Mods / Enemies

• UUMA overhaul [DISCONTINUED]by Greenagon! If you want only specific things from this mod please download it and make your own smaller packs so I don't have to flood the workshop with them ! UMA overhaul is a ( work in progress ) graphical mod that changes a few sprites of the game. I personally like these custom textures more but due t...9.2k downloadsupdated 8 y ago
• NNeko Boom Flies (NOW WITH RED FLIES!)by 76561198842354630MAKES THE BOOM FLIES LITTLE KITTY CATS LITTLE GUYS LITTLE LITTLE GUYS CUTE LITTY KITTY CATS!!!!!!!!!!!!!!!!!!!!!!!!!!! UPDATED AND NOW INCLUDES CHAMPIONS + RED ONES9.1k downloadsupdated 4 y ago
• EEiballs' Hush Respriteby the loathsome gamermy very first mod includes brand spankin new sprites for: hush boss portrait both phases of hush blue gapers blue conjoined fatties blue boils hush flies hushy enjoy check out my other resprite mod here:9.1k downloadsupdated 4 y ago
• Ppochita modby MelanChanges the sprites for "Blood Puppy" item into the character Pochita from the manga "Chainsaw Man".9.0k downloadsupdated 22 mo ago
• PPatrick Gluttonyby SchlomannChanges Gluttony into Patrick star :)9.0k downloadsupdated 9 mo ago
• GGhost Pepper Rework!by Mr. HeadcrabThe beloved Ghost Pepper is looking hotter than ever! This all new Ghost Pepper shoots out the same white flame you can find in Downpour, one that will exorcise any monster in it's way! These disembodied souls are far weaker than the hosts they come from, and will prioritize getting back into the...9.0k downloadsupdated 3 y ago
• Tthe binding of maggy's toy box and WOB isaac's secret stashby 76561199032451894BUG FIX: 超级撒旦和鲍勃的烂头动画修复！ MegaSatan and Bobsrottenhead Animation fix! 炸弹乞丐被炸不出炸弹修复！ Fixed the Bomb Bum not dropping an insta-exploding bomb when blown up！ 究极傲慢宝宝瞎几把乱闪修复！ Fixed the Ultra Pride Baby incorrect flashing animation! 个人整合包，非原作者，模组来源： maggy's toy box maggy's toy box reborn WOB isaac's sec...8.9k downloadsupdated 12 d ago
• TThe Binding of Isaac: Eternal Youthby snooch"The Binding of Isaac : Eternal Youth" Is planned to be a huge content pack for the game! This is a mod made from a small bunch of people who share similar passion for the game. Current Content ============== 10 Items Abomination Baby - A familar that likes to reward you with a troll bomb at the...8.9k downloadsupdated 10 y ago
• RRooms and Roams (700+ rooms)by MarbleTearsHello, welcome to Rooms & Roams!! an expansive mod for more adventures This mod add Adds: 100+ rooms for every chapter (basement, caves and depths) 50 + rooms for every alts (burning basement, cellar, etc) 50 + rooms for every alt2 chapter (downpour, mines, etc) + 200 special rooms (planetariums,...8.9k downloadsupdated 14 mo ago
• MMorbius Fat Batby HolyCrossThe morbius fever is sweeping the basement! ⣾⣿⡆⣴⣿⡇⢰⣿⣿⣦⢰⣿⠿⣷⡄⣾⣿⣿⣦⢾⣿⡷⢰⣿⣆⣿⡇⣾⠀ ⠀ ⢿⡿⣷⣿⣿⡇⣾⡏⢹⣿⢸⣿⣄⣾⠇⣿⣇⣿⠟⠈⣿⠀⢸⣿⢿⣿⡇⠉⠀ ⢸⡇⢹⡇⢿⡇⢻⣿⣼⡏⠈⣿⠛⣿⡄⣿⣏⣿⡆⢀⣿⡀⢸⣿⠘⢿⡇⠀⠀ ⠀ ⠘⠃⠈⠀⠘⠁⠈⠛⠋⠀⠀⠙⠀⠘⠁⠘⠛⠋⠀⠘⠛⠁⠈⠃⠀⠘⠁⠀⠀ ⠄⠄⠄⠄⠄⠄⠄⠄⠄⠄⠄⠄⠈⢻⣿⣿⣿⣿⣿⣿⣿⣿⣿⢿⣿⠁⠄⠄⠄ ⠄⠄⠄⠄⠄⠄⠄⠄⠄🔴⠄⠄⠂⠈⠛⣿⣿⠿⠿⠋⠉⠁⠄⠙⠛⠄⠄⠄ ⠄⠄⠄⠄⠄⠄⢠⣦⣤⣤⣴⣶⡤⠤⣶⣾⣿⣤⣄⡀🔴⡁⠠⣾⡀⠄⠄⠄ ⠄⠄⠄⠄⠄⢰⣿⣿⣿⣿⣿⢿⠄⢀⢼⣿⣿⣿⣿⣿⣾⣋⣁⣸⣿⠃⠄⠄⠄ ⠄⠄⠄⠄⠄⠄⠍⣿⣿⠟⠁...8.8k downloadsupdated 4 y ago
• GGuwah Greaturesby GuwahavelThis mod is for Repentance Have you ever felt a desire for something more to your floors? More intrigue? More greatures? More challenge? Then this mod is for you! This mod adds: -17 new enemies to test your mettle! -Over 1500 new rooms, spread across every floor in the game! -2 new items! -Surpri...8.7k downloadsupdated 4 y ago
• TThe Binding of the Spire Englishby 76561198355620741这是英文版本 中文版请在创意工坊找同名MOD tips:PC Only Slay the Spire MOD 34 new items! 44 new cards! How to Play： WSAD Move Mouse Left : Attack Mouse Right : Use Card/Click Button/ KeyBoard :1/2/3/4/5/6 Use Card turn off enemy'smark:input "target" in console right click to pick starting bonus right click to pick s...8.7k downloadsupdated 8 y ago
