Mods / Sound EffectsThe Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth sound effects mods
Everything filed under sound effects by its own author, ordered by how much it is used.
740 sound effects mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
740 sound effects mods
- FIRE IN THE HOLE!!!by 765611988029550047.0k downloadsupdated 25 d ago
- Isaac Reforged [Afterbirth+]by KaliThis mod aims to add and rebalance characters, synergies, and transformations, while remaining faithful to the vanilla experience. Supports External Item Descriptions! Supports Mod Config Menu! Supports Revelations! Supports Fiend Folio! & More! All changes are configurable with the Mod Config Me...7.0k downloadsupdated 6 y ago
- PvZ Soundtrack [Rep/Rep+]by Orda77Soundtrack from different Plants VS Zombies games ---------------------------------------------------------------------- !!!REQUIRES SOUNDTRACK MENU MOD!!! ---------------------------------------------------------------------- Track List: ----FLOORS---- Basement - Graze the roof {PvZ} Burning Bas...7.0k downloadsupdated 21 mo ago
- Mom's Bra into Omni Manby 76561198842992121Tired of seeing Mom's bra? Then try this mod! This mod changes Mom's bra into (Thicc) Omni Man. It also have sounds I dont know who already did this but.. Anyway, I made it. UPDATE: NOW IT CAN CHANGE MOM'S BRA ITEM NAME INTO OMNI MAN Thanks for this site! it DOESN'T affect other mods with XML files.7.0k downloadsupdated 3 y ago
- Miku Anouncer Modby 76561199376393245Changes all announcer dialogue into Hatsune Miku V4! Horse piills are reverbed, both because I'm lazy, and because i think it sounds nice. reverse cards are... well yeah that one was easy enough I did *some* testing, but let me know if there are any sounds where i messed the file names up (they'l...7.0k downloadsupdated 21 mo ago
- Miku Miku Blastby Apollo JusticeChanges the sound effect for Mega Blast to Miku Miku Beam Made entirely by psyleft7.0k downloadsupdated 20 mo ago
- JoJo (JJBA) Music Pack (REPENTANCE)by 76561199229829834This is a mod to change EVERY SONG POSSIBLE into a song from JoJo's Bizarre Adventure. Every song file, even jingles, were changed. Below is a list of the original Isaac songs, and what they were replaced by: MAIN: Title Screen - Hidden Thoughts Basement - Approach Cellar - Iggy walk Burning base...7.0k downloadsupdated 22 mo ago
- Quick Draw Mini-Gameby GuilhermeThis mod adds a new mini-game to isaac, the quick draw mini-game, based on the quick draw mini-game of kirby games. You will find sometimes a beggar holding a gun in the arcade, you need to have 5 coins to start the mini-game, interact with the beggar holding the gun when you have at least 5 coin...7.0k downloadsupdated 3 y ago
- Paper Mario Lucky Sound over Secret Roomby 76561199160403148Changes the secret room find sound to the lucky sound from Paper Mario; The Thousand-Year Door7.0k downloadsupdated 23 mo ago
- WhatsApp Whistle for Dingleby EthanChanges Dingle's whistle to the whatsapp notification6.9k downloadsupdated 3 y ago
- The Binding of Synth [Soundtrack Mod Edition]by Tar-BoneAs requested, here's The Binding of Synth now compatible with the Soundtrack Menu Mod and also compatible with the Jukebox Mod . Original Mod Here The Tracklist: ================= Floors ================= Basement: Jasper Byrne - Night Driver Cellar: Mega Drive - Video Stalker Burning Basement: C...6.9k downloadsupdated 4 y ago
- Scooby Doo Creepy Run replaces Chased By Deathby 76561199035670843This mod replaces Chased By Death with the theme song from Scooby Doo Creepy Run!!!! I saw a bunch of Tiktok comments asking for this and a bunch of videos editing it into the game so I decided to make it into an actual mod lmfao :P (THIS IS ONE OF TWO MODS I'VE MADE ABOUT SCOOBY DOO CREEPY RUN!!...6.9k downloadsupdated 5 mo ago
- Luigi's gold keyby 76561199102149926This Changes the Golden key sound effect with the "Get key" sound effect from Luigi's mansion 1 Enjoy!6.9k downloadsupdated 2 y ago
- Female moan Damage Sound!by 76561199422564608damage sound female moan.6.9k downloadsupdated 19 mo ago
- RIP Isaac Death Animation [Repentogon]by fly_6Requires REPENTOGON mod to work! Inspired by Undertale Death Animation and "R.I.P Spongebob" meme, this mod plays this particular death animation after player's demise You can also toggle on funny sounds on RIP animation (can be accessed from Debug Console/ImGui menu -> Fly Mods -> RIP Isaac Deat...6.9k downloadsupdated 12 mo ago
