The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Lost Plushie (item)by SinstharBored to have 10 familiars behind you and having trouble to dodge the enemies projectiles with all this on your screen ? This mod is made for you ! Find the Plushie in the shop, buy it and all these familiars will disappear. The Lost Plushie give you all the benefits of the old items, so don't wo...9.5k downloadsupdated 10 y ago
- Cornucopiaby Custom PhasePassive item. Spawns a set of 8 consumables at the start of each floor. Consumables list: - Full OR half red heart - Full OR half soul heart - Penny OR nickel or dime - Single OR double key - Single OR double bomb - Battery charge - Random card OR random pill - Random trinket Item pools: - Treasu...9.5k downloadsupdated 10 y ago
- Jacob and Esau Share Itemsby DevNo Twin Left Behind Jacob and Esau now share every item (active and quest items excluded). If one twin picks up an item, the other gets it too. No more deciding who gets every pedestal! Balanced To compensate for the doubled items, both twins have their stats reduced by 35% (each stat is configur...9.5k downloadsupdated 2 mo ago
- Shygal Mask of Infamyby scroontHair not included.9.5k downloadsupdated 5 y ago
- Battle Fantasyby 76561198881880834If you are on Repentance+, a more updated version of the mod can be downloaded HERE!! Battle Fantasy MOD is a medium sized content mod made with appreciation for Isaac and its Flash roots. Over 2 years in the making, the mod has grown to add the following features: Several items based on classic...9.5k downloadsupdated 7 mo ago
- Another Planetarium Resprite Modby 76561198345870300Yep. Another one of these again. Gives the Planetarium items a bit more flair by editing their sprites to resemble their abilities in some way, shape, or form. Might do this with the rest of the "symbol" items, like the Zodiac items, Brimstone, etc.9.4k downloadsupdated 3 y ago
- Cutest Blood Puppo!by An Emo CowBlood puppy is cute, yes. But what if blood puppy was even cuter? And actually looked like a puppy? This visual mod makes blood puppy the pinnacle of cuteness! What a good puppo!9.4k downloadsupdated 5 y ago
- Mini-Minby bethanw10Repentance Compatible Adds a new familiar item based on Min-Min. Circles enemies and fires tears like a Willo. If she has been shooting at the same enemy for a while she will summon (3 - 6) Willos to shoot at the enemy. Vanilla Synergies Counts towards Conjoined transformation Compatible with Bab...9.4k downloadsupdated 5 y ago
- Genesis+ Septic Shock!by budjmtSomething smells funny beneath the Caves... After over 2 years, let's go to the Septic! - Septic is back and in the best shape of its life! It's been ported to the newer StageAPI for greatly enhanced stability and performance. - To access the floor, go to Ch 2 and look for a greenish rock. - The...9.4k downloadsupdated 7 y ago
- Only Good Itemsby 76561199064076978A mod that causes item pools to only spawn 3 or 4 quality items An exception is the boss item pool has 1 and 2 quality items as well since otherwise health ups would be very hard to come by.9.4k downloadsupdated 3 mo ago
- Uranus Fix [Mostly obsolete for Rep+]by RoaryHave I became "that planetarium items guy" by now, huh?.. Anyways this fixes that Uranus messes up ~60% of on-kill effects. For Repentance+, fixes: Goldened enemies not dropping coins upon being ice-freezed. (Midas' Touch, Eye of Greed) For Repentance, fixes: Goldened enemies not dropping coins u...9.4k downloadsupdated 18 mo ago
- CheatModeby DogeekCheat Mod - A mod that makes the game extremely easy! TL;DR : Huge stats, no curses, carry double trinkets, active items, pills/runes/cards, infinite bombs, keys, item charges, guaranteed devil deal and god room, free shops, hive mind, the soul & BFFs, full mapping on startup. With any character,...9.4k downloadsupdated 6 y ago
