The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth tweaks mods
Everything filed under tweaks by its own author, ordered by how much it is used.
1,627 tweaks mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.6k tweaks mods
- New Leviathan Transformation Animationby flambamambaAs per request, I have made this mod stand alone. Enjoy!6.3k downloadsupdated 9 y ago
- Stop Blowing Up My Donation Machine (Spawn Dollar in Shops)by TorTired of bombing your donation machine when you have Dr. Fetus/Ipecac/Golden Bombs? Want to fill your donation machine super fast? Wanna just cheat money for shops? This is the mod for you, probably. This mod puts a dollar in front of the donation machine in your shop every floor. UPDATE TO MOD:...6.3k downloadsupdated 5 y ago
- Animated Mimicsby Lo-fi LongcatAnimation: Lo-fi Longcat Coding: Jacobsmob Given that mimics are my favourite enemies in video games it was such a disappointment when I saw that they were implemented so poorly in Afterbirth+. So, I whipped up this animated version of the iron chest turning into the spike chest that plays when y...6.3k downloadsupdated 10 y ago
- The Boosting Of Isaacby MrMigglesBoost your Isaac run with 150+ different combinations of between 1 and 4 items at the start of each run! Designed to be a background mod while testing out other mods/characters, or if you just want to play an OP run, the items spawn on pedistals so you can decide which order or how many to pick u...6.3k downloadsupdated 10 y ago
- Faster Boss Deathsby DevSimple mod, bosses no longer take eons to die. All bosses, including modded ones now die 30 times faster (configurable)6.3k downloadsupdated 3 mo ago
- Cheaty Speed Runby PeeziestWant to finish a Lost run in about 10 minutes? Spawns with lots of resources and several strong items. Makes running through the game quick and easy. Specifically, this mod: - Spawns Rock Bottom, Soy Milk, Godhead, and 15 other strong items in the starting room - Spawns The Dollar in the shop eve...6.3k downloadsupdated 5 y ago
- INNER SANCTUM (Soundtrack Overhaul)by HengusMA passion project developed tirelessly over the span of a few months, INNER SANCTUM is an original interpretation of the game's score with a heavy emphasis on action and atmosphere befitting of the game's derelict, melancholic vibes. Every major track in the game is complete! The entire soundtrac...6.3k downloadsupdated 23 mo ago
- MawOfVoidUnnerfby KeinNiemandUnerfs maw of the void so it works like it did before repentance. Adds back the 5% chanche to drop Black Hearts when killing enemys Gives a Flat +1 Damage up instead of a regular +1 damage up becouse there is no easy way to do regular damage ups.6.2k downloadsupdated 5 y ago
- Actives are Pocketed!by PermamissSets the active item of all characters to be a pocket item instead (if there is not already a pocket item for the character). Compatible with XML mods that change starting item Does not activate in Challenges Clicker/Ankh/etc. normally remove your pocket active; this mod gets around that issue Th...6.2k downloadsupdated 5 y ago
- DDLC Isaac Mod - Main Menu Replacerby CrashpunkA simple Main Menu replacer to fit the theme of DDLC. This is an optional part of the 'Doki Doki Literature Club - Isaac Mod.' DDLC Isaac Mod Complete Collection6.2k downloadsupdated 8 y ago
- Hush Treasure Fixby EsauEnjoyerFixes Pay to Win, More Options, Golden Horse Shoe and Broken Glasses not working in Blue Womb treasure rooms. Pay to Win spawns a restock machine. More Options spawns an item choice. Golden Horse Shoe has a 15% chance to spawn an item choice. If you have REPENTOGON, Broken Glasses has a 50% chanc...6.2k downloadsupdated 2 y ago
- Color Menu (not working, no time to repair :c)by raNn- mod isn't working now - I have no time to update it, sorry :c Hi! I just add Forgotten to beautiful mod "colored character select". So all credits go to El Calitros (and heres link for orginal mod here ) All feedback is welcome. I'll try to patch all bugs :) (Also, don't look at Endor...6.2k downloadsupdated 7 y ago
- Aaron's Custom Respritesby AaronRuinsLivesWhat is this? This mod is a collection of resprites made by me in my freetime because why not. It changes everything from items, pickups, UI, and even the title screen! If you have any issues or suggestions, or you want some help with some of your own projects, just DM me on Steam Important This...6.2k downloadsupdated 3 y ago
- Start with Mom's knifeby BarjuhStart each run with Mom's knife Collection with all my Start with mods :6.2k downloadsupdated 3 y ago
- Ashpit Corner Fixby 76561199017158324have u ever noticed that missing corner in ashpit? it makes the game unplayable!! luckily i have just the right thing for u :) enjoy!!♥6.2k downloadsupdated 18 mo ago
- Sortable Familiars [AB+/Rep]by SentinelYou've got all those little familiars following you.. but what's the fun if you can't boss them around? Get more control over your familiars! This mod allows you to change the order of your followers. Why? Well, it actually has a couple of good uses. Some familiars are more effective at certain p...6.2k downloadsupdated 5 y ago