• RRepentance Negative-by 76561199094088506We present to you a mod that is not of the best quality, but with interesting jokes! Also, dig through the mod files, you never know what might be hiding there... Repentogon required! Adds 2 new character! Adds 30+ new items! Adds 5+ new trinkets Adds 1 new card, pill and new pickups and machine...8.7k downloadsupdated 8 mo ago
• TThe Cursed and Brokenhearted - "I Never Forgot You"by 76561198813288416Notice I will not update this any further, I just readded it so people can play it Prerequisites for the best experience StageAPI - For the new bosses and such MMC - For the new music in the game! MinimapAPI Immortal Hearts from Team Compliance - For easier new personality unlock! EID - descripti...8.6k downloadsupdated 3 y ago
• SSpeed, I need this ticking spider!!..by 76561199658847884Replaces ticking spiders with the "Speed, I need this" meme.8.6k downloadsupdated 10 mo ago
• FFace for Poky Familyby 76561199017419812Did you find it strange for pokies and slides to recognize players without eyes? This mode adds faces to monsters in the Poky family! (not for grudges!)8.5k downloadsupdated 6 y ago
• [[Ab+ Only] Complete Eternal Edition+by GuilhermeTHIS MOD IS OUTDATED, Click Here FOR THE REPENTANCE VERSION This mod adds a new champion variant for almost all monsters and for all bosses, all based on the classic game. Eternal enemies are tougher and haves new mechanics, with a small chance of dropping a reward. ATTENTION • Incompatible with:...8.5k downloadsupdated 4 y ago
• YYo Mama's Shadowby HazicaReplaces Mother's Shadow with that Brody guy from Yo Mama, complete with new sounds and chase theme. Made as a joke for a friend group but I figured I'd upload it. Intro will be longer than usual so don't use the mod if you're speedrunning, or something. note: im not updating the video, so its ou...8.4k downloadsupdated 5 y ago
• NNeko Kinetiby 76561198811060732As per request, a new addition to the neko family, the annoying, but now adorable bane of every Mausoleum run, kineti. What other monsters should be made into their cat / neko versions?8.4k downloadsupdated 5 y ago
• FFaith's Rewardby DaGammlaDo you have a bad Computer? Do the fireworks produce lag? Just press "F1" and you're save! CAUTION ! This mod is possibly not compatible with others but Works perfectly with True Co-op Content : --Dynamic Boss drops-- Bosses have a chance to spawn Boss specific items like Mask of Infamy -> Isaac'...8.3k downloadsupdated 8 y ago
• AAlt Path + Mother in Greed Mode!by 76561199034036813With the 1 year anniversary of Planetariums in Greed Mode coming up, I knew I had to return to my roots and make another greed mode mod. So, I present to you: The Alt Path in Greed Mode! Yes, I know this has been done before (twice in fact) but the original mod had 3 main problems that this mod f...8.3k downloadsupdated 4 y ago
• AAntibirth Bishops Altby kittenchillyAnother Antibirth Bishops mod that makes it so the Antibirth Bishop sprites are used only in Mausoluem while the normal Bishop sprites are used everywhere else (i.e. the cathedral). Allows for the best of both worlds, as well as better fitting the color scheme of each stage.8.2k downloadsupdated 5 y ago
• Kknight respritesby 76561198876704734shows the knight sprites some love commissions open8.1k downloadsupdated 3 y ago
• NNeko Hostsby 76561198811060732A new addition to the neko family, the Host family, testing our patience as we wait for them to emerge to shoot us, now cute, more bearable, and if we have got to wait forever, at least they're easier on the eyes. What other monsters would you like to see made into neko versions?8.1k downloadsupdated 21 mo ago
