The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Edith Restoredby BrakeDude"But Lot's wife looked back, and she became a pillar of salt." - Genesis 19:26 The unused secret character from Antibirth has been restored and improved, with updated gameplay for Repentance! Features 1 new character unlocked by defeating The Beast. 14 unlocks for Edith's completion marks. Custom...5.4k downloadsupdated 2 mo ago
- The D3!by j.scott.jewellThe d3 is an active item that removes a random item from your character, and spawns an item in its place. The item spawned is chosen from the pool of the room you're in, so you can do things like toss garbage items into a Devil Room for an easy upgrade. The recharge time is only 3, so fans of zan...5.4k downloadsupdated 10 y ago
- NE MARCHE PLUS Le Binding Of Isaac Afterbirth+ French Versionby 76561198053733721Dernière MàJ: 01.01.17: v0.5 Grâce à la grande aide de FireInTheHope ( ), la traduction est quasiment finie! il ne reste plus que les bébés Co-op et le menu à traduire! Bonjour à tous! Je vous présente mon mod appelé Le Binding of Isaac! Je vais commencer par faire une traduction complète du jeu...5.3k downloadsupdated 9 y ago
- Low Tier God Tech Xby de'metrious gaylordreplaces tech x with some ltg stuff n things !!WARNING!! - if you have the animated item pedestals mod ( it will take priority over the ltg item pedestal, no this wont do anything drastic like crash your game (god forbid) but it will stop the ltg pedestal from showing :(5.3k downloadsupdated 3 y ago
- Lil' Mega Satanby XalumRelease the power of your rage with Lil' Mega Satan, a familiar with a very large, but low damage brimstone beam, which has a set length. Found in item rooms and as a Devil Deal this familiar is sure to spice up any play through5.3k downloadsupdated 9 y ago
- Start with Incubusby BarjuhStart each run with Incubus Collection with all my Start with mods :5.3k downloadsupdated 4 y ago
- Angelic D6by TechSecPLAY TOO MANY D6S!!!!!!! ( ) Angelic D6 is a 6-charge active item that rerolls any pedestal into the Angel Room pool... If used in the Devil Room, you will get a normal pedestal instead of having to trade hearts. And when the Angel Room pool is fully maxed out, it's basically just a D6 reskin lma...5.3k downloadsupdated 3 y ago
- Bocchi the Small Rockby 76561199103802488Changes Small Rock to Bocchi from the anime Bocchi the Rock! Works amazing with "Bocchi the Tinted Rock" : Bocchi the Small Rock!5.3k downloadsupdated 4 y ago
- KeySackby GoldFeniks"Why isn't there a Key Sack?" If you've ever asked this question or just want another way to get more keys this mod is for you! It adds a new familiar - Key Sack(Captain Obvious at your service) which drops keys every 4 rooms. Update: Add Triple Sack trasformation! Get Key Sack, Sack of Pennies a...5.3k downloadsupdated 5 y ago
- The Boys Modby 76561199844292366Requires Repentogon! Adds compound V! First Character Added: A-train Use Wavy Cap in the same room as Experimental Treatment. A-train: -You get a pocket item that allows you to dash at enemies -Timing the dash key on impact makes you dash multiple times!5.3k downloadsupdated 5 mo ago
- Mixed Boss Collection Part 2by GuilhermeThis mod is the second part of the Mixed Boss Collection, does to limitations of how many values a mod can save I had to split it in three mods, CLICK HERE for the part 1 and CLICK HERE for the part 3 it also features it's own menu config to change which bosses do you want. list of bosses include...5.3k downloadsupdated 10 mo ago
- Old Golden Chestsby 76561198399574382Brings back the old golden chest item pool: - Cricket's Head - Tammy's Head - Guppy's Head - Goat Head - Head of the Keeper - Bob's Rotten Head - Bob's Brain - Steven - Fate - Fate's Reward - Abel - Infamy - Sack of Pennies - Mystery Sack - Sack of Sacks - Bomb Bag - Blood Bag - IV Bag - Little B...5.3k downloadsupdated 5 y ago
