The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth tweaks mods
Everything filed under tweaks by its own author, ordered by how much it is used.
1,627 tweaks mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.6k tweaks mods
- Esau starts with There's Options!by kittenchillyEsau now starts with Theres Options! Now both characters can get an boss room item for a smoother J&E experience.14.5k downloadsupdated 3 y ago
- Bank Shot Respriteby MaddogsDue to popular demand and personal delight, I've decided to re-sprite the Pop! item and its tears! Each Pop! tear is now one of 15 randomly chosen pool balls, to better fit the sound effects, and bring it closer to the Bank Shot mod we all know and love! Thank you to Scayze and Ashkait for the or...14.5k downloadsupdated 9 y ago
- Samotna Skała 2000by domek z gówna[19.11.21] - Rock Bottom is now Very Sad Remigiusz :( [14.09.21] - The Small Rock is now The Small Mishor [11.08.21] - All tinted rocks has become RockAlone2k Joke mod for my friend Marooda. Switching tinted rocks with face of the most famous polish youtuber.14.5k downloadsupdated 5 y ago
- Start with 4 quality itemby 76561198958671677The first item you see in an item room have a quality of 4. (powerful) This mod will save your R key :014.5k downloadsupdated 12 mo ago
- Cube Baby is Now Fumo Cirnoby 76561198813288416Do you like fumos??? Do you like Cirno??? Do you like Toohou??? Touhou No?? Well have this high-quality crappost of a mod, Fumo Cirno! She replaces Cube Baby and she speens! That's right! She spins! Cube Baby's collectible and sprites have been replaced by the strongest girl in the universe! Down...14.3k downloadsupdated 5 y ago
- Jacob and Esau Overhaulby DeadInfinityThis mod makes Jacob and Esau enjoyable to play. Features Control Jacob and Esau independently, simultaneously! Use movement keys to move Jacob, and firing keys to move Esau! Watch as Jacob and Esau fire automatically at your enemies! Manually command their targeting with the drop input, or the s...14.3k downloadsupdated 5 y ago
- Better Godhead Auraby SprSnpr_Better late than never! This mod changes the Godhead tear aura slightly less... obstructive Also check out my Better Monstrance Aura mod!14.3k downloadsupdated 5 y ago
- Neco Arc instead of Guppyby 76561198799951412This mod is supposed to be used with vhotart’s "turn into neco arc" mod! (click) With this mod, you will finally be able to make your Neco-Arc obsessed Isaac experience more immersive. Install this mod and let your life be overtaken by the funny cat. I and vhotart apparently had the same idea at...14.3k downloadsupdated 3 y ago
- Iryo's fair Treasure Room Startby 76561199146259149Compatible with Repentance+! I was looking for a mod doing exactly this and only this: 100% Treasure Room start without changing any Items, Qualities or Odds, so i decided to just do it myself! This is how it works: When you start a new run, the game reseeds a bunch of times within less than a se...14.2k downloadsupdated 3 mo ago
- Gapery Gapers [DISCONTINUED]by 76561198417302118This mod was originaly just my spriting practice, but i decided to turn this into an actual mod, so here you go! This mod changes the appearance of a bunch Gaper enemies to make them look a bit cleaner and overall better. Enemies re-sprited: -Horf -Dople -Flaming Gaper -Cyclopia -Gaper -Downpour...14.2k downloadsupdated 5 y ago
- Clear item descriptions (Outdated)by CaptainNOTE: THIS MOD IS OUT OF DATE. I don't plan on buying repentance but feel free to use this mod as a basis for your own descriptions mod. Changes all items and trinkets to clearly state their effects! No more vague nonsense! Note that it doesn't tell you exactly how much DMG or range you might gai...14.2k downloadsupdated 9 y ago
- Chain Dragby ☢ Nato Potato ☢With this mod the soul can drag the forgotten by pulling on the chain, if a door or pickup is out of your reach you don't have to switch to forgotten, move 2 feet and then switch back just to get to it, you are no longer forced to switch to the forgotten when you don't want to and shouldn't need...14.1k downloadsupdated 20 mo ago
