Mods / Sound Effects

• IInisaacable introby RanburuA little mod that changes intro clip to Inisaacable one. Enjoy :) Video made by myself. And full video link: Also you need to turn up music volume in the settings so you can hear audio.62.7k downloadsupdated 19 mo ago
• DDio Brando (JoJo no Kimyou na Bouken) (Not Repentance-Compatible)by Badass PhysicistDio Brando, the antagonist of Phantom Blood and JoJo's adoptive brother, known for rejecting his humanity to become a vampire and rule THE WORLD. Dio Brando starts with 2 bombs, 1 key, 3 black hearts and 1 red heart and a pack of vampiric powers. The mod includes Phantom Blood's ending, new sound...62.3k downloadsupdated 8 y ago
• RRest with a pretty lady (reupload)by 76561199521813785adds a pretty dark lady to isaacs bed she kisses you good night has secrets you dont wanna hear yet compatible with mod config menu mod made by Winter R3d steam profile: known issues: breaks spawn indicators60.2k downloadsupdated 12 mo ago
• EExcelsiorby RENRENA reimagining of The Binding of Isaac's OST. Made with love and something else that I cant remember. Just wanted to say THANK you for the massive support on this remake, blown away by the massive amounts of people. Please enjoy! OST LINK: YOUTUBE LINK: +=+=+ Q&A Q: Will you finish this? A: it is...59.9k downloadsupdated 2 y ago
• SSilasby MaddogsBring the world of mad science into The Binding Of Isaac with Silas! You can use four different potions to storm through the levels: Green potions create creep at a long range Red potions are thrown far, but explode on contact Yellow potions can apply any status effect at medium distance Blue pot...59.0k downloadsupdated 10 y ago
• MMetal Slug Explosionsby CheadleChanges the main explosion sprite and sound to replicate the classic Metal Slug explosion! No other sprites or sounds have been changed. ------------------------------------------------------------------------ From the creator of the LEGO Studs mod Shoutouts to Tear Of Grace and Grayfruit57.3k downloadsupdated 5 y ago
• [[AB+] DDLC Isaac Modby CrashpunkOUTDATED! DOES NOT WORK WITH REPENTANCE! DOWNLOAD THE NEW VERSION! >>>Doki Doki Repentance<<< Featuring new items, Tainted Dokis, Birthrights, many bug fixes and reworks! --------------------------------------------------------------------------------------- Doki Doki Literature Club! Isaac Mod (...56.2k downloadsupdated 5 y ago
• DDogma BLYAAAAAAAAby 76561198369844905Changes Dogma appear sound to Russian kid screams BLYAAAAAAAAAAAAAaAaaaAAAAaaaa bcz his minecraft house disappears meme Saw this video from channel taki_ and thought that it should be a mod. I'm streaming on Twitch btw~ You might aswell like my other mods for Isaac48.0k downloadsupdated 5 y ago
• TTouhou Reverie - Make Good Omissionsby 76561199075257239!! This mod does not support "Repentance+" DLC !! It doesn't mean the mod cannot work with 'Repentance+' DLC. In fact, the mod can run fine, but it has not been adapted to the new content and changes introduced by Repentance+. It is recommended to play this mod with REPENTOGON version 1.0.12e or...47.8k downloadsupdated 9 d ago
• VVine Boom Bombs IIby SprSnpr_Changes the bomb explosion sound to the Vine Boom sound effect. Didn't expect much going into this but honestly, it kinda works. This mod was made by request47.3k downloadsupdated 3 y ago
• [[AB+] Eevee!by BennyStatus Update from Benny The mod has, unfortunately, been cancelled for the foreeable future. There has been a lot of work put into the mod since the Repentance demo's last update, but due to mental health issues, I cannot comfortably continue development. Having a second coder on the team or me...46.5k downloadsupdated 5 y ago
• SSubaru Respawn Sound on Deathby 76561199844292366Adds instant Respawn and Re zero's Iconic Respawn Sound46.3k downloadsupdated 18 mo ago