- Tiny n' Cool Packby MerloHello there, and welcome to the "Tiny n' Cool" pack, presented by Merlo and Tritonis! Join our community Discord Server! The goal of this small pack is to incorporate some of the rather simple, yet fun ideas we see on the Binding of Isaac's Subreddit (plus some of our own), and incorporate them a...6.1k downloadsupdated 8 y ago
- Fancier Itemsby 76561199017158324Gives some items a fresher, fancier look. Im aiming to re-sprite more items, this is just the beginning!! currently changes these: the sad onion spoon bender blood of the martyr magic mushroom 1up mushroom lord of the pit brimstone ♥♥♥♥♥ of babylon spirit of the night abaddon deaths touch missing...6.1k downloadsupdated 7 d ago
- Head of The Keeper Costumeby 76561199003542053Changes Head of the keeper costume based on your coin counts + spins!. If you know how to code this better let me know.6.1k downloadsupdated 3 y ago
- eve respriteby jacksondaxhackerA simple resprite for my girl Eve, currently normal Eve and Tainted Eve are done, in the future perhaps I can try to resprite other characters.6.1k downloadsupdated 3 y ago
- Boss Resprite - Mask of Infamy + The Visageby FerpeResprited and reanimated a glorified enemy located in Necropolis for no good reason. I really hope they update this boss so that it's an actual boss and not whatever this is. Complete with its champion and Delirium variants! If you don't like the reference to its concept art version I put a norma...6.1k downloadsupdated 4 y ago
- Achievement Randomizerby ZamieAchievement Randomizer Achievement Randomizer is a mod that gives you the experience of playing through the game from scratch, unlocking each item one by one in a randomized way. This mod does not simply randomize all of the vanilla achievements. Rather, it has custom objectives and custom unlock...6.1k downloadsupdated 3 y ago
- RockBottomStartby MINDS3THello! This is a very basic mod made for a friend, all it does is give all characters, modded and vanilla, Rock Bottom at the start of each run. Should be compatible with just about anything seeing as it's not very complex! This mod is purely meant for fun, I didn't see anything when I searched o...6.1k downloadsupdated 5 y ago
- Ulith Fixby LiamdotMy friend recently thought that "Lilith" was called "Ulith" because of the confusing character label. This mod makes it very easy to read, so new players won't get confused!6.1k downloadsupdated 2 y ago
- Start with Schoolbagby BarjuhStart each run with Schoolbag Collection with all my Start with mods :6.1k downloadsupdated 4 y ago
- Deltarune Almond Milkby ADudeCalledLeoPractice some self-care! Changes the Almond Milk item to look like the healing milk featured in Chapter 1 and Chapter 2 of Deltarune. (NOTE: This mod does not make Almond Milk heal you.)6.1k downloadsupdated 5 y ago
- [DON'T USE IT]Glitched Crown Slower Rerollby 76561198813796283(SPA) Este mod hace que los cambios de items hechos por Glitched Crown sean más lentos En vista de que alguien más hizo un mod mucho mejor que el mío, este dejará de recibir soporte, mejor usen este otro (ENG) This mod makes Glitched Crown's rerolls more slower In view of the fact that someone el...6.1k downloadsupdated 4 y ago
- Succubus Unnerfby hogMakes Succubus' aura damage scale with the damage stat again not updating this anymore, use at your own risk, beware etc etc6.1k downloadsupdated 6 y ago
- Fast IV bag, Portable Slot and Kamikaze!by ☢ Nato Potato ☢Very simple. The cool-downs for IV bag, Portable Slot Machine and Kamikaze! are drastically reduced, allowing you to use them more quickly, you can even just hold the button in and they will be used repeatedly. (it works without affecting the players damage cooldown so you will still be protected...6.1k downloadsupdated 6 y ago
- Four Souls Bombsby 76561199058109437Resprites bombs and troll bomb to resemble more of that of the fours souls cards. This includes all standard bombs and some slight tweaks to a few others. (does not change any bomb item sprites) THEIR EYES GLOW IN THE DARK HOW COOL IS THAT? Changes: -Bomb pickups and costumes -Giga bombs -Mega Tr...6.1k downloadsupdated 3 mo ago
- GreedStartPickupsby IsterbollenTired of never getting any pickups in greedmode? Don't want to spend your precious money on keys and bombs? Me too. This mod simply adds 6 bombs and 6 keys to the first room of greedmode. Enough for a comfortable run but not so many that you can't ever run out. It should work for greedier mode bu...6.1k downloadsupdated 5 y ago
- Cuter Blood Puppy Spritesby SkiiveDo you love Blood Puppy but don't love how he loses his cuteness upon changing phases? With this mod he will forever be cute! This mod changes the textures for phases 2 & 3 of Blood Puppy plus the death/bestiary sprites. Blood Puppy my beloved~6.1k downloadsupdated 6 y ago
- Faith Dogma Reskinby 76561198973457670replaces the dogma boss graphics with purist the spectres faith the unholy trinity reskin of it faith crucifix mod: faith music mod:6.1k downloadsupdated 3 y ago
