The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- [REUPLOAD] Aladar's Syringe Items Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...12.8k downloadsupdated 17 mo ago
- Furtheranceby BennyA complete overhaul of the The old Furtherance MOD originally released in 2022. Coded from the ground up under the experienced eye of a single coder with the power of REPENTOGON, this new release breathes new life into every corner of the original MOD to create a sizeable quality package of conte...12.7k downloadsupdated 15 mo ago
- the binding of Cirnoby 御坂14144号Cirno, The smartest & strongest girl. At least she believes in that xd. This MOD includes a NEW character Cirno (Nihiri version) And her private treasure Ice Frog (not the one who is making DotA) Cirno starts with 3 soul hearts; Uranus;(冻符「Perfect Freeze」) The Inner Eye & The Wiz; (冰符「Icicle Fall...12.7k downloadsupdated 3 y ago
- [AB+] [REP] Squash for Daddy longlegsby 76561199192861745Changes "Daddy longlegs" collectible sprite to squash from PvZ, also works on the boss with the same name12.7k downloadsupdated 12 mo ago
- Glowing Itemsby SprSnpr_***While this mod does not affect any items added in Repentance, it does still work in Repentance*** This dandy little mod makes certain items look like they're glowing a little more. Items affected include: Devil symbol items Angel symbol items Zodiac symbol items And many more! There are, as yo...12.7k downloadsupdated 6 y ago
- Black Holeby Custom PhaseIMPORTANT UPDATE: THE ITEM IS OFICIALLY IN THE GAME NOW, YOU DONT NEED TO SUBSCRIBE TO THIS MOD ANYMORE. Thanks for the support and kind words everybody! Screenshots/video are outdated, the item has been significantly nerfed with the latest updates. Black Hole is a throwable active item similair...12.6k downloadsupdated 10 y ago
- Start with Death Certificateby AsukaReplace the item in the first treasure room with Death Certificate12.6k downloadsupdated 6 y ago
- Pog Bottomby Phno 🐙Now rock bottom can pog even harder Mod changes the sprite of rock bottom, effect remains unchanged. Credits for sprite and idea goes to u/Toster42512.6k downloadsupdated 5 y ago
- [AB+/Sorta Rep] Fuck Invincible Enemiesby BennyAdds an item called the Steel Hammer. Finally damage invincible enemies directly! I might update this with a redesign if I get around to it.12.6k downloadsupdated 6 y ago
- pomni bozoby 76561198858278480this mod changes the appearance of the item "bozo" to resemble the character Pomni from the web series "the amazing digital circus" and that's it12.6k downloadsupdated 3 y ago
- IM FUCKING INVICIBLEby GodWladiFeel the power of invincibility like never before with this custom mod! Sundowner from Metal Gear Rising: Revengeance will support your with his sexy voice. When you activate invincibility items like Book of Shadows, My Little Unicorn, or the Algiz Rune, you'll be immersed in intense sound effect...12.5k downloadsupdated 4 mo ago
- ![Touhou] Flandre as Azazelby 76561199075257239This mod was replaced Azazel and tainted Azazel's tiles with Flandre Scarlet.It also replaced the tiles of 2 items,2 trinkets and devil beggar If you're afraid of Flandre getting ugly because she picked up some weird items, I recommend you subscribe to this mod: Old Wardrobe Have a good time!12.5k downloadsupdated 2 mo ago
- Isaac Doing Thicc Omni Man Memeby PEZIsaac Doing Thicc Omni man meme with Gnawed leaf 🥵 - Special thanks to my lil bro who helped me with the idea.. thank you xuxetumare ❤️12.5k downloadsupdated 3 y ago
- Master Sword and Hylian Shieldby JakoBablesReplaces Trinity Shield with Hylian Shield from The Legend of Zelda series as well as the Spirit Sword with the Master Sword! (No sound effects included, may be updated if popular enough)12.4k downloadsupdated 5 y ago
- Cricket Transformation (Omnibirth Preview)by majoThe Cricket Transformation mod is part of a MUCH larger mod called Omnibirth, this is a teaser! For more information on Omnibirth, join the Discord server! Cricket's Eye - "I see all" + Reveals the Boss room on Isaac's map + Prevents Curse of Darkness and Curse of the Blind Cricket's Claw - "It s...12.4k downloadsupdated 10 y ago
- Portal of Friendsby NickSquigglesNOTE: This mod is currently not supported in Repentance. Instead, use 'Lil Friend Portal' mod here: ---------------------------------------- Fight off the masses of portals with your own! Portal of Friends is an active item that creates a friendly portal which spawns friendly, charmed enemies. Al...12.4k downloadsupdated 10 y ago
