The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth sound effects mods
Everything filed under sound effects by its own author, ordered by how much it is used.
740 sound effects mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
740 sound effects mods
- Eric Cartman Laugh On Deathby 76561198848346428Eric Cartman laugh on death4.9k downloadsupdated 3 y ago
- Ethiopian jazz in shopby Dr FimozA classic song Yéggellé Tezeta from Mulatu Astake plays in the shop. Very ethiopian, very jazzy, very buissnessy. compatible with soundtrack menu mod4.9k downloadsupdated 17 mo ago
- Mega Man Teleportby CheadleWARNING: This mod changes the character sprites, meaning any mods that also change them will conflict! Yes I'm back with a quick mod This mod changes every character and character color, meaning items or transformations that change your color carry over with the teleport sprite (how cute) I've al...4.9k downloadsupdated 4 y ago
- The Memeing of Isaac (ABANDONED)by Obama MonarchyReplaces most sounds and music with dank memes, including: Big Smoke Replaced the coughing and dry heaving noises with Ethan's coughs from H3h3productions Pawn Stars A bunch of siIvagunner music and MUCH more! Some placeholder music is there until I find some more dank memes to fill Isaac with. S...4.9k downloadsupdated 10 y ago
- Minecraft cave sounds for item roomsby PixelPlzlow quality and unfunny only replaces the sound files so it works with music mods :)4.9k downloadsupdated 5 y ago
- Touhou Tunes for Soundtrack Menuby teelThis is a port of my older Touhou music mod. Use both together for the complete Touhou experience! This mod also supports the Jukebox for displaying track names. ===Tracklist=== Basement - EoSD A Soul As Red As Ground Cherry Cellar - DDC Mist Lake Burning Basement - IN Illusionary Night ~ Ghostly...4.9k downloadsupdated 14 mo ago
- Gangsta's Paradise Oh Choirby 76561198439894059Don't thank me4.9k downloadsupdated 4 y ago
- Kirby 64 Soundtrackby moldy_train2Replaces all music and jingles possible with the Soundtrack Menu mod by ☢ Nato Potato ☢. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Track List: -------------- Floor Music -------------- Basemen...4.9k downloadsupdated 5 y ago
- Cult Of The Lamb soundtrackby Californie_Paradis_des_SansAbrisCult of the Lamb soundtrack for TBOI: Repentance Requires Repentance, Soundtrack menu ( Jukebox Rep ( ) and REP Callback ( to work. <!-- Floors --> Basement : Start a Cult Cellar : Sacrifice Burning Basement : Saviour Downpour : Darkwood Downpour (reversed) : Ratoo Dross : The Night Dross (revers...4.8k downloadsupdated 4 y ago
- Mondongo Babyby TheCamrewNo hay mucho que explicar4.8k downloadsupdated 14 mo ago
- Mom's Foot Reminderby JujuI can't count how many runs I threw away by running into the boss room without thinking on floor 6. This mod fixed that. It will remind you that the upcoming boss fight is Mom's Foot. Whenever you stand next to Mom's Foot boss room, and your current room is cleared, you will hear mom screaming fr...4.8k downloadsupdated 3 y ago
- Hank Lazarusby 76561199086539150This mod changes Lazarus and Tainted Lazarus into diffrent forms of Hank from madness combat All credit To my friend Jebus on the sprites whilst I did the portraits.4.8k downloadsupdated 5 y ago
- Horsier Horse Pills™by SprSnpr_Say 'neigh' to boring horse pills! I've spruced up the horse pill sound effect with some equine nonsense.4.8k downloadsupdated 5 y ago
- I.S.A.A.Cby BarneyThe Intuitive System for Assisting in the Annihilation of Creatures! This mod adds a new active item to the treasure room pool that freezes enemies in their place, allowing you to select one to fire a volley of 5 of your tears. IF YOU'RE GETTING A BLACK SCREEN WHEN PLAYING THE GAME, TRY USING THE...4.8k downloadsupdated 4 y ago
- Reveal the Ultra Secret Room more!by kittenchillyThis mod adds new functionality to every item that reveals both the Secret and Super Secret Room by having them reveal the Ultra Secret Room as well! This effects Blue Map, The Mind, Ansuz, and Book of Secrets. Also, Dog Tooth now plays a sound of a dog whining if you are in a room that can lead...4.8k downloadsupdated 14 mo ago
- Dingle Is Flo Ridaby CrystaoChanges Dingle's whistle (as well as plum's flute) to Flo Rida's whistle4.8k downloadsupdated 3 y ago
- Less Annoyng Montezumaby AutosarThe original sounds for that item is very, very... annoying. And that's exactly why i made this. Replaces montezuma's sounds with standart brimstone sounds.4.8k downloadsupdated 4 y ago
