Mods / Items

• Ttainted keeper start with birthrightby 76561198367122054Very simple. Tainted Keeper now starts with birthright.3.8k downloadsupdated 5 y ago
• AAlexelcapo Modby TremensMod de Alexelcapo. Este mod contiene: Nuevo personaje: Alexelcapo 1 Item activo 2 Items pasivos 1 Familiar(Halfonso) 1 Habilidad especial del familiar Sonidos de muerte, daño y uso de item activo. Y muchos de sus memes. Descripción de los items: -Falta daño: Al agarrarlo reduce el daño del person...3.8k downloadsupdated 9 y ago
• MMom's Moleby Mozzie"Burrowing tears + shot speed up" Adds a brand new passive item to the Treasure Room pool! Shot speed up + slight range down. Isaac's tears now burrow underground at the end of their range. After enough have been burrowed, they'll all reemerge at once with combined tear effects. Now part of Straw...3.8k downloadsupdated 9 y ago
• BBad Ice Cream Cube Babyby 76561198981246087Remember Bad Ice Cream? Now you can have the strawberry flavour as a companion while you struggle for life! also check out my other mod ^ ^ enjoy!3.8k downloadsupdated 2 y ago
• WWhistle Piece - Yondu's Arrowby Avid pooper pantI saw a Lazy Mattman video, where he mentioned Yondu from the guardian of the galaxys arrow. So I thought why not try, resulting in my first very simple mod. This mod introduces a new collectible item, "Yondu's Headpiece", an active item that spawns the Yaka arrow next to isaac. By using the item...3.8k downloadsupdated 3 y ago
• LLFG Psy Fly Title Screenby SprSnpr_This mod is a combination of: BABY FUCKING PLUUUUM Psy Fly In Menu Please support the original mod creators and don't subscribe to this trash I've made (Grande if you're reading this I'm sorry lol) This mod was made by request3.8k downloadsupdated 5 y ago
• SStart with Trisagionby BarjuhStart each run with Trisagion Collection with all my Start with mods :3.8k downloadsupdated 4 y ago
• BBombastic_Flyby 76561199102149926This replaces the Sprited for BBF with the great Mista Boombastic Now with lil delirium reskin as well as an item pickup sfx The pickup name should be changed thanks to I Hope you enjoy!!3.8k downloadsupdated 2 y ago
• DDual Pistols over 2020by 76561198423405055I have a problem. On another note, This is my best one yet!3.8k downloadsupdated 4 y ago
• PPeppino Larynxby Apollo JusticeFor those like me that have been infatuated with Pizza Tower, I decided to make a mod that changes the Larynx sound effects to the funny Italian man's screams3.8k downloadsupdated 4 y ago
• HHector from OMORIby 76561198346397289This mod add beloved pet rock of KEL from OMORI. Unfortunately, you can't return Hector to Kel, so you can become his new friend! Change sprite for "The Small Rock" and "Rock Bottom" Сhange sprite for character with these items. Сhange their name and description. Add sound effect when picking up.3.8k downloadsupdated 3 y ago
• 110 cards packby 7656119880340664810 new cards have appeared in the basement! ·This mod adds 10 new cards with new effects to the game! Cards list: - God card *Effects: It has a 95% chance of giving you a coin and a 5% chance of giving you godhead *Spawn chance: 0.5% - Mirror card *Effects: Changes all your items (like D4) *Spawn...3.8k downloadsupdated 7 y ago
• AAntibirth for AB+ (and Repentance)by im_temDo not install this if you want to play Antibirth, go to antibirth dot com instead Antibirth was made by P.E.N.I.S team, not me or even better, get yourself Repentance instead of running this, dammit! ----- Antiborne is now real, even for Afterbirth+ (now also for Repentance!) Let's be honest, yo...3.8k downloadsupdated 4 y ago
• TTweaked Mom's Knifeby ViscerATweaked sprite for the legendary Mom's Knife. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading every sprite tweak separately, so that if you don't like some of...3.8k downloadsupdated 6 y ago
• TTelefraggerby DrakonnasThis mod adds a new item that lets you kill enemies by teleporting into them! Telefragger is an active item that instantly moves you a short distance in the direction you are walking in. If you happen to teleport into an enemy, they die! *Update* Teleporting into a boss does not kill it. Instead,...3.7k downloadsupdated 10 y ago
• TTelltale Heartby je suis une pomme de terre"One last chance" Adds one item to the game: The Telltale Heart! When you pick up this item you will be revived upon death with the health of The Lost, meaning you will die in one hit and get free devil deals! This revival happens after all other extra lives with the exception of Missing Poster a...3.7k downloadsupdated 9 y ago
