The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- 56 Leaf Cloverby VladirienThe 56 leaf clover from Risk of Rain. Simply gives a small chance (~5%) of spawning collectibles when killing champion enemies. Available at the shop. Original design from Risk of Rain, ported by @vladirien8.2k downloadsupdated 10 y ago
- 警长中文eid图鉴/z_Sheriff_EID_Chineseby YouDuckBoom8.2k downloadsupdated 2 y ago
- Lil Spewer (Now in Booster Pack #5)by MozzieNow officially in the game! (2018/04/30) "Puking buddy!" Adds a brand new chargeable familiar to the Treasure Room pool! When picked up, a random pill is dropped on the floor. Gives Isaac a follower that shoots charged creep shots whose damage and pattern changes depending on Lil Spewer's variant...8.2k downloadsupdated 9 y ago
- [UNTITLED] Token Over Tainted Samsonby 76561199510539468TOKEN OVER TAINTED SAMSON!!!!! RATED T FOR TOKEN :3333333 Includes: -TOKEN. -TOKEN. -7 FEMT THEMED ITEM RESPRITES. -TOKEN. -TOKEN. -TOKEN. -2 COSTUMES. -TOKEN. -AND EVEN MORE TOKEN. TOKEN belongs to FEMTANYL . (updated 5.24.26) Femtanyl tracks over berserk sounds (read the instructions ig) [8.27....8.1k downloadsupdated 7 mo ago
- Charged Bombsby ☢ Nato Potato ☢Charged Bombs zap nearby enemies with electricity until they explode, picking this up also gives you 5 bombs. They can only zap so often, but can zap multiple enemies at a time, so chuck them into groups of enemies for optimal effect. Compatible with Better Bombs mod Combine with Acid Bombs to de...8.1k downloadsupdated 4 y ago
- Murasama (alpha)by 76561198802955004Start blood-ment with new weapon - Murasama Split monsters wide open! Actually a working mod 0_0 Alpha testing: resprite of spirit sword (Isaac's awakening is OP), resprite Tainted Samson to Jetstream Sam (Donkey Jaw resprited to Murasama) To do list: Charged shot New sound effects Murasama as a...8.1k downloadsupdated 4 y ago
- Isaac is sus characters and dripby 76561199080435951OH MY F*CKING GOD, ISAAC IS SUS This mod add two new characters: Amogus and the imposter and replace ventricle razor for vent Coop compatible Among us Drip8.1k downloadsupdated 5 y ago
- Lil' Moleby DrakonnasAdds a little mole familiar that digs up gems while you fight enemies! He will continually collect and drop gems on the floor, and pickup those gems will grant you stat bonuses for the current room, depending on the gem collected. Available gems: - Ruby : Grants damage - Sapphire : Grants tears -...8.1k downloadsupdated 9 y ago
- MattPack Extras: D-Section! [RGON]by Mr. HeadcrabThis mod requires and Dynamic Minisaacs Forever! This mod adds the Quality 5 C-Section upgrade commissioned by Lazy Mattman, D-Section! All of your tears will be replaced by special, temporary Minisaacs that inherit your weapons, stat modifiers, and tear effects! You can obtain it my transforming...8.1k downloadsupdated 9 mo ago
- cat modby 76561198882315368I made a graphic mod to change some sprites like stoney, stone grimace, penny donation machine and turn them into golem cats and cat penny8.1k downloadsupdated 4 y ago
- Mixed Boss Collection Part 1by GuilhermeThis mod is a pack of all my boss mods, does to limitations of how many values a mod can save then It doesn't contain all the bosses, CLICK HERE for the part 2 of the mod and HERE for the part 3 of the mod it also features it's own menu config to change which bosses do you want and which ones wit...8.1k downloadsupdated 3 mo ago
- Repentance Darkened Lootby 76561199698167290**Forgotten Treasures - A Custom Visual Pack** A visual overhaul that replaces various pickups, chests, and doors throughout The Binding of Isaac: Repentance. Explore the game with a completely refreshed look for important objects and rewards. **Features:** • New pickup textures • Redesigned ches...8.1k downloadsupdated 4 mo ago
- Fisherman's Endby RyouThis mod adds the item Fisherman's End, which grants you Range Up and the ability to shoot tears that leave a damaging trail of water. Definitely not a reference. This item is found in treasure rooms and the shop! Thanks to Funnynin with the code, again!8.1k downloadsupdated 6 y ago
- No Useless Heartsby Iris HeartThis mod makes every base game character able to pick up and utilize any base game heart! Details below. This mod is a mainly a compilation mod of my other smaller mods that are aimed at individual characters, except for Blue Baby who doesn't have his own separate mod by me, because such mod exis...8.1k downloadsupdated 4 y ago
- Red Shoesby ☢ Nato Potato ☢These familiar red shoes will significantly increase your move speed and give you an interesting health mechanic which allows you to retain hearts, but also makes things more challenging. If you take damage while having only red hearts, or only soul/black hearts, all but 1 half heart will be drop...8.1k downloadsupdated 2 y ago
