The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Black Soulsby FilloaxNOT COMPATIBLE WITH REPENTANCE Mod is currently abandoned as I'm busy working on Revelations This mod adds, for now, 3 items: Spiral sword Heat-ernal life! This single-use item can turn a nearby fireplace into a bonfire. When you die, even on another floor, after using all your other extra lives...44.2k downloadsupdated 10 y ago
- [RGON] (BETA) Tainted Cain Reworkby 76561199679158341What's new?: RELEASE 1.3 Added several new performance modes for the mod, as well as simple quality of life and recipe balance changes. Item weights were adjusted, alt recipes added, and core recipes changed. This mod requires REPENTOGON. If you do not yet have it, get it here. Ever miss the days...44.0k downloadsupdated 20 mo ago
- Rune Roomsby 76561198374458982Enter the Rune Room, a cut room type planned for Antibirth, and claim your rewards! Rune Rooms A new room type that has a 20% chance to replace vaults. To activate the room's unique floor-wide effect, step on the 4 pads located in the room. Alternatively, the giant crystal can be blown up to spaw...43.8k downloadsupdated 21 mo ago
- Custom Lost Soulby 76561199414106467Custom Lost Soul This mod adds skins to Lost Soul for each character, including tainted versions of the characters. Also this mod supports other modded characters Supported Mods: (+REP) Josuke and Crazy Diamond Fiend Folio: Reheated - 500 New Monsters! Revelations Ch. 2 Samael Andromeda (+28 Unlo...43.7k downloadsupdated 2 y ago
- Cystinosisby ScayzeStone tears! This item can be found in item rooms, and will give Isaac stone tears! Besides being a DMG upgrade, these tears also have a chance to cause shock-waves upon hitting an enemy, how cool is that? Great for taking out large swarms of enemies, but careful, much like Ipecac, this item can...43.5k downloadsupdated 10 y ago
- The Golden Collection!by PreynYour greed knows no bounds and has been rewarded. The golden collection has arrived! This mod adds a trove of treasures to the game including: 4 new trinkets 5 new active items 11 new passive items 3 new pickups A new “Slot” machine Eternal pleasure! Interactions - This mod has support for both “...43.4k downloadsupdated 2 y ago
- The Binding of Isaac: The Devil's Harvestby TeamPROBIRTHIntroducing The Binding of Isaac: The Devil's Harvest MOD. Made by a team of elite The Binding of Isaac: Afterbirth+ modders named Team Probirth, this total conversion expansion mod is guaranteed to shake up the now stale meta of Isaac franchise forever by introducing wacky new groundbreaking con...43.4k downloadsupdated 10 y ago
- Spindown Dice Preview (Reupload)by 76561198813796283(ENG) This mod was originally uploaded by Pokemutt, I am not affiliated with him in any way and I do not support the acts he is accused of, I just wanted to keep this mod Muestra junto al pedestal del item a qué objeto se reroleará cuando se use Spindown Dice "I created this since I didnt want to...43.2k downloadsupdated 5 y ago
- A Rotey Packby rotexorA mod with tons of graphical changes, with minimal changes to non-boss enemies. I decided for the sake of cleaning up my mods folder, and not having lots of the same files fighting over which image to flop down, I'd make a pack featuring graphical changes that I like, and merging most of the shar...43.1k downloadsupdated 1 mo ago
- [REP] Русификатор TBoI [УСТАРЕВШИЙ]by NeibernОписание: Подарок от сообщества на 10ти летие Айзека, да и собственно сами Nicalis в скором времени сделают нам подарок ;) Русификатор основан на переводе Русской Вики по игре. По всем вопросам и предложениям писать в специальные обсуждения. Что на данный момент переведено: - Меню - Предметы - Бо...42.2k downloadsupdated 5 y ago
- Satanic Replacementsby 76561198372132417What does this mod do? It replaces some sprites from bosses and items, while also changing their names and pictures on VS screen. Please note that I do not own most of this mod's content, credits and changes will be listed below. Changes List of changes made, I would recommend unninstalling any o...41.8k downloadsupdated 3 y ago
