Mods / Pickups

• !!Rebirth Items Vectorized ! No HUD [OBSELETE]by EMORYRebirth Vectorized! replaces all item sprites with rasterized vector art similar to that of the original Flash game, but with vibrancy of Rebirth's sprites. New art for all of Isaac's items! Check out www.cormacillustrated.com/ for a gallery of all the artwork Modded items may be invisible and ne...5.2k downloadsupdated 4 y ago
• RRunic Tabletby 76561199101563685Runic Tablet This mod adds a new item to the Shop and Curse Room pool: The Runic Tablet. Runic Tablet spawns a random rune when picked up, increases the chance of runes appearing as room-clear rewards, and it adds an extra effect to every Rune and Soul Stone. Rune Buffs This mod features addition...5.2k downloadsupdated 2 mo ago
• GGold Paintby Griffinbob1Gold Paint is a trinket that doubles the chance for a golden key, bomb, or heart to spawn. If you have any comments or adjustment suggestions feel free to leave them down in the comments below.5.1k downloadsupdated 9 y ago
• TTough Gloveby NickSquigglesTired of running into Mimic Chests in a hurry? Worry no further! Holding the Tough Glove trinket means you won't take damage from Spiked & Mimic Chests :D All feedback welcome5.0k downloadsupdated 10 y ago
• TTainted Cain holds Lucky Toe and Justice!by raineAs the title states, this is a simple mod that gives Tainted Cain the Lucky Toe trinket and the VIII - Justice tarot card! Despite his unique crafting mechanic, T. Cain to me felt somewhat underpowered compared to the other tainted characters. This mod remedies that by helping him out with a tiny...5.0k downloadsupdated 5 y ago
• NNeko hearts~by 76561199024203068Replaced textures: Hearts on the floor Hearts in the shop Hearts in Satan's room From beggars and gambling machines Blood machine Also updated the sound of picking up each type of hearts and some animations.5.0k downloadsupdated 3 y ago
• ББро ты умрёшь и т.дby 76561199115858749Заменяет некрономикон на фото "бро ты умрёшь и т.д" и пробуждённый некрономиком на "бро ты воскреснешь и т.д" p.s мой первый мод поэтому строго не судите и если нашли баги то пишите Спасибо Пепре за то что показал этот мод в своём видео!5.0k downloadsupdated 13 mo ago
• CCricket Transformationby MacVilleLPWith that Mod you will geht the Crickt Transformation What is new in this Version (v1.2) - Update LUA that previous Customes will remove when you get Cricket. What is new in this Version (v1.1) - Update all Sprides (now everything is Cricket) - Updated Code - Create Code for further Changes With...5.0k downloadsupdated 10 y ago
• OOld Restockby NeylickPrices will not increase after a shop restock. Compatible with and4.9k downloadsupdated 2 y ago
• Mmenacing haunted chestby Boosiusadds the funny jojo menacing to haunted chests to make them cooler but also easier to spot. (this is for ruining my tainted lost run you ass)4.9k downloadsupdated 5 y ago
• MMinecraft Bedsby 76561198798504070Replaces the beds that spawn in Isaac's room with the bed from minecraft. clean rooms have a red bed, dirty rooms have a white bed, and Mom's room has a purple bed.4.9k downloadsupdated 3 y ago
• PPulled Teeth [AB+ Ver.]by KrowskiPulled Teeth for Repentance now available! Have you ever thought to yourself, "This game has too many teeth?" Of course you have! And now the solution is finally here! Pulled Teeth removes any trace of teeth from the game for all of your gummy, detoothed needs! After 10 14 too many months of hard...4.9k downloadsupdated 5 y ago
• CChamuelby 76561198858875349Tear your heart out with Chamuel, a character that utilizes them for combat! 21+ unlocks to uncover! (28 with Epiphany) All collected hearts orbit around him instead of being added to the HP bar Orbiting hearts are destroyed on contact with monsters, damaging Chamuel Arrow keys = attack Every hea...4.8k downloadsupdated 4 y ago
• HHorsier Horse Pills™by SprSnpr_Say 'neigh' to boring horse pills! I've spruced up the horse pill sound effect with some equine nonsense.4.8k downloadsupdated 5 y ago
• CCoins are Rotating Cheeseby 🎮-_MAX_-🎮This mod just replaces all coins with rotating cheese. It's time to cheese!4.7k downloadsupdated 16 mo ago
• GGunpowder Pillby ☢ Nato Potato ☢The gunpowder pill grants the pyromaniac effect for the current room and causes an explosion around the player. Use it in a pinch to kill the enemies around you and heal 1 heart, or when fighting against an enemy that uses explosions like Sloth, or just to hit a tinted rock or to spend a bomb or...4.6k downloadsupdated 4 y ago