- Definitive Homestuck Reskinsby peasThe creator of Isaac Flips You Off! brings you the Definitive Homestuck Reskins mod, now updated for Repentance! This mod includes: - Unique and colorful sprites for each Sign of the Zodiac - Unique and colorful sprites for each Planetary Sign - Additional sprites for The Zodiac, Loki's Horns and...5.3k downloadsupdated 5 y ago
- [REP/REP+] Lydia*by heehooShoutout to Ferpe (@IFerPe01 on Twitter) for the awesome thumbnail art! They do commissions!!! * WHAT'S UP WITH THE ASTERISK??? * This was intended to be another full-package mod like my previous project, but due to a combination of Isaac burnout + newfound employment, I don't foresee myself fini...5.3k downloadsupdated 18 mo ago
- Odds And Endsby ArgumODDS AND END(S) Odds And Ends adds a few new zany items to the Basement that are sure to spice up any run! INCLUDES EID, SAVE/CONTINUE AND UP TO 4-PLAYER COOP SUPPORT! ============================================= ITEMS ARE STILL BEING ADDED AND IMPLEMENTED! ======================================...5.3k downloadsupdated 5 y ago
- Revolver Challenge: Reloadedby 76561198856919759This mod adds an exciting possibilty to use power of guns in your well known old basement. Collect items and upgrades, take your aim at monsters with 30 deadly guns and shoot them with 15 types of murderous bullets! Main additions New challenge: 30 new weapons! (24 of them use bullets) 15 bullet...5.3k downloadsupdated 5 y ago
- [Repentance compatible] AlterTweaks - Devil's Reliquaryby LooksmaxxatonClavicularSalomogisDISCLAIMER: Thanks to KliPeH for verifying that the mod is in fact Repentance-compatible! Though I'm still not sure if I plan on updating my mods any time soon, this is probably my favorite one of the bunch, and I wouldn't mind going back to add new sprites or making some changes to old ones. Ori...5.3k downloadsupdated 9 y ago
- Taro Reverseby 76561199030932150This mod adds a new active item - Taro Reverse. When using Taro Reverse, it turns over the tarot card in the character's hand Item pool - secret, shop, greed shop5.2k downloadsupdated 3 y ago
- !Rebirth Items Vectorized ! No HUD [OBSELETE]by EMORYRebirth Vectorized! replaces all item sprites with rasterized vector art similar to that of the original Flash game, but with vibrancy of Rebirth's sprites. New art for all of Isaac's items! Check out www.cormacillustrated.com/ for a gallery of all the artwork Modded items may be invisible and ne...5.2k downloadsupdated 4 y ago
- Whatsapp black powderby 76561199087745195It draws on the floor thw Whatsapp logo instead of the pentagram. That's it.5.2k downloadsupdated 5 y ago
- Spamton's dealmaker over 20/20by 76561198336913373Just replaces the 20/20 with Spamton's Dealmaker Old ver:5.2k downloadsupdated 5 y ago
- Da babyby 76561198448429576Basically a resprite of dry baby. Dababy. very funi! bottom text5.2k downloadsupdated 5 y ago
- Item Expansion Pack 1by KyoZMItem Expansion Pack 1 Item: "Mirror Of Sorrow" Description: "Return to the sender" Effect: On impact with enemy bullet, it will deflect the bullet back at the enemy. Scales with the player stats Item: "Lesser Key Of Solomon" Description: "Grimoire of the beast" Effect: Gives you a battle-riented...5.2k downloadsupdated 10 y ago
- The Binding of Deltaruneby Lancet The PhantomIntroduction: Ralsei and Susie from Deltarune join Isaac's basement! This my first ever mod, I made it for personal use and for an event held by Benny. And i decided to share here in the workshop! This mod is a work in progress, and Sanio will be helping me develop it! he is an official contribut...5.2k downloadsupdated 7 y ago