- Olga [RGON]by 76561198799401126From the creator of Phonk Troll Bombs , I present to you, Olga! Olga is a small, mostly cosmetic mod for Repentance. It aims to add a brand new familiar that can be interacted with. I basically brought my dog in game for everyone to enjoy. What to expect: Your very own Olga, complete with her own...4.7k downloadsupdated 15 mo ago
- oh my godby NeuFlaasvine man announces your discoverance of an item4.7k downloadsupdated 5 y ago
- Banjo-Kazooie Soundtrackby moldy_train2Updated for Repentance! Make sure to have the Repentance version of Music Mod Callback before using. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Replaces all music and jingles possible with the...4.7k downloadsupdated 5 y ago
- Anvil dropby ThingKingTMSOUND PROBABLY DOESENT FUNCTION AS IT SHOULD. Daddy longlegs (item) is replaced by an anvil ( this also changes the legs of the daddy long legs boss ) Added sound effect when the item deals damage.4.7k downloadsupdated 4 y ago
- Isaac's ultimatumby 76561198802955004Merry Christmas and Happy New Year. This mod changes intro to animation stylized as PilotRedSun's Grinch's ultimatum.4.7k downloadsupdated 3 y ago
- !gangnamAzazelby 76561199592738163It began from nowhere -- perhaps from Azazel's sneeze perhaps from someone's silly idea the pestilence named Gangnam Style is quickly spreading around the basement! Can you be the hero to stop this pandemic? AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA this is a sfx mod at the beginning, and for Azaze...4.7k downloadsupdated 10 mo ago
- Coins are Rotating Cheeseby 🎮-_MAX_-🎮This mod just replaces all coins with rotating cheese. It's time to cheese!4.7k downloadsupdated 16 mo ago
- One Piece Soundtrackby 76561199142599123One Piece Soundtrack Mod is Finally Here!!!! Music so you never feel like quiting! (Can't be the pirate king by quitting) Pretty much an uplifting music mod. Downpour/Dross/Ashpit songs are sad. Home song kinda makes feel at home. And, ascent song is just perfect, it lets hear the echoes and make...4.7k downloadsupdated 17 d ago
- Alan Says Good or Bad Itemsby 76561198423227376When this mod is active a voice line of Alan from Smiling Friends will play once an item is picked up. If the item is of quality 3 or higher Alan will say "Thank God Finally" from S2E3 If the item is of quality 2 or lower Alan will say "What the f*ck?" If the item is blacklisted the normal game s...4.7k downloadsupdated 10 mo ago
- Ice Princessby 76561198353126873This mod REQUIRES StageAPI and Revelations to function. -Description- Within the cold walls of the Glacier, A new foe rises to take center stage. The Ice Princess has set herself a goal to become the greatest figure skater In the Glacier. and just so happens you've shown up right before her pract...4.6k downloadsupdated 3 y ago
- (OUTDATED DO NOT USE) Another Graphical Overhaulby RareFor years, there have been things that have bothered me about Isaac. It's mostly small stuff, but it's there, and I've finally decided to go out and fix it. Here is the result of my work, as well as the work of many others (all used with permission), combined into one convient mod. -Screenshots a...4.6k downloadsupdated 9 y ago
- pokemon bw soundtrackby PékipuPokemon Black ans White Soundtrack mod for The binding of Isaac Repentance ! Works with the soundtrack menu mod by ☢ Nato Potato ☢. Track list : FLOOR MUSIC : Basement : Kanoko Town Cellar : Pokemon Laboratory Burning Basement : Professor Araragi Caves : Let's Go Together! Catacombs : Hodomoe Cit...4.6k downloadsupdated 5 y ago
- isaac's lobotomy (FIRE IN THE HOLE)by 76561199121244854Isaac gets a lobotomy! yippie what it does: - turns brimstone into extreme demon - makes you featured if you have 2 or more brimstones (aka gives yellow glow) - turns tmtrainer into normal face - changes brimstone sfx by overlaying "fire in the hole" - plays "fire in the hole" on pickup - changes...4.6k downloadsupdated 3 y ago
- Zelda Musicby rocketThis is a mod Ive been working on which replaces all the music in the game with themes from many of The Legend of Zelda games! I thought it would make sence to make a mod like this considering part of Isaac is based on the original Lengend of Zelda game!4.6k downloadsupdated 9 y ago
- Sonic Mania Soundtrackby Lady Lucky***SOUNDTRACK COMPATIBLE*** Hello, hello! Back with another sonic track, at this point I might as well be referred to as that one person who really likes to port Sonic stuff into the workshop. But anyhow, I'm doing Sonic Mania! Due to the release of Sonic Origins coming out soon, I wanted to do s...4.6k downloadsupdated 4 y ago
