Mods / Sound Effects

• NNEW Money pick up soundby 76561198384344742All Coin pickup sounds are replaced with Mr.Krabs money money money Lucky Penny sound is replaced with Spongebobs money money money (Does not work for Afterbirth+) from this video4.0k downloadsupdated 6 y ago
• FFlightReacts Larynxby GaussTheWizardReplaces the high-charge Larynx sounds with an edited sample of FlightReacts' famous scream. sh*tposting is inevitable4.0k downloadsupdated 5 y ago
• SSNES Mario Soundtrackby Strangle McDangleMario Soundtrack for Repentance Replaces all music and jingles possible with the Soundtrack Menu mod by ☢ Nato Potato ☢. Uses various tracks from: Super Mario All-Stars (Super Mario Bros) Super Mario World Super Mario RPG Mario Paint Yoshi's Island Track List: -------------- Floor Music ---------...4.0k downloadsupdated 5 y ago
• EEngineer Pickup Sounds++by DaLuigireplaces pickup sound of Hearts, Coins, Bombs, Keys, Batteries, Pills Good/Bad (including Horse Pills) and Item Pedestal pickup with TF2 Engineer voice lines Take a look in the discussion thread if you have any suggestions/feedback! also Front Page!Yippekeeyah-heeyapeeah-kayoh!4.0k downloadsupdated 4 y ago
• YYankee with no BRIMstoneby MiggliHello! This Mod replaces the Brimstone graphics with Yankee with no BRIM(stone)! It adds a Sound effect and makes Isaac wear the cool hat! The SFX work again now thanks to !3.9k downloadsupdated 5 y ago
• Kkurwa mamoby 76561198989606598replaces mother's shadow yell thing with KURWAAAA yeah thats it3.9k downloadsupdated 21 mo ago
• TThe (Possible) Nostalgia Music Packby seeaanHEY! This mod has a Soundtrack Menu compatible version now! Go get it (If you want to...): Tired of the same old BORING music? No? TOO BAD! Install this mod right now and enjoy some classics from an ANCIENT ERA. These soundtracks will (probably) knock your socks off and (possibly) bring you back...3.9k downloadsupdated 5 y ago
• MMAODIE over WIDOW (no music update)by JunkBroThis time I changed the cute boss "Widow" so that now he looks like a spider cat named MAODIE, the cat from the video on the bilibili platform, maybe you saw him in the funny scab videos posted on YouTube The mod changed the Widow sprite (also champion versions) and the transformation of the Dily...3.9k downloadsupdated 8 mo ago
• TThwomp High Preistessby 76561199590469868Changes mom and satan stomps and sfx into super mario 64 twomps3.9k downloadsupdated 2 y ago
• CChained Togetherby KerkelChained Together Are you tired of playing co-op mode with your difficult friends who keep stealing your items, don't follow you in large rooms, or are otherwise uncooperative? Look no further than the Chained Together mod to make your co-op experience better, or even worse by combining a tedious...3.9k downloadsupdated 2 y ago
• FFamily Guy Transitionsby 76561198866871514Changes the transition floor music to a family guy transition. This is the fixed version. Boy this was worse than the time I fell in that basement3.9k downloadsupdated 4 y ago
• Bburmaldaitemspecialistby 76561198842815654That mod is copy of "Specialist Dance for Good Items" mod, Original: that mod adds 32 different mellstroy remix music's Also inspired from "vottakoihamamforgooditems" mod. my boosty: Mostly published for my friend.3.9k downloadsupdated 3 mo ago
• AAwfulTweaks [RGON]by Mr. HeadcrabThis mod requires Be sure to follow the full install instructions on repentogon.com Are you sick of the standard, well-thought-out challenge mods out there? Have you found yourself wanting a mod made primarily for the enjoyment of anyone watching you play? This might be the mod for you! This mod...3.9k downloadsupdated 4 mo ago
• TTwilight Princess Soundtrackby MorganiteSoundtrack from The Legend of Zelda: Twilight Princess. Please let me know of any issues or suggestions in the discussion thread! Track List: -------------- Floor Music -------------- Basement = Hyrule Field Cellar = Hidden Skill Training Burning Basement = Death Mountain Caves = Faron Woods Cata...3.9k downloadsupdated 5 y ago
• MMeat Wormby CarterG4Turns the Round Worm enemy into Meat Worm - also works with champion variants Includes meat sounds for the worm spit sounds, which may make other enemies sound like meat3.9k downloadsupdated 5 y ago
• MMeme Death Soundsby LycaReplaces Isaac's death sounds with flightreacts, taco bell, and the vine boom.3.9k downloadsupdated 5 y ago