- Ulamby MaddogsPractice your aim with Ulam the Ranger, the first ammo-based character in The Binding of Isaac! Pierce your foes through with the arrows you fire from your trusty bow, charge up shots to increase the damage and accuracy of your arrows, and pick up different items to give them an elemental aspect...41.6k downloadsupdated 10 y ago
- All Modded Items in the Starting Roomby DeadInfinityPlaying with a whole lotta mods and want to test them out without having to bother with finding things locked behind angel rooms or other nonsense? Or maybe you just don't have too much time to play these huge modpacks? Or maybe you want to test your mod and simply don't have the knowledge or pat...41.6k downloadsupdated 9 y ago
- Marshmallowby Jean-AlphonseRoast it ! Flaming marshmallows set enemies on fire. Red fire: shoots flaming tears Purple fire: homing tears Normal & Red fires: tears will extinguish them Blue & Purple fires: only explosions will Original art: Idea:41.3k downloadsupdated 10 y ago
- Curse of the Blind Silhouetteby pedroff_1From (one of) the creators of the IPECAC Community Mod, a scrapped idea many requested to come back, now in standalone form: Reworked curse of the blind No longer feel the frustration of being entirely clueless as to what in the world you're going to take. Now, you can at least make out the silho...41.1k downloadsupdated 5 y ago
- Lost Plushieby SinstharBored to have 10 familiars behind you and having trouble to dodge the enemies projectiles with all this on your screen ? This mod is made for you ! When you get 2 familiars (those who are chained behind you), a "free box" will appear in the first room of the next floor, with a Plushie in it. Take...41.1k downloadsupdated 10 y ago
- The Toybox Collection!by PreynGet ready to play because your toybox has been filled! Features This mod adds a small collection of toys to play with including: One new active item Eight new passive items Endless entertainment! Interactions - This mod has support for both "External Item Descriptions" and "Encyclopedia" to help...41.1k downloadsupdated 4 y ago
- yetanother's External Item Descriptionsby goki_devyetanother's External Item Descriptions This mod does NOT have external descriptions by default! You must install description packs or rely on mod authors to use the API to add them! Base + More (English) Base Game (English) An alternative to Wofsauge's External Item Descriptions that supports mo...40.7k downloadsupdated 9 y ago
- Tasty Food Respriteby 76561198408359456A mod that simply resprites hp up food items to be... actually food. Isaac has enough problems to deal with anyways let food not be one of them. New sprites for the following items: • Lunch • Dinner • Dessert • Breakfast • Rotten Meat • A Snack • Midnight Snack • Binge Eater • Supper I know there...40.7k downloadsupdated 5 y ago
- 20/20 but COOLERby 76561198804757721This mod needs UniqueItemsAPI to function!! •20/20 but is cooler and awesome and every character have their own custom glasses!!!! •Pedestal and costume •Maybe in a future work with mod characters like Samael, Mei or the weed baby aka GreenIsaac ====================== UPDATE 10/21/2023: Thanks gu...40.2k downloadsupdated 3 y ago
- Tetrachromacyby GhostTetrachromacy! The loved item from the not so loved mod returns! The item, Tetrachromacy, lets you shoot in all directions! While also adding a splash of color into the game! The item is found in treasure and angel rooms, both in normal and greed mode. Synergises with a buttload of items that inc...40.1k downloadsupdated 9 y ago
- Angel Blade [AB+ ONLY]by micromarioFinally! A purely melee weapon in Isaac! It gives you a suit of armor, and an epic blade to slay your foes. It synergyies with over 60 items, most of which "enchant" the blade, giving it a new and special apperance. *I've update the mod (almost 2 years later)* Issac now continues to fire after pi...39.9k downloadsupdated 8 y ago
- Alt Horsemen (COMPLETE)by hippocrunchyThis mod adds a completely new set of harbingers for the alternate path! Also comes with a unique (stronger) cube of meat variant. Requires Custom Stage API get it -> here ----------------------------------------- Harbinger Hitlist Famine (Downpour/Dross) ✓ War (Mines/Ashpit) ✓ Death (Mausoleum/G...39.7k downloadsupdated 4 mo ago