• [[AB+ | Rep] Why Not Both?by zarat.usTired of choosing between option pedestals (like those in the alternate path, or those spawned by There's Options and More Options)? With this item, now you don't have to choose! Take them both!3.7k downloadsupdated 6 y ago
• PPure Nail Spirit Swordby ZyckroThe ultimate weapon of Hallownest has appeared in the basement! This is a resprite for the Spirit Sword item, changing its appearance to match the titular weapon from Hollow Knight. Enjoy!3.7k downloadsupdated 3 y ago
• TTweaked Blood Clot spriteby ViscerAIt's not just flipped sprite of Blood Clot. The thumbnail isn't 100% accurate, due to the updates I introduce after receiving feedback. You'll just need to subscribe to see how it looks :3 Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks yo...3.7k downloadsupdated 6 y ago
• VVVVVVV's Super Gravitron [Rep/Rep+/AB+]by JSGExpected an Isaac mod?....Late-March Fools!, it's VVVVVV's super gravitron but in Isaac. Ya, basically, just that, I remade an easier version of the VVVVVV's Super Gravitron as an AB+ mod challenge. How can I play it? Access the challenges menu and press tab, then look for "Super Gravitron". Make...3.7k downloadsupdated 4 y ago
• BBosses Unleashedby VideoGameNewsEver wanted to unleash the power of a boss onto your foes? Well LOOK NO MORE!!! Bosses Unleashed!!! This mod have over 90 NEW items that can be found in the treasure and shop rooms in both normal or greed mode. Here is the list of all new items. Enjoy! Larry Jr The Hollow Monstro Chub C.H.A.D The...3.7k downloadsupdated 10 y ago
• DDiamond sword over spirit swordby 76561198372192441Mod changes all spirtes for spirit sword to diamond sword from minecraft (also some sound effects)!3.7k downloadsupdated 4 y ago
• PPaper Isaacby Mode8fx• 10 passive items, 1 trinket, 1 transformation, and 2 challenges • Repentance and multiplayer support This modpack contains 11 badges from the Paper Mario series, all adapted to Isaac. It also includes a transformation that is activated upon getting 3 of these passive badges (or a combination of...3.7k downloadsupdated 4 y ago
• EEternal Flameby NiroEternal Flame This item gives you a damage up when you are close to a fire. The closer you are, the more damage you get. At the closest range it gives you +3 damage. In addition to that, each enemy you kill has 15% chance to turn into a fire (the fire can't hurt you). The fire that increase your...3.7k downloadsupdated 4 y ago
• Mmug momentby 76561198994914497certified mug moment reskin of jesus juice3.7k downloadsupdated 5 y ago
• BBetter Item Colors!by 76561198965961086Just a quick little mod I created that turns the bland red on devil deal items AND the boring blue Horoscope/Planetarium mn items into COOL fading colors! I don't care if you download it, only if this is they type of thing you like.3.7k downloadsupdated 5 y ago
• RRosaries Over Coinsby 76561198963408565Change "all" coins with rosaries Changed: All coin trinkets All coin pickups All Slot Machines got rosaries instead of coins A Quarte - Rosary Necklace A Dollar - Heavy Rosary Necklace Wooden Nickel - Wooden Rosar (Changed Kipper's HP temporarily removed)3.7k downloadsupdated 8 mo ago
• SStart with The haloby BarjuhStart each run with The halo Collection with all my Start with mods :3.7k downloadsupdated 4 y ago
• IImproved Key Piece Spritesby O_oChanged the Key Piece familiars to be the same colour-scheme as the golden door & reshaded the Key Piece item sprites.3.7k downloadsupdated 9 y ago
• EExtinguisher of Soulsby SprSnpr_Extinguish Their Souls!!! This is a mod that changes the sprites and sound effects of the Urn of Souls to resemble a fire extinguisher. That's all. Everything related to the Urn of Souls has been updated- except for one thing. Judas and Dark Judas' birthright gives them a unique sprite and effect...3.7k downloadsupdated 3 y ago
• EEye of Greed from Four Soulsby ViscerANow it looks more unique, and is also consistent with its Four Souls card.3.6k downloadsupdated 5 y ago
• HHoly Milkby RuzzyOnce upon a time, a preist grew soy using holy water. He then made it into milk. And it tasted... salty... Gives isaacs tears holy light, homing, spectral and piercing. Comes with a free damage down and tears up. My first mod, so feedback it greatly appriciated. PS. Yes, its supposed to be quite op.3.6k downloadsupdated 7 y ago
• TThe Binding of Pokimon Mystery Dungeon [Afterbith + Edition]by NarxThe Binding Of Pokimon Mystery Dungeon is a mod that turns Isaac's basement into pokemon mystery dungeon world, includes PMD levels, bosses soundtrack sound effects and much more... DOWNLOAD FULL VERSION HERE: mega. nz/file/yhEADZpa#X9R9MN2_tNITsbixkOxlmknccSU1cBjsD5GEUmaVbwI FEATURES: -Playable...3.6k downloadsupdated 6 y ago