- Broken Modemby freezeI think this fits under "80s nerd bullshit", right? Maybe slightly more "90s nerd bullshit" but close enough. --NOW APPEARS IN ITEM POOLS SUCH AS TREASURE ROOM-- The Broken Modem is a passive item that makes random enemies at random intervals "lag" for random amounts of time (within certain bound...9.4k downloadsupdated 10 y ago
- Lost Items Pack Expansionby ENFORLost Items Pack Expansion Mod Made by Enfor *** This Mod Requires Lost Items Pack Mod to work *** compatible with EID 16+ new items 5 active items 11 passive items 1 trinket ----------(o)---------- ---- MUNITUS health 2 hearts 1 black heart damage 4.2 firerate 35 speed 1 Each room every 6 second...9.4k downloadsupdated 7 y ago
- Isaac On Twitch Reloadedby VirtualZer0Allow your audience to participate in the game! This mod gives you the possibility to connect your Youtube and Twitch chats, giving your viewers the ability to vote for what's happening on the screen. Features - Events Viewers can choose special events that have different effects on your run - Su...9.3k downloadsupdated 5 y ago
- Hey That's Pretty Goodby GentimalReplaces coin pickups with "Hey that's pretty good", key pickups with "That's midly adequate", and good effects with "Salamander NYEEEES" taking damage with "Hmm watcha say" death screen with "Sad Violin" I'll improving this mod more and more guys, keep it up, proud of you!9.3k downloadsupdated 10 y ago
- Fair Co-op Items (Online)by ArtuurIMPORTANT REQUIREMENT To use this mod in online multiplayer, it is strictly required to have Isaac Online Modded installed. MOD CONFIGURATION & DESYNC WARNING To customize this mod's settings, you need to install Mod Config Menu - Impure. CRITICAL ONLINE INSTRUCTIONS: ALL players in the lobby MUS...9.3k downloadsupdated 28 d ago
- Aintramural (REP | AB+)by [ZG] Zandorum"Where am I?" ► Features - When entering a new room, there's a 1/6 chance to create a new room of the same type. Though be careful, as these rooms cannot be accessed again once you leave. - Available in the Devil Item Pool for 2 Hearts. - Duplicated boss rooms can have any boss in the game, with...9.3k downloadsupdated 5 y ago
- Malware & Spam - The forgotten Modern Horseman of the Apocalypse [RGON]by DüpsyThe forgotten Modern Horseman has appeared in the Basement! The forgotten Modern Horseman of the Apocalypse Malware and his trusty steed Spam have appeared in the Basement, flooding your screen with malicious software, intrusive ads, and endless spam. Like a virus burrowing into the heart of our...9.3k downloadsupdated 20 mo ago
- [AB+ Only] cHUD2.3 Liteby ConnorsseurHave you ever found yourself unsure of what items you picked up earlier in your run, or unsure of what it was that killed you? Well then cHUD Lite is perfect for you! It colors each and every item, enemy, and boss portrait in the game! Yay, colors!!! This mod is only compatible with Afterbirth+....9.3k downloadsupdated 6 y ago
- [REP] Your Favorite Familiar Mod - Baby Reskin modby peasThis mod reskins most familiars in the game to be consistent with one another, and a lot more adorable! There are still some missing familiars that need reskinned, so this mod will probably get updates in the future. Enjoy! Also, check out Lifebar if you're looking for another reskin mod to go al...9.3k downloadsupdated 5 y ago
- Intrinsic Babylonby 76561198412573006What it do? This mod replaces Eve's Babylon starting item with an intrinsic version, similar to how The Lost's Holy Mantle works. But why? This prevents Eve's main gimmick from being removed or rerolled, making the character exactly 3% more unique. Credits ratratrat: Mod Conceptor/Programmer Ferp...9.2k downloadsupdated 3 y ago
- RAF Floppa over Dead Catby Steven Mcribble: Trackpad Techlowest effort mod on this workshop replaces the dead cat familiar with cube floppa from raf9.2k downloadsupdated 4 y ago