- Reverb Vine Boom sfx for Holy Mantleby 76561198986475370Replaces holy mantle sound to include vine boom with reverb. Thats it6.9k downloadsupdated 5 y ago
- The Grinding of Isaac: Meme Hellby XXL Pizzaytp sexer ruins isaac's life Replaces almost every sound effect and song in the game with meme trash and YTP humor. Features custom graphics occasionally. BEFORE PLAYING: Other mods that change player animations and sounds may cause compatibility issues. For the intended experience I reccommend d...6.8k downloadsupdated 4 y ago
- Purple Guy and Springtrap!by 76561198843280029-- Purple Guy Enters the Basement ! -- Adds the Purple Guy, William Afton, as a playable character in a unique slot! High damage, low shot speed. Purple tears! Unique item costumes. -- Springtrap Enters the Basement... -- The tainted variant of Purple Guy Fake Hearts Free Devil Deals Special Knif...6.8k downloadsupdated 10 mo ago
- Damogus - Damocles Reskinby banziFunny among us!6.8k downloadsupdated 4 y ago
- Sans over The Forgottenby 76561198995475535This mod resprites The Forgotten to be sans from Undertale. Funny skelton ehehehehe Commissioned by Poopfart Sprites and Thumbnail by Ferpe Code by Kattack and catinsurance NOTE: Repentogon is required for the custom mega mush costume and sound effects to be applied, but otherwise you can play wi...6.8k downloadsupdated 7 mo ago
- Kirby Super Star Soundtrackby moldy_train2Updated for Repentance! Make sure to have the Repentance version of Music Mod Callback before using. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Replaces all music and jingles possible with the...6.8k downloadsupdated 5 y ago
- MVmodby Full retardmv's comments when you play Todo: - add "ptit criket's head ?" when opening a chest - add "PAAAFF" when booss die - add "Oh le dime" when get a dime ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Missing sound : If you have any of theses, please send it to me at mvmodsound@gmail.com. - "brillant comme...6.7k downloadsupdated 10 y ago
- Headcrab's Grab Bagby Mr. HeadcrabIt's got all you need for a long journey downwards! This mod adds 5 unique items, 2 trinkets, and 1 consumable: Items: Vienna Sausages "Eat your botulism" Build up pressure as you take damage until you blow your top off, knocking back enemies and shooting out a heavy stream of blood tears for the...6.7k downloadsupdated 14 mo ago
- Metal Pipe Falling Shovelby SprSnpr_Peak falling metal pipe immersion. This mod changes the sound and sprite of the falling shovel that starts the Forgotten unlock. The shadow overlay is also changed from a shovel to a pipe. Forgive me for making this...6.7k downloadsupdated 3 y ago
- Plants vs. Zombies Soundtrackby 76561198345870300REQUIRES NATO POTATO'S SOUNDTRACK MENU MOD: May also require Knife Piece 2 Fixer, though this may vary from person to person: This mod changes the music of the game to various tracks from the Plants vs. Zombies franchise. Track List: === Floor Themes === Basement - Grasswalk (Plants vs. Zombies)...6.7k downloadsupdated 4 y ago
- Flight Reacts To Your Deathby 76561199074273315this is a mod that plays an audio clip of a flight reacts video when you die. it works on REP+ but im not sure about other ones if there's any bugs let me know6.7k downloadsupdated 5 mo ago
- Pain death Sound (WAAAAA/OAAAA)by GreyTenPain Death Sound (Waaa/Oaaaaa) I made this mod because the animation mod didn't have the sfx DOWNLOAD DEATH PAIN ANIMATION HERE:6.7k downloadsupdated 4 y ago
- Jevil over Chaosby 76561198329067281A mod that change the sprite of our favorite Item "Chaos" into an animated sprite of Jevil from Deltarune. It also change te item description and plays some of the character voicelines when picked up. This was my first mod so it may looks a little spaghetti coded inside hehe6.6k downloadsupdated 4 mo ago
- Jolly dad note dialog [REP/REP+]by 76561198419052590Changes the sounds of Isaac's parents arguing during ascent, to have a holly jolly Christmas Holiday Celebration. Also replaces ascent's background music.6.6k downloadsupdated 11 mo ago
- i ve played these games before over loading choirby KartoxI ve played these games before over loading choir6.6k downloadsupdated 22 mo ago
- Wind Waker Explosion and Soundby SpongePierreAn explosion in the style of The Legend of Zelda Wind Waker, but most specifically based on the ones in Four Swords Also replaces the sound effect with the one from the games Pixelated version here: Known Issues -Huge and Small explosions will look weird and I have no idea how to fix it -Duke of...6.6k downloadsupdated 5 y ago