• CCamo Undies to Patrick's Undies!by 76561199011749367Mom got Isaac new undies and he seems to like them! This awesome Patrick's pants give you so much swag that no one will ever dare to call you pinhead!3.6k downloadsupdated 3 y ago
• MMoxie's Kittenby bethanw10Repentance Compatible Adds a new familiar item based on the Moxie items from the Revelations mod. Moxie's kitten comes with a floating ball of yarn which will float around damaging enemies. If the ball gets close enough to the kitten she will bat at it making it to fly around faster and cause mor...3.6k downloadsupdated 5 y ago
• TTweaked Pandora's Box spriteby ViscerATweaked sprite for Pandora's Box. Now it looks like an actual box. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading every sprite tweak separately, so that if y...3.6k downloadsupdated 6 y ago
• [[Ab+ Only] Bugfixes and Improvementsby GuilhermeThis mod is a compilation of my bugfixes and improvements mods, it has a low priority so any mod should overwrite it, maximum compatibility! All following mods are already included in this mod, don't subscribe to them! (Bug fixes) Fixed Bandage Girl Body Fixed Peep/Bloat's eye hitbox Fixed 1 Boss...3.6k downloadsupdated 6 y ago
• LLazy MattMan (playable character)by 76561198881685834The worm, The myth, The lucky sun of a gun. LazyMattman is here to enjoy the content! But who knows the luck of what may happen next?3.6k downloadsupdated 2 y ago
• TTweaked Blue Candle spriteby ViscerATweaked sprite for Blue Candle. Now it's not just a recolored Red Candle. The flame also burns a bit lighter, to indicate that this is the more powerful one of the two Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see f...3.6k downloadsupdated 5 y ago
• Mmagic hatby WofsaugeMagic Hat is a passive item that removes the timers on Bossrush, Hush and Delirium, making these rooms always accessable after killing specific bosses. Itemidea provided by TheAverageJoey Features: - +1 Luck - Spawns Bossrush door after killing moms foot - Spawns Hush door after killing Moms hear...3.6k downloadsupdated 9 y ago
• LLittle Bishopby UdolfieLittle Bishop Little Bishop is a new unique familiar which looks like Bishop enemies. While in hostile rooms, it will target tears in it radius. Tears it target gain the "Lost Contact" effet and a laser connects the familiar to the tear. Synergies This familiar synergies with : BFFs : Lasers deal...3.6k downloadsupdated 5 y ago
• AAll Item Rooms Have 3 Itemsby mc phatPretty self explanatory, all item rooms now have triple the items, this includes item rooms, devil/angel rooms, shops and secret rooms3.6k downloadsupdated 8 y ago
• CColourful Zodiacby TabbyTaoThis Mod Changes The Zodiac Items Colours To Make Them look like the costumes in the game, also flips the zodiac item colours to fit more with the rest of the items, enjoy3.6k downloadsupdated 6 y ago
• BBozo (IN BOOSTER#1)by electoon*WE'VE BEEN ACCEPTED! THANKS FOR USING THE MOD!* Party time! +chance for a random enemy in current room to be charmed or have fear effect +chance that, upon taking damage, will spawn rainbow poop +1 soulheart +.1 attack --NOW AVAILABLE IN TREASURE ROOM, GREED, GREED TREASURE ITEM POOLS--3.6k downloadsupdated 10 y ago
• CCatalog (now in game as Keeper's Box!)by TremisUPDATE: This item is now functionally in the game as Keeper's Box. Item is now obsolete as a result but I couldn't be happier! Hope everyone enjoys this as a permanent part of Isaac! Item Description: A holiday-themed item that hearkens back to simpler times. It can be found in shops, libraries,...3.6k downloadsupdated 9 y ago
• AAudible Holy Mantleby DannyIsInHell ᑎᐱholy mantle got nerfed to only give invincibility for .5 seconds. This sucks because the visual reaction speed for most humans is around .35 seconds. This mod hopes to fix that by replacing the simple glass shattering noise with an earpiecingly distinct siren that is sure to be noticed. Since aud...3.5k downloadsupdated 6 y ago
• [[REP and AB+]touhou beggar and bumby 765611983818600013.5k downloadsupdated 5 y ago
• CConsistent Blood Colour [In Booster Pack 5]by XalumThis mod aims to make all of the blood on Isaac's costumes the same colour. Some sprites were als changed in other ways in order to better facilitate a merge with Real Cone Head, these costumes are marked with a "C" Costumes changed: Lazarus's read tear stains when he revives Lilith's blood stain...3.5k downloadsupdated 9 y ago

1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.