- Tung Tung Devil replaces Satanby 76561199311872895dont worry hes with tung now TUNG TUNG DEVIL REPLACES SATAN only replaces statue, not boss sorry not sorry maybe if this gets on front page of workshop ill consider it winkwinkwinkwinkwink tung tung god here:4.6k downloadsupdated 7 mo ago
- Dave (+7 Unlocks) [RGON]by 76561199068958594Meet Dave - The Clone Consumer! Dave is a soul‑heart only character and he spawns 0-2 of his clones upon clearing a room, with a cap of 17. Have your horde fights alongside you, or consume them for a room‑lasting boost in power! Credits chuz: Creator of Dave, mod concept, and sprites natalia_pngi...4.5k downloadsupdated 4 mo ago
- A Horrible Creature (Pearto Beast)by 76561199231318073changes the beast into a HORRIBLE CREATURE it makes sounds aswell............ tested on rep+ listen to Science by MIMI or Machine Love by Jamie Paige4.5k downloadsupdated 17 mo ago
- Neco Arc Jumpscareby GodWladiDoridoridori :3 This mod adds a rare and unpredictable jumpscare to The Binding of Isaac. Occasionally, a random Neco Arc image will appear on the screen along with a distinct sound effect, startling the player and freezing all enemies temporarily until the player starts shoothing again. By defau...4.5k downloadsupdated 23 mo ago
- Undertale Jingles! [MJ!R]by SoundbinMore Jingles! REPENTOGON is required Adds Undertale jingles!4.5k downloadsupdated 3 mo ago
- "aw hell nah bruh" death jingleby 76561198367903733makes it so that when you die, the jingle is a bunch of guys who are disappointed in you, no matter WHERE you were in your run4.5k downloadsupdated 4 y ago
- Lego Yoda Death Screamby JustMiep :3Just a simple Mod i threw together which replaces the death sound of the player character with the infamous Lego Yoda death scream!4.5k downloadsupdated 5 y ago
- Danganronpa Soundtrackby Mr. VisionIs there no hope left in the world? Is Isaac doomed to suffer through despair? With this mod, you can guarantee it! Make sure to have the Repentance version of Music Mod Callback before using. Replaces (most) music with the Soundtrack Menu mod by ☢ Nato Potato ☢. Most of the music in this mod is...4.5k downloadsupdated 5 y ago
- TTYD Lucky SFX for Lucky Penniesby 76561198968629062LUCKY :D The Lucky sound effect from Paper Mario TTYD is played when you pick up a lucky penny!4.5k downloadsupdated 5 y ago
- Devil may cry 3 Soundtrack (Soundtrack Menu)by 76561198349205923requires soundtrack menu mod Music from Devil may cry 3. Track List: -------------- Floor Music -------------- (the alternate path uses the same music of their normal stage counterparts) Stage 1-2(Basement,cellar,etc) = Taste the blood Stage 3-4(caves,catacomb,etc) = Divine hate Stage 5-6(Depths,...4.5k downloadsupdated 5 y ago
- TikTok Narrator Voice for Itemsby 76561198784125343this mod adds 731 voice lines for items and 189 for trinkets. modded items/trinkets ofc dont have voice lines4.5k downloadsupdated 3 mo ago
- William Afton (Springtrap) Is Mom's Shadowby HengusM"I ALWAYS COME BACK." -William "Springtrap" Afton (Deceased) Run from the EVIL child murderizer, William Afton. Or his ghost. Or Springtrap. Or his digital remains. Or whatever the hell he is. Looking for more children to kill, 'Ol Willie has set his sights on a new crying child to bulldoze. Litt...4.5k downloadsupdated 19 mo ago
- turn isaac into dave bluntsby everyone4.4k downloadsupdated 22 mo ago
- Evol the Eeveeby BennyNew Character: Evol! Evol is a silly little Eevee that makes his way through the basement with Shadow Ball! *Note: This mod does not use any code related to the Eevee Mod, so methods such as evolving into or unlocking eeveelutions will not work. Character Features Evol uses the same sprites as th...4.4k downloadsupdated 7 y ago
- Kirby Music Mod (REP)by knuxchux(Only works with Repentance) REQUIRES SOUNDTRACK MENU Jukebox Recommended! This mod replaces all the music with Kirby music as an experiment to hear Isaac with a more energetic soundtrack. Also because I love kirby With this new update that brings Soundtrack Menu + Jukebox support, please notify...4.4k downloadsupdated 5 y ago
- Explosive Diarrhea Shittsing Editionby ChickenfayceI changed the Explosive Diarrhea pill sound and horse pill version to a voice over a user did of a comic I love dearly Original comic: Voice dub Audio:4.4k downloadsupdated 5 y ago
740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

