The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Spirit Sword - Lobotomy Corporation Reskinby 丧病Replaces Spirit Sword with Mimicry, the E.G.O. weapon of Abnormality O-06-20 "Nothing There" from Lobotomy Corporation, including its custom sprite and visual effects.7.1k downloadsupdated 4 mo ago
- Isaac's Limbusby 76561199214294443A full Limbus Company character expansion for The Binding of Isaac: Repentance Currently, it adds the first five Sinners in Canto order: Gregor Rodion Sinclair Yi Sang Ishmael It also includes Tainted Gregor and Tainted Rodion, along with unlocks for every character. Features: 180+ custom items a...7.1k downloadsupdated 2 mo ago
- Greed's Blessingby KerkelGREED IS GOOD!!! The Greed Donation Machine has no use after unlocking the Keeper, but keeps stubbornly showing up anyway. Time to give it the spotlight again! Donating 33 coins to the Greed Machine after the Keeper is unlocked will now make your next normal run start with an additional random it...7.0k downloadsupdated 17 mo ago
- Cursed Heartby nickCURSED HEART Speed + DMG up, no more hearts! Type: Passive Effect: Increases speed and damage, but prevents red hearts from spawning. However, you fully heal at the start of every floor. Pools: Treasure, Curse, Secret, Devil Cursed Heart is a passive item that fits into a high risk, high reward p...7.0k downloadsupdated 10 y ago
- FIRE IN THE HOLE!!!by 765611988029550047.0k downloadsupdated 26 d ago
- Spawn Room OP - Repentanceby ThirstyPengnHere is the updated mod which includes bonus rooms rather than changing the start room and the greed mode items will no longer crash the game: I threw together some of the strongest items I could think of for running through a game. These are not randomized, so the same items will be there at the...7.0k downloadsupdated 4 y ago
- Wario's Cap | Every Copy is Personalizedby AgentCuccoThis item can give Speed, Tears, Damage, Shotspeed or Luck, or even all of them at once! Every player gets a personalized modifier! The stats the item gives are determined on the user, not the run, meaning that every person who installs the mod will get a completely different item from the rest....7.0k downloadsupdated 5 y ago
- Psy Fly Unnerfby NullPsy Fly shoots homing tears again and no longer goes into a 1 second cooldown. Works with BFFS and Hive Mind.7.0k downloadsupdated 2 y ago
- Isaac Reforged [Afterbirth+]by KaliThis mod aims to add and rebalance characters, synergies, and transformations, while remaining faithful to the vanilla experience. Supports External Item Descriptions! Supports Mod Config Menu! Supports Revelations! Supports Fiend Folio! & More! All changes are configurable with the Mod Config Me...7.0k downloadsupdated 6 y ago
- Miku Miku Blastby Apollo JusticeChanges the sound effect for Mega Blast to Miku Miku Beam Made entirely by psyleft7.0k downloadsupdated 20 mo ago
- Kasane Teto as Cube Baby (UTAU)by 76561198350259731Small mod replacing Cube Baby with Kasane Teto (UTAU). I'd change the name and description of the in-game item but I have no idea how to do that. Mod used in showcase:6.9k downloadsupdated 6 mo ago
- Road Roller!by lesserStar-Changes Monstro into a road roller from jojo -So monstro's tooth becomes a Road roller item -the name of the item is not chenged (idk how to do that) Sprite is from Jump Ultimate Stars6.9k downloadsupdated 8 y ago
- [REP|AB+] Zodiac Indicatorby 76561198367241059With Zodiac Indicator you can know what zodiac effect you are getting from the Zodiac item! It will display the zodiac item as a little map indicator (like restock and the compass). It will also (optionally) show you the name and description of the zodiac item. You can customize the mod using Mod...6.9k downloadsupdated 5 y ago
- Noelle Baby and Berdly Cubeby devThis mod replaces the Freezer Baby with Noelle and the Cube Baby with frozen Berdly. Now you can experience what it's like to play with a spell you don't know! (Deltarune spoilers for Snowgrave Route) Mod used for thumbnail(s): The Binding of Undertale & Deltarune6.9k downloadsupdated 5 y ago
- Late Bloomerby SalvageYou'll get there! Passive Item Effect: All stats down, but every new floor you reach gives you an increasing stats up Itempools: Treasure Room Pool Secret Room Pool Credits to /u/KnightNight- for the amazing idea!6.9k downloadsupdated 10 y ago
- Niro's Collectionby NiroA collection of items and trinkets I made! All of them are updated for Repentance and support External Item Descriptions and Encyclopedia ! This mod adds: 14 new passive items 2 new active items 6 new trinkets Passive Collectibles Addiction - I need more pills! Black Swarm - Dark friends Daemon's...6.9k downloadsupdated 2 y ago