- Holiest Mantleby TwitchTheNimbatThe old sprite for Holy Mantle was always "okay", but it never really popped like it should for an item that was always so pog to see (especially for characters like the lost). So I decided to give it a bit of a makeover worthy of its legendary status. This is my first ever mod for Isaac, so I ho...5.2k downloadsupdated 5 y ago
- Chaos Buster (Undertale Brimstone Mod)by 76561198378853237This mod changes Brimstone into a Chaos Buster (Weapon Used in the True Pacifist Final Boss) 2nd Brimstone synergy is changed into a Gaster Blaster, and other Brimstone-related items are changed too. This mod is compatible with (Animated Items) Version without the costumes :5.2k downloadsupdated 21 mo ago
- Health and pickups pack (no cap items)by ☢ Nato Potato ☢This is a version of the health and pickups pack which does not include any of the cap changing items and as such does not require the no cap mods (though it does still work with them) Health = Power: +0.2 damage per full red heart, +0.1 damage per full spirit/black heart. Auto Resupply: +5 coins...5.2k downloadsupdated 8 y ago
- It's Going Down Now for Good itemsby PeridarrenDISTURBING THE PEACE, LOOK INTO MY EYES The Specialist dance but instead it uses It's Going Down Now from Persona 3 Reload. DROP VERSION RELEASED HERE If you wish to use it with Reaction Port Pack instead, someone made a mod that adds both the normal and drop version as an option with Mod Config...5.2k downloadsupdated 20 mo ago
- Delirite's Chamberby PixelPlzA Super Secret encounter has appeared below… This mod adds a unique fight against Delirite, a miniboss that can be found in Super Secret Rooms within the Caves and beyond. This special room variant has a chance to replace a normal Super Secret Room, and can only appear once per run. Placing 2, ra...5.2k downloadsupdated 16 mo ago
- Runic Tabletby 76561199101563685Runic Tablet This mod adds a new item to the Shop and Curse Room pool: The Runic Tablet. Runic Tablet spawns a random rune when picked up, increases the chance of runes appearing as room-clear rewards, and it adds an extra effect to every Rune and Soul Stone. Rune Buffs This mod features addition...5.2k downloadsupdated 2 mo ago
- Bad EGGby PantherboatGlitch Reroll! Introducing the Bad EGG!!! Visit your local room to find this item! Use it on your favorite pedestal it will turn into a glitch item, just like your best friend TMTRAINER would. Experience 6̴͉̕4̶̂ͅ3̴̯̂0̸̯͘4̵̢̋6̷̞͝0̵̻̑4̷̬̍ combinations of effects, and let the chaos unfold! Every tim...5.1k downloadsupdated 5 y ago
- Better Tainted Bethany / Lemegetonby rvstyEver had an annoying Lemegeton wisp of something like Soy Milk or Tiny Planet ruing your blast of a run? With this mod, this could be fixed! For a penalty of 1 damage you can get rid of any wisp you don't want to see and keep enjoying your run! Now when you have at least 1 Lemegeton wisp, a hand...5.1k downloadsupdated 4 y ago
- custom starting items [REP]by AliceShiki's Alt AccLets you customize the starting items for each character (except modded characters) by using Chifilly's Mod Config Menu. You can set 3 items and 1 trinket per character, the mod doesn't deal with pickups like coins or cards and doesn't affect 'hidden' items like Lilith's incubus, Lost's Holy Mant...5.1k downloadsupdated 5 y ago
- Lil Vis (New Familar)by ALTB0neNew familiar: Lil Vis! It follows Isaac and fires blood beams when enemies are in line of sight. It loads and shoots, just like the original enemy. Update 2.0: You can upgrade Lil Vis by collecting it multiple times! (2x = Double Vis, 3x = Scarred Double Vis) Update 2.1: Now compatible with Exter...5.1k downloadsupdated 5 y ago
- Binding of Nekos Redux (Repentance Support!)by SlemtemThere is no competition! You won't find any better cat girls to enhance your Binding of Isaac experience with. All characters besides Eden, Black Judas, The Lost, and The Forgotten are now gorgeous nekos. You'll really enjoy this amazing sprite work with the healthy balance of subpar starting ite...5.1k downloadsupdated 3 y ago
