The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth items mods
Everything filed under items by its own author, ordered by how much it is used.
1,309 items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.3k items mods
- Crap-B-Gone!by 76561198391988105Guarantees that the item from the first treasure room will have a quality of at least 2. Works in Normal, Hard, Greed and Greedier mode. Alternate version for quality of at least 3: It's only meant to help do not quite as many R presses. It doesn't change, drain or affect in any way the pools or...4.1k downloadsupdated 5 y ago
- Menacing Drops (JoJo Reference)by 76561198964109815This mod is a JoJo Reference, it includes: - A resprite for the Knockout Drops item that turns it into the Menacing Drops (the effect is still the same); - A resprite of the fists that the item makes you shoot (they become Star Platinum's fists); - Menacing particles on every character on top of...4.1k downloadsupdated 21 mo ago
- Sad Heartby EstrogenGirlSad Heart "Be hearty" - For every red heart container you have, empty or full, you get a 0.25 damage up. Coded by AstroPenguin642. Sprite by CatnipOverdose. Costume and Thumbnail by TRPG.4.1k downloadsupdated 9 y ago
- The Darksign [REPENTOGON]by ChrisSor54REQUIRES REPENTOGON TO FUNCTION! The Darksign has appeared in the basement... This item grants you the curse of undeath, but at a heavy price. Upon death, Isaac will resurrect at the starting room of his current floor as a Soul, a fragile spirit who gains the powers of flight and spectral tears,...4.1k downloadsupdated 2 y ago
- Start with There's optionsby BarjuhStart each run with There's options Collection with all my Start with mods :4.1k downloadsupdated 3 y ago
- Overly Attachedby Lord HollowsOverly Attached - She's a head case! This pink fly loves to rest adorably on your head...but if an enemy is in the room, she chases after her new obsession! Once attached, the enemy is charmed until it dies. She'll go find a new friend, until there are no friends left, at which point she'll go ri...4.1k downloadsupdated 10 y ago
- Bloodstained Stigmataby ViscerAMore shading, and some blood at the bottom. Not much of a change, but I have always thought the stake should have blood on it, since it was implied to have been stabbed through someone's hands... If you think this one was pointless, don't hesitate to let me know :p4.0k downloadsupdated 5 y ago
- Fallen Feather & The Glutton's Fork Challenge!by Mozzie"Help from above!" Adds a brand new passive item to the Angel Room pool! Art and The Glutton's Fork idea and design by Aczom. Code by Strawrat. This mod uses a cropped version of the following sound effect from Freesound: "01543 flying dragon" by Robinhood76. Fallen Feather: +2 Soul Hearts. Every...4.0k downloadsupdated 9 y ago
- [AB+ ONLY!!!] Flysaacby peasTHIS MOD ONLY WORKS IN AFTERBIRTH+ IF YOU COMMENT ABOUT REPENTANCE COMPATIBILITY I WILL HURT YOU!!!!!!!!!!!!!!!!!!!!!! FLYSAAC returns from the titular Devil's Harvest MOD with a brand new kit, redesigned from the ground up! Take advantage of Flysaac's generous heart and conjure various flies dur...4.0k downloadsupdated 6 y ago
- Super Mushby NiroEdit: A version that works with Repentance: Super Mario Bros Mushroom in Isaac! This item replace all red heart pickups with mushrooms pickups. Each mushroom increase damage by 0.5 and also increase player size (it doesn't make player hitbox bigger). When you take damage (cursed door doesn't coun...4.0k downloadsupdated 9 y ago
- Fiend Folio [RUS]by Dick NukemFiend Folio Изменения внесены только в части переведенных строк для мода EID (External Item Descriptions) Как установить: 1. Скачать все другие необходимые моды, а именно: Fiend Folio: Reheated - 500 New Monsters! Custom Stage API External Item Descriptions - настроить на русский язык 2. Установи...4.0k downloadsupdated 3 y ago