- missingno respriteby 76561198876704734a missingno resprite to make it look like the actual missingno commissions still open!!!12.4k downloadsupdated 4 y ago
- Sacred Diceby MorcEver wanted an item that combines the Sacred Orb and Eternal D6 - and all that in the shape of a new dice?? No? Well we made it anyway! This brand new quality 4 active item lets you re-roll items into a random item of +1 quality higher than before! But it comes at a cost.. - There is a 60% chance...12.4k downloadsupdated 2 y ago
- Risk of Rain 2 Items and Chests [REP - SURVIVOR UPDATE WIP]by CaMpeRThis mod adds 50+ Risk of Rain 2 items which are stackable with themselves to increase the effectiveness of the items! These items will only spawn via the Risk of Rain item chests which only spawn at the start of the floor (or with special conditions). These chests will not replace any of the van...12.3k downloadsupdated 4 y ago
- Atomic's Halo Respriteby AtomicrowA small resprite mod I made for personal use, making the Halo more visually consistent with Uriel and Gabriel's halos.12.3k downloadsupdated 3 y ago
- Only Modded Itemsby HiHowAreYouThis mod will only work if you have other item mods installed! This mod removes all items from the base game, with the exception of items dropped by bosses. This is to ensure you get the stat ups needed to progress. I recommend you browse the workshop for cool items! There are a lot!12.2k downloadsupdated 6 y ago
- Foks' Booster Packby FoksRequires to work! The mod aims to add simple vanilla-like stuff into the game, currently adds: - 48 new items! - 19 new trinkets! - 2 new cards! - 1 new pickup! Check out the Isaac Guru page for more info! These mods are supported: - External Item Descriptions - Accurate Blurbs - Hush's Item Pool...12.2k downloadsupdated 12 mo ago
- Nyan Tech-Xby c:\ayooo, re-sprite of tech-x with cat-ears.12.2k downloadsupdated 3 y ago
- MF DOOM maskby 76561199569790089Hey everyone! here is my first mod ever! Its a very simple resprite and it does what it does: it changes the sprite of the item infamy as well as the costume of it to the mask of the rapper MF DOOM. The idea came from a Reddit post and seemed like a fun challenge for my first mod, so thats what i...12.2k downloadsupdated 19 mo ago
- Start with Holy mantleby BarjuhStart each run with Holy mantle Collection with all my Start with mods :12.2k downloadsupdated 4 y ago
- Start with Rock bottomby BarjuhStart each run with Rock bottom Collection with all my Start with mods :12.2k downloadsupdated 4 y ago
- (AB+) Supremacy+Angelby BroskiPlays on ROG AllyAre you always complaining about the bad angel items in the original isaac game? Are you searching for those angel items that really award your effort of sacrificing another devil deal with a truly amazing power that was gifted to you by the angels? Well we got you covered. Introducing the Suprem...12.2k downloadsupdated 10 y ago
- Gory respritesby RatfeedYes, after over a year of laziness, I updated it.12.1k downloadsupdated 2 y ago
- UMA Overhaul Succubusby TeddyTweakerAttempts to start a flame war will be deleted This sprite is from UMA Overhaul, I didn't make this. I have a soft spot for the Succubus sprite from UMA Overhaul, but the mod is long since deprecated and in that time there's been many other graphical overhauls I prefer to it. The creator's given a...12.1k downloadsupdated 3 y ago
- KURWA (over curse of the blind)by 76561199183319866The best swearing in the world is now in The Binding of Isaac When you are cursed, instead of a question mark you see "kurwa" and at the same time the sound "o kurwa" is played Thanks to bogdanrudyka for helping out with the mod! Inspired by the mod FUCK YOU (over Curse of the Blind)12.1k downloadsupdated 4 y ago
- Curly from Mouthwashing as Cube Babyby 76561198913956830he's breakdancing12.0k downloadsupdated 2 y ago
- Mammon's Contractby MerloMany people on reddit have amazing ideas, but can't code them. I, on the other hand have zero ideas, but could code them all. Enter the Reddit's Community Mods Project, where I'll go and find the best ideas from the community, and bring them to life! Check out the full Community Mods Collection o...12.0k downloadsupdated 9 y ago
- StrawPack 2by MozzieAdds 6 items, 5 trinkets and 1 challenge to the game! Art and thumbnail by Aczom. Code by Strawrat. This mod uses a cropped version of the following sound effect from Freesound: "01543 flying dragon" by Robinhood76. NOTE: If you already have any of these items individually installed, be sure to d...12.0k downloadsupdated 9 y ago
