Mods / Items

• UUncle Eli - Kick Bombs!by FilloaxUncle Eli ventures into the Basement! Eli is a player character, copypasted inspired from Uncle Eli in Crypt of the Necrodancer, who has three two main abilities: -He has infinite bombs. -He is immune to his own bombs. (now disabled by default, look further down for more info -And, last, but not...6.1k downloadsupdated 10 y ago
• DDeltarune Almond Milkby ADudeCalledLeoPractice some self-care! Changes the Almond Milk item to look like the healing milk featured in Chapter 1 and Chapter 2 of Deltarune. (NOTE: This mod does not make Almond Milk heal you.)6.1k downloadsupdated 5 y ago
• [[DON'T USE IT]Glitched Crown Slower Rerollby 76561198813796283(SPA) Este mod hace que los cambios de items hechos por Glitched Crown sean más lentos En vista de que alguien más hizo un mod mucho mejor que el mío, este dejará de recibir soporte, mejor usen este otro (ENG) This mod makes Glitched Crown's rerolls more slower In view of the fact that someone el...6.1k downloadsupdated 4 y ago
• NNeco-Ark coinsby 76561198833945718This mod is created for all true connoisseurs of Neco ark The mod changes all the usual models and coin picking sounds to the screams of Neco ark and her head This mod will appeal to everyone who likes to play in conjunction with other modifications related to this topic, for example, Isaac's rep...6.1k downloadsupdated 2 y ago
• CChargin' Targe instead of Marsby 76561198825922892Changes Mars to be 200% more scottish6.1k downloadsupdated 5 y ago
• BBook of Genesisby nickTHE BOOK OF GENESIS Adam and Eve Type: Active Cooldown: 4 Effect: Summons a male and female familiar for the room. Pools: Treasure, Shop, Library, Angel The Book of Genesis is an active item that summons two familiars from a specific pool to fight for you until the end of the room. This can be es...6.1k downloadsupdated 10 y ago
• FFast IV bag, Portable Slot and Kamikaze!by ☢ Nato Potato ☢Very simple. The cool-downs for IV bag, Portable Slot Machine and Kamikaze! are drastically reduced, allowing you to use them more quickly, you can even just hold the button in and they will be used repeatedly. (it works without affecting the players damage cooldown so you will still be protected...6.1k downloadsupdated 6 y ago
• FFour Souls Bombsby 76561199058109437Resprites bombs and troll bomb to resemble more of that of the fours souls cards. This includes all standard bombs and some slight tweaks to a few others. (does not change any bomb item sprites) THEIR EYES GLOW IN THE DARK HOW COOL IS THAT? Changes: -Bomb pickups and costumes -Giga bombs -Mega Tr...6.1k downloadsupdated 3 mo ago
• TTBoI: Radbirth [NUCLEAR THRONE]by majoThe Binding of Isaac: Radbirth is a mod that was made for Afterbirth in 2016 by majofps and EthanTheLion. Over the past week, it has been ported over and updated for the new DLC, Afterbirth+! Radbirth's Features: - ALL NEW Nuclear Throne characters - ALL NEW Challenges - Nuclear Throne themed ite...6.1k downloadsupdated 10 y ago
• LLoud Ni#ra Over Larynxby 76561198345921126Simple mod that replaces the Larynx scream with Loud Ni#ra. I cant make videos for this kind of stuff since my computer cant handle it, but Im sure you can imagine what it sounds like.6.0k downloadsupdated 5 y ago
• AAstra Mod 2.0by magicant tax collection agencyIntroducing Astra, a child from a distant world. Repentance support only. Update 2.0 - 17/10/22 The 2.0 update features a complete rewrite and partial redesign of the mod in order to make it less buggy, better looking and more fun to play. See the updates tab for the full list of changes. Adds tw...6.0k downloadsupdated 4 y ago
• FFixed Guaranteed Start [REP+]by 76561199054343421This is a fix/remake of the original Guaranteed Start. Any advice let me know! Features: - Replace the item ONLY in the first Treasure Room of the run *you go in* (that means u can skip for planetarium) with a 3 or more quality item. - It works with Greed Mode :D (read below) - Now it works with...6.0k downloadsupdated 4 mo ago
• TTBOI; Beyond - Repentant Incubuddiesby Ug-QualtothHello fellow isaakers, this is the Incubuddies Mod, now updated for Repetance!!! (or rather,, remade?! since all the sprites are brand new!! ahahah) SO, what does this mod do???!! Welp basically, every time u take an incubus, they will have the appearance of the character that you have! if u have...6.0k downloadsupdated 5 y ago
• MMario 1-1 In Isaac!by 『Sora』Adds Mario's first ever platforming adventure level to Isaac! This isn't a rom, it's Mario recreated using the base Isaac engine and physics. You can jump, shoot tears, bounce on enemies, collect mushrooms, and everything in between. Implemented as a separate character named Mario that you play as.6.0k downloadsupdated 5 y ago
