The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Totally Unnecessary But Nonetheless Epic Giga Bomb Synergiesby 76561198876704734Funnyman Modding Enterprises is BACK! With another BANGER! (no pun intended) (they also do commissions so hit them up lol) This mod adds 12 new synergies between Giga Bombs and bomb related items. The list is as follows (and yes, they do stack.): Bob's Curse Fills the room with toxic gas that dea...62.8k downloadsupdated 22 mo ago
- Dio Brando (JoJo no Kimyou na Bouken) (Not Repentance-Compatible)by Badass PhysicistDio Brando, the antagonist of Phantom Blood and JoJo's adoptive brother, known for rejecting his humanity to become a vampire and rule THE WORLD. Dio Brando starts with 2 bombs, 1 key, 3 black hearts and 1 red heart and a pack of vampiric powers. The mod includes Phantom Blood's ending, new sound...62.3k downloadsupdated 8 y ago
- No Empty Pedestalsby ☢ Nato Potato ☢Very simple. Removes empty pedestals from the room instantly, preventing them from getting in the way. Can be helpful if an item spawned in a not so great location in the room and having to walk through it is annoying. Also allows multiple items to be spawned in the same location without a bunch...61.0k downloadsupdated 20 mo ago
- The Binding Of Pokemon + (NO LONGER SUPPORTED)by TechTHIS VERSION OF THE MOD IS NO LONGER SUPPORTED, THANK YOU FOR HAVING DOWNLOADED THIS AMAZING MOD AND PLAYED IT!!! If you want to play the sequel, here it is, The Binding Of Pokemon + Legends Expansion (WIP) It'll be worked on by the amazing Nalejandro3 ! I'll still help on things too ! Mod by Tho...60.7k downloadsupdated 6 y ago
- winston as the monkey pawby gummers"hi there" - winston overman59.7k downloadsupdated 4 y ago
- True Co-op Treasure Roomsby ☢ Nato Potato ☢When you play a co-op game using Repentance, or the true co-op mod, treasure rooms will spawn items in the corners of the room instead of just one in the center, each player can only go near one corner so all players get one item each. It also takes into account double item rooms and more options...59.5k downloadsupdated 10 mo ago
- Silasby MaddogsBring the world of mad science into The Binding Of Isaac with Silas! You can use four different potions to storm through the levels: Green potions create creep at a long range Red potions are thrown far, but explode on contact Yellow potions can apply any status effect at medium distance Blue pot...59.0k downloadsupdated 10 y ago
- Sharp Plug Indicator [Rep]by spaghetti wareAdds a sprite near the spacebar item chargebar when you have the 'Sharp Plug' item or effect from something like lemegeton. Works for Esau/player 2 in co-op. Repentance is required for this mod to work. Pre-repentance version58.8k downloadsupdated 20 mo ago
- tranformations respritesby Xtrikefor those little times you get them, at least you want them to look good, dont ya? this mod resprites the transformations of: guppy spider baby bookworm beelzebub spun mom leviathan conjoined fun guy bob seraphim ToDo: resprite transformations of characters as keeper or dark judas to fit the resp...58.2k downloadsupdated 5 y ago
- Mr. Bellyby 76561198855621135A mod for Lazy mattman. NOT MY CODE!58.0k downloadsupdated 4 y ago
- [Rep] Sacred Dreams Act Iby 76561198354826432Prepare to delve into Isaac's dreams in this unofficial (duh) prequel to the original game: A new Character! Unlockable achievements! 20+ items! New trinkets! New pickups! New music! And more... The Dream Guard starts with a pocket active item: Sand Pouch Use it to apply a new status effect somno...57.9k downloadsupdated 23 mo ago
- John Rod For Paperclipby 76561199097252825A popular Manga Series Jojo's Unique character John Rod Over Paper Clip Trinket57.9k downloadsupdated 4 mo ago
- Arena Mode (AB+ Only)by SentinelThis Mod adds a whole new Mode: In the first room: Choose your items - You must pick 1 out of 5 items - You will get 10 items - After picking 10 items you will go to the arena - there are 3 new items and 1 new enemy In the arena: Fight of Monsters - There are 20 waves of Monsters - The waves will...57.8k downloadsupdated 10 y ago