• SSacredDreams EID汉化by 76561199253021281SacredDreams的EID汉化模组 汉化作者：B站@青灼QWQ4.6k downloadsupdated 2 y ago
• ((OUTDATED DO NOT USE) Another Graphical Overhaulby RareFor years, there have been things that have bothered me about Isaac. It's mostly small stuff, but it's there, and I've finally decided to go out and fix it. Here is the result of my work, as well as the work of many others (all used with permission), combined into one convient mod. -Screenshots a...4.6k downloadsupdated 9 y ago
• DDLCby agilebananaDLC More Content... A passive item that spawns extra shop pickups. The further stage you are on, the more pickups that spawn.4.6k downloadsupdated 10 y ago
• TTung Tung Devil replaces Satanby 76561199311872895dont worry hes with tung now TUNG TUNG DEVIL REPLACES SATAN only replaces statue, not boss sorry not sorry maybe if this gets on front page of workshop ill consider it winkwinkwinkwinkwink tung tung god here:4.6k downloadsupdated 7 mo ago
• [[REP/+] Quick Start 2.0by NightWareMakes sure your first floor Treasure Room item is atleast of Quality 3 and up. Works with Repentance(+) DLC. Works on Greed(ier) Mode (only 1 Treasure Room will re-roll). Repentogon is not required, but I do recommend using it.4.6k downloadsupdated 14 mo ago
• CCard Collector - Playable characterby ☢ Nato Potato ☢The Card Collector starts with Card Printer, Deck of Cards, Starter Deck, Ace of Spaces and 20/20, they get a free active item card in the starting room and treasure room each floor and they get 1 active item charge whenever they use up a card. However they won't take any active items aside from...4.5k downloadsupdated 4 y ago
• TThe Big Cookieby 76561198390663903Introducing the big cookie, an item based off of cookie clicker! Made so i could learn how to code isaac more! This mod adds one active item which every few uses, will give you up to 7 unique cookies*, each with their own effects! (And news tickers!) After all cookie items have been given, it wil...4.5k downloadsupdated 4 y ago
• EEasy Modeby WishfulThis Mod "Easy Mode" Changes Every Characters Health To Full (Weather It Be Black Hearts Or Red Hearts). It Also Gives Them 99 Keys, Bombs & Coins. *This Mod Does Not Change The Damage Of Any Character.*4.5k downloadsupdated 10 y ago
• IIsaac Ukranian 0.2vby DemabelThe Binding of Isaac Українською 1.0 v ВАЖЛИВА ІНФОРМАЦІЯ!! Дана українізація адаптована під англомовну версію гри, перед завантаженням перемкніть на неї, якщо використовуєте іншу. Крім того не забувайте щоб отримувати оновлення, вам треба повністю видалити папку з модом, зайти в гру. Скачати йог...4.4k downloadsupdated 3 y ago
• [[REP] Double Soul Heartsby 76561198834414803Double Soul Hearts What's This? As you well know there are many variants of hearts; Red Hearts, Soul Hearts, Eternal Hearts etc. One of them is 'Double Red Heart'. So why don't make a double versions of other variants! And that's it. Update #1 New Double Hearts variant! Double Bone Hearts! Now wh...4.4k downloadsupdated 5 y ago
• CCurse Of Blind To Catby 76561198359088761Changes "?" to this cat.4.4k downloadsupdated 4 y ago
• [[REP] Lifebar - HUD Reskin mod (and more!)by peasPrettify your HUD! This mod reskins various HUD elements to look more visually appealing, taking inspiration from the flash game's unique art style. This mod also reskins select pickups and consumables when dropped on the floor, and whatever else I felt like remaking at the time. Expect updates w...4.4k downloadsupdated 5 y ago
• [[REUPLOAD] Aladar's UI Hearts Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...4.4k downloadsupdated 17 mo ago
• [[REP+] Remove useless heartsby 76561199164471930Useless hearts will be replaced by soul hearts Blue Baby, Tainted Blue Baby, Tainted Judas and Tainted Forgotten no longer generate red hearts. The Lost and Tainted Lost will replace hearts with coins. Compatible with co-op, characters have priority in converting hearts to make it playable. One c...4.4k downloadsupdated 9 mo ago
• SSussy Hearts [OLD]by 76561198845689038A sussy mod where our hearts, animations and an achievement (scared heart) become the characters of among us. Enjoy.4.3k downloadsupdated 3 y ago
• TThe Binding Of Cat Nuoby 76561198431463778Catnuo is a game steamer in bilibili, and you can follow her with the link Mod Description: 1.Two playable Characters Catnuo and Tainted Catnuo Catnuo: (1)start with D6 and 3 bombs (2)Damage Rate = 1.05, Luck = 1 (3)BirthRight Effect: Angel room opening rate increased by 30% Defeating the angel i...4.3k downloadsupdated 3 y ago