- Little Beastby ryon"And the beast which I saw was like unto a leopard, and his feet were as the feet of a bear, and his mouth as the mouth of a lion: and the dragon gave him his power, and his seat, and great authority." - Revelations 13:2 (KJV) "Also, he had a daughter." - Revelations 13:3 (KJV) Introducing, Littl...6.9k downloadsupdated 5 y ago
- Dirtier Mind - The Somewhat Unnecessary Dirty Mind Upgrade!by Mr. HeadcrabSomeone's(?) favorite item has gotten an upgrade! Dirty Mind will now shoot friendly dips out of poop-type and poop-adjacent enemies! All enemies will shoot out their corresponding dip variants, including even some custom skins and behaviors. This mod has full Fiend Folio compatibility, including...6.9k downloadsupdated 3 y ago
- Obama prismby 76561199025488140Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama Obama6.9k downloadsupdated 4 y ago
- Reverb Vine Boom sfx for Holy Mantleby 76561198986475370Replaces holy mantle sound to include vine boom with reverb. Thats it6.9k downloadsupdated 5 y ago
- Mortar Tubeby VladirienThe Mortar Tube from Risk of Rain. Chance to fire an long range mortar when hitting an enemy. Original design from Risk of Rain, ported by @vladirien6.9k downloadsupdated 10 y ago
- Health and pickups packby ☢ Nato Potato ☢This pack has several items that utilize the NoHealthCap and NoPickupCap mods, it also serves as an example for other modders. Dad's Wallet: Boosts coin cap to 250, +25 coins. Bomb Sack: Boosts bomb cap to 250, +25 bombs. Key Chain: Boosts key cap to 250, +25 keys. Cardiomegaly: Boosts heart cap...6.8k downloadsupdated 7 y ago
- Redemption Community Pack [ON HIATUS]by Magpie Smoking a CigNote: This mod is on Hiatus. For more information read it on the discussions page. THE TIME TO REDEEM YOURSELF IS NOW! Redemption adds numerous items, trinkets, monsters, and much more to spicen your runs. We strive to incorporate new and exciting features to the game with a particular focus on c...6.8k downloadsupdated 4 y ago
- UmaModby 76561199084903055暂时只有表角色版的米浴、贵妇人和里见光钻 currently there are only noraml version of riceShower,gentildonna and satonoDiamond 角色机制有点长,所以我放在下载mod文件中 character ability intruduction is too long to put here so i put it in mod downloaded file 以后会有里角色版的三人,以及更多其他小马的加入,如果没有意外的话 the tainted version of them and more umamusumes...6.8k downloadsupdated 9 d ago
- Brimstone on startby v1rBrimstone on start.6.8k downloadsupdated 4 y ago
- Purple Guy and Springtrap!by 76561198843280029-- Purple Guy Enters the Basement ! -- Adds the Purple Guy, William Afton, as a playable character in a unique slot! High damage, low shot speed. Purple tears! Unique item costumes. -- Springtrap Enters the Basement... -- The tainted variant of Purple Guy Fake Hearts Free Devil Deals Special Knif...6.8k downloadsupdated 10 mo ago
- More Pickup Varietyby WofsaugeThis mod adds over 100+ new and unique skins for every pickup in the game. The mod provides an easily expandable spritepool, from which the visuals of any pickup can be choosen. This includes up to 6 new vsuals and the original one, in order to make the gaming expirience less repetitive and more...6.8k downloadsupdated 9 y ago
- TBOI Othersideby 76561199822386179Ever wondered what if there was a mod that adds alternative version to already existing items? Well then i have just the right thing for you! This mod adds 46 new items all obtained with an all new Weird Mirror found inside of the mirror dimension in the secret room Is this quality slop? - No. is...6.8k downloadsupdated 5 mo ago
- Void Unnerfby Elven PrincessBecause infinite Diplopia is fun! This mod gives Void the ability to use one-use items, such as Diplopia or Pandora's Box, multiple times.6.8k downloadsupdated 10 y ago
- Start with Sacred orbby BarjuhStart each run with Sacred orb Collection with all my Start with mods :6.8k downloadsupdated 4 y ago
- Bocchi the rock bottomby Elmenda99Replacing Rock Bottom for Bocchi from the anime Bocchi the Rock6.8k downloadsupdated 4 y ago
- Plump Cutie Succubus!by VixieYoteMakes your damage stat THICC! I return once more with another addition to my Plump Cuties Collection! Up next before I go back to trying more boss replacers, we have a simple resprite of the Succubus! Succubus is a god-tier familiar I always look forward to getting, so I figured I'd offset the us...6.7k downloadsupdated 21 mo ago
- Birdification!!!!by CaMpeRDESCRIPTION!!!! This mods brings the glory of pukeko into isaac by birdifying all possible items. Be aware that this is only a VISUAL MODIFICATION!!!! (and doesn't change any gameplay elements)6.7k downloadsupdated 9 mo ago