• JJerma Teacher Noise for Secret Roomsby 76561198368387389Turns the secret room jingle into the Jerma teacher noise.3.9k downloadsupdated 5 y ago
• JJojo Tarot Cardsby TelemarcusI replaced all of the audio files for the announcer when he says the name of the Tarot cards to Stand users from Jojo's Bizarre Adventure saying them. I had to use the English version of The Sun since the name of the stand was never officially said in the episode it premiered in.3.9k downloadsupdated 7 y ago
• SShop's music - Temmie Villageby 76561198880944602Changes the music in the store to the theme of Temmie Village from Undertale WITH THE MOD Antibirth music++ MUSIC WILL NOT WORK But it can be fixed. Go to the folder with the game, follow the path ...\mods\antibirth music++\resources\music And there we delete 2 files store loop.ogg and store loop...3.9k downloadsupdated 2 y ago
• SSad Pickups SFXby SoundbinNow melodic pickups sounds are sad just like our good old friend Isaac :(3.8k downloadsupdated 2 y ago
• AAlexelcapo Modby TremensMod de Alexelcapo. Este mod contiene: Nuevo personaje: Alexelcapo 1 Item activo 2 Items pasivos 1 Familiar(Halfonso) 1 Habilidad especial del familiar Sonidos de muerte, daño y uso de item activo. Y muchos de sus memes. Descripción de los items: -Falta daño: Al agarrarlo reduce el daño del person...3.8k downloadsupdated 9 y ago
• Bbua wa wa sound effect upon entering item roomby 76561199498748222!the mod works fine, it's just really quiet for some reason. If no sound effect/ another sound effect plays you have a mod that makes this one not work! this mod will play the bua wa wa wa (some might know it as the rizz sound effect or something like that) idk why this specifically but oh well3.8k downloadsupdated 12 mo ago
• BBombastic_Flyby 76561199102149926This replaces the Sprited for BBF with the great Mista Boombastic Now with lil delirium reskin as well as an item pickup sfx The pickup name should be changed thanks to I Hope you enjoy!!3.8k downloadsupdated 2 y ago
• DDorime Angel Room Music Replacerby HillmerDon't worry, it doesn't change the appearance of the angel statue! (unless you want it, you can turn it on) I put it there just for the memes, bois. ඞ This mod replaces the music of the angel room with the "Era - Ameno (remix)" meme. The Mouse Statue is initially disabled because I thought most p...3.8k downloadsupdated 4 y ago
• SSonic Adventure Soundtrackby Lady LuckyBack with another track! This time, it's sonic adventure! Surprised it hasn't been on the workshop sooner. This was one of my other major projects aside from my Tales of soundtrack. Keep an eye out though! I will be trying my best to do Shin Megami Tensei Nocture, and Sonic Adventure 2! This pack...3.8k downloadsupdated 4 y ago
• MMemes for HP up food itemsby 76561198842992121Have you been tired with food items? especially health up items? Now this mod makes food items more interesting! This mod adds unique sound effects when picking up food related health up items. Including: -Breakfast -Lunch -Dinner -Dessert -Rotten Meat -A Snack -Midnight Snack -Supper Have fun wi...3.8k downloadsupdated 11 mo ago
• ""Dog covering nose meme" SFXby 76561198324384778Changes the negative sound effect for consuming bad pills, losing on a slot machine or pressing buttons for the semi-popular "dog covering nose meme" audio. I hope you'll like it!3.8k downloadsupdated 4 y ago
• OOOF modby MoleyWhenever you get hit, you hear the Roblox death sound instead. Created by ya boi GonadsPC3.8k downloadsupdated 10 y ago
• PPeppino Larynxby Apollo JusticeFor those like me that have been infatuated with Pizza Tower, I decided to make a mod that changes the Larynx sound effects to the funny Italian man's screams3.8k downloadsupdated 4 y ago
• HHandsome Jermaby IndefixChanges Mom Shadow to Handsome Jerma run3.8k downloadsupdated 3 y ago
• HHector from OMORIby 76561198346397289This mod add beloved pet rock of KEL from OMORI. Unfortunately, you can't return Hector to Kel, so you can become his new friend! Change sprite for "The Small Rock" and "Rock Bottom" Сhange sprite for character with these items. Сhange their name and description. Add sound effect when picking up.3.8k downloadsupdated 3 y ago
• 110 cards packby 7656119880340664810 new cards have appeared in the basement! ·This mod adds 10 new cards with new effects to the game! Cards list: - God card *Effects: It has a 95% chance of giving you a coin and a 5% chance of giving you godhead *Spawn chance: 0.5% - Mirror card *Effects: Changes all your items (like D4) *Spawn...3.8k downloadsupdated 7 y ago