• NNecromancer Costume(Rep+)by 76561198411462825When I looked through the newest patch notes, I saw a new transformation, and I said, "Where is it? Where is the new transformation costume?" but Edmun Mcmuffin preferred not giving it a costume, so this mod is for people like me who wanted a new costume for the new transformation in the game. Ha...6.0k downloadsupdated 14 mo ago
• MMaggot Petby 989fox989Tired of your boring old pets? Want something new and exciting in your life? You should get a pet maggot! Just feed him poop and watch him shoot tears! Occasionally he'll even fart and get diarrhea! Feed him a good variety of poop and watch him go! Red Poop: Poison tears, red diarrhea damages isa...6.0k downloadsupdated 5 y ago
• PPennies Into Zlotyby HydrantThis is a meme mod. This mod changes the cents into Polish Złoty. Sprite changes include: -Penny into 1 Złoty; -Nickel into 5 Złoty; -Dime into two 5 Złoty pennies; -Double Penny into 2 Złoty; -Lucky Penny into 1 Złoty with added green sparles; -Golden Penny into a złoty 1 Złoty (I am so funny);...6.0k downloadsupdated 20 mo ago
• [[ModConfigMenu]start with optional itemsby MerlinSpawn optional items randomly in first room on first stage. 在首层初始房间随机生成多选一道具[可以配置]6.0k downloadsupdated 4 y ago
• TTech Lby fedewNew passive item: "Tech L" - Electric shots! -Hitting the same enemy 5 times will spawn a lightning above it dealing 6x your damage, and burning them for a few seconds. -Also spawns a fire where the lightning hit -Appears in treasure rooms (can also show up in boss rush and greed shop) -Adds a co...6.0k downloadsupdated 5 y ago
• MMonster Mysterious Liquidby 76561199025304094Give the energy.5.9k downloadsupdated 13 mo ago
• MMisc item respriteby 76561199149887702A small mod that resprites a few random items, namely; Bob's rotten head delirious steven the poop mom's knife the inner eye lemon mishap ipecac dr. fetus and epic fetus torn photo head of the keeper proptosis and more?5.9k downloadsupdated 5 y ago
• GGreedy Limpetby 26 years of gooning laterCovet thy neighbor. The Greedy Limpet is a new passive item that loves coins! Every time you pick up a coin, the limpet gets a little more excited - granting you a small stat upgrade. Larger coins grant larger stat bonuses. If the limpet gets too excited it'll jump out of its rocky shell, resetti...5.9k downloadsupdated 5 y ago
• EEpic Fetus to Megumin's Hatby Kaiser Kaddu III.This mod changes the Epic Fetus costume to Megumin's hat and Eyepatch from KonoSuba!5.9k downloadsupdated 4 y ago
• MMagic Expandedby dpower12Do you want more magical stuff in Isaac? Ha-ha, this is just a nerdy mod that adds Magic The Gathering cards into Isaac. Magic Expanded adds currently: 4 new collectibles 16 new Magic Cards Full English Encyclopedia and EID support Coding: dpower12 Sprites: Sipher Nil Voiceover: The Owl Workshop...5.9k downloadsupdated 15 mo ago
• MMama mega! is Warthog mind blown emojiby PEZMama mega! x warthog mind blown meme5.9k downloadsupdated 3 y ago
• SSynaesthasiaby XalumSynaesthesia (Synesthesia) The steam icon and first image are not completely accurate as to how the sprite looks, those do not follow standard procedure while the actual sprite does. The general concept is the same and the difference probably isn't noticable "In one common form of synesthesia, kn...5.9k downloadsupdated 9 y ago
• CCxRedix's Dice Respritesby CxRedixSimple mod that replaces all dice graphics to my own liking!5.9k downloadsupdated 12 mo ago
• CCard Printerby ☢ Nato Potato ☢The Card Printer allows you to turn spare active items into cards which retain their effects, basically you get a secondary active item like schoolbag, but it takes up a card slot instead of an active slot, doesn't need any charge and only works once. Just double-tap TAB (or whatever your map but...5.9k downloadsupdated 4 y ago
• HHeadcrabbed!by 76561199222029485Replaces The Parasite with a Headcrab from the Half Life Series. This is part of another resprite mod which you can find here: Check out my other mods! You might like them :D5.9k downloadsupdated 22 mo ago
• CCar from Garn47 over Guppy (REP)by 76561198845546389Greetings! Nitrox here with my first steam mod! This mod aims to replace everything Guppy in Repentance with Car from Garn47. IMPORTANT: As of now, I do not know if this mod will work 100% on Repentance+. As much as I'd like to, it seems the way graphics and text displays work has been changed. S...5.9k downloadsupdated 2 y ago
• CCHAINSAW MANby 76561199155657668this mod changes berserk to chainsaw man and little chubby to pochita5.9k downloadsupdated 4 y ago
• TThe Binding Of Doki Doki Afterbirth+by BenShyMaru(Obviously this contains DDLC spoilers) Well... one day I happened to do some DDLC sprites ... and in the end I decided to make a kind of "Mini mod" Things that the mod has at the moment (This version is very WIP): - 4 Characters (Normal Dokis) - 4 Repainted Items Things I plan to do: - 4 more ch...5.9k downloadsupdated 8 y ago
