Mods / Sound EffectsThe Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth sound effects mods
Everything filed under sound effects by its own author, ordered by how much it is used.
740 sound effects mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
740 sound effects mods
- The Man who Lost the World (Metal Gear Lost)by Бедолага ОлегMod that changes the Lost to the Man who Sold (or lost, in this case) the World, a.k.a. Naked Snake from Metal Gear game series. Also changes the Tainted Lost to Venom Snake and adds a snippet of the hit song "INVISIBLE" by Duran Duran whenever you lose a mantle. Hope you like it! I'll try to mak...22.2k downloadsupdated 19 mo ago
- POTATO PACK 2: Game Tweakersby ☢ Nato Potato ☢A collection of the mods I've made that modify the game mechanics, most of which are totally customizable using the Mod Config Menu. The pack includes: No Health Cap, No Pickup Cap, No Pocket Cap, No Curses, No Costumes, No Empty Pedestals, Custom Starting Items, Custom Base Stats, Custom Stat Ca...21.9k downloadsupdated 11 d ago
- cat bombsby 76561198994593714completing the cat pickup trio... - replaces every bomb with (un)canny cat, including troll bombs - also replaces bomb sfx incompatibilities: - (troll) bomb resprites (duh) - little horn/big horn resprites (due to their spritesheets having been edited)21.8k downloadsupdated 2 mo ago
- Spirit Sword "SPEEN" Soundsby SkiiveChanges Spirit Sword spin sounds to "SPEEN!" Credit to Vinesauce Vinny for the voice clips. Also shout-out to Albino for using this mod in his recent video: <3 This mod edits the following files: \resources-dlc3\sfx\sword_spin1.wav \resources-dlc3\sfx\sword_spin2.wav21.6k downloadsupdated 6 y ago
- Character Hit Soundsby MoltenCharacter Hit Sounds Replaces the boring default hurt and death sounds for some characters with alternative ones, such as Apollyon falling apart, ??? gasping, or Forgotten's bones cracking, making your skill issues feel fresh and unique. Configuration If Mod Config Menu Pure is installed, it can...21.1k downloadsupdated 15 mo ago
- Deltarune Soundtrackby Gay RatSoundtrack from Toby Fox's game, Deltarune REQUIRES SOUNDTRACK MENU MOD|| Compatible with Jukebox Mod This soundtrack menu mod consists of songs from chapters 1-4 of Deltarune! Please let me know if you come across any issues! -------------- Original OST by -------------- Toby Fox Lena Raine - Ar...21.0k downloadsupdated 15 mo ago
- 九九语音包by 1969 [bilibili live]不是什么专业的东西，就是个娱乐用的mod 以撒400多个音效全部由1969纯口技重新配音 好像没什么要说的，直接上个预览视频吧： 我的B站个人空间 我的B站直播间 记得不要玩太久哦！容易头晕。 小可爱快来点赞加收藏！20.9k downloadsupdated 9 y ago
- Silent flies with Beelzebubby The_BESTolochThis mod makes friendly flies silent when you get the Beelzebub Transformation. Doesn't change sound of flies if you don't have Beelzebub.20.8k downloadsupdated 4 y ago
- OK LET'S GOOOO (floor exit)by ☆⋆-MitsuuuuuuuuIsaac will say "OKAY LET'S GOOOO" when exiting a floor that's it.20.6k downloadsupdated 3 mo ago
- Samurai's Bladeby Math-ManA familiar sword wielded by a well-known samurai can now be found in the basement (Yes, it is Muramasa from Metal Gear Rising: Revengeance, no this is only half a poop-post.) This mod works but many synergies are missing. There might also be are BUGS. Update (28/10/26): Fixed the blade being draw...20.5k downloadsupdated 8 d ago
- Rebirth Brimstone Soundsby teelReplaces repentance's brimstone sound effects with the superior, original ones from rebirth. Also affects lil brimstone's & tainted azazel's weaker lasers. This mod should be pretty compatible as well since it doesn't modify any xml files.20.5k downloadsupdated 5 y ago
- Tainted Item Charge Soundby fartsox64Plays a sound when timed-charge pocket items for tainted characters, such as Judas and Jacob, have finished charging. This is an accessibility mod to help players with limited field of vision, as it's often difficult to see the outline around the items change when the item charges.20.4k downloadsupdated 5 y ago
- Issac missing poster itemby Vyro OneHi guys,have you ever wondered "I want to get the lost,but how the hell can I get the missing poster?" With this mod you guys are starting with the missing poster (with issac character ) and u can get the lost To enable the mod u need to enable the mod and disable all the mods u have. Steps: Step...20.3k downloadsupdated 9 y ago
- Baphomet (22+ Unlocks)by 76561198411462825Now you can play as satanic symbolic figure! NOW WITH 24 UNLOCKS!!! List for Unlocks, items and trinkets: Or you can unlock all of the items by entering baphometgrandscheme to the console. List for some of the Synergies: Features: New dash ability with unique playstyle! New Rage ability! New Soun...20.2k downloadsupdated 17 mo ago