- Pog Lumpsby 76561198985263588I got Bored at 2am and made this, im sorry14.1k downloadsupdated 5 y ago
- HardMode Major Boss Patterns(AB+ only)by DotThis is AB+ version of the mod, Repentance+ version is here: This mod adds new patterns and phases of major bosses in hard mode. Also involves some pattern enhancements, shields and resprites. This mod is still in development, bosses with new patterns or phases implemented are as follows. -The La...14.1k downloadsupdated 6 mo ago
- BetterRocketBombby 76561199092966895中文版介绍放在后面哦。 The ANNOYING 'Rocket in a Jar' is finally improved! Just a simple tweak brings much better game experience. Once you subscribe to this mod, the launch of the rocket will be no longer related to Isaac's body motion! Therefore, you can kick the normal bombs to ANY PLACE as you used to d...14.1k downloadsupdated 5 y ago
- Lazy Mattman Screams For Good Itemsby ruberWOOOOW A mod that adds Lazy Mattman's scream for 4 quality items. There are 10 variations of the shout in the mod (which are played RANDOMLY, realistically). Enjoy and good luck! P.S. Special thanks to D1m7asis for help with the code14.1k downloadsupdated 3 y ago
- The Typing of Isaac!by PoondaedalinI hope you can type fast, because the enemies can run faster! St. Dvorak's Tablet can be found in the Treasure Room pool, and its effect causes enemies to display text below their sprites. Typing in the word displayed deals heavy damage to the enemy proportional to Isaac's damage and the length o...14.1k downloadsupdated 2 mo ago
- !FRAUD's Poratrait Respruce (With ACS and Tainted Names)by ChandlerFRAUD's Portrait Resprites are my absolute favorites, and its not close. But having the alternate tainted names on the character select is super cool. There exists a mod to merge the two, but that one didnt include the ACS, and I couldn't find one that did. So I made one myself. This mod includes...14.0k downloadsupdated 3 y ago
- [REP(+)] TOO MANY REMINDERSby CxRedixDo you have gold fish memory like I do? Have you always went to the wrong alternative floor and hated yourself for it? Have you got the Polaroid but went down to Sheol instead? (or vice versa) FEAR NOT. Too many reminders will overflow you with REMINDERS! Notice: I decided to take a break from Is...14.0k downloadsupdated 9 mo ago
- The Beast Replaced by Evil Fucking Catby 76561198995154797This vile beast has taken over the underworld! Stop her before she unleashes chaos on the basement! This mod replaces the beast with my cat (Tess) Made as a joke for some friends of mine13.9k downloadsupdated 2 y ago
- Choose Cycling Items - No More Glitched Crown Misses [RGON]by JasonwqqRequires Repentogon Allows you to choose between cycled items after picking it up via LEFT and RIGHT firing keys. Press UP firing key will confirm the selection. Press DOWN firing key will drop the item on the ground. Useful for items such as Glitched Crown or Isaac's Birthright + Binge Eater. Wi...13.8k downloadsupdated 1 mo ago
- More Mushrooms! [AB+]by JSJoshBecause you can never have enough mushrooms! This mod adds 10 new passive mushrooms to the treasure, secret, and boss pools, with a few interesting effects to boot! Also makes fun guy a LOT easier to get! Odd Mushroom (Bulbous) Found in the treasure and secret room pools Increases damage and give...13.8k downloadsupdated 8 y ago
- Damage Trackerby 76561198864337504Ever wonder how much damage you take in a typical run? Do you want to see how much intentional damage you take as Tainted Maggie, or how many holy cards you burn as Tainted Lost? Built off the Planetarium Chance mod by Peachee, this mod adds two new stats to your found hub. One tracks the total a...13.8k downloadsupdated 2 mo ago
