The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth pickups mods
Everything filed under pickups by its own author, ordered by how much it is used.
405 pickups mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
405 pickups mods
- Bocchi The Coinsby Teto Pearmonedas personalizadas de bocchi the rock!!! BOCCHI PENNY NIQUEL IKUYO NIJIKA DIME LUCKY RYO BOCCHISAURIO PENNY4.0k downloadsupdated 4 y ago
- Notable mimic chestsby 76561198361835493Chests are now more visible Two kinds of animation (regular and with flat file) Colour does not change when opening a chest For the test: 1) To enable the console, you need to go to this path: C:\Users\******\Documents\My Games\Binding of Isaac Repentance\options.ini and find EnableDebugConsole=0...4.0k downloadsupdated 5 y ago
- The Lighterby MouseThis mod adds a new item into the basement! ~THE LIGHTER~ - On damage Isaac transforms into a living bomb and has 2 seconds to decide where to explode! He also doesn't get damage from the explosion and from the enemies while he is exploding! He deals normal bomb damage (60 DMG) to everything in h...4.0k downloadsupdated 10 y ago
- Amazing Chest Aheadby Iris HeartThis mod aims to meddle a bit with them vanilla chests. Regular chests now have 5% chance to become wooden chests. Golden chests now have 5% chance to become old chests. Red chests now have 25% to drop a cracked key in addition to anything that was inside, and the Red Key is more likely to appear...4.0k downloadsupdated 3 y ago
- Triforce of Greedby certifiableGrimalkinA small mod of three items and one transformation. Was based on a friends idea to make something like Money = Power, but for other pickups. Adds: Power is Power - Damage up + Knockout tears + Damage up for every bomb one has. Wisdom is Power - Range up + Burning tears + Damage up for every key on...3.9k downloadsupdated 10 y ago
- Yankee with no BRIMstoneby MiggliHello! This Mod replaces the Brimstone graphics with Yankee with no BRIM(stone)! It adds a Sound effect and makes Isaac wear the cool hat! The SFX work again now thanks to !3.9k downloadsupdated 5 y ago
- AwfulTweaks [RGON]by Mr. HeadcrabThis mod requires Be sure to follow the full install instructions on repentogon.com Are you sick of the standard, well-thought-out challenge mods out there? Have you found yourself wanting a mod made primarily for the enjoyment of anyone watching you play? This might be the mod for you! This mod...3.9k downloadsupdated 4 mo ago
- Drenched Pennyby MouseThis mod adds a new trinket into the basement! ~DRENCHED PENNY~ - Everytime while Isaac holds this trinket and picks up a penny, 8 tears will shoot in a circular pattern (like Tammy's Head) - The damage of these tears is a addition of 7 to the player's damage. The damage increases by the worth of...3.9k downloadsupdated 9 y ago
- LSD Consumableby ArcticPlease leave a comment, I'd love to know what you think of my first mod! It's acid! Take it and freak out. Think your parents are trying to kill you! This mod adds a consumable with a 1/32 chance to replace cards and runes. Using it will make you see crazy sh*t, man. On top of that, it applies a...3.9k downloadsupdated 9 y ago
- Sad Pickups SFXby SoundbinNow melodic pickups sounds are sad just like our good old friend Isaac :(3.8k downloadsupdated 2 y ago
- Four Souls Troll Bombsby RubySlugTransforms your 2014 troll bombs into the recent Four Souls iteration! Compatible with S-body's Better Bombs, however combining both mods only affects troll bombs naturally spawned by the game (Tower cards, anarchist's cookbook etc. will spawn troll bombs with custom sprites from the better bombs...3.8k downloadsupdated 5 y ago
- Drop Button To Phase Through Pickups [Rework]by 76561199032508689Don't want to accidentally bump into an item or key? Mega chest in the way again? Holding the drop button lets you walk right through pickups. This is my reworked version of It basically works the same as the original mod, but with a few changes: Press 'V' on the keyboard to toggle walk through p...3.8k downloadsupdated 3 y ago
- "Dog covering nose meme" SFXby 76561198324384778Changes the negative sound effect for consuming bad pills, losing on a slot machine or pressing buttons for the semi-popular "dog covering nose meme" audio. I hope you'll like it!3.8k downloadsupdated 4 y ago
- 10 cards packby 7656119880340664810 new cards have appeared in the basement! ·This mod adds 10 new cards with new effects to the game! Cards list: - God card *Effects: It has a 95% chance of giving you a coin and a 5% chance of giving you godhead *Spawn chance: 0.5% - Mirror card *Effects: Changes all your items (like D4) *Spawn...3.8k downloadsupdated 7 y ago
- Antibirth for AB+ (and Repentance)by im_temDo not install this if you want to play Antibirth, go to antibirth dot com instead Antibirth was made by P.E.N.I.S team, not me or even better, get yourself Repentance instead of running this, dammit! ----- Antiborne is now real, even for Afterbirth+ (now also for Repentance!) Let's be honest, yo...3.8k downloadsupdated 4 y ago
- Rosaries Over Coinsby 76561198963408565Change "all" coins with rosaries Changed: All coin trinkets All coin pickups All Slot Machines got rosaries instead of coins A Quarte - Rosary Necklace A Dollar - Heavy Rosary Necklace Wooden Nickel - Wooden Rosar (Changed Kipper's HP temporarily removed)3.7k downloadsupdated 8 mo ago
- The Binding of Pokimon Mystery Dungeon [Afterbith + Edition]by NarxThe Binding Of Pokimon Mystery Dungeon is a mod that turns Isaac's basement into pokemon mystery dungeon world, includes PMD levels, bosses soundtrack sound effects and much more... DOWNLOAD FULL VERSION HERE: mega. nz/file/yhEADZpa#X9R9MN2_tNITsbixkOxlmknccSU1cBjsD5GEUmaVbwI FEATURES: -Playable...3.6k downloadsupdated 6 y ago
- UI Hearts Mod Compatibilityby 76561199023532519This mod re-sprites the UIs and sprites of custom hearts of many popular mods to match the ones from UI Hearts by ALADAR It currently supports: Fiend Folio Repentance Plus! Arachna Extra-Scared Scared Hearts More Minisaacs Deliverance Restored Hearts (Illusion Hearts by Akad also supported) Angel...3.6k downloadsupdated 3 mo ago
- Coupon Bookby MouseThis mod adds a new trinket into the basement! ~ COUPON BOOK ~ - The higher your luck the higher the chance to put items on sale! - If held with Steam Sale item has a chance to become free of charge - Chance with 0 luck is 1/6 and every luck up adds increases the chance by .5 (1 luck = 1/5.5) Red...3.5k downloadsupdated 9 y ago
- Distinct Sticky Nickelby kittenchillyMakes Sticky Nickels more visually distinct from regular nickels, and gives them a pretty nice sticky effect too.3.5k downloadsupdated 5 y ago
- Luck-based Coinsby MouseThis mod lets more valuable coins appear based off your luck stat. -1 luck = normal chance 0 = 1% chance 1 = 1% chance 2 = 2% chance ... The lucky ones get richer....3.5k downloadsupdated 10 y ago
405 pickups mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