- LostD4by OttomatedThe D4 is useless with The Lost because it rerolls your Holy Mantle! Now, you can D4 all you want and you'll still have the effect!!5.1k downloadsupdated 10 y ago
- There's More Bugged Options at the Start!by prgoldfishFork of There's A Bit More Options at the Start! ( ) to make it buggy again. Bugs Features include : You can pick all 4 items The first treasure room does not disappear The items also spawn in Downpour I The items also appear in the Ascent5.1k downloadsupdated 6 y ago
- Security Blanket (Booster Pack #5!)by RatlahSecurity Blanket is now an official item in the game. Thank you all so much for the support! --- Security Blanket “You feel safe.” Shop pool -Upon pickup, Security Blanket will heal one red heart and give one soul heart. -While in boss rooms, you gain the Holy Mantle effect. --- Having trouble ho...5.1k downloadsupdated 9 y ago
- Cricket's Kittenby bethanw10Repentance Compatible Adds a new familiar item based on Cricket. Fires tears which will split into 4 on contact, like the effect Cricket's Body gives to the player's tears. Vanilla Synergies Counts towards Conjoined transformation Compatible with Baby-Bender Compatible with Forgotten Lullaby Comp...5.1k downloadsupdated 5 y ago
- Sheep Headby bethanw10Repentance Compatible When you kill an enemy, all enemies of the same type are damaged5.0k downloadsupdated 5 y ago
- Dog Whistleby ☢ Nato Potato ☢With the Dog Whistle trinket those pesky little bums can be brought to heel. After entering a room your bums will wait patiently by the door and will not move until you press CTRL (or swap button on controllers), pressing CTRL again will make them stop. The first bum you get in a run will drop th...5.0k downloadsupdated 22 mo ago
- Tough Gloveby NickSquigglesTired of running into Mimic Chests in a hurry? Worry no further! Holding the Tough Glove trinket means you won't take damage from Spiked & Mimic Chests :D All feedback welcome5.0k downloadsupdated 10 y ago
- Just Some Blessingsby Valvola_88Tired of Curses? This mod adds a small chance upon entering a not cursed floor to be blessed, giving the player a powerful effect for the floor. A bless icon is present to show the current floor blessing. Blessings List Blessing of Options - Gives Options, More Options Options? and Duality for th...5.0k downloadsupdated 5 y ago
- Color Zodiacby +*. Sayori .*+Just a simple mod to give colors to the zodiac items, each item has a color related to the function of it.5.0k downloadsupdated 10 y ago
- Universal Item Poolby TuddywutwutMixes all item pools. Meaning you can find Devil Deal items in your item rooms and Bosses can give you Shop items. It's how Chaos should function. Also effects Greed Mode. The game currently crashes if you attempt to use this mod with Tainted Cain.5.0k downloadsupdated 5 y ago
- alt. My Shadow sprite!by ViscerA5.0k downloadsupdated 5 y ago
- Basil, the Fool for Christby IrbynxExploration and melee oriented high risk/reward character. Adds 2 items and 1 character to the game: Fool for Christ "You feel curious!" * 0 - Fool cards have a chance to spawn each time you enter a new room (scales with luck) if you don't have one on the current floor already. * 0 - Fool cards h...5.0k downloadsupdated 9 y ago
- The Priestby OnyxThe Priest is here to reedem God's name from Mom, who has been deceived by the Devil. He heard his prayers and now his tears are his only weapon! The Priest does not shoot, instead he has a giant tear orbital. The mod also contains Prayer, an item that turns your tears into an orbital and prevent...5.0k downloadsupdated 8 y ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

