The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth enemies mods
Everything filed under enemies by its own author, ordered by how much it is used.
359 enemies mods, most downloaded first · newest update 26 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
359 enemies mods
- More Diabolical Mega Troll Bombsby 76561198876704734reskins megatroll bombs to look way scarier. boo!12.2k downloadsupdated 4 y ago
- Hopping Cat as Hopper Enemyby peakReplaces the Hopper and Champion Hopper enemies with a Hopping Cat. There may be clipping issues due to this being my first mod but I'm too silly to care. Enjoy the hopping.12.2k downloadsupdated 3 y ago
- Meeps' Monster Respritesby 76561199000831540Meeps' Monster Resprites is a resprite mod (Duh) that aims to overhaul the game's enemies to the much higher quality repentance style, while simultaneously overhauling the game's more bland enemy designs to add a bit more spice and flair. Additionally, a bunch of enemy animations have been change...12.2k downloadsupdated 3 mo ago
- Hp Bar For Enemies (REWORK)by PxntxrezThis is a rework of original HP Bars For Enemies mod by Pxntxrez and JaRo7126 with bug fixes and even more functionality! FEATURES This mod tries to enchance the old Spider Mod hp bar and add something new. This includes: -Added Settings -Showing names of every enemy in the game -2 new types of H...12.1k downloadsupdated 20 mo ago
- The Binding of Steve (Rep. version) : Minecraft Crossoverby Ly FechaIf you like my work, please consider clicking on the like, favorite or even reward button. THIS IS THE REPENTANCE VERSION. Afterbirth+ version : Warning : Due to game and api instability, sounds and some items have been removed temporarly. They will probably be added back after some Repentance up...11.8k downloadsupdated 4 y ago
- Repentance Boss Champions CONTINUEDby kittenchillyThis mod requires REPENTOGON to work! The original mod now ported to REPENTOGON for bug fixes and better mod compatibility! Perhaps even more in the future...? This mod adds 36 new champion variants to the many bosses added in Repentance. These champions seek to emulate the vanilla game - keeping...11.5k downloadsupdated 20 mo ago
- Globin Gooby KoroaTurns Isaac into a glob of goo upon death! This passive item allows Isaac to transform into a glob of goo upon taking lethal damage. If he takes no damage for a short time, he will reform with a half heart of health; synergizes with most upon-damage items. This item is found in the treasure room...11.4k downloadsupdated 9 y ago
- ModJam Vol. 2 (14+ New Characters!)by 76561199208948209REPENTOGON+ IS REQUIRED! You know the drill, download Repentogon+ here! ModJam Vol. 2 focuses on CHARACTERS, rather than items! We present a whopping 14(?) characters, 7 normal characters and 7 tainted characters. Each team had to make a normal character over the span a few weeks, and then was gi...11.2k downloadsupdated 2 mo ago
- Dumplings!by cr24This mod re-adds all 3 Dumpling enemies from Antibirth, adds 2 all-new Dumpling variants, as well as 2000+ rooms containing them mixed throughout several chapters, with a handful of rooms being some of the original Antibirth rooms. The sprites have been slightly touched up and the original champi...11.2k downloadsupdated 3 y ago
- Angel Drop Items Remakeby RudyA remake of the original Angel Drop Items mod, with new features, bug fixes, rebalance and support in the current game version. Were you ever annoyed that after getting both key pieces fighting both Uriel and Gabriel was entirely pointless? Have you never gotten lucky to get the Filigree Feather...11.1k downloadsupdated 10 d ago
- salvationby XtrikeThe Binding of Isaac: Salvation Salvation or Repented characters is a mod that aims to be an alternative of the tainted characters but instead of getting more broken they become more innocent. So far we have 1/17 Characters Completed, being Azazel For each character there is atleast 9 unlocks as...11.1k downloadsupdated 2 y ago
- Gehenna Visual Tweaksby GuwahavelThis mod adds the following visual changes: -The Lil' Portal enemy (and all of its related visual effects) have a red coloration on the Gehenna floor -Morningstars have a 50% chance to spawn with the their unused alt-skin -Morningstars and Maze Roamers have Champion spritesheets -Some of the Tele...10.9k downloadsupdated 5 y ago
- Saul's Goodman Emergency contactby Насрать в тайкусLow effort mod made for fun Features: Emergency contact sfx changed to intro music from Better Call Saul Changed sprite of Emergency contact to Saul's visit card Changed Mom's hand sprite to Saul's face10.9k downloadsupdated 4 y ago