- TBoI: Radbirth [NUCLEAR THRONE]by majoThe Binding of Isaac: Radbirth is a mod that was made for Afterbirth in 2016 by majofps and EthanTheLion. Over the past week, it has been ported over and updated for the new DLC, Afterbirth+! Radbirth's Features: - ALL NEW Nuclear Throne characters - ALL NEW Challenges - Nuclear Throne themed ite...6.1k downloadsupdated 10 y ago
- Aero's Locust Expansion Modby 76561198881880834Important Note: Anybody new checking out this mod, I recommend you to download the Abyss++ mod instead of this one. Reasons why: Abyss++ has its content mostly finished. I don't have the motivation to finish the rest of this one. Abyss++ is based off of this mod, so you would be getting a similar...6.1k downloadsupdated 5 y ago
- Loud Ni#ra Over Larynxby 76561198345921126Simple mod that replaces the Larynx scream with Loud Ni#ra. I cant make videos for this kind of stuff since my computer cant handle it, but Im sure you can imagine what it sounds like.6.0k downloadsupdated 5 y ago
- Epiphora Bufferby 76561198855158338Epiphora is one of the least synergistic items in the game, so I thought it's time someone fixed it. Epiphora now has 5 buffer frames (13 for Brimstone) where the tear multiplier doesn't go away, meaning you can take your finger off the fire button to use both chargable and tappable items, then q...6.0k downloadsupdated 20 mo ago
- Fixed Guaranteed Start [REP+]by 76561199054343421This is a fix/remake of the original Guaranteed Start. Any advice let me know! Features: - Replace the item ONLY in the first Treasure Room of the run *you go in* (that means u can skip for planetarium) with a 3 or more quality item. - It works with Greed Mode :D (read below) - Now it works with...6.0k downloadsupdated 4 mo ago
- [REP] Guppy Unnerfby MiyukkiReverts nerf of Guppy's transformation, with this mod it works like before Repentance. With mod you have 50% chance to spawn a blue fly after every shot, but it will spawn 2 flies instead of 1 - so there's again same amount of flies like before nerf You can get this modification in my Repentane U...6.0k downloadsupdated 5 y ago
- Cursed Voiceoversby SprSnpr_I edited some voiceover lines to make them . . . cursed All voiceovers have been changed-- outside of cutscenes, naturally All new voiceovers were made using preexisting ones6.0k downloadsupdated 5 y ago
- TBOI; Beyond - Repentant Incubuddiesby Ug-QualtothHello fellow isaakers, this is the Incubuddies Mod, now updated for Repetance!!! (or rather,, remade?! since all the sprites are brand new!! ahahah) SO, what does this mod do???!! Welp basically, every time u take an incubus, they will have the appearance of the character that you have! if u have...6.0k downloadsupdated 5 y ago
- Faster Golden Pennyby IslaTeleports Isaac to a golden coin if he could theoretically walk to it. If the room is cleared when Isaac picks up a golden coin he will start teleporting to all places it appears at. This teleportation respects pathing, so you won't be teleported over cliffs, rocks, poop, etc. Having flight disab...6.0k downloadsupdated 4 y ago
- Uninterrupted Void Music [RGON]by Mr. HeadcrabNow configurable for other stages! It sucks having to listen to the beginning of the void tracks every time you leave a boss or secret room, this mod makes it so that it gets interrupted only by Delirium itself :) This mod does not make music pick up where it left off, since that doesn't seem to...6.0k downloadsupdated 2 y ago
- Mario 1-1 In Isaac!by 『Sora』Adds Mario's first ever platforming adventure level to Isaac! This isn't a rom, it's Mario recreated using the base Isaac engine and physics. You can jump, shoot tears, bounce on enemies, collect mushrooms, and everything in between. Implemented as a separate character named Mario that you play as.6.0k downloadsupdated 5 y ago
- Necromancer Costume(Rep+)by 76561198411462825When I looked through the newest patch notes, I saw a new transformation, and I said, "Where is it? Where is the new transformation costume?" but Edmun Mcmuffin preferred not giving it a costume, so this mod is for people like me who wanted a new costume for the new transformation in the game. Ha...6.0k downloadsupdated 14 mo ago
- The Babies Modby ZamieThe Babies Mod In The Binding of Isaac: Rebirth, there are a ton of co-op babies. Even though most of the babies are only cosmetic and have no special abilities, a tremendous amount of work has gone into designing them, coding them, and creating all of the sprites. This is an area of the game tha...6.0k downloadsupdated 15 mo ago
- Fancy Player Animationsby girl45i remade some of isaac's animations so they look cool now animations i remade : pickup appear(floor start) death sad(bad pills for example) happy(good pills for example) lift item hide item use item jump(how to jump book) fall in(holes for exmaple) jump out(holes for example) light travel(like th...6.0k downloadsupdated 2 y ago
- Dripped Outby OliveRiderDrip has appeared in the basement! Isaac now has a dripped out walking animation THIS ANIMATION IS NOT MINE. It was made originally by NotYourSagittarius, I just edited it Has some character-depentant animations, might make more at a future date. Enjoy!6.0k downloadsupdated 18 mo ago
1.6k tweaks mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

