Mods / Items

• EEye Witnessby ☢ Nato Potato ☢The all seeing Eye Witness is a familiar that can reveal secrets to you. Including dungeons, black markets, secret rooms, surprise boss rooms (like mid-bosses, greed in shops or krampus in devil deal rooms), as well as identify an item when you have curse of the blind and warn you if you have low...8.9k downloadsupdated 22 mo ago
• MMinecraft Tainted Cainby Modern Strange CowboyTainted Cain but Minecraft style. I spend waaaaaay to much time redrawing every single costume to fit his block head Also changes the bag of crafting into a crafting table, enjoy8.8k downloadsupdated 5 y ago
• EEpiphora Buffer Frames (Old)by 76561198855158338THIS IS THE OLD VERSION OF THIS MOD! Go download the new version! Video footage provided by Namie Kuningham! They also have a video detailing every item this mod affects here:8.8k downloadsupdated 4 y ago
• SStart with Godheadby BarjuhStart each run with Godhead Collection with all my Start with mods :8.8k downloadsupdated 4 y ago
• CCrash Bandicoot - Aku Aku Holy Mantleby CrashpunkOOGBAGAH! It is I, Aku Aku! My duty is to protect you! Replacement for the Holy Mantle and Holy Card. Mod Config Menu support. Choose between Aku Aku, Uka Uka and Lights Out/Jaws of Darkness Aku Aku!8.8k downloadsupdated 9 mo ago
• GGuwah Greaturesby GuwahavelThis mod is for Repentance Have you ever felt a desire for something more to your floors? More intrigue? More greatures? More challenge? Then this mod is for you! This mod adds: -17 new enemies to test your mettle! -Over 1500 new rooms, spread across every floor in the game! -2 new items! -Surpri...8.7k downloadsupdated 4 y ago
• MMore Treasure - Better Co-op!by BigrojobearPlay co-op with your friends and don't get item starved. Extra items have been added to treasure rooms, planetariums, boss rush, angel rooms, devil rooms with some other bonuses along the way.8.7k downloadsupdated 5 y ago
• CCrow Headby ☢ Nato Potato ☢Crow Head is a passive item that has a chance of spawning a half soul heart when you kill an enemy. At 0 luck, there is a 3% chance of spawning a half soul heart and it increases by 1% for each 3 luck you have, capping at 15%. (e.g. 9 luck = 6%, 18 luck = 9%, 27 luck = 12%, 36 luck = 15%) You can...8.7k downloadsupdated 8 y ago
• BBanana Tearsby ErflyBanana tears! This simply adds an item to the game that's a reskin of the pupula duplex. (Potassium Duplex) It doesn't replace anything, nor does it function all too differently. (Hopefully) Code for replacing the tears is based off of Scayze's Cystinosis Art is done by Stewartisme8.7k downloadsupdated 10 y ago
• TThe Binding of the Spire Englishby 76561198355620741这是英文版本 中文版请在创意工坊找同名MOD tips:PC Only Slay the Spire MOD 34 new items! 44 new cards! How to Play： WSAD Move Mouse Left : Attack Mouse Right : Use Card/Click Button/ KeyBoard :1/2/3/4/5/6 Use Card turn off enemy'smark:input "target" in console right click to pick starting bonus right click to pick s...8.7k downloadsupdated 8 y ago
• IItem Icons on Character Selectby 76561198375403876A quick mod to replace the icons on the character select screen with the actual item icons. Might require a game restart to fully apply the changes Not compatibl with other mods that edit the character select screen8.7k downloadsupdated 4 y ago
• [[AB+] Hericideby BennyA New Character: Hericide! "Hermes, a skittish goat from a small farm, has been cursed by the eyes of fate and is now known as Hericide. Hericide's bloody red crossed eyes can see into the crossroads of the spirit world, and the fates of any living person he sees. Overtime his black tears stained...8.7k downloadsupdated 6 y ago
• RRepentance Negative-by 76561199094088506We present to you a mod that is not of the best quality, but with interesting jokes! Also, dig through the mod files, you never know what might be hiding there... Repentogon required! Adds 2 new character! Adds 30+ new items! Adds 5+ new trinkets Adds 1 new card, pill and new pickups and machine...8.7k downloadsupdated 8 mo ago
• RRib Cageby ☢ Nato Potato ☢The Rib Cage is a passive item that gives you 1 bone heart and makes you take red heart and soul heart damage before bone heart damage, allowing you to keep the extra red heart space from bone hearts until you get some more red hearts. Works well with the forgotten. (does nothing on sacrifice spi...8.6k downloadsupdated 5 y ago
• HHot Heelsby RyouHave you gotten sick yet of all the advertisements about cool guys going around at ludicrous speeds in their fancy cars? No? Neither have we! Introducing the one and only Hot Heels! This item will make you go super fast, so fast in fact, that you'll be leaving your own personal fire trail that da...8.6k downloadsupdated 10 y ago