- Birthright for all normal characters (OBSOLETE DUH)by Plaffy46™EDIT: YES, the mod is now obsolete after the released update. Finally, no one's left out. Implements Birthright effects for all Normal Characters. Effects due to include the tainted characters in the future annd/or change existing Birthright effects. -Isaac/???/Eve/Samson/Azazel/Lazarus/Lazarus R...4.0k downloadsupdated 5 y ago
- Fixed a Problem with the Restock Machineby Guilherme-right now there's a bug with the restock machine, basically when it explodes in any way it sometimes ends rerolling the items twice almost instantly, so it ends removing some items from the pool, which can be very annoying, I fix it by removing the restock machine in the moment that it explodes,...4.0k downloadsupdated 2 y ago
- AquaKnifeDR5by 76561198365265953Recolours Mom's Knife to look like one of the knives used in Aqua's bullet patterns in Deltarune Chapter 5. Also gives Isaac her small ribbon. Very, very high effort mod! (lie) Also maybe I fixed the blackbox thing!4.0k downloadsupdated 3 mo ago
- The Lighterby MouseThis mod adds a new item into the basement! ~THE LIGHTER~ - On damage Isaac transforms into a living bomb and has 2 seconds to decide where to explode! He also doesn't get damage from the explosion and from the enemies while he is exploding! He deals normal bomb damage (60 DMG) to everything in h...4.0k downloadsupdated 10 y ago
- Amazing Chest Aheadby Iris HeartThis mod aims to meddle a bit with them vanilla chests. Regular chests now have 5% chance to become wooden chests. Golden chests now have 5% chance to become old chests. Red chests now have 25% to drop a cracked key in addition to anything that was inside, and the Red Key is more likely to appear...4.0k downloadsupdated 3 y ago
- More Shell Game Itemsby kittenchillyDid you know the game has a Shell Game item pool but never uses it in favor of just spawning Skatole? This fixes that. Shell Game now spawns an item from the Shell Game pool instead of just Skatole! This is usually various poop items.4.0k downloadsupdated 4 y ago
- Triforce of Greedby certifiableGrimalkinA small mod of three items and one transformation. Was based on a friends idea to make something like Money = Power, but for other pickups. Adds: Power is Power - Damage up + Knockout tears + Damage up for every bomb one has. Wisdom is Power - Range up + Burning tears + Damage up for every key on...3.9k downloadsupdated 10 y ago
- Flying Contactsby ☢ Nato Potato ☢Flying Contacts makes your flies shielded like lost contact shots, potentially protecting you from enemy shots. This includes orbital flies like best bud, forever alone and distant admiration. It spawns 5 blue flies when you pick it up and makes sure you have at least 5 flies when entering a new...3.9k downloadsupdated 5 y ago
- Yankee with no BRIMstoneby MiggliHello! This Mod replaces the Brimstone graphics with Yankee with no BRIM(stone)! It adds a Sound effect and makes Isaac wear the cool hat! The SFX work again now thanks to !3.9k downloadsupdated 5 y ago
- ONESHOTby 76561198880252580This mod features 2 new characters, Niko and The World Machine both of them have exclusive to them active and passive items Alongside with that, this mod adds 10 new oneshot themed items (hopefully) more characters & items soon! We also made a custom menu! It features a custom intro, custom ui fo...3.9k downloadsupdated 3 mo ago
- Wooden Cross For Tainted The Lost [Smelter]by 76561199045465995A simple mod that allows Tainted The Lost to start with the Wooden Cross trinket but now in your collectibles list.3.9k downloadsupdated 2 mo ago
- Little friendsby VladirienThis mod adds 3 familiars into the game! Red Puppet : Flies around the room and sometimes fires tears when the player does in a circle, mimicking its effects - Synergies : * Ipecac * Brimstone * Technology * Tech X * Mom's knife * Dr Fetus * ... and others - Also has little costumes! - Found in t...3.9k downloadsupdated 9 y ago