- Lost Items Pack [NEW WOMB UPDATE]by ENFORLost Items Pack Mod Made by Enfor 41 + new items 26 Passive Items 10 Active Items 5 Trinket NEW EXPANSION AVAILABLE ROBOT REWORK !!! WOMB UPDATE NEW CHARACTER ROBOT NEW ITEMS Pubes Testament Blue Heart Pact of Blood Tears of joy Core NEW COSTUMES, SYNERGIES AND BUGFIXES ---- DIVIDED 1 heart + 3 s...13.8k downloadsupdated 7 y ago
- No More Useless Items: Afterbirth+by Flap_Jack2.0 UPDATE! Added support for The Forgotten! Covers all items up to and including Booster Pack 5! Keeper is now rescued from death if you get Abaddon on an item reroll! Thank you all for your continuing support! -------------------------------------------------------------------------------------...13.7k downloadsupdated 5 y ago
- Fumo Shopkeepersby 76561199102200098Changes your shopkeepers and secret room keepers into Touhou Fumos!! Yes, the hanging ones as well... Fumos will still display if they have nickels in their eyes! The I Am Error keeper has also been changed to Fumo There are a total of 11 different Fumos to see in the shops, secret rooms, etc etc...13.7k downloadsupdated 2 y ago
- It's Going Down Now for Good items (DROP VERSION)by PeridarrenDISTURBING THE PEACE, LOOK INTO MY EYES Wanted a version where it starts at the drop instead? WELL HERE YA GO! The Specialist dance but instead it uses It's Going Down Now from Persona 3 Reload. Full song version If you wish to use it with Reaction Port Pack instead, someone made a mod that adds...13.7k downloadsupdated 20 mo ago
- The SAAC portraitsby 76561199590469868Changes all portraits to the SAAC inspired by the saac title screen mod by zx13.7k downloadsupdated 4 mo ago
- Item Expansion Baseby KyoZM---Base Expansion--- Item: "Demon Heart" Description: "Bleed for me!" Effects: HP+1 DMG+1.5 Item: "Heretic" Description: "Angels Fall!" Effects: DMG+1 Makes Mega Satan path viable with devil precident. Adds Angel statues to devil deal rooms. Item: "Reckoning" Description: "Divine judgement befall...13.6k downloadsupdated 10 y ago
- Fancier Chests!by 76561199017158324i redid all the chests because i didnt really like the vanilla appearance due to simplicity and mod conflict avoidance: a passive item spawning from a chest will make the chest (pedestal form) vanilla again this mod currently supports: - Red Ending Chest in Sheol (more coming soon) enjoy♥13.6k downloadsupdated 2 mo ago
- Shader APIby 『Sora』Modder tool. Adds a fix for shaders which allows multiple mods to have their shaders function at the same time instead of overwriting eachother. To use, simply replace the "return {stuff}" of your shader callback with shaderAPI.Shader('ShaderName",{stuff}), and add an if statement to check for sh...13.6k downloadsupdated 9 y ago
- FLESH PRISON over Moms Heartby 76561198420588728I thought it'd be funny ok. The mod changes the looks and sounds of It lives, as well as Mom's Heart fights. It will probably conflict with other reskins so be aware of that. Credits: FLESH PRISON as well as the music from ULTRAKILL by Arsi 'Hakita' Patala. p.s. Its my first ever mod for isaac so...13.5k downloadsupdated 19 mo ago
- Discord Advance Rich Presence - Continuedby KehtoBetter rich presence status. This mod is based on NikosSiak's work Instructions Right click the game in your library Click "Properties..." Click "SET LAUNCH OPTIONS..." Write "--luadebug" on the input box and click OK (you may want to read the security concerns bellow regarding that) Security Con...13.5k downloadsupdated 3 mo ago
- Improved Spritesby 76561198441604374Mod changes 100+ sprites of items thats pretty much it. I will most likely stop updating this mod, as Isaac has become quite boring for me.13.5k downloadsupdated 23 mo ago
- Quartz Respritesby QZSOME OF THESE ARE INCLUDED IN THE LAST JUDGEMENT MOD: DOWNLOAD THAT, OK? ------------------------------------------------------------------------------------------------- Resprites certain enemies and familiars to be up to par with Repentance's sprite quality, while retaining the vision of the or...13.4k downloadsupdated 5 y ago