• TThe Lockedby RyouThis mod adds a new character called The Locked! Unlock his hidden potential! The Locked starts off slightly slower, but he has 5 hearts! Unfortunately for him, he can only have soul hearts, however. Regular HP Ups give him a soul heart, though, so not to worry. This all changes, however, when yo...46.2k downloadsupdated 6 y ago
• [[AB+] Retribution - 109+ Itemsby XalumATTENTION RETRIBUTION HAS BEEN UPDATED FOR REPENTANCE GET IT HERE: !!! This mod will not function correctly without Mod Compatibility Hack !!! Retribution adds 109 147 brand new items to the Binding of Isaac - ranging from a feeble axolotl friend to a cursed pumpkin mask. Play as Icarus, who star...46.2k downloadsupdated 6 y ago
• BBalatro Jokers [Rep|Rep+]by CaMpeRWith Balatro Jokers mod you'll be able to enjoy your favorite jokers and the pack opening experience from Balatro! This mod adds the following content: -1 passive item! -1 Character! -24 Tags! -20+ trinkets -15+ pickups -15 DECK CARDS! -9+ planet cards? (Most of them with custom SFX) -ALL 150 JOK...44.9k downloadsupdated 10 mo ago
• RRune Roomsby 76561198374458982Enter the Rune Room, a cut room type planned for Antibirth, and claim your rewards! Rune Rooms A new room type that has a 20% chance to replace vaults. To activate the room's unique floor-wide effect, step on the 4 pads located in the room. Alternatively, the giant crystal can be blown up to spaw...43.8k downloadsupdated 21 mo ago
• YYouTube Thumbnail Rocksby PoondaedalinNow compatible with Mod Config Menu! Options: - Multiple Arrows - Vine Boom Sounds - "Dank Meme" Sounds (Can be toggled between Tinted Rocks, Super Secret Rocks, both, or neither) Well, I made a mod with a ton of effort put into it and it went over like a soft fart, so here's a meme mod that took...43.7k downloadsupdated 3 y ago
• ZZelda angel room (Prosper Fitness Blessing)by 76561199811310810replaces original angel music to The Great Fairy Fountain from The Legend From Zelda music used in a mod UPDATE 1.2 I've finally fixed all the bugs, and you can now choose between two modes for the mod: Mode 1: The music plays constantly. Mode 2: The music plays only when there is a Q4 item in th...43.5k downloadsupdated 3 mo ago
• TThe Binding of Isaac: The Devil's Harvestby TeamPROBIRTHIntroducing The Binding of Isaac: The Devil's Harvest MOD. Made by a team of elite The Binding of Isaac: Afterbirth+ modders named Team Probirth, this total conversion expansion mod is guaranteed to shake up the now stale meta of Isaac franchise forever by introducing wacky new groundbreaking con...43.4k downloadsupdated 10 y ago
• Rrandom blue lobsterby 76561199450244000Someone asked for this and I thought it was funny enough to make. Plays the loud ass dracula music and covers your screen with blue lobster. 1/10000 chance to happen every second by default, can be changed if you have Mod Config Menu43.0k downloadsupdated 21 mo ago
• MMelisby MaddogsPlay as Melis the Succubus, a demon with the ability to consume the souls of those she charms. You will start with flight and spectral tears, however you cannot shoot, as she has 4 other mechanics to play with: - A demonic aura that damages all enemies inside it and increases with Melis' range an...41.7k downloadsupdated 10 y ago
• DDeltarune Explosion - Remakeby EaveThis mod was heavily inspired and based off of the already existing "Funny Deltarune Explosion" mod. The original version is great, but the sprites seem to be scaled improperly, cut off at the bottom, and for some reason missing a few frames- As well as the mod itself missing a few sounds. This r...41.7k downloadsupdated 4 y ago
• UUlamby MaddogsPractice your aim with Ulam the Ranger, the first ammo-based character in The Binding of Isaac! Pierce your foes through with the arrows you fire from your trusty bow, charge up shots to increase the damage and accuracy of your arrows, and pick up different items to give them an elemental aspect...41.6k downloadsupdated 10 y ago