- Baseball Batby ☢ Nato Potato ☢The Baseball Bat gives you the ability to use a melee attack like forgottens bone club. Just like forgottens bone club it has a bit of knockback, it will knock away bombs, it will break fires and poops instantly, it can open spiked chests without hurting you, it can hit enemies or pick up coins/k...11.9k downloadsupdated 4 y ago
- Even more bumsby ☢ Nato Potato ☢This mod adds 3 more bums to the game, Dead Bum, Robo Bum and Holy Bum. Dead Bum: gives 1 bone heart per 2-4 soul hearts (half hearts count as 1) Robo Bum: gives 1 charged key per 1 battery Holy Bum: gives 1 eternal heart per 5-10 red hearts (half hearts count as 1) If you get all 3 bums they fus...11.9k downloadsupdated 5 y ago
- Vazkii's Item Packby VazkiiThis mod adds a few new funky items to the game: - Eye of the Subconscious: Isaac stops being able to fire manually and will fire like Demon Baby. (Devil Deal Pool) - Remote Control: Bombs move in the direction of Isaac's tears. (Shop Pool) - Bleeding Edge Tech: Technology that is aimed towards I...11.9k downloadsupdated 10 y ago
- delirium drops r keyby gan_regenas per a request on reddit. for those of you who wanna get completion marks easier but in a more spicy way. 💖 (pretty much just an alternative to the every floor mod.) definitely works in repentance, should work in ab+, dunno why it wouldnt. edit: r key isnt in ab+ to begin with oh my god lol11.9k downloadsupdated 5 y ago
- More Milkby XalumChocolate and soy not good enough for you? -- Introducing the More Milk mod. 8 new flavours of milk await for you to try: Almond Milk: - Increased shotspeed Banana Milk: - Increased speed Coconut Milk: - Increased damage Strawberry Milk: - Increased tears - +1 red heart container Vanilla Milk: -...11.9k downloadsupdated 9 y ago
- Sprinklerby KieranSprinkler is an active item which is able to be put down in a room. It rotates in a circle spraying tears in each direction, and synergises with the player's tear effects. It also currently works with Mom's Eye, Loki's Horns, Tech X, Dr. Fetus and Brimstone, and includes custom models for certain...11.9k downloadsupdated 10 y ago
- The Binding of Steve (Rep. version) : Minecraft Crossoverby Ly FechaIf you like my work, please consider clicking on the like, favorite or even reward button. THIS IS THE REPENTANCE VERSION. Afterbirth+ version : Warning : Due to game and api instability, sounds and some items have been removed temporarly. They will probably be added back after some Repentance up...11.8k downloadsupdated 4 y ago
- Curse Counterplay 汉化模组by 76561199083721642进修归来,现在可以不用手动替换就有汉化了,说,谢谢wofsauge! 之前订阅手动改过文件的可能需要取消订阅Curse Counterplay进游戏再重新订阅 有遇到什么这个mod的EID描述错误可以评论留言11.8k downloadsupdated 17 mo ago
- [AB+ TESTED ONLY] Cannibals!by HiHowAreYouNOTE: I have not updated any of my mods to Repentance. I'm not sure if I will or not. If I do, it'll be after I've explored the update enough, I don't want to get spoiled by testing mods. They consume each other! This mod adds two items, one passive, and one active. Scratch Scratch is a one room...11.8k downloadsupdated 8 y ago
- Bound Soulby ☢ Nato Potato ☢Bound Soul can be found in devil or angel rooms, it gives you a soul familiar that shoots at nearby enemies and if you die you respawn as the forgotten. The soul has the same tear rate, damage and tear effects as the player, but does not change weapon type. (wont shoot bombs if you have dr. fetus...11.8k downloadsupdated 5 y ago
- the saac headby 76561199590469868changes sack head and sacks to the SAAC11.8k downloadsupdated 4 mo ago
- Job application over 2Spookyby 76561198348731500Did i scare you? Resprites 2Spooky to look like a j*b application11.7k downloadsupdated 18 mo ago
- The Philosopher's Stoneby edinWorks well with my Trinket Stacking+ mod, which give more unique effects to golden trinkets! The Philosopher's stone is a new active item in the shop item pool that can be used 3 times. Upon use, it will turn some of the pickups on the ground into their golden variants! This includes coins, keys,...11.7k downloadsupdated 5 y ago
- Ness - Playable characterby ☢ Nato Potato ☢Play as Ness, the psychic hero from Earthbound! Ness comes prepared with the psychic abilities of Telekinesis and Ludovico Technique, as well as the Schoolbag and the Baseball Bat. (if you have the Baseball Bat mod installed and enabled) It can be a bit of a challenge sometimes to balance between...11.6k downloadsupdated 4 y ago
- Psy Fly In Menuby 76561198369844905Changes default black fly in main menu to Psy Fly. Thats it. You might also like Psy Fly Title Screen with animated fire:11.6k downloadsupdated 5 y ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