- Sorted Heartsby ☢ Nato Potato ☢Very simple. The players health bar is sorted. By default its bone hearts > soul hearts > black hearts, but you can change the order by using the Mod Config Menu. Works with the No Health Cap mod. This is included in POTATO PACK 2.13.4k downloadsupdated 4 y ago
- [RGON]Benighted Soulby 76561198366643385!!!ATTENTION!!! REP+ is unrecommended, it may cause unknown issues REPENTOGON is necessary - What's in it? · 11+1 characters with complete unlock-trees! · 200+ items! · 3 transformations! · 6+1 bosses! · 11 challenges! · 2 curses! · More rooms! · More poops! · More bugs! - What's in the future? ·...13.4k downloadsupdated 17 d ago
- Better Clicker!by im_temThis mod reworks the Clicker item. Now you can choose the character you want to turn into! But be careful with who you choose since Clicker is now one time use item!13.3k downloadsupdated 6 y ago
- Red Heart Priority on Mausoleum Doorby Does what's advertised. The mausoelum door will now prioritise red hearts over any other heart types. You can still use other heart types though.13.3k downloadsupdated 5 y ago
- Jerma over Envyby 76561198913956830i just wanted to put him in the game somehow13.3k downloadsupdated 23 mo ago
- Better Jupiter Forgottenby lesserStaradds a unique costume for Jupiter when playing as the forgotten by slightly editing the big bony sprite (the head at least) to do - recolor the sprites - make a side sprite for the head13.3k downloadsupdated 5 y ago
- Tainted Lost Tweaksby Max from SamundmacTainted Lost is more Glass Cannony! Tainted Lost now starts with the Wooden Cross trinket and the Sacred Orb, allowing them to collect more powerful offensive items and have 1 guaranteed hit per floor! If you want to make the Lost gulp said trinket, download another mod of similar function or see...13.3k downloadsupdated 5 y ago
- Biblically Accurate Angelsby FrankenThis mod change the sprite of Uriel and Gabriel to look like angels from religious books like the bible or revelation! The fallen angels also have their own unique resprite! I will keep updating and polishing the sprites so let me know any issues or ideas you have The origin of this mod starts wi...13.3k downloadsupdated 3 y ago
- Always Angel/Devil Roomsby littlenewbieGuarantees Angel and Devil rooms by starting with both Goat's Head and Duality.13.2k downloadsupdated 8 y ago
- Start Item Optionsby ۩۞۩ FerMod ۩۞۩This mod adds four initial items options to choose from in the starting room. These items are spawned from the treasure room item pool. Because of this, the treasure room of the first level is always empty. Although, when the level has the 'Curse Of Labyrinth', the second entered treasure room wi...13.2k downloadsupdated 4 y ago
- Lost Heartsby pie_flavorThe Lost doesn't have health, but he can't do anything with hearts like the Keeper can. This mod changes that! Now, if you pick up (while not holding Ctrl/ZR): a black heart - breaking the mantle will give the Necronomicon effect a golden heart - breaking the mantle will spawn a few pennies and a...13.2k downloadsupdated 5 y ago
- Devoid: Apollyon Reworkby 76561198412573006Devoid This Apollyon rework centralises around making the character more fun to play by introducing a new gimmick to the character, and changing the void active item to both be less complicated usage whilst also tying in with the new gimmick. Locust Portals Apollyon now starts with an innate abil...13.2k downloadsupdated 3 y ago
- Stoneys Hate Bombsby ☢ Nato Potato ☢Pretty simple, stoneys and other invulnerable stone enemies like grimaces can now be killed by explosions. You can set which invulnerable stone enemies are weak to explosions, as well as whether or not Hagalaz runes and Sulfuric Acid shots hurt them by using the Mod Config Menu, or just use below...13.2k downloadsupdated 4 y ago
1.6k tweaks mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