- Better first floorby PetergenicsI got really tired of pressing r and not checking the first item room of every seed, and the other better start mods that i found in the workshop are op as fuck so i made this mod. ADDED MOD CONFIG SUPPORT What this mod does: 1- remove curses on the first floor (does not remove curse of labyrinth...9.2k downloadsupdated 5 y ago
- Troll Bombsby ElRichMCChanges player's bomb to troll bombs, gives 10 bombs.9.2k downloadsupdated 10 y ago
- Hyperhydrationby NiroFill your enemies with water until they blow up! This item makes you shoot water out of your eyeballs. If an enemy got hit by your shots, when he dies he blows up into water! The more shots you hit the enemy, more water the enemy blows up to! The enemy can explodes into a max of 10 tears. The tea...9.2k downloadsupdated 5 y ago
- Broken 20/20 (Afterbirth+ and Repentance)by NestorBech-Fixed item pool and costumes animations!- This mod includes a new passive item: Broken 20/20! This item fire two tears (like 20/20). One of them is like Anti-Gravity but you can't fire it. Also includes costumes animations of 20/20 and Broken 20/20. It appears on Treasure item pool and Greed Tre...9.2k downloadsupdated 10 y ago
- UMA overhaul [DISCONTINUED]by Greenagon! If you want only specific things from this mod please download it and make your own smaller packs so I don't have to flood the workshop with them ! UMA overhaul is a ( work in progress ) graphical mod that changes a few sprites of the game. I personally like these custom textures more but due t...9.2k downloadsupdated 8 y ago
- isaac porroby 765611992006219559.1k downloadsupdated 7 mo ago
- better crowns [outdated]by 76561198876704734THIS MOD IS OUTDATED. GET THE 2.0 VERSION WITH BETTER SPRITES AND DARK PRINCE'S CROWN DIAMOND VISUALS BAKED IN HERE This mod makes crowns look like they're made of some kind of crystal or glass. If you want dark prince's crown to also make your tears into diamonds, you can download this mod: by M...9.1k downloadsupdated 5 y ago
- Some more bumsby ☢ Nato Potato ☢This mod adds 3 more bums to the game: Fire Bum, Rock Bum and Loot Box Bum. Fire Bum: breaks fires, spawns 1 penny per 2-4 fires broken (fires can still drop regular rewards, it can break blue and purple fires) Rock Bum: breaks tinted rocks and super special rocks, after breaking 5-10 rocks takes...9.1k downloadsupdated 5 y ago
- Lower Case Tby DrakonnasThis mod adds a new item that turns your tears into T E A Rs! Instead of firing a normal tear, you can now fire the four letters that individually deal 40% damage, to a total of 160% of your normal damage! Synergizes with basically any other tear modification (even other mods!). You can spawn thi...9.1k downloadsupdated 9 y ago
- Fruity Rooms [REP(+)]by 76561199055131226This mod adds a new special room type "Fruity Room" that has a 5% chance to replace treasure rooms and contains items from my game Fruity Rogue. I hope you all like it. You can play with or without repentogon fine, you just need minimapi for the custom icon to show up on the minimap. Item list ca...9.1k downloadsupdated 13 mo ago
- Half-Life Items [REP | 30 ITEMS, 4 TRINKETS!]by CaMpeRThis mod adds 30 brand new items and 4 new trinkets from the Half-Life universe! This is my first item mod so there might be bugs, please report them if you encounter any, i'll try to fix them as soon as possible. Tested on Repentance, might not work on other versions. Detailed item descriptions...9.1k downloadsupdated 5 y ago
- cracked key at homeby Phno 🐙This mod will spawn a cracked key at the home floor, so you don't have to think about it.9.0k downloadsupdated 5 y ago
- pochita modby MelanChanges the sprites for "Blood Puppy" item into the character Pochita from the manga "Chainsaw Man".9.0k downloadsupdated 22 mo ago