- Denis (+11 unlocks) [RGON]by Dracula joeThis mod requires REPENTOGON, it will not function properly without it! Say hello to Denis (and his offspring)! Denis' Mechanics Denis can't fire tears and must instead rely on his horde of Minisaacs to attack for him. - He can charge up to mitose a new Minisaac, and can have more Minisaacs the h...8.0k downloadsupdated 18 mo ago
- Oh, My Spoon (Deluxe)by ochoSeizure warning for the 2nd youtube video attachment, I guess. This mod is a simple reskin + rename of the Wooden Spoon -- it also plays a short sound effect when you pick up the item. Full disclosure: it was made entirely using unoriginal code: I used dedi's ezitems-web tool over on GitHub And s...8.0k downloadsupdated 4 y ago
- Item Beggarby ☢ Nato Potato ☢The Item Beggar asks for items and gives you a different item in exchange, think gun munchèr from Enter the Gungeon. It will give 1 item per 2-3 items given to it and will fly away after giving 3 items, it can spawn items from a variety of different item pools, like devil deal, secret room and bo...8.0k downloadsupdated 3 mo ago
- Serafemby rotexorOriginal art from the Maggy's Toy Box mod by Minygold Original code from the SucQTbus mod by Ivy Art edited to add clothes by rotexor. Code edited to add BFF support to turn from blue (Uriel) clothing to red (Gabriel) clothing by rotexor. Mod idea by BamB.8.0k downloadsupdated 3 y ago
- USoEI (Unique sounds of each item) 1.54vby 76561199061435092! ATTENTION, THERE ARE LOUD SOUNDS AND SWEAR WORDS IN THIS FASHION! 730 unique sounds for each item, a bunch of Easter eggs and references!!!!! Description I was able to collect 730 sounds for each type of item, each item has its own unique sound. There are a bunch of Easter eggs and memes here,...8.0k downloadsupdated 2 mo ago
- MegaBrimby KyoZMSUPER OP JUST FOR FUN! Youtube video by ZOAG8.0k downloadsupdated 10 y ago
- The Binding of Brazil (AB+)by TCDubs✎ 𝗥𝗲𝗽𝗲𝗻𝘁𝗮𝗻𝗰𝗲: --------------- A Tradução Brasileira de "The Binding of Isaac: Afterbirth +" ~Todos os Itens e Suas Próprias Descrições ~Pílulas, Cartas, Runas e Suas Descrições ~Alguns Nomes de Bosses ~Os Desafios ~O Bestiário ~Interface ~Todas as Conquistas ~Booster Pack 1,2,3,4 e 5 ~Andares ~ S...8.0k downloadsupdated 8 y ago
- Visible Alt Path Treasureby cybershadow95Tired of choosing the worse item in the Alternate Path Treasure Rooms? This mod will make both items visible, just like they were in Antibirth. Compatible with Fall From Grace and Last Judgement!7.9k downloadsupdated 21 mo ago
- Brainrot Edition!by 76561199844292366Those who know..💀7.9k downloadsupdated 18 mo ago
- Cricket's Tailby SalvageReusable Chest Generator Active Item - 3 Room Charge Generates a chest with a higher chance of a special chest than usual! Chest Probabilities Normal Chest: 40% Spike Chest: 20% Red Chest: 20% Golden Chest: 10% Stone Chests: 9% Angel Chests: 1% Itempools: Treasure Room Pool Shop Pool Golden Chest...7.9k downloadsupdated 10 y ago
- Golden death certificateby 76561198819178327Golden death certificate. This certificate is like normal, but he's not disappear. Made for fun "Are you dead again?" Quality: 4 Charges: 32 Pools: Treasure, Secret, Greed Treasure Game does not show more than 12 charge bars, so the charge is displayed incorrectly.7.9k downloadsupdated 5 y ago
- Brimstone Bombsby KubeRootAdds an item that makes bombs fire short spinning brimstone beams before explosion Now added to the pools! Huge thanks to Xiapher for making the item sprite7.9k downloadsupdated 10 y ago
- Start with Mutant spiderby BarjuhStart each run with Mutant spider Collection with all my Start with mods :7.9k downloadsupdated 4 y ago
- Health Insuranceby ☢ Nato Potato ☢Health Insurance is a custom active item which allows you to buy heals before you need them. Using Health Insurance takes 3 coins from you (not working if you have less) and turns heart pickups in the room into coins, when you have empty heart containers it will heal you half a red heart for each...7.9k downloadsupdated 5 y ago
- Cactusby ☢ Nato Potato ☢The Cactus makes you so prickly that any enemies that try to deal collision damage to you take damage and run away instead! You can take out enemies by running into them, just try not to get hit by projectiles/fires/explosions/etc, as those will still hurt. Keep in mind it will slow you down, a l...7.9k downloadsupdated 9 y ago