• MMixed Boss Collection Part 1by GuilhermeThis mod is a pack of all my boss mods, does to limitations of how many values a mod can save then It doesn't contain all the bosses, CLICK HERE for the part 2 of the mod and HERE for the part 3 of the mod it also features it's own menu config to change which bosses do you want and which ones wit...8.1k downloadsupdated 3 mo ago
• TThe Binding of Brazil (AB+)by TCDubs✎ 𝗥𝗲𝗽𝗲𝗻𝘁𝗮𝗻𝗰𝗲: --------------- A Tradução Brasileira de "The Binding of Isaac: Afterbirth +" ~Todos os Itens e Suas Próprias Descrições ~Pílulas, Cartas, Runas e Suas Descrições ~Alguns Nomes de Bosses ~Os Desafios ~O Bestiário ~Interface ~Todas as Conquistas ~Booster Pack 1,2,3,4 e 5 ~Andares ~ S...8.0k downloadsupdated 8 y ago
• MMom's ban listby ☢ Nato Potato ☢Mom's ban list lets you pick and choose which monsters you don't want in your game. There are mods out there to remove this monster, remove that monster, remove portals, remove stoneys, remove hosts, etc, but why have several mods when one mod can do it all? With mom's ban list you have a fully c...7.8k downloadsupdated 11 mo ago
• Fflash angelsby 76561198339469043mod that makes angels look much better if you played flash isaac 80 years ago7.8k downloadsupdated 5 mo ago
• Tthe binding of ICGby 御坂14144号WHAT?? UPDATED?? I thought the author was missing in Bermuda or somewhere?! OKOK, the REP update finally come, which fixed most of bugs and made some balance adjustment. ☆ 2 New Characters！ ICG A magical agent who specializes in manipulating rocket-propelled dolls(WTF)/b] · Starts with: - ICG Pro...7.7k downloadsupdated 5 y ago
• CCobson (Beast resprite)by 76561198338773226HWABAG Bone chilling, spine tingling, genre redefining, slow-burn resprite mod that will change The Beast with Cobson. no 'p embedded.7.7k downloadsupdated 3 y ago
• [[Ab+ Only] Monsters Eternal Edition+by GuilhermeTHIS MOD IS OUTDATED, Click Here FOR THE REPENTANCE VERSION This mod adds a new champion variant for almost all monsters, all based on the classic game. Eternal monsters are tougher and haves new mechanics, with a small chance of dropping a reward. ATTENTION • This mod is included in Complete Ete...7.6k downloadsupdated 4 y ago
• LLeviticus Scrollby MerloMany people on reddit have amazing ideas, but can't code them. I, on the other hand have zero ideas, but could code them all. Enter the Reddit's Community Mods Project, where I'll go and find the best ideas from the community, and bring them to life! Check out the full Community Mods Collection o...7.6k downloadsupdated 9 y ago
• NNecrocyst Bossby GuilhermeBlastocyst went to corpse and rotted with the rest of the floor, now you can find it at the boss room of the corpse I. unlike the other bosses that I made, this one don't drop any item because this boss is not from another game or a reference to another game Custom Stage API is required to make t...7.6k downloadsupdated 3 y ago
• DDucky Tube Zombie instead of Deep Gaperby 76561198823663354A mod that replaces Deep Gaper with Ducky Tube Zombie from Plants vs Zombies 1.7.5k downloadsupdated 3 y ago
• BBest Isaac Musicby 76561199030889749Isaac has a lot of pretty good music of various composers, why not extract the best of the most of them??? Like other the music mods, this one replaces almost all Afterbirth/Repentance music tracks for others than I think are better, there are some compositions of DannyB (Flash Isaac), Mudeth (An...7.4k downloadsupdated 3 y ago