• RReverb Fart Meme Sound Effectby ashesMade as a request. It's exactly what you think it is.40.7k downloadsupdated 6 y ago
• AAngel Blade [AB+ ONLY]by micromarioFinally! A purely melee weapon in Isaac! It gives you a suit of armor, and an epic blade to slay your foes. It synergyies with over 60 items, most of which "enchant" the blade, giving it a new and special apperance. *I've update the mod (almost 2 years later)* Issac now continues to fire after pi...39.9k downloadsupdated 8 y ago
• SSkill Issue [Rep|Rep+]by I am a Womp Rat ©You know that damage you took? Yeah that was your fault. Features: Small chance that the game will berate your skill when you take damage (see screenshots) If you listen closely, the game may call you a loser when you die :) Toggleable settings if you have the Mod Config Menu Mod Picture credits...39.8k downloadsupdated 10 mo ago
• DDamocles Cinematic Deathby 76561199108106508Replaces the Damocles death with a full cinematic Created together with: Aksel The sound and voice by: Robo Pof39.2k downloadsupdated 4 mo ago
• DDBZ teleportby 76561198825922892Changes the teleport sound to Goku's instant transmission39.1k downloadsupdated 4 y ago
• DDoki Doki Repentanceby CrashpunkThis is an overhauled version of the original DDLC Isaac Mod for AB+. Current Version: v3.5.2 REPENTOGON is not required but highly recommended! 4 playable characters with unique transformations Unlockable Achievements (REPENTOGON Only) Tainted characters with exclusive Pocket Items 5 Active Item...38.2k downloadsupdated 3 mo ago
• GGlareby CodeRedThis mod adds a brand new character: Glare! Glare comes equipped with a sword, which is impaling his head. Instead of firing tears he drops the sword into the ground. When the sword lands, it deals damage in a small area around it, and fires a burst of his tears in every direction. Activating the...38.2k downloadsupdated 5 y ago
• YYSDby 76561198448106326!!!warning!!! This mod modifies the ending after defeating final boss "the Beast". If you have not yet defeated this boss, please disable this mod and experience the correct ending first before enabling it. Added a new character "Ysd" and his tainted version. Ysd: Ysd doesn't need to be unlocked....38.0k downloadsupdated 13 mo ago
• HHeaven's Call [Solar Update](RGON)by UltrinikDO NOT HAVE INSTALLED OLD HEAVEN'S CALL VERSION!!! THIS MOD REQUIRES TO FUNCTION Check Isaac Guru's page for more detailed information Follow Heaven's Call on Twitter Mirror download for manual installation Play Heaven's Call Suika 13 new boss battles await your challenge! 1 FINAL BOSS! 10 Challe...37.8k downloadsupdated 14 mo ago
• ZZach [10+ Unlocks]by 26 years of gooning laterZach Death and the dice level all distinctions! Zach is a compulsive gambler - every room he clears grants him a poker chip! He can spend the stack of chips to roll his lucky pair of dice: Snake Eyes. Rolling the dice can grant boons such as stat upgrades, pickups and perks to improve future roll...36.9k downloadsupdated 5 y ago
• LLost and Forgottenby ENFOR!!! Lost and Forgotten requires Stage API to work properly !!! !!! Repentogon is NOT required but it's highly recomended !!! This mod is a Repentance port of the original Lost and Forgotten for Afterbirth+ with double the amount of features, improved art and performance. o Features o 100+ items 2...36.8k downloadsupdated 16 mo ago
• Bbob-omb battlefield mirrorby TrujiThis mod replaces the mirror in downpour with a recreation of the Bob-omb Battlefield painting from Super Mario 64. The music is also replaced with the Throwback Galaxy theme from Super Mario Galaxy 2 (Orchestrated version of Bob-omb Battlefield). If you're using music replacement mods then you m...36.4k downloadsupdated 5 y ago