• BBrawler Beggarby ☢ Nato Potato ☢The Brawler Beggar loves to spar but won't do it for free, if you pay him 3 cents he'll give you a punch. You won't lose any health but he does hit hard enough to trigger your on-damage effects and a number of other possible effects, he also has a chance to give you an item as a reward for being...5.9k downloadsupdated 21 mo ago
• GGoth_Mommy.mp3by 76561198450700216Purely Cosmetic mod Reskins The Mother Boss, including Delirium Forms Reskins the Items: Moms Underwear Moms Heels Moms Bra Moms Eye Moms Contact Moms Coin purse Moms Perfume Moms Pearls Reskins Portaits: Moms Boss Portait Moms Nightmare 9 Moms Hand All of Moms Champion forms Moms Bra giantbook E...5.9k downloadsupdated 3 y ago
• SSorcery: The Assemblingby aeiouA trading card themed mod! The goal of this mod is to integrate a set of Magic: The Gathering themed cards into Isaac in a way that is not out of place or overpowered. WE'RE IN BOYS Edmund has added some of the cards from this mod to the game in the first official booster pack: I am so excited, h...5.8k downloadsupdated 10 y ago
• BBrother may i have some oats over Ascentby 76561199219910159Changes the voicelines from the Ascent to whatever this Pigs are Thanks to burialgoods for this masterpiece5.8k downloadsupdated 17 mo ago
• CCounter Cupby EstrogenGirl"Do deal with the devil." Coded by AstroPenguin642. Sprited by CatnipOverdose. This mod adds an active item to the game. It is based on the popular game that came out recently called Cuphead. Counter Cup "Projectile parry" - Press the spacebar while near a pink shot to parry it. - Parrying fills...5.8k downloadsupdated 9 y ago
• CConsistent Holy Beamsby padre ballHoly beams from Crack the Sky now look like the ones angels (Uriel and Gabriel) fire at you, and also like Revelation. Affects the following items: -Crack the Sky -White Pony -Breath of Life* -Holy Light It also works with the beams the Holy Eye enemy fires at you. *Doesn't change the four holy b...5.8k downloadsupdated 3 y ago
• TThe Serpent (+24 Unlocks)by Kerkel2 New Characters Have Appeared in the Basement! The Serpent aims to spice up the normal Isaac formula by making the player choose between 1 of 3 unique Blessings and 1 of 3 unique Sins upon starting a run. Blessings grant a modest benefit to help you along, and Sins provide a strong negative effe...5.8k downloadsupdated 3 mo ago
• [[AB+ TESTED ONLY] Nearsightedby HiHowAreYouNOTE: I have not updated any of my mods to Repentance. I'm not sure if I will or not. If I do, it'll be after I've explored the update enough, I don't want to get spoiled by testing mods. Poor Isaac needs his eyes examined... Its not normal to cry so much. New item: Nearsighted When an enemy take...5.8k downloadsupdated 8 y ago
• LLootboxesby SwiftStriker00Introduction The intent is to provide players with a sense of pride and accomplishment for acquiring different items. As for cost, I selected initial values based upon data from the main game and other adjustments made to gate off rewards before launch. Among other things, I’m looking at average...5.8k downloadsupdated 9 y ago
• Ssus black powderby sex haverReplace pentagram with amogus. Randomly plays an amogus sound effect when pentagram drawn5.8k downloadsupdated 3 y ago
• TThe Binding Of Nikoby 76561198925841301Explore new perspectives with Niko's mod! THIS MOD ONLY WORKS WITH REPENTANCE/REPENTANCE+!! The Binding of Niko brings the character of Niko from the video game Oneshot into a new world. The sun is a new active that makes Niko strong enough to defeat enemies. Featuring: 1 New character EID compab...5.8k downloadsupdated 9 mo ago
• HHoverboardby MundanePantherHoverboard Passive Item Grants the player flying and a small speed increase when they are out of combat. Part of the "Back to the Basement" mod pack. A mod collection for The Binding of Isaac - Afterbirth Plus Twitter - @rhysdee Web - www.rhysd.com5.8k downloadsupdated 10 y ago
• DDark Prince's Crown Shoots Diamondsby LeopardoThe Dark Prince's Crown item now shoots red diamond tears when it activates! It's always bothered me that this wasn't a thing, so I made it, and might as well share it for others who may enjoy it too. It includes compatibility with most tear variants (you can tell me if I missed one and I'll incl...5.8k downloadsupdated 5 y ago
• SStart with Glitched crownby BarjuhStart each run with Glitched crown Collection with all my Start with mods :5.8k downloadsupdated 3 y ago
• SStrawberry Milkby robotragePink Milk gives isaac extra short range diagonal loki's horns shooting pattern as well as a damage up and shot speed up.5.8k downloadsupdated 9 y ago
• NNeko Steven(&Ash)by 76561198815141965Absolutely essential mod, Steven but cat :3 ash too now I guess (Steven's delirium form) IF YOU READ THIS GO SUBSCRIBE TO THE PETRIFIED POU MOD5.7k downloadsupdated 5 mo ago

1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.