• NNeko Colostomiaby transgirlcathyYou knew this was coming. Credit to The Binding Of Isaac discord for telling me to do this. Also credit to my girlfriend for telling me to make the poop bombs have ears. I didn't do that but it was a good idea.7.4k downloadsupdated 5 y ago
• SShe Got An Educationby OctotronChanges the Siren to have some nice glasses and a suit because she got an education. Isn't that pleasant?7.4k downloadsupdated 5 y ago
• DDemoman Squirtsby 76561198866871514Changes the squirt and gurdy noises to demoman screaming. Not much else to say. 2.0 Adds 4 new sounds for your ear splitting enjoyment. Known Issues: - There is a bug where it breaks mods that change Isaac's parents arguing into something different. I am away that is has something to do with soun...7.4k downloadsupdated 18 mo ago
• WWhiteNight Dogmaby 76561198365949909Changes Dogma to WhiteNight Aleph Abnormality from games Lobotomy Corporation and Library of Ruina Features: - WhiteNight as Dogma - New music - New sound effects - Styled visual effects of second phase 🔑🌙 Project Moon7.4k downloadsupdated 7 mo ago
• AAbortionbirth Revelations Compatibilityby NarilliaIf you're one of the lunatics who plays Revelations's Glacier, but wish you could still play the far superior Northern Glacier from Abortionbirth, this is the mod for you! Patches a compatibility issue in Abortionbirth Pack 2: The Heckoning, to allow playing inferior mods alongside it. Also adds...7.4k downloadsupdated 9 y ago
• NNeko Angelic Babyby 76561198811060732A new addition to the neko family, the annoying but now adorable baby, angelic baby and small angelic baby. What other monsters should be made into neko versions?7.3k downloadsupdated 5 y ago
• DDark Esau YOUR TAKING TOO LONGby OmasumiYOUR TAKING TOO LONG. A simple mod that replaces Dark Esau with that fucked up Dark Pumpkin thing from Jackenstein's fight in Deltarune Chapter 4.7.3k downloadsupdated 17 mo ago
• [[Rep] Fox's Champion respritesby FoxenterteinmentA mod created to enrich the visuals of the game in the form of changing the version of the champion mobs to make them look unique. While only classic mobs have been made, an update with monsters from Rebirth is possible in the future. Enjoy, write reviews and point out bugs! ---------------------...7.2k downloadsupdated 5 y ago
• DDelirious Voidby ink toodlesAppearantly people still care so: 1:This mod doesn't work 2:I made a 2.0 version that also doesn't work 3:This mod wont get fixed. I'm sorry. Somewhat sorry. This mod changes every enemy in the void to look like Delirium. All of them. Because, let's be real: The Void is boring. It is empty and no...7.2k downloadsupdated 10 y ago
• DDeep laboratories (AFTERBIRTH PLUS VERSION)by Mogumi-------------------------------------------------------------------------- DEEP LABORATORIES FOR REPENTANCE IS OUT! -------------------------------------------------------------------------- IMPORTANT! Don't force this mod in Repentace! the new DLC changed a lot of sprites and how things work in...7.2k downloadsupdated 6 y ago
• Ggrub respriteby 76561198876704734resprites gruns a bit to look a bit fancier commissions still open7.2k downloadsupdated 3 y ago
• LLuncheon (Tapeworm boss)by MsGummyLuncheon is a new boss inspired from the mechanics of Tapeworm, a board game by Edmund McMillen! Rather than directly attacking the player, Luncheon will throw up his insides which are swarming with wriggling tapeworms, who each attack differently depending on their segments. (Requires StageAPI)...7.1k downloadsupdated 6 y ago
• TTophat needlesby cozyrazuinspiration: my first mod, enjoy...7.1k downloadsupdated 5 y ago

359 enemies mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.