- Grave of Gemsby xceptionalbroHello, hello! This mod is based in Steven Universe. Right now it don't have almost anything, but my TODO list is big, and keeps growing. Features: -Blue Diamond: + speed -Yellow Diamond : + damage -Pink Diamond: -nothing for now- -Rose Quartz: + damage + range + speed + speed shot -Pearl: + range...3.9k downloadsupdated 10 y ago
- AwfulTweaks [RGON]by Mr. HeadcrabThis mod requires Be sure to follow the full install instructions on repentogon.com Are you sick of the standard, well-thought-out challenge mods out there? Have you found yourself wanting a mod made primarily for the enjoyment of anyone watching you play? This might be the mod for you! This mod...3.9k downloadsupdated 4 mo ago
- Yippee replaces Cube Baby !by 76561199316727245This mod replaces Cube Baby's sprite with a cute lil fella ! Created by ReinsfZ :33.9k downloadsupdated 16 mo ago
- MORE detailed - The Stairwayby 76561199175201857Don't you think that the sprite of The Stairway is very simple compared to the others, besides containing a lot of black lines? This mod tries to fix that by modifying the sprite of The Stairway. Don't forget to leave your opinion in the comments and suggestions for other modifications, I will be...3.9k downloadsupdated 4 y ago
- [REP+] Always Map +by 76561199164471930Now compatible with mod config menu I was able to update this mod at the request of a comment to make it compatible with the Mod config menu. You can now decide which map effects are applied and customize them from the Mod config menu. Now the map, compass and blue map will not appear if an effec...3.9k downloadsupdated 2 y ago
- [Colored]Zodiac Items Into Constellations Respriteby 76561198452145624This is the colored version of Zodiac Items into Constellations resprite. More colors=BETTER. Enjoy! in case you want to check out the original version:3.9k downloadsupdated 10 mo ago
- Start Item Settingsby minishrek4This mod is based on the "Start Item Options" mod. it adds some settings to change what items spawn, and how many. options include how many items spawn. 0-28 how many items you can take. items that will always spawn. what item pools items are spawning from. min/max quality + more this is a WIP an...3.9k downloadsupdated 13 mo ago
- familiar overhaulby 76561198876704734I RELEASED A COOP BABY OVERHAUL MOD TO COMPLETE ALL THE CONJOINED FAMILIARS!!! GO DOWNLOAD IT!!! IT HAS 500 RESPRITES IN IT!! resprites like 90% of the familiars in the game, from brother bobby style conjoined familiars through sacks to all the bums. epic win sprites for boiled baby and juicy sac...3.9k downloadsupdated 7 mo ago
- Mysterious heritage2(额外的道具2)by 想你了牢大额外增加15种被动道具 以下是道具介绍,英文部分为google翻译(The following is the introduction of the props, the English part for the google translation): 1.紫焰:眼泪附加 中毒、燃烧 效果 1. Purple flame: additional tears poisoning, burning effect ---------------------------------- 2.护符:血量上限+2,幸运+10 2. Talisman: blood cap +2, lucky +10...3.9k downloadsupdated 9 y ago
- Blue Archive Reskinsby 76561199102200098Blue Archive (BA) Resprites for Bethany, Magdalene, and Jacob & Esau! This is a rework of my older mods, I redid the graphics and added a little more to them! I plan on adding more students and other item resprites in the future so please look forward! Current students included-- Koharu , Momoi &...3.9k downloadsupdated 2 y ago
- Exodus - Fast Travel!by NeopolisInvincibility and maximum speed! But only for rooms you've already cleared.3.9k downloadsupdated 10 y ago
- Tweaked My Reflection spriteby ViscerATweaked sprite for My Reflection. Now it actually resembles a cracked mirror! Well, at least I hope it does. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading e...3.9k downloadsupdated 6 y ago