• AAntibirth for AB+ (and Repentance)by im_temDo not install this if you want to play Antibirth, go to antibirth dot com instead Antibirth was made by P.E.N.I.S team, not me or even better, get yourself Repentance instead of running this, dammit! ----- Antiborne is now real, even for Afterbirth+ (now also for Repentance!) Let's be honest, yo...3.8k downloadsupdated 4 y ago
• PPure Nail Spirit Swordby ZyckroThe ultimate weapon of Hallownest has appeared in the basement! This is a resprite for the Spirit Sword item, changing its appearance to match the titular weapon from Hollow Knight. Enjoy!3.7k downloadsupdated 3 y ago
• VVVVVVV's Super Gravitron [Rep/Rep+/AB+]by JSGExpected an Isaac mod?....Late-March Fools!, it's VVVVVV's super gravitron but in Isaac. Ya, basically, just that, I remade an easier version of the VVVVVV's Super Gravitron as an AB+ mod challenge. How can I play it? Access the challenges menu and press tab, then look for "Super Gravitron". Make...3.7k downloadsupdated 4 y ago
• SSIUUUUUUUU for Larynxby Hideo KojimaSIUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU Requested by: u/hxllxqxxn3.7k downloadsupdated 4 y ago
• TThe Binding Of Linkin Park (Music Mod)by The Black ParadeThis mod changes all music in Binding of Isaac to instrumental Linkin Park songs (I do NOT own any rights to any songs in this mod, all rights goes to the original creator, Linkin Park.) (disclaimer: Some music may be edited) The list of songs in game: Basement - Hit The Floor Cellar - Figure.09...3.7k downloadsupdated 8 y ago
• TTyler1 Death Soundby Thiccy BobbyReplaces default death sound with the fading out Tyler1 scream.3.7k downloadsupdated 5 y ago
• DDiamond sword over spirit swordby 76561198372192441Mod changes all spirtes for spirit sword to diamond sword from minecraft (also some sound effects)!3.7k downloadsupdated 4 y ago
• PPizza Beastby MADAOIt's PIZZA BEEEEEEEEEEEEEEEEEEEEEEAST!!!3.7k downloadsupdated 3 y ago
• SSilent Hill 2/3 Soundtrackby 76561198349205923Music from Silent hill 2/3. Track List: -------------- Floor Music -------------- Basement = A World Of Madness Cellar = A World Of Madness Burning Basement = A World Of Madness Caves = Null Moon Catacombs = Null Moon Flooded Caves = Null Moon Depths = Heaven's Night Necropolis = Heaven's Night D...3.7k downloadsupdated 5 y ago
• FFightable Mother's Shadowby catinsuranceRequires REPENTOGON For more information, visit FIGHTABLE MOTHER'S SHADOW Ever thought the Mines escape sequence for Knife Piece 2 was too long or tedious? Or maybe, you just wanted to shake up the experience after going alt path every time? This mod turns Mother's Shadow into a boss fight. Defea...3.7k downloadsupdated 12 d ago
• SSUPER Binding Of Isaac (Soundtrack Menu Version)by Chao TsundoClassic SNES Tunes! (Note: This is the version of the mod designed to work with the Soundtrack Menu Mod, as requested by someone in the comments of the original. I'm leaving the original version because this mod doesn't allow me to change music like the title screen and some of the other jingles....3.7k downloadsupdated 5 y ago
• EExtinguisher of Soulsby SprSnpr_Extinguish Their Souls!!! This is a mod that changes the sprites and sound effects of the Urn of Souls to resemble a fire extinguisher. That's all. Everything related to the Urn of Souls has been updated- except for one thing. Judas and Dark Judas' birthright gives them a unique sprite and effect...3.7k downloadsupdated 3 y ago
• SSteamed Hams Ascentby British BeetlemaniaThis replaces the dialog for the ascent with Steamed Hams, because sure LOL3.7k downloadsupdated 4 y ago
• BBFG Division for Tainted Samsonby ab5urdThis mod adds DOOM soundtrack for Tainted Samson's Berserk!3.7k downloadsupdated 5 y ago
• TThe Binding of Pokimon Mystery Dungeon [Afterbith + Edition]by NarxThe Binding Of Pokimon Mystery Dungeon is a mod that turns Isaac's basement into pokemon mystery dungeon world, includes PMD levels, bosses soundtrack sound effects and much more... DOWNLOAD FULL VERSION HERE: mega. nz/file/yhEADZpa#X9R9MN2_tNITsbixkOxlmknccSU1cBjsD5GEUmaVbwI FEATURES: -Playable...3.6k downloadsupdated 6 y ago
• AAgony Flies - The Grinding of Isaacby XXL PizzaAll flies now scream in agony until they die. From The Grinding of Isaac. Full mod here: Thumbnail sprite:3.6k downloadsupdated 5 y ago

740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.