- [REP] Pre-Repentance Brimstone Soundsby kittenchillyThis changes the brimstone sounds back to their classic ones from before Repentance! Note that some brimstone sounds couldn't be changed due to there not being any original counterpart to them, but almost all of the sounds should be back their original.19.9k downloadsupdated 6 y ago
- Let's go Gambling! [RGON]by possombullAdds awesome sound effects to the game the likes of which the world wouldnt have been ready for 10 years ago. Sounds play in some capacity for: -slot machines -fortune teller machines (technically, only when they self destruct) -all the beggars -shell game & its evil twin brother -crane games -co...19.9k downloadsupdated 2 y ago
- Bonk SFXby TrickyPuddlesPlays the bonk sfx for the forgotten's bone swing! Based off of funni video xd.19.8k downloadsupdated 6 y ago
- Morphby MaddogsMorph Meet the Half-witted experimental shapeshifter created by Silas the mad scientist! Morph was a test subject for creating the ultimate being, able to take on the ability of any creature it encounters... but things didn't go to plan. Morph is not the brightest or the healthiest, meaning he ca...19.7k downloadsupdated 10 y ago
- Restored Collectionby 76561198374458982Relics thought to be lost have been found, and are now in the basement! Restored Collection is a collection items, pickups, and more, restored from Antibirth to Repentance, featuring 23 items and 1 trinket! Features 23 collectibles to discover, ranging from items cut from Antibirth to items based...19.7k downloadsupdated 1 mo ago
- Half-Life Scientist SFXby PootisVanPencerJust a little mod I made because of the Half-Life Memes. And when Isaac gets hurt or dies, well... Just hear it for yourself.19.7k downloadsupdated 7 y ago
- We Live in a Society (Joker Card)by 76561198336418482Makes it so when you use the "Joker" card the narrator says "We live in a society..." instead. Sorry for the wind noise, but that's just part of the original noise. If someone knows a way to make it better, let me know. Audio Source19.4k downloadsupdated 6 y ago
- Foxy Death on Damoclesby MoistyWhen Damocles starts to fall, Foxy from FNaF2 jumps at the player Inspired by 1/10000 chance for Foxy every frame mods for various games.19.2k downloadsupdated 10 mo ago
- Smash Bros Ultimate Announcer (VS Screen) [AB+ Only]by JSGBasically, makes an AI generated Smash Announcer voice spell the names of vanilla, and a lot of modded, bosses and characters. It's a thing I always wanted and noone made...so I just rushed it in a day as a self-imposed challenge. Oh, and, yes, Im still working on my other mod that you may or may...19.0k downloadsupdated 6 y ago
- LTG replaces intro voiceby 76561198369844905Replaces voice from above in intro scene with famous meme with Low Tier God KnowYourMeme Your life is nothing! You serve zero purpose! You should k*** yourself now! And give somebody else a piece of that oxygen and ozone layer, that's covered up so we can breathe inside this blue trapped bubble....18.9k downloadsupdated 4 y ago
- Oh no! Our Mantle!by RemiThis mod replaces the sound of Holy Mantle breaking with the sound of everyone's favourite broken table.18.9k downloadsupdated 5 y ago
- Silent Jupiterby 76561199051585835shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up shut up s...18.8k downloadsupdated 5 y ago
- [REP] The Binding Of Pokemon + Legends Expansionby 76561198429240276A MOD MADE WITH A LOT OF LOVE AND AFFECTION BY FANS, AND FOR FANS. This mod is the official sequel to "The Binding of Pokemon" from Afterbirth+ now available for Repentance. Contains characters and items from "The Binding of Legends" (Rebirth) and lots of community-contributed Pokémon content. If...18.8k downloadsupdated 3 y ago
- Playable Character - Belialby РусскийLast UpDate 2021.05.10 The mod was created for Afterbirth+ and does not work on Repentance This simple mod adds one character - Belial! Belial is a demon, in honor of him made items "Book of Belial" and "Eye Of Belial", and now Belial is playable character! Belial is a very powerful Demon, but he...18.7k downloadsupdated 6 y ago
- TaintedAzazelMoansby DarkSundoes as the name suggest, TaintedAzazel now moans when sneezing18.7k downloadsupdated 5 y ago
- Yara Yara Phonk for Good Items (Specialist Dance)by 76561199099254650Specialist Dance for Good Items but with Yara Yara Phonk replaced. -I need have installed Specialist Dance? No, the mod incluides the songs and the dances, if you have suscribed Specialist Dance you need turn it off. Using the mod: Thank you so much for all the love and if you have a problem you...18.6k downloadsupdated 29 d ago
- One Tear Manby Русский"Every enemy can be one shotted" Remake of the original One Tear Man by Sentinel Well..now when you find item "Cone Head", you will become Saitama! Thank you very much Spore64 for creating a good suit sprite. When you find item "Cone Head" * Will play theme from anime One Punch Man * You are invu...18.5k downloadsupdated 9 y ago