- Unlock all items and characters! (Updated for Repentance Plus!)by 76561198389860083Compatible with last patch of Repentance+! Im updated it again, finally. It still can be buggy for someone, but qualities of items, pools and etc. is fixed, have fun! Version to unlock only items This mod unlock ALL ITEMS AND CHARACTERS in game without affecting on achievements If you turn off th...57.3k downloadsupdated 21 mo ago
- Sewing machineby UdolfieMake your familiars stronger ! The Sewing Machine is a brand new machine which allows you to upgrade your familiars during a run ! This mod include also 3 new items, 5 new trinkets and 3 new cards related to the Sewing Machine. -------------------------------- The sewing machine act like a slot m...57.2k downloadsupdated 3 y ago
- Anime Thunder Thighs!by ViscerANow Thunder Thighs has a sprite with actual thighs. Which is something we all want, honestly. Complete with an item sprite, and a unique costume! Crush rocks with your thighs, and make your enemies wish they were in their place.57.1k downloadsupdated 6 y ago
- Baelby hippocrunchyYou've decided to throw away your old identity and wear a completely new face. The only problem is that it follows you everywhere. As Bael, the pools are flooded with over 80 Cursed Cat items! A mix of high risk/reward, useless, to just plain bad. The Cat insists you must take every free item you...56.8k downloadsupdated 4 mo ago
- [AB+] DDLC Isaac Modby CrashpunkOUTDATED! DOES NOT WORK WITH REPENTANCE! DOWNLOAD THE NEW VERSION! >>>Doki Doki Repentance<<< Featuring new items, Tainted Dokis, Birthrights, many bug fixes and reworks! --------------------------------------------------------------------------------------- Doki Doki Literature Club! Isaac Mod (...56.2k downloadsupdated 5 y ago
- 18+ MODby 76561199059088718This is a mod that changes the game's sprites to fit the 18+ theme. It affects the appearance of enemies, bosses, characters, items, and many other small details. This mod is a new version of an old project, invented on April 16, 2022, on which I worked. For a long time, I did not touch this mod...54.2k downloadsupdated 15 mo ago
- !Rebirth Items Vectorized!by EMORYRebirth Vectorized! replaces all item sprites with rasterized vector art similar to that of the original Flash game, but with vibrancy of Rebirth's sprites. New art for all of Isaac's items! Check out www.cormacillustrated.com/ for a gallery of all the artwork Modded items may be invisible and ne...53.9k downloadsupdated 4 y ago
- AscalonSpearby SinstharAscalon (Spear of Justice) is not an overpowered weapon : it's very good against multiple enemies, less in 1 versus 1. Wait until it falls from above and grab it to perform a powerful whirlwind, yeah ! But beware ! Don’t go too close, this is a melee weapon ! Synergies : - Tears Damage (10x when...53.9k downloadsupdated 10 y ago
- SucQTbusby IvyHas the plain old, angry-looking Succubus of Afterbirth been bothering you with its completely normal appearance? Are you mad that Succubus's deal cost was raised to 2 hearts in Repentance and want something to really make it worth the HP? Worry no more, because there is now a solution for these...52.0k downloadsupdated 6 y ago
- IPECAC Community Modby pedroff_1(If you're looking for the Afterbirth+ Version, click here!) (If you have the Transformations+ API and/or Mod Compatibility Hack, those are no longer required nor supported) Welcome to the IPECAC Community Mod! The IPECAC Community Mod is a mod focused around the community, and as such, a large p...51.0k downloadsupdated 3 y ago
- Hydrophobicity (ADDED IN BOOSTER 5)by MaddogsAdds an entirely new tear effect to the game - Bouncy tears! Hydrophobic tears are different to rubber cement in that instead of flying and bouncing off walls, they are very heavy and bounce off of the floor! The tears will bounce multiple times before finally losing all their mass and disappeari...51.0k downloadsupdated 9 y ago
- awesome cursed skullby im so coolHave you ever wished that the Cursed Skull trinket was just a little bit more awesome? That instead of just being some plain skull, it instead looked much cooler and also vaguely resembled Jim Carry? Well look no further! Also I may or may not have made the sprite a little too big, but I think it...50.9k downloadsupdated 3 y ago
