The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth enemies mods
Everything filed under enemies by its own author, ordered by how much it is used.
359 enemies mods, most downloaded first · newest update 26 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
359 enemies mods
- Boss Rush Wave Counter [Rep | AB+]by Kanye EastTHANK YOU FOR USING MY MOD! :) Originally, this mod was a small weekend project I made when I was 16 on a MacBook I shared with my family, I never expected it to get as much traction as it did lol. The awesome ppl in this community helped me test it to make sure that it worked with REP at the tim...1.4M downloadsupdated 4 y ago
- Watch out, laser!by TidloasSkill Issues is the successor to this mod made for Rep+. It will not be updated. If you want updates or just a working mod, check here: Watch out, laser! Adds a visual effect to (almost) all Brimstone attacks to increase their visibility! I highly recommend installing Mod Config Menu Pure to be a...702.7k downloadsupdated 4 y ago
- Da Rules - A Sandbox Menu Thingy [Rep/Rep+/AB+]by JSGDa Rules is a sandbox-style menu that allows you to mess around with almost anything in the game, from monsters to visual effects. Sure, you can do "Every item is"...BUT you can also replace, resize, push, rotate, at tach, path, animate, change costumes and a LOT more than that. Theres extra effo...483.7k downloadsupdated 4 mo ago
- [REP- ONLY] Fiend Folio: Reheated - 500 New Monsters!by ErflyFOREWORD This version of the MOD is for Repentance only. However, there is an updated REPENTANCE+ VERSION linked here! Why settle for less items, less monsters, and less characters? More can be found in Fiend Folio: RELOADED! Check it out! Fiend Folio MOD is back in town baby! The original MOD ha...411.2k downloadsupdated 3 mo ago
- Coming Down! [Rework]by TidloasSkill Issues is the successor to this mod made for Rep+. It will not be updated. If you want updates or just a working mod, check here: Coming Down! adds high-visibility visual tells to all stomp/jump attacks Basically, this mod aims to reduce the frustration against hard to see attacks, coming f...358.4k downloadsupdated 4 y ago
- Angels Drop Itemsby SokyWere you ever annoyed that after getting both key pieces fighting both Uriel and Gabriel was entirely pointless? Have you never gotten lucky to get the Filigree Feather while going for the Angel Rooms? Wanted to reroll the Key Pieces with D6, but couldn't get anymore of them? If you said yes for...326.4k downloadsupdated 5 y ago
- Neko Stoney Spriteby LeeYou've read it. It's neko stoney sprite made by me from NY_Sagittarius video.285.6k downloadsupdated 6 y ago
- Neko Hush Respriteby SkiiveIs Hush too scary? Then make him cute! (sort of) This mod edits all of hush's sprites and animations and adds cute cat-ears, whiskers, and mouth! It works with both AFTERBIRTH & REPENTANCE Files edited are the following: \resources\gfx\bosses\afterbirth\boss_078_bluebaby_hush.png \resources\gfx\b...255.0k downloadsupdated 6 y ago
- Revelations (AB+ only)by SentinelWARNING This mod REQUIRES the StageAPI and Mod Compatibility Hack mods to function. Get them here and here. IF YOU HAVE STRANGE ERRORS AFTER INSTALLING THE MOD, TRY DELETING THE MOD'S FOLDER AND RESTARTING THE GAME (see below) Announcements The Chapter 3 character, Bertran, got released as a stan...216.0k downloadsupdated 5 y ago
- Watch out, Explosion!by TidloasSkill Issues is the successor to this mod made for Rep+. It will not be updated. If you want updates or just a working mod, check here: Watch out, explosion! Adds a visual effect to (almost) all sources of explosion to increase their visibility! I highly recommend installing Mod Config Menu Pure...160.6k downloadsupdated 4 y ago
- Alphabirth Pack 2: All That Is Unholyby FacemanFoothandThe Binding of Isaac Alphabirth: All That Is Unholy is the second official modpack from Team Alpha! This pack adds: > 29 new items! > 11 enemy variants! > 2 new transformations! > 1 new character! (Be weary of Black Hearts!) > 4 new runes! > and 4 new challenges that unlock content upon completio...142.9k downloadsupdated 9 y ago