• DD666by micromarioDescription: Reroll your soul Itempools: Treasure and devil Effects: (Active) If you have red health, the item takes two hearts away and gives you a random devil deal item If you have soul health, the item takes three hearts away and gives you a random devil deal item If you don't have health, th...4.3k downloadsupdated 10 y ago
• [[REP+] Always Restockby 76561199164471930Now there is always a restock machine in the shop This mod ensures that you will always find a restock machine in shops, both in normal mode and in Greed Mode. The restock machine is automatically generated in all shops and adapts by adjusting its position when you play as the Tainted Keeper.4.3k downloadsupdated 9 mo ago
• MMajorasMaskModby GiurassicEver wanted to feel protected ? Ever wanted to feel powerful ? Well now you can ! The ALL NEW Majoras Mask will give you everything you need (if all you need is a +5 damage up and 2 black hearts) Soon to come : Different tears ANIMATIONS MORE items Suggestions are welcomed :D4.2k downloadsupdated 10 y ago
• NNo Stickies on Tainted Keeperby DoggersI think Tainted Keeper players can relate to this scenario. You are playing Greedier mode. You are left with a single coin heart, because game has decided to give you a bullet hell. You have killed a little poor Gaper which has dropped a Nickel! Time to pick it up. Wait, what's that? It's glued t...4.2k downloadsupdated 3 y ago
• DDecent Startby 76561199481423011There will spawn 1 coin 1 bomb 1 key 1 wooden chest in the starting room. 初始房间会生成1硬币，1炸弹，1钥匙和1木箱子。4.2k downloadsupdated 20 mo ago
• TTerraria teksturaby AsukaМод меняет предметы Айзека на предметы террарии The mod changes Isaac's items to terraria items The mod changes 176 items Over 56 familiars Over 240 costumes (from over 50 different items) 6 transformations Keys, bombs, coins All hearts 15 trinket Redrawn all tarot cards and inverted tarot cards...4.2k downloadsupdated 3 y ago
• IItems Reforged [Afterbirth+]by KaliItems Reforged! This mod aims to rebalance and tweak items that would otherwise be detrimental to a run, while remaining faithful to the vanilla experience. Supports External Item Descriptions! Supports Mod Config Menu! Supports Revelations! Supports Fiend Folio! & More! All changes are configura...4.2k downloadsupdated 6 y ago
• SSocial Anxietyby Exudias*Passive item *You feel endangered! (You gain damage proportionate to the amount of enemies in the room you are in) This is my first passive item I've added to the game. Awesome people: Lytebringr, Eufuu and CustomPhase See it in action here:4.2k downloadsupdated 10 y ago
• BBaby Plum Trophyby SprSnpr_Plum Trophy. Nuff said. This mod was made by request4.1k downloadsupdated 5 y ago
• SSyringes! A New Consumable [Afterbirth+ Only]by AgentCuccoA brand new type of consumable! - Syringes behave similar to pills, they give temporary buffs or debuffs to the players, and they are undiscovered until used for the first time. - At the beginning of a run, a pool of 13 random syringes is determined for the rest of the run. - Syringes have a 33%...4.1k downloadsupdated 6 y ago
• BBad to the bone (heart)by 76561199085805882*Insert riff here*4.1k downloadsupdated 4 y ago
• TTainted Cain Can Duplicate Pickupsby GuilhermeTainted Cain is a fun character, but since it's recipes are not fixed anymore I think that his power decreased a lot, so I decided to buff him. unlike another mods that buffs characters giving items, trinkets or cards I decided to make a small mechanic for tainted cain, when you pick a pickup or...4.1k downloadsupdated 5 y ago
• AAGF's Heart Respriteby 76561199447159173잼게 즐겨주시면 감사하겟습니다 (_ _)4.1k downloadsupdated 14 mo ago
• CChallenge: The Basement Rouletteby Red.16This mod features a unique strategetic challenge, inspired by a videogame that uses shotgun to play Russian roulette. Also comes with 9 new pocket items, each has their own tricks in and outside the challenge. Have fun!4.0k downloadsupdated 17 mo ago
• FFiend Folio [RUS]by Dick NukemFiend Folio Изменения внесены только в части переведенных строк для мода EID (External Item Descriptions) Как установить: 1. Скачать все другие необходимые моды, а именно: Fiend Folio: Reheated - 500 New Monsters! Custom Stage API External Item Descriptions - настроить на русский язык 2. Установи...4.0k downloadsupdated 3 y ago
• BBlåhaj bedby 76561199117065460All beds are replaced with beds with IKEA plush sharks in them! I like blahaj :34.0k downloadsupdated 13 mo ago

405 pickups mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.