- Co-op Boss Itemsby ☢ Nato Potato ☢When you play a co-op game using the true co-op mod bosses will spawn items in the corners of the room instead of in the center, each player can only go near one corner so all players get one item each. It also takes into account if you have there's options and can spawn 2 items in each corner of...38.8k downloadsupdated 6 y ago
- Rock Bottom But Reallyby OctotronChanges the Rock Bottom item from Repentance into a... Rock Bottom. It was a meme at first but someone actually wanted a mod so I made it... ...Sorry.38.7k downloadsupdated 5 y ago
- neko sackheadby jevil deltarune (any/all)yooooo neko sackhead? neko sackhead baybee cat sack head UPDATE: Added item sprite and grab bag sprite38.5k downloadsupdated 5 y ago
- Quake Shotby ☢ Nato Potato ☢This mod adds the 'Crown of Stone' item to the game which gives Isaac a new type of weapon, QUAKE SHOT. With this item instead of shooting tears you charge and fire shockwaves that travel across the floor, aside from dealing damage these quakes also break rocks, fill pits, break blue/purple fires...38.4k downloadsupdated 9 mo ago
- (AB+ ONLY) Extra Constellationsby ErflyIt's written in the stars! WILL NOT BE UPDATED FURTHER This is a super old mod, I made it when I was new to modding and am really not interested in updating it at this point, sorry! ======================================================================== MAKE SURE TO DISABLE THE 'ONLY OPHIUCHUS'...38.3k downloadsupdated 10 y ago
- Items In Spawn Repentanceby EpicenterAdds a bunch of items to spawn room for normal runs and treasure rooms for Greed runs. Replacement for similar old mod that does not function anymore. - Works with Repentance - Compatibility with other mods not tested (works with advanced item descriptions though) - May ruin your game experience...38.2k downloadsupdated 5 y ago
- Doki Doki Repentanceby CrashpunkThis is an overhauled version of the original DDLC Isaac Mod for AB+. Current Version: v3.5.2 REPENTOGON is not required but highly recommended! 4 playable characters with unique transformations Unlockable Achievements (REPENTOGON Only) Tainted characters with exclusive Pocket Items 5 Active Item...38.2k downloadsupdated 3 mo ago
- Glareby CodeRedThis mod adds a brand new character: Glare! Glare comes equipped with a sword, which is impaling his head. Instead of firing tears he drops the sword into the ground. When the sword lands, it deals damage in a small area around it, and fires a burst of his tears in every direction. Activating the...38.2k downloadsupdated 5 y ago
- Gnawed Leaf does a JoJo Poseby peasChanges the Gnawed Leaf statue into a JoJo pose, pretty self explanatory. Sorry for leaving a 40 MB gif in the files of this mod.38.1k downloadsupdated 5 y ago
- YSDby 76561198448106326!!!warning!!! This mod modifies the ending after defeating final boss "the Beast". If you have not yet defeated this boss, please disable this mod and experience the correct ending first before enabling it. Added a new character "Ysd" and his tainted version. Ysd: Ysd doesn't need to be unlocked....38.0k downloadsupdated 13 mo ago
- Items start rooms - Repentanceby ApodeusThis mod adds 28 items at each start rooms. Available in Greed Mode, in item rooms only. It's compatible with Repentance.38.0k downloadsupdated 6 y ago
- Heaven's Call [Solar Update](RGON)by UltrinikDO NOT HAVE INSTALLED OLD HEAVEN'S CALL VERSION!!! THIS MOD REQUIRES TO FUNCTION Check Isaac Guru's page for more detailed information Follow Heaven's Call on Twitter Mirror download for manual installation Play Heaven's Call Suika 13 new boss battles await your challenge! 1 FINAL BOSS! 10 Challe...37.8k downloadsupdated 14 mo ago
- Options Respriteby claude27aResprite Option items37.6k downloadsupdated 3 y ago
- [Rep] More Options (1st Treasure room)by ClocksThis is my own version of the concept brought by the "There's Way More Options at the Start" mod, which was a bit buggy and a bit too abusable in my opinion. The options show up in the first treasure room instead of the start room to make it more difficult and to avoid accidental planetarium chan...37.0k downloadsupdated 5 y ago
