The Binding of Isaac: Rebirth gameplay mods

Everything filed under gameplay by its own author, ordered by how much it is used.

1 gameplay mods, most downloaded first · newest update 6 May 2026

1 gameplay mods

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Treasure Room 4 Choicesby 76561199124338734Reworks the first Treasure Room on Floor 1 into a 4-choice start. - Triggers only in the first Treasure Room. - Replaces the normal pedestal with exactly 4 Treasure Pool items. - Guarantees at least 1 item with Quality 3 or 4. - The other 3 items are random Treasure Pool items. - You can pick onl...5.9k downloadsupdated 6 mo ago

Only one so far. It has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.