- Lucky! Effect for Secret Roomsby 76561199108689396/ A mod that does the little lucky (or stylish) effect from Paper Mario The Thousand-Year Door for successfully finding any (vanilla) secret room; normal, super and even ultra! If secret rooms are automatically revealed or visible on the map then they will not trigger the effect as they're not "s...18.5k downloadsupdated 21 mo ago
- Undertale Soundtrackby moldy_train2Updated for Repentance! Make sure to have the Repentance version of Music Mod Callback before using. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Replaces all music and jingles possible with the...18.4k downloadsupdated 5 y ago
- Smosh SHUT UP during ascentby garfieldChanges dad's "shut up" to the Smosh intro during the ascent.18.4k downloadsupdated 5 y ago
- Super Mario World Death Animationby XXL PizzaDeath animation and sound effects based on Super Mario World. Features: -Every Vanilla Character -Modded Characters: Elijah, Fiend Folio, Gaper, Tarnished Characters (Partial Support), Mei, Bertran, Steven, Job, Andromeda, The Deleted, Mastema, and The Hollow -Game Over Music from SMW -Music stop...18.1k downloadsupdated 3 y ago
- Skulls fucking perish on deathby 76561198390663903Makes the invincible skulls scream in pain when they die18.0k downloadsupdated 4 y ago
- Deep laboratories [REP]by MogumiDeep Laboratories is a full reskin of The Binding of Isaac: Repentance, giving a complete visual overhaul to stages, enemies, bosses and more in an alternative technological version! Warning: the mod is big! And it replaces most of the game sprites, so having too many mods may cause various visua...18.0k downloadsupdated 2 mo ago
- Arthas's phrases on Angel and Devil roomsby 76561199378627108Replaces original Angel and Devil rooms sounds to Arthas's phrases from Warcraft 317.8k downloadsupdated 3 mo ago
- the binning of isek: aferberts plussby Ao JonesiREPPENISS VERSION SOON MAYBE The Full Graphical Overhaul is officially back, and better than ever! One day, as Isaac descends to the basement once again, he notices that things are... off. Everything looks like his drawings or something far worse... This mod gives the entire game a new, interesti...17.6k downloadsupdated 8 y ago
- D!Edith (TAINTED UPDATE)by 76561199101563685As a result, this mod does not and will not work on Repentance+ until REPENTOGON is ported to it! Stiff as a statue, D!Edith's (not to be confused with the character with the identical design and name from Antibirth) gimmick involves being incapable of shooting tears while moving. Charging weapon...17.5k downloadsupdated 5 mo ago
- YOUR TAKING TOO LONG (Deltarune/Mom's Shadow)by 76561198411934155Replaces Mom's Shadow with Jackenstein's pumpkin from Deltarune Chapter 4, and changes all associated music and sound effects. Gotta mention Pyzzabox and Vern, who uploaded similar (and much higher quality) mods around the same time as this one, go check them out too! I guess great minds think al...17.3k downloadsupdated 17 mo ago
- Keeper's Balls [Vineboom and Voiceline]by machasinsThis mod simply plays a vine boom sound and the narrartor saying 'Balls' whenever Isaac encounters "Keeper's Sack". Can be configured with Mod Config Menu to adjust when the sound plays and how loud it is. Issues? Report it here or in the comments of this mod. Thanks to Lazy Mattman for inspirati...17.2k downloadsupdated 16 mo ago
- Hollow Knight Soundtrackby moldy_train2Updated for Repentance! Make sure to have the Repentance version of Music Mod Callback before using. Now works with the Jukebox mod! To see all tracks, including Repentance ones, subscribe to TeSLaSP2's version of the mod, which can be found here: Replaces all music and jingles possible with the...17.2k downloadsupdated 5 y ago
- Oh Hell Nah for Bad Itemsby The DrinkPlays "Oh my God Bro, Oh Hell Nah, Man WTF" meme sound effect for bad items. My first Isaac mod Sound is played when entering a room with an item that has Quality 017.1k downloadsupdated 3 y ago
- Cat for Good/Bad Pillby 76561199122359894You will see a holy cat whenever you eat a good or bad pill not compatible with mods that change player animations. Curse version:16.9k downloadsupdated 4 y ago
- ENA MOD (26+ Unlocks) [REP/REP+]by 76561198410624511ENA has come to Isaac with 26+ new unlockables! Featuring: 1 Character (+Tainted) 19 Collectibles 4 Trinkets 1 Pickup 1 Consumable 1 Machine 2 Challenges Turron! You can also unlock everything in the "dead sea scrolls" menu Isaacguru Wiki: REPENTOGON (not required) Mod works just fine without REP...16.9k downloadsupdated 11 mo ago
- Bruh dischargeby 76561198346109611I dont know why i did that, but yes (How tf did it come to Albino?)16.8k downloadsupdated 4 y ago
- sova na skakalkeby 76561199831705019SOVA NA SKAKALKE TikTok: kennnymc tgk: drochillnyakny16.7k downloadsupdated 4 mo ago
740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.