- buwenby 76561198347365682=BuWen Mod= 【Mod内容】 ①共计580 左右新的道具。 ②30位新角色(15表角色+15里角色) ③7种mod特有角色属性(基础攻击力、暴击率、暴击伤害、攻击力加成、最终伤害、技能加成、冷却缩减) ④34种“精英技能”;全新机制,怪物生成时有概率被赋予随机技能效果,每个“精英技能”有着各自各样的效果 ⑤12种“精英怪物”;全新怪物,不同怪物有着自己的攻击方式以及特殊机制。 ⑥添加伤害飘字显示,反馈拉满。 ⑦35 种以上新的卡牌、32 种以上新的药水效果、新的8种套装效果。 ⑧空想神话装备体系(完美还原崩崩,膨胀的开始) ⑨难度选择机制,可更具游戏进程和发育情况修改难度。以及...7.9k downloadsupdated 8 d ago
- PLUSH REI COINby 76561199025488140This is my first work with animation, if you find a bug or something else, then write in the comments7.9k downloadsupdated 4 y ago
- Lil Delirium respriteby O_oI can never tell Delirious and Lil Delirium apart just by looking at their item sprites. So, I decided to make things less confusing by making the sprite of Lil Delirium look like a familiar.7.8k downloadsupdated 9 y ago
- pudzian bumbinoby 76561198334935970POLSKA GUROM7.8k downloadsupdated 4 y ago
- Good Deals [FIX]by 76561198865227624Increases the chances of good items in deals and adds new predictions to the fortune teller machines The mod no longer conflicts with other mods that add new items7.8k downloadsupdated 4 y ago
- New Character: Ennui!by PoondaedalinIntroducing Ennui: the root of all worldly sins! (or at least some of them) - Can swap between one of eight aspects with unique upsides and downsides! - Risk-reward system stemming from overusing one specific sin over others -- A full set of 15 unlocks items related to the character! - Hopefully...7.8k downloadsupdated 3 y ago
- MORE no more symbolsby 76561199175201857No More Symbols by hemomaddie is a great mod that replaces the textures of the "symbols" items in the game. This mod tries to expand that amount, by imitating the style of hemomaddie's items for other mods with their respective symbols. This mod is compatible with: - Repentance Plus! - Andromeda...7.8k downloadsupdated 4 y ago
- The Librarian [Ab+/REP]by AgentCuccoThis mod has been tested on rep to work fine, but it might be a bit unstable. Additions This mod adds a new boss to the game: The Librarian. This boss has a 25% chance of appearing in libraries (similar to Greed). The boss possesses two different phases, however the second phase is exclusive to H...7.8k downloadsupdated 6 y ago
- Oh No, our Mantle!by 76561198335335852A simple little mod that replaces the sound of the holy mantle breaking, to that of the iconic glass shattering sound of the funny table.7.8k downloadsupdated 2 y ago
- Infinite coins [REP(+) AND AB(+)]by 76561199124047182Infinite Coins! 💰 Never run out of coins! Auto-refills to 99 everytime. Works on AB+, Repentance & Repentance+! Shops, machines, donations: Spend freely. No achievements broken. More from me: 🔑 Infinite Keys 💣 Infinite Bombs7.8k downloadsupdated 10 mo ago
- Upgraded Tech! - Tech Respritesby GonkEver looked at the Tech set of items and thought: "Hey, these are good sprites, but I'd like a little extra flair in them." No? Well have I got the mod for you! This is mainly just a test with Isaac modding, but I felt like doing some resprites of the Tech set just for fun. The changes for these...7.8k downloadsupdated 4 y ago
- Dark Bum holds... a bowtie!by 76561198391458240He looks very dapper Also I know that an extra Dark Bum shows up in the debug menu when this mod is installed I don't know what causes that or how to fix it sorry7.8k downloadsupdated 5 y ago
- Berserk! The Crucible Blade (Doom Slayer Swort) [Rep]by 76561198828705706RIP AND TEAR... I recomend complement whit this mods: Enjoy :) Esp: Recomiendo tener instalado con estos mod: Disfruta :)7.7k downloadsupdated 5 y ago
- Consistencyby ☢ Nato Potato ☢This mod adds 2 passive items to the game. 1 item causes all of Isaac's tears to change direction whenever you fire a new tear so they all travel in the same direction, similar to tractor beam, but without teleporting the tears across the room. The other item gradually boosts Isaac's damage and t...7.7k downloadsupdated 9 y ago
- [REUPLOAD] Aladar's Worm Item Respritesby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...7.7k downloadsupdated 17 mo ago
- Homestuck Star Signsby vulpvulpesChanges all the star sign items to have the colour of their respective Homestuck trolls. Probably done before, but whatever7.7k downloadsupdated 7 y ago
- alt. Book of Secrets sprite!by ViscerANow the book's sprite is more reminiscent of its effects. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading every sprite tweak separately, so that if you don't...7.7k downloadsupdated 5 y ago
- Lizby OriginemIt is a mod that contains a gym girl and some items... Gymnastic Girl:Liz Only Single Player Play as liz, A mesmerizing gymnastic girl. Her every move carries an amazing charm that can put even monsters into intoxication. After the death of the monsters she charmed, there is a high possibility th...7.7k downloadsupdated 6 y ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