• IItem Pool Rework Modby Dr. Monty(If you have any questions about this mod, check out the QNA under the description!) Does walking into a devil deal, only to see Multidimensional Baby and We Need to Go Deeper, give you clinical depression? Are you sick of seeing items like Duality and Mom’s Coin Purse appearing way more often th...8.6k downloadsupdated 3 y ago
• BBalanced Starter Choicesby 76561199114159195Tired of walking into your very first Treasure Room and getting stuck with a single random item? Balanced Starter Choices replaces the lone starting pedestal with a configurable set of item choices, just like the "There's Options" pickups — pick one, and the rest vanish. WHAT IT DOES - On your fi...8.6k downloadsupdated 3 mo ago
• TThe Cursed and Brokenhearted - "I Never Forgot You"by 76561198813288416Notice I will not update this any further, I just readded it so people can play it Prerequisites for the best experience StageAPI - For the new bosses and such MMC - For the new music in the game! MinimapAPI Immortal Hearts from Team Compliance - For easier new personality unlock! EID - descripti...8.6k downloadsupdated 3 y ago
• TTweaked Duality spriteby ViscerATweaked sprite for Duality. It doesn't change the costume, but if that is something you'd like to see, don't hesitate to let me know! Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your con...8.6k downloadsupdated 6 y ago
• SStart with C Sectionby BarjuhStart each run with C Section Collection with all my Start with mods :8.6k downloadsupdated 4 y ago
• GGood Dealsby 76561198865227624Will improve deals with the devil and angel, increasing the chances of getting the highest quality items 3, 4 and Guppy-related. Also changes predictions in fortune tellers. Thanks for translations and ideas Gusa and NixSaji The code for predictions was taken from the mod Antibirth Fortunes Updat...8.6k downloadsupdated 4 y ago
• TTear Helpersby ☢ Nato Potato ☢The Tear Helpers item has a chance to turn one of your fired tears into an orbital familiar that damages enemies and synergizes with your tear effects. The familiars will only last a few seconds but their damage scales with yours (they deal 35% your damage per tick) and their movement speed scale...8.6k downloadsupdated 5 y ago
• AAlways Opened Secret Roomsby Joe BidenAlways opened secret rooms by starting with X-ray vision.8.5k downloadsupdated 5 y ago
• AA Bushel of Blessings!by PoondaedalinSupport for EID in English, Russian, and Ukrainian! Eden's Blessing is cool and all, but what if there were more of them? Adds 16 new "Blessing" items: one for each other normal character! Each of these blessings can be found in the Treasure Room item pool. - Isaac's Blessing ["Your future is in...8.5k downloadsupdated 3 y ago
• DDual Item Roomby Xixi!!! This mod is not compatible (yet ?) with Repentance !!! Mod that allow to have and pick up 2 item in treasure room, good for coop with the true coop mod. Mod qui permet d'avoir et de ramasser 2 items disponible dans les treasure room, pratique en coop avec le mod true coop.8.5k downloadsupdated 8 y ago
• CCandle Indicatorby 76561199049581887a mod to indicate the 5 levels of the item Paschal Candle, enjoy8.5k downloadsupdated 3 y ago
• CCereal Cutoutby nick***This mod was added to the game, and is now redundant. Thank you everyone for your support.*** CEREAL CUTOUT Allow 6 weeks for delivery Type: Active Cooldown: 4 Effect: Makes a random item in the shop free. Pools: Treasure, Shop, Beggar Cereal Cutout is an active item that makes a random item i...8.5k downloadsupdated 10 y ago
• BBasic Shop Itemsby ErflyPay more to get more in the shop! This mod simply adds some collectibles to the shop that count as multiple pickups for 15¢ each. Ever enter a shop with tons of money, but they only sell one key and you need five? Or you're low on health and only a single heart is being sold? Have no fear, becaus...8.5k downloadsupdated 10 y ago
• BBattle Cats Resprite Packby 76561198873571986*NEW UPDATE!!!* Do YOU like Battle Cats? Are YOU a complete loser? Well this is the mod for you! This mod resprites a bunch of items and a few pickups to be Battle Cats themed, and changes the costumes for them as well. I might make an updated pack in the future with more complicated changes (lik...8.5k downloadsupdated 10 mo ago
• Bbetter crowns 2.0by 76561198876704734this is an improved version of a previous mod I've made, now containing slightly improved sprites and diamond tears for Dark Prince's Crown baked in.8.5k downloadsupdated 4 y ago
• [[REUPLOAD] Aladar's Mushroom Items Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...8.4k downloadsupdated 17 mo ago
• SShamrock Malphite Over Gnawed Leafby Adadmek8.4k downloadsupdated 21 mo ago