- Secret Room - Minecraft Cave Soundby HillmerThis small mod changes the sound effect of opening a secret room to the sound of a minecraft cave. I was inspired by this mod, but I thought this sound effect was more suitable for secret rooms because they are literally caves. This mod is compatible (x to doubt) with any DLC or music mods (unles...6.6k downloadsupdated 4 y ago
- YAY! Item Pickup Soundby 76561199652670853Plays the YAY! sound Fluttershy (MLP:FiM) makes when picking up any item6.6k downloadsupdated 13 mo ago
- [REP] The Ghostfaceby 76561198384958304Our favorite killer has entered the basement. The Ghostface starts with: • Dark Arts (Pocket Active) • Infamy • Mom's Knife • Dark Matter • Get out of jail free card And the following attributes: • 1 bone heart, 2 black hearts and 3 broken hearts • Speed: 1.00 • Range: 6.50 (Tiles) • Tears: 2.73...6.5k downloadsupdated 5 y ago
- Mohammad Rajab Wali for Mom's Shadowby Moltarjoe biden wake up6.5k downloadsupdated 5 y ago
- Flash Heart Soundsby BullettPsychoChanges the Sound Effect of Soul and Eternal Hearts to the Flash Ones. Genuinely surprised noone did this already. This is my first mod and I had to use this as a base:6.5k downloadsupdated 5 y ago
- Isaac is F***ING P*SSED!by z0mbiesrockBasically this is an audio mod from Skyrim called "Swearing Mudcrabs". This mod replaces sound effects of getting hurt to joyful swears. I do not take credit for making the sounds.6.4k downloadsupdated 10 y ago
- 009 Isaac System - Beastscapeby OceanMan"hello guyz. today i will show you how to defeat the beast in the binding of isaac: repentance :p" Replaces The Beast's death scream with 009 Sound System - Dreamscape. Based on the Beasts' Paradise mod by AgentCucco. May not work with other mods that overwrite sound effects.6.4k downloadsupdated 5 y ago
- True Secret Final Ending Cutsceneby oilyspoilyGO F*** YOURSELF! Changes the Delirium ending to this video by LeatherIceCream: Thank you Leather for the video, and thank J.D for helping me with uploading the mod!6.4k downloadsupdated 4 y ago
- Godmode汉化模组by 76561199253021281⚠️该模组已过期，请在我的合集里下载新的EID汉化模组⚠️ 这是一个对Godmode Achieved模组的EID进行了汉化的模组 请确认你已安装了Godmode Achieved和EID 汉化作者：B站@青灼QWQ 感谢B站@长山小春0213 提供的汉化帮助6.4k downloadsupdated 2 y ago
- Siren Chicken Screamby 76561199467726628Siren Does the Chicken Screaming on the Tree it only changes the screams the singing keeps the same once again icon made by Malorde6.4k downloadsupdated 9 mo ago
- You Little Fücker - The Pillby ViscerAI made a shit of piece with my trash mod6.4k downloadsupdated 5 y ago
- Majora's Mask Soundtrackby moldy_train2Updated for Repentance! Make sure to have the Repentance version of Music Mod Callback before using. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Replaces all music and jingles possible with the...6.4k downloadsupdated 5 y ago
- flightreacts scream death soundby CelesteinikFlightreacts screams whenever you die :)6.3k downloadsupdated 5 y ago
- NecoArcby Toony_Xenon- Magdelane has been replace with Neco-Arc - Tainted Magdelane has been replace with Neco-Arc Chaos - Yum heart is now Pilk - co-op sprites are changed - in between level sprites are changed - character select sprites are also changed6.3k downloadsupdated 5 y ago
- plants vs zombies coins zoundby 76561199030125176(ENG) This mod will replace coins with coin sounds from Plant vs Zombies. 1 penny-just coin (pvz) 5 penny-coin with increased tone (+4 in audacity) 10 penny diamond (pvz) lucky penny- the sound of a gift (pvz) thanks Pop-cap for the sound and texture for this icon and thanks text studio for the t...6.3k downloadsupdated 21 mo ago
- INNER SANCTUM (Soundtrack Overhaul)by HengusMA passion project developed tirelessly over the span of a few months, INNER SANCTUM is an original interpretation of the game's score with a heavy emphasis on action and atmosphere befitting of the game's derelict, melancholic vibes. Every major track in the game is complete! The entire soundtrac...6.3k downloadsupdated 23 mo ago
- empanadasby 76561198360340738Cambia el efecto de sonido de aparición de la sala de satan por el tétrico meme de Dross. Si el mod te gustó, por favor dale pulgar arriba y comenta.6.2k downloadsupdated 5 y ago
740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.