- Zach [10+ Unlocks]by 26 years of gooning laterZach Death and the dice level all distinctions! Zach is a compulsive gambler - every room he clears grants him a poker chip! He can spend the stack of chips to roll his lucky pair of dice: Snake Eyes. Rolling the dice can grant boons such as stat upgrades, pickups and perks to improve future roll...36.9k downloadsupdated 5 y ago
- Lost and Forgottenby ENFOR!!! Lost and Forgotten requires Stage API to work properly !!! !!! Repentogon is NOT required but it's highly recomended !!! This mod is a Repentance port of the original Lost and Forgotten for Afterbirth+ with double the amount of features, improved art and performance. o Features o 100+ items 2...36.8k downloadsupdated 16 mo ago
- [Rep|AB+] Lilium Dimensionby St. GibonusLilium Dimension is an item that turns you into a medium. Item effects: - enemies have a chance to turn into a ghost after they die. - Ghosts don't get hit, they fight for you for a while then evaporate. - The ghosts damage scale with your damage (they hurt enemies for 1.3x your damage.) Their li...36.4k downloadsupdated 5 y ago
- Lil' Deliriumby AshHes Delirious! A mod created by Scayze with art and idea created by Ashkait (me!) Add a passive item found in angel rooms that will transform into other familiars every 10 seconds, mimicing their behaviour entirely. You could get Lil' Brim and Meatboy, but watch out for Bobs Brain and BBF! Works...36.0k downloadsupdated 10 y ago
- Boss Butch! (13 new bosses)by PixelPlzBoss Butch adds 13 brand new bosses to kick your ass in unique and surprising ways! If that's not enough for you, then you can also test your might in the Boss Butch challenge, featuring all of the new bosses! Also included is a special Boss Butch Bestiary™, where you can learn more about your fa...35.6k downloadsupdated 4 mo ago
- Spinup Diceby widzu95 [⇄]--MIGHT NOT WORK FOR SOME PEOPLE, FIX IS CURRENTLY IN PROGRESS-- Adds a new type of Dice, Spinup Dice! This dice is like Spindown Dice, but instead of rerolling into item with 1 lower ID, it rolls into item with 1 higher ID. Rerolls skips empty IDs and Dad's Note, so you won't land into situation...35.6k downloadsupdated 4 y ago
- Hush Now Drops Eden's Blessingby ErwanHush Now Drops Eden's Blessing You don't have enough reasons to go for Hush? You think it's a waste of time and not rewarding enough? Well, now it's time to destroy him again! With this mod, if you already unlocked the item, Hush now drops the amazing item Eden's Blessing when you kill him! A goo...35.5k downloadsupdated 4 mo ago
- Minecraft-style bombby 76561199060899854I changed the bomb to Minecraft style , I think it's very appropriate. And I didn't change the texture of the props because it might make them hard to recognize. Some of the stickers may not be perfect, if you have any suggestions for improvement, please let me know :) Hope everyone enjoy it.35.3k downloadsupdated 10 mo ago
- ꞈStat Change Commandsꞈby ☢ Nato Potato ☢This mod adds commands to the console that allow you to change your stats on the fly, useful if you're testing things out, or just want to cheat. Just press ~ to open the console and enter in any of the below: Movespeed X Range X Firedelay X (or Tears X if you're using Repentance) Shotspeed X Dam...35.3k downloadsupdated 18 mo ago
- Thought (IN BOOSTER #3)by electoonEDIT: We've made it again! Find it in the game as Angelic Prism! Eclipsed by the moon... Thought is a new orbital that fractures your tears into 4 separate rays! This item syncs with all Technology items (excluding Tech X), Dr. Fetus, Brimstone, and Ipecac! It's available in the Angel and Treasur...35.2k downloadsupdated 10 y ago
- Noah (Playable Character)by 76561199101563685This mod requires Repentogon to work! Click on the Repentogon warning above or visit repentogon.com for further instructions. Noah Noah is a brand new modded character with three soul hearts, low base damage, and a 1.25x tear rate multiplier. Noah is locked in any new save file, but you can unloc...35.1k downloadsupdated 3 mo ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