- Light's Items 2by LightFrogLight's Items: Pack 2 Light's Items Pack 2 adds five new and unique items to The Binding Of Isaac: Afterbirth+. The Items: Torn Blanket 'Spooky' Passive Item Adds a chance for slain enemies to become ghosts, fighting for you for the current room. Found in boss rooms. Egg Timer 'Hard Boiled' Activ...3.9k downloadsupdated 9 y ago
- Giga Bombby NeoDementA simple active item that allows the player to drop a Giga Bomb when used. 4 room charge. I made this because after getting 100% in Repentance, I realised I'd never had a Giga Bomb in my inventory at any point. So I felt like a more common way to acquire them would be good. UPDATE 07/07/2021 Giga...3.9k downloadsupdated 5 y ago
- freaky dudes instead of effectsby 76561199016204414changes the giantbook popup of the following items to very freaky and sexy black men: - nencronomicon - monster manual - dead sea scrolls - sun card - book of belial - moms bra - anarchist cookbook - bible - death effect (skull) - Satanic bible - rainbow poop very funny.3.9k downloadsupdated 23 mo ago
- [REP] Plagues of Egypt Updatedby LaFunginatorUpdated Plagues of Egypt for Repentance! Original mod: Features: 10 new passive items Several items count towards vanilla transformations External Item Descriptions compatibility Changes: Plague of Frogs now gives 1 HP and now scales off of luck Plague of Lice adds to the spider baby transformati...3.9k downloadsupdated 2 y ago
- LSD Consumableby ArcticPlease leave a comment, I'd love to know what you think of my first mod! It's acid! Take it and freak out. Think your parents are trying to kill you! This mod adds a consumable with a 1/32 chance to replace cards and runes. Using it will make you see crazy sh*t, man. On top of that, it applies a...3.9k downloadsupdated 9 y ago
- Cricket's Pawby SalvageSpeed up + your feet feel stronger Passive Item Effect: 0.5 Speed up + immune to spikes and blood creep3.9k downloadsupdated 10 y ago
- Daemon's Heartby NiroDaemon's Heart 'Help from the underworld' When you pick up a black heart, a charmed imp is summoned to fight on your side! The imp stays with you until he dies. Spawns 2 black hearts on pick up. This item can be very good with things that give black heart drops, like Daemon's Tail for example. Fo...3.8k downloadsupdated 5 y ago
- Police Taserby MouseThis basement add a new mod into the item! ~POLICE TASER~ - Tears have now a possibility to transform into "Electro Tears" that have the ability to "taser" any enemy they come in contact with. Electrolyzed enemies can't move and periodically shoot out Tech Lasers that taser other enemies too. -Th...3.8k downloadsupdated 10 y ago
- Loki's cat earsby c:\re-sprite of loki's horns3.8k downloadsupdated 3 y ago
- Elegy of Emptinessby damagazThe Elegy of Emptiness is an active item that can be found in Treasure rooms. Using this item grants a statue which is based on one of Isaac's transformations. Each transformation has a different effect: Beelzebub gains a fly statue which creates blue flies, Leviathan gains a demon statue which s...3.8k downloadsupdated 8 y ago
- Tweaked Boomerang spriteby ViscerATweaked item sprite for Boomerang. Now it looks more like a boomerang, while keeping the original sprite's characteristics. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience,...3.8k downloadsupdated 6 y ago
- Start with Holy lightby BarjuhStart each run with Holy light Collection with all my Start with mods :3.8k downloadsupdated 4 y ago
- Friendly Explosivesby ☢ Nato Potato ☢The Friendly Explosives item gives you 5 bombs and makes you impervious to any explosions you create, that includes placed bombs, dr fetus, epic fetus, explosive diarrhea, fire mind, bob's brain, ipecac and more. It can be found in treasure rooms, gold chests and shops. This does not make you imm...3.8k downloadsupdated 2 y ago
1.3k items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