• IIncreasing Pitch (Shepard Tone)by IsaacGuruThis mod increases the pitch of sound effects when repeatedly picking up pickups. What this means is, the more pickups of the same type you pick up in a short amount of time, the more their pickup sound will increase in pitch. The effect applies for the following pickups: coins, keys, bombs and h...35.9k downloadsupdated 5 y ago
• BBoss Butch! (13 new bosses)by PixelPlzBoss Butch adds 13 brand new bosses to kick your ass in unique and surprising ways! If that's not enough for you, then you can also test your might in the Boss Butch challenge, featuring all of the new bosses! Also included is a special Boss Butch Bestiary™, where you can learn more about your fa...35.6k downloadsupdated 4 mo ago
• [[SHAW! Update] Hollow Knight Spidersby 76561199652670853Replaces Level 2 Spider and Spider with Hornet and The Knight respectively. The mod is inspired by Hornet's spider moves with the Scuttlebrace Tool, which apparently became a meme. Idea: Hushик Sprites: CoolSkeket34.8k downloadsupdated 12 mo ago
• WWinston says Hi [SFX]by machasinsThis mod simply plays a Winston voiceline, "Hi There", whenever the trinket Monkey Paw appears. Does not include Winston resprite, go here for that. Issues? Report it here or in the comments of this mod. Can be configured with Mod Config Menu to adjust when the sound plays and how loud it is. Now...34.7k downloadsupdated 3 y ago
• [[RGON] Arknights : Terra, a Journeyby 76561198976289600Arknights : Terra, a Journey A crossover content mod inspired by Arknights, bringing new mechanics, encounters, and Terra-flavored content into The Binding of Isaac. Requires Repentogon to play! Arknights : Terra, a Journey is a content-rich mod that introduces original items, trinkets, enemies,...34.5k downloadsupdated 12 d ago
• TThe Gardenby Doug Bowen== Features == For answers to common questions, please see the FAQs and Known Issues under the Discussions Tab * New room: The Garden * 13 new passive items! * New challenge: Genesis * New curse: Curse of Mortality * New bosses: The Serpents * New transformation: Deceiver! * New music * New sound...34.0k downloadsupdated 10 y ago
• SSenator Greedstrong modby LEFRUTITINew way to experience greed game mode! Checkout "Senator Greedstrong mod" you will get: gorgeous ultra greed resprite, new ultra greed sound effects and new background music! Mod сompatibility HardMode Major Boss Patterns Enhanced Boss Bars33.3k downloadsupdated 5 y ago
• Mmetal pipe sound effect for keysby 76561198861775051Have you ever wanted the keys from the hit game The Binding Of Isaac: Rebirth to sound like complete dogschit? no? too bad 10/10 - ign "it has a little something for everyone" 10/10 - bob " i love it" uhh go dowload now33.1k downloadsupdated 4 y ago
• HHotel Mario introby kittrzreplaces the intro cutscene with a recreation of the Hotel Mario intro "Dear pesky plumbers, YOUR SON HAS BECOME CORRUPTED BY SIN."32.3k downloadsupdated 4 y ago
• BBalls of Steel Replacement Voiceby Fragrant FlaaffyI think we all knew this one was coming right? :)31.6k downloadsupdated 10 y ago
• SSoulja Boy Coinsby LycaChanges coin pickup sounds to samples from the hit song "Crank That" by Soulja Boy now on iTunes™! Inspired by RealGuyWhoIsReal's Tainted Keeper Video:31.5k downloadsupdated 4 y ago
• BBumbarioby HengusMEver thought to yourself, "Gee, Bumbino's charge attack looks an awful lot like Wario's, huh?" No? Just me? Well, introducing Bumbario! The new, REVAMPED version of Bumbino! It features some of Wario's classic characteristics, suave mustache, voice and hat! FEATURES: *New sprites *Smashingly good...31.4k downloadsupdated 5 y ago
• SStarFall | 35+ Unlocks & More!by 76561198447262219Shooting stars can make a wish, right? Just imagine how a Starfall can make us all happy... 2 new characters 46 new collectible items 20 new trinkets 4 new consumables 2 new hearts 1 new chest type 2 new challenges (With unlockables!) 1 new monster 40 new rooms Tons of synergies! Stay tuned to se...31.0k downloadsupdated 3 y ago

740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.