- (AB+) Genesis+ Revivedby BroskiPlays on ROG Ally1.2 BUGFIXES + 1 NEW ITEM ----- Fixed Trapdoor appearing in Catacombs / Caves Fixed Rune not able to be picked up Fixed Boss Room related Bugs Fixed all stuff related to Catacombs Disabled Stagesapi Added 1 new Item: Too Much Water! Enjoy the update and be sure to send me any bug reports :) GENES...10.8k downloadsupdated 9 y ago
- [Rep] The Binding of Isaac: Benevolenceby OliveRiderThe Binding of Isaac: Benevolence Features: - 2 Characters - 60+ Items - 6 Trinkets - 400+ Rooms - 2 Monsters - Monster and boss tweaks - Item tweaks Planned features: - 2 MORE characters - 40+ MORE items - 15+ MORE trinkets - 1200+ MORE rooms - MORE enemies and bosses - More alt floors - MORE it...10.8k downloadsupdated 15 d ago
- Rock angelby 76561199037324892Rock moment it was a very stupid idea10.7k downloadsupdated 5 y ago
- Apocrypha: On The Rocksby 『Sora』Apocrypha On The Rocks is the latest, Repentence update of Apocrypha, almost doubling the number of items in the mod. Apocrypha has items, trinkets, enemies, challenges, transformations, pills and cards, and even a whole new type of consumable: Floppy Disks! All the details for the full mod's con...10.7k downloadsupdated 15 mo ago
- Swaggy Mushroomsby 76561198876704734resprites mushrooms to look uhhhh different also comes free with a flooded caves alt sprite HUGE thanks to Castiel for fixing our issues with the flooded caves alt champion sprites! commissions still open :310.6k downloadsupdated 4 y ago
- Envy but betterby 76561199075010917Envy trollface Yuh10.6k downloadsupdated 3 y ago
- TETO BEGGARby 76561199172310537This mod replaces the devil beggar and hellgame sprites with kasase teto!1!10.5k downloadsupdated 12 mo ago
- Dark Matter Bossby GuilhermeA new boss appears, now from Kirby universe, you can find it as the boss in the Gehenna floor or a little rarely in common rooms in the Dark Room and Chest floor UPDATE: there's a modpack containing all of my bosses now, check it here: It has it's own music from the original game (you can disable...10.5k downloadsupdated 3 y ago
- (Rep+)Hard mode major bosses patternsby DotThis is Repentance+ version of the mod, AB+ version is here : This mod adds new patterns and phases of major bosses in hard mode. Also involves some pattern enhancements and resprites. In addition, new patterns, phases and shields can be enabled or disabled in Dead Sea Scrolls menu. This mod is s...10.4k downloadsupdated 5 mo ago
- Nya Esauby GoganidzeNow the dark Esau has cat ears ... and a badly drawn dash.10.4k downloadsupdated 5 y ago
- Abortionbirth+by NarilliaEverybody knows and loves Abortionbirth, but we know it doesn't quite "fit in". To appease those who need their game to mesh together in a fun and coherent way, we hereby present... ABORTIONBIRTH+! The total conversion overhaul mod for Afterbirth+ that brings the DLC up to the quality we expect f...10.4k downloadsupdated 9 y ago
- Carrionsby Ant Chan# Rotten Gaper Variants Expansion — 19 New Types! **The Corpse floor just got a whole lot nastier.** This mod adds 19 brand new Rotten Gaper variants, each with unique appearances and behaviors. Say goodbye to predictable fights—and maybe your appetite. --- ## Overview This mod expands the Rotten...10.4k downloadsupdated 16 mo ago
- Spamton Sfx For Satanby HululuChanges Satan and Mega Satan's sound effects (that aren't already in the spamton instead of satan mod) to sounds from Deltarune (also affects things that use the same sounds) (the spamton satan reskin is made by Ridler)10.3k downloadsupdated 5 y ago
- Mulligrimsby ScayzeMulligrims! More Grimaces. This mod adds some simple new monster variants to the game: Mulligrims and Nest Grimaces! These Grimaces cough up flies and spiders respectively until the room is cleared! There is a limit on how many flies and spiders they can spawn, so you won't get too overwhelmed! T...10.3k downloadsupdated 10 y ago
- Everyone is Isaacby RidlerISAAC AND HIS ISAAC... Everyone Is Isaac! A resprite mod that changes nearly every enemy and boss into Isaac! Creating the Best Isaac and his Isaac experience you can get! This is a long awaited update to the worst attempt at The Binding of Isaac ReIsaac mod ever. This mod changes: - a lot of ene...10.2k downloadsupdated 19 mo ago
- Gutso the Greatby blorAfter being finished nearly 2 years ago, Gutso the Great has finally appeared in the Depths! (and also Necropolis and Dank Depths but not as commonly) Requires Custom Stage API I remain, BlorengeRhymes P.S. Thank you fiendfolio people for testing and balancing :)10.1k downloadsupdated 5 y ago
- Double Trouble+by Пардон{-------------------------------------} X2-Money X2-Hearts X2-Bomb X2-Boss and monsters 2x Mom's Heart 2x items Black market 2x Isaac 2x Hush 2x Mini Boss 2x Delirium⊙﹏⊙ Good luck!10.0k downloadsupdated 9 y ago