- Alphabirth Pack 1: Mom's Closetby DeadInfinityThe Binding of Isaac Alphabirth: Mom's Closet is the first of many packs to be developed by TeamAlpha! Download the complete Alphabirth collection here: This one in particular adds: > 31 new items! (including 3 unlockables) > 2 new trinkets! > 1 enemy variant! > 1 new transformation! > 1 new pick...142.4k downloadsupdated 9 y ago
- Revelations Ch. 2 [Rep]by FilloaxThis is the Repentance version of the mod, for the Afterbith+ version see here. This mod REQUIRES the StageAPI mod to function, and the REPENTOGON mod is heavily recommended for performance, features and to avoid download failures, and will be required in Chapter 3. IF YOU HAVE STRANGE ERRORS AFT...134.7k downloadsupdated 2 y ago
- [RGON] Repentance Plus!by Mr. SeemsGoodThis mod requires REPENTOGON to operate, for optimization and modding convenience purposes. More Unlocks to Spice Up Your Game! Repentance Plus is a mod that adds: 59 new items; 23 new trinkets; 41 new cards; 6 new pills; 17 new heart pickups; 4 new chest variants; and a bit more? into the game!...129.3k downloadsupdated 9 mo ago
- Greed Mode Improved Repentanceby SkollieAfter months of development hell, it is finally here! The Repentance update to Greed Mode Improved! As the title suggests, this mod improves greed / greedier to be a lot more fun, balanced, and adds a lot more variety to both modes. This mod does make greed / greedier easier, but that wasn't my g...117.6k downloadsupdated 4 y ago
- Neko Turretsby HibikiChanges a few of the Grimace sprites to be nekos what else would it do? Based off the Neko Stoney Mod, and NY_Sagittarius video. Not all of the turrets are supported in this100.9k downloadsupdated 5 y ago
- Deliveranceby BaicherraNo, this mod doesn’t add any new floors, huge bosses(?) or anything like that. We’ve put some cute monsters and items which we'd like to see in the game! In general, Deliverance adds: 44 new items! 8 trinkets, 4 cards, new heart and a new pill! 30+ new enemies! 900+ new rooms! Secrets! Mod Suppor...99.9k downloadsupdated 11 mo ago
- Alphabirth Pack 3: The End Timesby FacemanFoothandThe Binding of Isaac Alphabirth: The End Times is the third official modpack from Team Alpha! This pack adds: > 20 new items! > 7 new enemies! > 2 new pickups! > and 1 new challenge that unlock content upon completion! This mod requires AlphaAPI to play: We highly recommend you play with all of o...99.7k downloadsupdated 9 y ago
- Godmode Unleashed [AB+]by MINDS3TFor the Repentance version, GO HERE! Current features: 29 Items! 7 Bosses! 7 New Floors! 2 New Pickups 1 New Pill! 20 New Enemies! 5 New Characters! 1 New Challenge! Revamped special items system! Wait, what did you do to special items?? Don't worry, I made quite a few more items categorized as s...95.3k downloadsupdated 2 y ago
- DarkShesauby BaicherraART PREVIEW MADE BY KinoZukna! PLEASE FOLLOW Don't you like the usual Dark Esau? Well, this mod changes Dark Esau Gender, turning your gameplay into an unforgettable fun(or hellish torment). Included: -New sprites; -New animations; -boss/stage portrait; -Death screen portrait;93.6k downloadsupdated 5 y ago
- today i will kaboomby Xtrikethis mod replaces the giga bombs with the "today i will/clueless" meme90.7k downloadsupdated 3 y ago
- JoJo's Kira and DIOby [TBG] Alvys14BlackWith this mod you can play as DIO from Jojo's Bizarre Adventure: Stardust Crusaders! DIO will start throwing knives and with the item THE WORLD. This item will stop time for 3s as DIO was able at the start and will summon his stand for 10s. DIO as vampire has also recovery life powers when he kil...87.0k downloadsupdated 6 y ago
- Better Vomit Grimace Spriteby 76561199017419812Vomit Grimace is no longer a stone grimace covered with green paint. This mode makes the vomit grimace look unique and better.86.9k downloadsupdated 5 y ago
- Instant Restartby 76561198335323471Reset on R is a small and lightweight mod that lets you instantly restart your run by pressing the R key, without going back to the main menu. 🔁 Perfect for speedrunners, item rerolls, or quickly resetting for a better run. 🛠 Compatibility: ✅ Compatible with The Binding of Isaac: Repentance ✅ Upd...83.3k downloadsupdated 18 mo ago