• SSticky Fingersby ☢ Nato Potato ☢This mod adds Sticky Fingers into the game, which when held causes Isaac to instantly pick up every collectible item in the room, including active items, sometimes it can be a pain, however it does allow you to steal from shops and devil deal rooms. The mod comes with one challenge, "ALL the acti...8.4k downloadsupdated 5 y ago
• SSausage but Sandvichby 76561198804757721Sausage but now is sandvich from TF2 *very funny* This mod is a reskin and rename of the original item Sausage The original costume was change too and when you pick up make a short and funny sound effect Made using the code from: • • Maybe at some point I'll update the mod and make all the charac...8.4k downloadsupdated 3 y ago
• DDataminer Descriptions CNby 76561198811272757为数据破解生成的错误道具显示中文效果描述，基于 EID 中文数据库优化显示。8.4k downloadsupdated 4 mo ago
• IInfini-Chest!by Dracula joeThis mod adds an item and a trinket, the Infini-Chest and the Incomprehensible Key! The Infini-Chest (treasure room pool, shop pool (0.5 weight)) is a 4 room charge active item that spawns a special locked chest named the Infinichest and consumes 1 key. Infinichests spawn 5 pickups OR an item fro...8.4k downloadsupdated 4 y ago
• BBeckyMod [Tainted Update]by 76561198992641386Play as Becky and Her Ghost Friend, Characters originally made after an Art Challenge Becky: You cannot shoot tears, your only attack method is a really bouncy ghost friend Devil and Angel Deals are swapped too Tainted Becky: Use Many different Spells, randomized each Run Acquire more through Dev...8.4k downloadsupdated 2 mo ago
• MMonster Energy over Mysterious Liquidby labubuMostly just a test. Gives the roid rage costume combined with the glow of the old mysterious liquid.8.3k downloadsupdated 5 y ago
• FFaith's Rewardby DaGammlaDo you have a bad Computer? Do the fireworks produce lag? Just press "F1" and you're save! CAUTION ! This mod is possibly not compatible with others but Works perfectly with True Co-op Content : --Dynamic Boss drops-- Bosses have a chance to spawn Boss specific items like Mask of Infamy -> Isaac'...8.3k downloadsupdated 8 y ago
• DDeath's Door Stopby corndogcopWhat does this do? Death's Door Stop is a trinket that lets you return to Devil/Angel Rooms whenever you want! While held, it prevents all doors to Devil and Angel Rooms from disappearing once they've been opened. Not only that, but teleporting into a deal with a Joker card, Red Chest, etc. will...8.3k downloadsupdated 4 y ago
• HHappy Shroomby ☢ Nato Potato ☢Happy Shroom is a custom passive item (based on the vinesauce 'vineshroom') which triggers an unusual transformation. Once transformed all mushroom enemies will become friendly and any static mushrooms you touch turn into friendly mushroom helpers. These happy little guys are helpful but they are...8.3k downloadsupdated 5 y ago
• OOhyo - Character & +15 New Items [AB+]by AgentCuccoA brand new and unique character! Use your Blood Gauge to store red hearts and use them as charges, as well as becoming a sharpshooter to land critical hits on enemies. Use over 15 brand new items to help you traverse the basement! THIS MOD IS UNTESTED IN REPENTANCE Features: - A brand new and un...8.3k downloadsupdated 6 y ago
• EE-42: The Automaton [REP]by palookaE-42 is finally in her own standalone mod! Check out the original mod here: New Character! E-42 is a close-range, high-DPS character with a penchant for gargantuan bursts of explosive damage. She comes with +500 custom costumes and a menagerie of unique synergies; Using the Old Wardrobe or Old Wa...8.3k downloadsupdated 3 y ago
• Ccool brimstoneby 76561199060899854我给硫磺火画了个新贴图，让硫磺火看起来像在燃烧一样 Give your brimstone a new texture to make it cooler!8.3k downloadsupdated 2 y ago
• AAlt Path + Mother in Greed Mode!by 76561199034036813With the 1 year anniversary of Planetariums in Greed Mode coming up, I knew I had to return to my roots and make another greed mode mod. So, I present to you: The Alt Path in Greed Mode! Yes, I know this has been done before (twice in fact) but the original mod had 3 main problems that this mod f...8.3k downloadsupdated 4 y ago
• SSuccubus is sus 😳by 76561198974383566Just simple mod which changes succubus8.3k downloadsupdated 5 y ago
• BBeiraby Fury McFlurryBeira as a character Beira starts the game with 2 hearts and a broken heart. and her veil, which allows her to push enemies away or even freeze them to death. Double tap your firing key into a direction, and Beira's special attack is performed. Beira's curse A small timer is present; this timer i...8.3k downloadsupdated 5 y ago
• DDusty Box of Friendsby ErflyAn old friend. Functions just like the pre-nerf Box of Friends, but doesn't replace the regular Box of Friends. This means that it takes two charges rather than four to use! Lilith will not start with this item. This item can be found only in secret rooms.8.2k downloadsupdated 10 y ago

1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.