- Ghost Pepper Rework!by Mr. HeadcrabThe beloved Ghost Pepper is looking hotter than ever! This all new Ghost Pepper shoots out the same white flame you can find in Downpour, one that will exorcise any monster in it's way! These disembodied souls are far weaker than the hosts they come from, and will prioritize getting back into the...9.0k downloadsupdated 3 y ago
- Old Skullby ☢ Nato Potato ☢You're not sure who this belonged to but it should come in handy. Gives 2 bone hearts and makes skeletal enemies like bonies and hosts friendly as long as you have at least 1 bone heart, so try to hang on to them. It can be dropped by Death, Carrion Queen, the Frail and the Forsaken. (but not if...9.0k downloadsupdated 2 y ago
- Bottom Lineby QWiiRock Bottom on a budget! Found in the shop or Greed Mode shop for 15 cents, Bottom Line is a new item which adds minimums to your stats. Specifically, you will not be able to go below: 1 speed 1 fire rate (also known as tears) 3.5 damage 6.5 range 1 shot speed 1 luck Any item which tries to reduc...9.0k downloadsupdated 3 y ago
- the binding of maggy's toy box and WOB isaac's secret stashby 76561199032451894BUG FIX: 超级撒旦和鲍勃的烂头动画修复! MegaSatan and Bobsrottenhead Animation fix! 炸弹乞丐被炸不出炸弹修复! Fixed the Bomb Bum not dropping an insta-exploding bomb when blown up! 究极傲慢宝宝瞎几把乱闪修复! Fixed the Ultra Pride Baby incorrect flashing animation! 个人整合包,非原作者,模组来源: maggy's toy box maggy's toy box reborn WOB isaac's sec...8.9k downloadsupdated 12 d ago
- A few more bumsby ☢ Nato Potato ☢This mod adds 3 more bums to the game: Poop Bum, Battery Bum and Spider Bum. Poop Bum: breaks poops and spawns 1 blue fly per poop (poop can still spawn random stuff when broken) Battery Bum: picks up pennies and recharges 1 tick of your active item per penny (doesn't take them unless you have an...8.9k downloadsupdated 5 y ago
- Start with Birthrightby BarjuhStart each run with Birthright Collection with all my Start with mods :8.9k downloadsupdated 3 y ago
- (AB+ VERSION) The Binding of Undertaleby CakeThis mod replaces characters, music, end bosses and floors with Undertale content! Enjoy! THIS IS THE AB+ VERSION OF THIS MOD, AND WILL NOT BE UPDATED. CHECK THIS FOR THE REPENTANCE VERSION Spriting by Cake and Opscat AB+ porting by abcbadboy Expansion Content by Spearkiller and special thanks to...8.9k downloadsupdated 5 y ago
- The Binding of Isaac: Eternal Youthby snooch"The Binding of Isaac : Eternal Youth" Is planned to be a huge content pack for the game! This is a mod made from a small bunch of people who share similar passion for the game. Current Content ============== 10 Items Abomination Baby - A familar that likes to reward you with a troll bomb at the...8.9k downloadsupdated 10 y ago
- EasyModby MrMigglesEasyMod spawns a random item at the start of each run. Items are chosen from a pool of powerful and interesting items, and are sure to give a boost to the start of your run.8.9k downloadsupdated 10 y ago
- Rooms and Roams (700+ rooms)by MarbleTearsHello, welcome to Rooms & Roams!! an expansive mod for more adventures This mod add Adds: 100+ rooms for every chapter (basement, caves and depths) 50 + rooms for every alts (burning basement, cellar, etc) 50 + rooms for every alt2 chapter (downpour, mines, etc) + 200 special rooms (planetariums,...8.9k downloadsupdated 14 mo ago
- Cat-astrophe [Catgirl with gambling addiction - Awesome edition]by 76561199090151127What a catastrophe of a mod - Me ------------------------------------- Content 2 Character 19 Items 12 Trinkets 15 Pickups 3 Challenges and more :) ------------------------------------- Compatible EID (has spanish and ingles) Encyclopedia Fiend Folio Retribution Epiphany Library expanded Repentan...8.9k downloadsupdated 2 mo ago
- Unlocks Reminder [Chinese]by 🇬 🇷 🇦 🇮 🇱 🇸在原版上替换了汉化内容 Unlocks Reminder: 12.30更新内容 -去掉强制中文,根据所选语言显示8.9k downloadsupdated 22 mo ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