- MVmodby Full retardmv's comments when you play Todo: - add "ptit criket's head ?" when opening a chest - add "PAAAFF" when booss die - add "Oh le dime" when get a dime ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Missing sound : If you have any of theses, please send it to me at mvmodsound@gmail.com. - "brillant comme...6.7k downloadsupdated 10 y ago
- Headcrab's Grab Bagby Mr. HeadcrabIt's got all you need for a long journey downwards! This mod adds 5 unique items, 2 trinkets, and 1 consumable: Items: Vienna Sausages "Eat your botulism" Build up pressure as you take damage until you blow your top off, knocking back enemies and shooting out a heavy stream of blood tears for the...6.7k downloadsupdated 14 mo ago
- Yeah I Read Booksby Loud & NoisyThis simple mod replaces all book textures, with new ones that are inspired by the ones from flash. All books have new textures, Including; - Book of Belial - Book of Virtues - Lemegaton - The Bible - The Necronomicon - Book of Shadows - Anarchist Cookbook - Book of Revelations - Book of Sin - Mo...6.7k downloadsupdated 5 y ago
- Dice Shotby RensBThis mod adds a new item called the swallowed dice. The item randomly fires a dice that rerolls enemy it hits into an item or another enemy The item has now been added to item pools.6.7k downloadsupdated 10 y ago
- Medkitby VladirienThe medkit from Risk of Rain. Fully heals Isaac on pickup. Heals for half an heart a few seconds after getting hit for a full heart of damage. Available at the shop. Original design from Risk of Rain, ported by @vladirien6.7k downloadsupdated 10 y ago
- !Recharged!by 76561198448686767!Recharged! - is a mod that changes charged baby's sprites and animations!6.6k downloadsupdated 2 y ago
- Jevil over Chaosby 76561198329067281A mod that change the sprite of our favorite Item "Chaos" into an animated sprite of Jevil from Deltarune. It also change te item description and plays some of the character voicelines when picked up. This was my first mod so it may looks a little spaghetti coded inside hehe6.6k downloadsupdated 4 mo ago
- Sprite Enhancements!by 76561198920139818Modifies item and trinket sprites to make them look cooler. Also Tainted Lost is just more sad.6.6k downloadsupdated 3 y ago
- [UPDATE] Terraria Death Sickle (& Obsidian Skull)by 76561198847459675It's been a while, thanks for all the views and subscription, took me a while to realize how many of you downloaded this terrible resprite, that's why I've remade it -------------------| I've changed Death Touch into Death Sickle from Terraria And instead of changing Isaac into Reaper , I just ga...6.6k downloadsupdated 18 mo ago
- Start with Blue Mapby 76561199626669882Every run starts with the Blue Map (ID: 246), which reveals the locations of Secret Rooms and Super Secret Rooms. This Blue Map is treated as a character ability: it does not appear in the item list, and it cannot be removed or replaced by effects that change the passive items you already own, su...6.6k downloadsupdated 12 d ago
- Every item is X (but mine)by patczuchThis mod changes every item in the game to be the same item. Works on normal item pedestals, devil deals, shops etc. Works with vanilla and modded items. Please use Mod config menu to enable the mod and choose the item ( ). You can also configure if the key pieces, polaroid and negative should be...6.6k downloadsupdated 4 y ago
- Greed Mode Improved Legacy ***ONLY WORKS WITH AFTERBIRTH +***by SkollieW A R N I N G! --------------------------------------- This mod is NOT for Repentance. This is the legacy version of the mod for people that are still playing Afterbirth + or people that are going back to Afterbirth + to play mods that haven't been updated to work with Repentance yet. If you want...6.5k downloadsupdated 7 y ago
- better mom's braby 76561199505819505milf mom's bra6.5k downloadsupdated 21 mo ago
- Chaos Diceby kittenchillyAdds a new type of Dice, the Chaos Dice! This dice is like D6, but it can reroll into any other item from any other pool. The item can reroll into modded items as well! Supports EID. Chaos Dice (Active) "±?" Charges: 6 Quality: 4 Pools: Treasure, Greed Treasure, Secret, Greed Secret, Crane Game D...6.5k downloadsupdated 3 y ago
- Ironic Modby 76561199002593787Ironic Mod Nice to meet you, my name is Ironic, and I make bad videos on YouTube. One of the videos I decided to make was to put myself inside one of my favorite games: The Binding of Isaac! The result of this video project was the creation of this mod, the Ironic Mod. It started as a one-day pro...6.5k downloadsupdated 3 y ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