- (AB+ Only) Customizable Game Over Screenby TaigaTreantNOTE: As of Repentance v1.7.7, game over support has become official. This mod is no longer necessary, as a result, and will create issues if enabled. Thank you for your support. Customizable Game Over Screen is a mod intended to expand the capabilities of modders in editing the game over screen....9.9k downloadsupdated 6 y ago
- mulligan respritesby 76561198876704734does what it says on the tin commissions still open9.9k downloadsupdated 3 y ago
- better pootersby 76561198443814292pooters now move quickly over rocks!9.9k downloadsupdated 4 y ago
- cool ANGEL STATUE modelby 76561199192206099This mod changes the angel's model :39.9k downloadsupdated 4 mo ago
- Green Mall Wizard Gnome - Maggot Replacementby 76561198877204046Changes maggots into small mall wizards! Thank you for including me in the Most Popular Items in the past week <39.8k downloadsupdated 2 y ago
- Rooms Galore! Fiendish Editionby 76561198325454024Rooms Galore! Fiendish Edition is an expansion to the Fiend Folio Reheated mod that adds up to 2500+ new rooms! And much like Rooms Galore, Fiendish Edition also comes equipped with a more interesting void floor!9.8k downloadsupdated 4 y ago
- DOOM in Isaac!by PoondaedalinWarning: This mod may not be suitable for people who are sensitive to flashing lights or effects! If you want to play the first level with mouse look/firing, click here! (note: just the first level) "Can it run DOOM?" "Yes, yes it can." "...sort of." This mod contains a few levels of a DOOM/Wolfe...9.8k downloadsupdated 14 mo ago
- Extra Goreby ZERBI-XCVIIDescription Extra Gore: more blood, more gibs and bigger enemy explosion for a better slaughter experience! How it works When enemies are killed, they explode into gibs/blood thanks to a combination between the effects of the special seed "BLOO OODY" and the effect "EXTRA_GORE". In addition: - wh...9.7k downloadsupdated 22 mo ago
- Peter Griffinby fasolpleyer12peter funny mod most fatties are now peter griffin, i wont spoil them all for you but there are a few some still need some work but ill get to it eventually any feedback is appreciated Planned changes: Mega fatty will become MEGA PETER!!! More Peter griffin More animations Inspired by:9.6k downloadsupdated 5 y ago
- Femboy Pootersby lesserStarFemboy hooters pooter9.6k downloadsupdated 5 y ago
- Battle Fantasyby 76561198881880834If you are on Repentance+, a more updated version of the mod can be downloaded HERE!! Battle Fantasy MOD is a medium sized content mod made with appreciation for Isaac and its Flash roots. Over 2 years in the making, the mod has grown to add the following features: Several items based on classic...9.5k downloadsupdated 7 mo ago
- Pickups Aliveby 76561199011865031Now compatible with Mod Config Menu! Set up the spawn rate for Pickups Alive and the added chance given by Tiny Sack. ---- ¡Ahora compatible con Mod Config Menu! Configura la tasa de aparición de los recursos vivientes (Pickups Alive) y la probabilidad añadida por Tiny Sack. ---- Adds an "alive"...9.5k downloadsupdated 5 y ago
- Genesis+ Septic Shock!by budjmtSomething smells funny beneath the Caves... After over 2 years, let's go to the Septic! - Septic is back and in the best shape of its life! It's been ported to the newer StageAPI for greatly enhanced stability and performance. - To access the floor, go to Ch 2 and look for a greenish rock. - The...9.4k downloadsupdated 7 y ago
- Better Challenge Roomsby NiroHarder challenge rooms + much better rewards! This mod makes challenge rooms harder by spawning a harder set of enemies. After you clear the challenge room you get a random item! If you clear the challenge room without taking damage, you also get 2 rare pickups! You can decide how many items and...9.3k downloadsupdated 4 y ago
- Gaper Costumes!by Poondaedalin"Gapers are cool and all, but what if they had funny costumes?" Adds 60 75 120 155 new random head sprites for Gapers! Also has compatibility with Reworked and Revamped Foes! Additionally, you can press "L" with or without Mod Config Menu enabled to access a menu of all the costumes. From there,...9.3k downloadsupdated 3 y ago
- [Rep/Rep+] All hanging replaced by Sayoriby 76561198922002973This mod replaces all hanging guys keepers (special too), for Sayori from Doki Doki Literature Club. It also changes the hanger enemies.9.3k downloadsupdated 2 y ago
- [AB+/Rep] FUCK THIS ROOM IN PARTICULAR+by LeftieTested on Repentance only, but should be fully compatible with Afterbirth+ as well. Originally meant to remove one specific blue spike trap room from the Depths/Necropolis/Dank Depths, this mod removes all rooms with blue spike blocks that I consider unfair. Which is, like, 90% of all rooms with...9.2k downloadsupdated 5 y ago
- Imposter Mushroom [CHAMPION SPRITES BROKEN]by yungtibetsouljaReplaces the mushroom with a venting Among Us imposter9.2k downloadsupdated 5 y ago
359 enemies mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