- Devil Keysby 76561198995475535Since Repentance released, Angel rooms have become the new meta, with most players opting to skip devil deals entirely for better and cheaper angel items. When going for Mega Satan especially, devil deals are often ignored completely to even get a half decent chance at getting both angel key piec...50.5k downloadsupdated 4 y ago
- DeadGod Helperby ayteNew version available here : Spot missing items! Easily spot items that were not previously picked up on this savefile. Very useful when you're trying to get a second or third Dead God. Now supports modded items, and integration with Repentogon! I made it mainly for myself, because it was annoyin...50.4k downloadsupdated 3 y ago
- Missing Item and Character Chargebarsby nimbusAdds chargebars for items that miss it: Lead Pencil Shard of Glass Placenta Breath of Life No. 2 IBS Kidney Stone And for Tainted Samson berserk Mod fully supports mod config menu Original creator of this mod deleted it for unknown reasons, reuploaded it and fixed a lot of bugs in it. Enjoy!50.2k downloadsupdated 2 y ago
- (DESCONTINUADO) !!~Descripcion de objetos Repentanceby juve_pc---External item descriptions in spanish--- (A partir del 01/02/2022, este mod también será monitoreado por la usuaria Kotry) Este es un Mod que muestra en la pantalla la descripción de: - Objetos (Items) - Píldoras - Cartas - Trinkets - Habitaciones especiales A su vez, incluye nuevas caracterís...49.8k downloadsupdated 5 y ago
- The Cursed Collection!by PreynYour sins are beyond the grace of god. The cursed collection is here to punish you! This mod adds a collection of immoralities to the game including: 2 new trinkets 3 new active items 13 new passive items Endless sacrilege Interactions - This mod has support for both “External Item Descriptions”...49.5k downloadsupdated 2 y ago
- The Rotten Collection!by PreynFear and be disgusted because the rotten collection is here! Features This mod adds a total of 8 new rotten themed items and trinkets! One new trinket Seven new passive items Of which three are familiars Heaps of fun! (and disgust) These new items will appear in a multitude of item pools! But all...49.3k downloadsupdated 3 y ago
- Library Expandedby dpower12Do you want to spice up your libraries? Want to find new interesting books? Are you a nerd? Then this mod is for you! Welcome to Library Expanded! Library Expanded adds currently: 21 new active collectibles 100+ new Library layouts 1 book-like trinket A passive book meant to give unique bonuses t...48.9k downloadsupdated 15 mo ago
- Rainmaker, Playable Character (Rep/AB+)by SuddenlySquid===================================================== Mod is compatible with Repentance or Afterbirth+ but has updates in Repentance ===================================================== Similar to my Siren mod, this mod was inspired by the Antibirth fan-mod-turned-official-expansion. Rainmaker s...48.8k downloadsupdated 5 y ago
- [fish] siren's items over mom'sby fishygot bored sprited a visual of siren over mom's bra's visual when used, also adds themed resprites for a few other mom items replaces sprites and names for: - mom's bra --> siren's bra - mom's underwear --> siren's panties - mom's perfume --> siren's perfume - mom's knife --> chipped horn - mom's...48.5k downloadsupdated 4 mo ago
- Nemesis [for REP]by SinstharNemesis is a new playable character, with her own shooting style ! She works almost like Lilith : she can't shoot, her familiar (some sort of flying mixture) shooting for her. All the items that normally change your tears are now useless ; you must loot Holy Flasks to modify the tears you shoot....48.5k downloadsupdated 4 y ago
- Epic copyright infringementby EthanA basic mod I made that replaces the sprites for some of the items that are refrences to other games with ones that are more faithful. This is my first mod so far so enjoy.48.5k downloadsupdated 3 y ago
