REQUIRES REPENTOGON TO FUNCTION! The Darksign has appeared in the basement... This item grants you the curse of undeath, but at a heavy price. Upon death, Isaac will resurrect at the starting room of his current floor as a Soul, a fragile spirit who gains the powers of flight and spectral tears,...4.1k downloadsupdated 2 y ago
- Start with There's optionsby BarjuhStart each run with There's options Collection with all my Start with mods :4.1k downloadsupdated 3 y ago
1.9k lua mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