- Proper Mausoleum Grudgesby 76561198874005341Changes Grudges eye color to purple to match the Mausoleum astetic Note: color change only applies to the base variant of the grudge, Gehenna variant is left untouched81.4k downloadsupdated 4 y ago
- Retribution: 190 Itemsby XalumWarning The Repentance+ DLC broke the modding api in a whole load of different ways, there is no guarentee of compatibility between this mod and the Repentance+ DLC until these issues have been fixed. If you play with Retribution while using Repentance+ you do so at your own risk and should expec...80.4k downloadsupdated 3 y ago
- THE FUTUREby 76561198986837426You reek of sadness! Please poke your head into THE FUTURE! Enter the Future, an optional challenge floor inspired by Edmund's work that has a chance to show up each run. A ruined and soggy world awaits you, filled with rot and temporal invaders. FEATURES a NEW FLOOR containing....... 30+ cancero...78.6k downloadsupdated 3 y ago
- Improved & Reworked Foesby PixelPlzReworked Foes makes many of the game's enemies and bosses more interesting, balanced or harder by changing or even completely reworking them. Features: Over 30 changed bosses, including complete reworks! Over 50 changed monsters, with many balance changes and unique reworks! Toggleable quality of...75.4k downloadsupdated 2 mo ago
- Off-screen Indicatorsby PixelPlzHave you ever just sat around blindly shooting at Delirium while he's off-screen somewhere? Have you ever lost track of your Ludovico Technique tear in a big room? Then this mod is for you! Features: Indicators for the following things when they're off-screen: - Bosses - Enemies - Ludovicho Techn...71.1k downloadsupdated 3 y ago
- Bold Brim Beamsby SprSnpr_Be BOLD with your Brimstone! I've always found the Brimstone beam to look slightly... flat. This mod darkens the edges of Brimstone's beam in order to give it a more defined look. This mod affects every version of Brimstone in the game- save for The Beast and Cage Vis' Brimstone.66.4k downloadsupdated 3 y ago
- (AB+ ONLY) Fiend Folio - 250 New Monsters! ...and more?by ErflyFOREWORD: This version of the MOD is for Afterbirth+ ONLY However, there is a REPENTANCE VERSION linked here! Why settle for 250 new monsters when you could have 500 new monsters, 140 new items and so much more! Check it out! It's finally time to dive into Fiend Folio! From those who worked on Re...66.4k downloadsupdated 4 y ago
- +18 XapDM0:Dby 76561198375019062( ͡°👅 ͡°) NEW GLOBAL MOD FOR ISAAC64.8k downloadsupdated 7 y ago
- Totally Unnecessary But Nonetheless Epic Giga Bomb Synergiesby 76561198876704734Funnyman Modding Enterprises is BACK! With another BANGER! (no pun intended) (they also do commissions so hit them up lol) This mod adds 12 new synergies between Giga Bombs and bomb related items. The list is as follows (and yes, they do stack.): Bob's Curse Fills the room with toxic gas that dea...62.8k downloadsupdated 22 mo ago
- The Binding Of Pokemon + (NO LONGER SUPPORTED)by TechTHIS VERSION OF THE MOD IS NO LONGER SUPPORTED, THANK YOU FOR HAVING DOWNLOADED THIS AMAZING MOD AND PLAYED IT!!! If you want to play the sequel, here it is, The Binding Of Pokemon + Legends Expansion (WIP) It'll be worked on by the amazing Nalejandro3 ! I'll still help on things too ! Mod by Tho...60.7k downloadsupdated 6 y ago
- Ambush Spawn Indicators [REP]by PixelPlzThis mod adds cool indicators for wave based things, such as Greed Mode! The size of the indicators match their corresponding enemy's size as well! Note: This mod requires REPENTOGON to function! Features: Indicators for the following things when they're about to spawn: - Greed Mode waves - Chall...60.2k downloadsupdated 18 mo ago
- Greedier Bosses Deluxeby slapjakThis mod adds greed-themed reskins for bosses that appear in Greed Mode! Does not include the Horsemen, Sins, and Promo bosses (Steven, Gish, etc). This mod only applies the skins to Greed Mode by default, but they can be applied universally through the use of the Mod Config Menu. Individual boss...59.5k downloadsupdated 4 y ago
- [Rep] Sacred Dreams Act Iby 76561198354826432Prepare to delve into Isaac's dreams in this unofficial (duh) prequel to the original game: A new Character! Unlockable achievements! 20+ items! New trinkets! New pickups! New music! And more... The Dream Guard starts with a pocket active item: Sand Pouch Use it to apply a new status effect somno...57.9k downloadsupdated 23 mo ago