- Reworked Curse of the Blindby EMORYReworks Curse of the Blind to now include color coded ? marks that give players a peak at the quality of the item they're about to pick up. This significantly reduces the frustration of CotB by making your item choice more strategic and rewarding player memory, but retains the general challenge o...48.3k downloadsupdated 2 y ago
- Touhou Reverie - Make Good Omissionsby 76561199075257239!! This mod does not support "Repentance+" DLC !! It doesn't mean the mod cannot work with 'Repentance+' DLC. In fact, the mod can run fine, but it has not been adapted to the new content and changes introduced by Repentance+. It is recommended to play this mod with REPENTOGON version 1.0.12e or...47.8k downloadsupdated 9 d ago
- [REP/REP+] Unique Items Port Packby BennyThis pack depends on UniqueItemsAPI in order to function, and does nothing on its own. Be sure to have both installed! Unique Items Port Pack is a package of various well-known Unique Item mods, but the code entirely built for the UniqueItemsAPI. This improves on many issues found within all of t...47.8k downloadsupdated 23 mo ago
- 700,000 Itemsby JelloQuick note about Repentance I will not be updating this mod for Repentance. Not that I didn't want to, or that I lack the motivation. It turns out that Repentance already has something in the game that kinda does what this mod offers, but on crack. I don't want to spoil it too much, so I won't go...47.3k downloadsupdated 10 y ago
- Polyphemogusby Expired DoktorA little polyphemus sprite and costume change mod Inspired by a post by u/Villager_Werman Thanks to u/Kolateak for the polyphmus sprite Costume change by me46.5k downloadsupdated 6 y ago
- [AB+] Eevee!by BennyStatus Update from Benny The mod has, unfortunately, been cancelled for the foreeable future. There has been a lot of work put into the mod since the Repentance demo's last update, but due to mental health issues, I cannot comfortably continue development. Having a second coder on the team or me...46.5k downloadsupdated 5 y ago
- The Lockedby RyouThis mod adds a new character called The Locked! Unlock his hidden potential! The Locked starts off slightly slower, but he has 5 hearts! Unfortunately for him, he can only have soul hearts, however. Regular HP Ups give him a soul heart, though, so not to worry. This all changes, however, when yo...46.2k downloadsupdated 6 y ago
- [AB+] Retribution - 109+ Itemsby XalumATTENTION RETRIBUTION HAS BEEN UPDATED FOR REPENTANCE GET IT HERE: !!! This mod will not function correctly without Mod Compatibility Hack !!! Retribution adds 109 147 brand new items to the Binding of Isaac - ranging from a feeble axolotl friend to a cursed pumpkin mask. Play as Icarus, who star...46.2k downloadsupdated 6 y ago
- The Sewage Collection!by PreynGet ready to be drenched because The Sewage Collection has risen from the dredge! This mod adds an endless current of content to the game including: 1 new trinket 1 new active item 6 new passive items A new pickup “modifier” A new card Interactions - This mod has support for both “External Item D...45.9k downloadsupdated 2 y ago
- MoreBombsby MaddogsAdds 6 new bomb types to the game, each one with it's own quirks, complete with cheesy item descriptions and unique sprites/animations! Fly Bombs Fluttering little blue bombs that spawn multiple flies when they explode, won't spawn flies if you have too many. Spider Bombs Scuttles on the spot bef...45.4k downloadsupdated 10 y ago
- The Quarry Collection!by PreynHave your mining helmet ready because The Quarry Collection has been dug up! This mod adds a rockslide of new content to the game including: 2 new trinkets 2 new active items 8 new passive items Of which 2 are familiars Interactions - This mod has support for both “External Item Descriptions” and...45.3k downloadsupdated 2 y ago
- Balatro Jokers [Rep|Rep+]by CaMpeRWith Balatro Jokers mod you'll be able to enjoy your favorite jokers and the pack opening experience from Balatro! This mod adds the following content: -1 passive item! -1 Character! -24 Tags! -20+ trinkets -15+ pickups -15 DECK CARDS! -9+ planet cards? (Most of them with custom SFX) -ALL 150 JOK...44.9k downloadsupdated 10 mo ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