- Arena Mode (AB+ Only)by SentinelThis Mod adds a whole new Mode: In the first room: Choose your items - You must pick 1 out of 5 items - You will get 10 items - After picking 10 items you will go to the arena - there are 3 new items and 1 new enemy In the arena: Fight of Monsters - There are 20 waves of Monsters - The waves will...57.8k downloadsupdated 10 y ago
- [AB+] DDLC Isaac Modby CrashpunkOUTDATED! DOES NOT WORK WITH REPENTANCE! DOWNLOAD THE NEW VERSION! >>>Doki Doki Repentance<<< Featuring new items, Tainted Dokis, Birthrights, many bug fixes and reworks! --------------------------------------------------------------------------------------- Doki Doki Literature Club! Isaac Mod (...56.2k downloadsupdated 5 y ago
- Potato for scaleby SinstharYou know how much damage you do... you know what your fire rate is... But do you know how much damage per second you do to a simple target ?! Hell no ! So... Here comes the POTATO ! The first DPS Meter for Binding of Isaac ! You'll find it in the first room in each floor (or in the "silver" Treas...55.8k downloadsupdated 5 y ago
- Lump Fixby unendingEmpathyLumps are a pain in the butt, and while there is a mod to "fix" them by removing them from the game entirely, I wanted a way to fix them without doing that. And this is the result! This mod gives the Lumps an animation for when they do their "hide and shoot" thing that leaves them open for much l...55.7k downloadsupdated 5 y ago
- 18+ MODby 76561199059088718This is a mod that changes the game's sprites to fit the 18+ theme. It affects the appearance of enemies, bosses, characters, items, and many other small details. This mod is a new version of an old project, invented on April 16, 2022, on which I worked. For a long time, I did not touch this mod...54.2k downloadsupdated 15 mo ago
- IPECAC Community Modby pedroff_1(If you're looking for the Afterbirth+ Version, click here!) (If you have the Transformations+ API and/or Mod Compatibility Hack, those are no longer required nor supported) Welcome to the IPECAC Community Mod! The IPECAC Community Mod is a mod focused around the community, and as such, a large p...51.0k downloadsupdated 3 y ago
- DarkShesau Compatible With Birthrightby 76561199074427380THE CODE AND SPRITES ARE FROM THE ORIGINAL SHESAU MOD BY Baicherra PLEASE CHECK OUT THE ORIGINAL MOD: This mod just changes the sprites from the Shadow of Esau when you pick up Birthright To change the original Dark Esau you need to download the original mod48.9k downloadsupdated 4 y ago
- Last Judgementby GuwahavelThis is 1 portion of the mod, which only has the new content. The resprites and vanilla tweaks are in here. Last Judgement is a major content mod which aims to restore thoughts, ideas, and concepts that were proposed during the development of the official Binding of Isaac: Repentance DLC. Ideas w...48.4k downloadsupdated 1 mo ago
- [AB+] Retribution - 109+ Itemsby XalumATTENTION RETRIBUTION HAS BEEN UPDATED FOR REPENTANCE GET IT HERE: !!! This mod will not function correctly without Mod Compatibility Hack !!! Retribution adds 109 147 brand new items to the Binding of Isaac - ranging from a feeble axolotl friend to a cursed pumpkin mask. Play as Icarus, who star...46.2k downloadsupdated 6 y ago
- Fall from Grace (Boiler and Grotto)by GuwahavelDo you have what it takes to stay afloat in the Boiler and the Grotto? Fall from Grace is a floor expansion mod which adds alternative floors which can appear when traveling through the floors added in the Repentance DLC (the Mother path). Boiler is a hot and steamy alternative to the Downpour! G...45.9k downloadsupdated 2 y ago
- The Binding of Isaac: The Devil's Harvestby TeamPROBIRTHIntroducing The Binding of Isaac: The Devil's Harvest MOD. Made by a team of elite The Binding of Isaac: Afterbirth+ modders named Team Probirth, this total conversion expansion mod is guaranteed to shake up the now stale meta of Isaac franchise forever by introducing wacky new groundbreaking con...43.4k downloadsupdated 10 y ago
359 enemies mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

