Mods / Sound Effects

• VVine and Farts Reverb SFX Replacementby fly_6Faith in humanity has been lost Because this mod replaces giant explosion sounds effects from Mama Mega! and Giga Bombs into Vine boom and farts sounds with reverb effect16.6k downloadsupdated 6 y ago
• AAbortionbirth Pack 2: THE HECKONINGby NarilliaWelcome friends to The Binding of Isaac: Abortionbirth Pack 2: The Heckoning, sequel to a total expansion MOD to defeat all other mods! Each item has been designed from scratch with all the care in the world to offer the ideal experience. This mod tops all other mods, EVEN the original Abortionbi...16.6k downloadsupdated 9 y ago
• [[REP] Adiósby GrandeI DID NOT MAKE THE ANIMATION!!! I ONLY CHANGED THE SOUNDS OF ANOTHER MOD!!!!! PLEASE CHECK OUT THE ORIGINAL MOD AT RETRO DEATH SOUNDS AS WELL AS SAMARIO, THE PERSON WHO MADE THE ORIGINAL ANIMATION!!!!!!! fade away into oblivion upon death sample text16.3k downloadsupdated 5 y ago
• SSpongebob disappointed sound for 0 quality itemsby 76561198372192441Code stolen from: Oh Hell Nah for Bad Items:16.2k downloadsupdated 2 mo ago
• RRagequit Animation (And sound)by 76561198447262219Changes death animation on all characters! Also adds own death sound, cutted verison of tyler1 scream COMPABILITY Mei Andromeda Bertran Arachna Fiend Folio Revelations Samael StarFall If you're a mod developer, you can simply add your animation! Just check main.lua file. Hope you like this mod! Bye!16.2k downloadsupdated 3 y ago
• CCute BabyBrim/Sneeze SFXby SkiiveThe new "sneeze" Babybrim-mechanic not "sneezey" enough for you? This is the mod for you! All 4 sound-effects are modified/overlayed with cute anime sneezes. Effects item "Hemoptysis" and Tainted Azazel (as he starts with the item) Credit to "grandisa" on MyInstants, this dude uploaded/cliped abo...16.2k downloadsupdated 6 y ago
• [[PVZ]GIGA DOOMSHROOM Explosionsby 76561199217547350Added a new "Doom-like" explosion animation to the GIGA Bomb. Textures and sound effects are sourced from PVZ (Ds) Explosions!,with the original game being Plants vs. Zombies DS version. Recommend to subscribe together to "enjoy" the explosive experience akin to "Plants vs. Zombies." There might...16.1k downloadsupdated 21 mo ago
• CCat Keys | Reskin for Keysby SlurpmeisterUnofficial sequel to Cat Coin. Replaces Keys with a (very funny) gif of a cat dancing. Contains: - Funny cat reskins for all key types - Resprite for the Mega Satan key + door16.1k downloadsupdated 1 mo ago
• CChronoscope (ZA WARUDO) [Outdated]by 『Sora』Take control of the world with this amazing timeless item! Gain the ability to stop time for all but yourself for a few seconds with this definately-not-a-jojo-ripoff item! 4 room charge. Now working with jojo character mods and brimstone! Blast and punch away! Also Mom's knife! Have fun shouting...15.9k downloadsupdated 9 y ago
• AAbortionbirth (OUTDATED, GET PACK 2)by NarilliaWelcome friends to The Binding of Isaac: Abortionbirth, a total expansion MOD to defeat all other mods! Each item has been designed from scratch with all the care in the world to offer the ideal experience. No refunds. So far, we've done 103 items, but soon enough I guarantee you our following li...15.9k downloadsupdated 9 y ago
• JJoseph Joestar and Hermit Purpleby CodeRedAdds a new character to the game: Joseph Joestar! Joseph Joestar is a JoJo character with a stand named "Hermit Purple." He attacks by whipping Hermit Purple in front of him for a thin AOE attack. How the attacks synergize: The attacks work by finding enemies hit by the vine, then spawning an inv...15.9k downloadsupdated 5 y ago
• PPS2 Eternal Heartby VickyChanges eternal heart pickup sound with the PS2's startup sound. Will also change other instances where this sound is used, like Isaac changing phases. Now comes with a preview, because I initially completely forgot about it like a moron15.7k downloadsupdated 5 y ago
• HHL2 Meat SFXby 76561198860147672This is a mod that changes a small handful of sound effects to the hl2 (and by extention source engine) meat thud sound effects. If a boss usually has some sort of drawn out death animation (eg monstro or gurdy), it likely has the thuds play during that.15.6k downloadsupdated 3 y ago
• TThe Skeleton Appearsby fly_6Replaces Skull Giantbook sprite and Death Card SFX to The Skeleton Appears thematic media15.6k downloadsupdated 5 y ago
• ZZiren Vocalist From the Brimstonesby Lamb"People likes music and i make music, show me your moves pink bald kid" Ziren is a alternative siren version where she is a metal singer (which metal genre?, idk) she has a incredible voice that changes, soft and cute, aggressive and heavy or both in the same time. i made this concept in Jan 6, 2...15.4k downloadsupdated 4 y ago
• FFurtheranceby anchikaiSUBSCRIBE TO THE NEW MOD! The Binding of Isaac: Furtherance is a modded expansion that adds a flavorful amount of new content! Features - 42 Passive Items - 26 Active Items - 20 Trinkets - 3 Characters w/ Tainted Counterparts: Leah, Peter, & Miriam - Unlocks for all Characters - Mod Config Menu S...15.4k downloadsupdated 4 y ago
• MMeme Fartsby Keeby☆All fart noises are replaces with meme farts15.4k downloadsupdated 6 y ago
• AAstral Vessel - Passive Skill Trees Customizable Character [BETA]by Ab AeternoAstral Vessel is a new character built from the Passive Skill Trees mod that you can customize. From appearance, to starting items, to powers gained from their unique skill tree. Comes with lots of support for mod items and costumes as well. Vessel begins as a faceless and mostly featureless char...15.2k downloadsupdated 1 mo ago
• GGruesome Deathby HoneyVeeThis mod replaces the death animation, and adds gruesome new sounds too. It should not me compatible with mods that already change the death animation and sounds, but it should work with modded characters. A little bit of a backstory The animation is a reference to a Reddit post, where someone ma...15.2k downloadsupdated 17 mo ago
• WWeird Route Jingle Crooked Pennyby 76561199192981243like, uh, hey, maybe things took a weird route right now... replaces the crooked penny sfx with the weird route jingle from.. deltarune...15.0k downloadsupdated 4 mo ago
• MMaxwell V2 (Cube Baby Resprite)by 76561198326126870Replaces the "Cube Baby" item sprites with Maxwell the cat. v1.3+: Also lets Maxwell play his silly little tune when kicked! ONLY WORKS IN REPENTANCE. (because Cube Baby didn't exist prior to Repentance...) Config How-To: This mod now uses the Mod Config Menu (tested with Mod Config Menu Pure) to...15.0k downloadsupdated 14 mo ago
• OOne Must Imagine Jacob Happyby DoggersMod which plays an instrumental version of "Me and the Birds" by Duster (Sisyphus meme music) for Tainted Jacob in his Lost form. Because we all know that we will restart our runs sooner or later. This mod features: * volume changing (It is affected by music slider. SFX as well...) * carrying ove...14.8k downloadsupdated 3 y ago
• OOAAAA Restart [AUUGHHH/Snore meme]by Dr. Vindictathe classic AUUGHHH plays as you hold R to restart and stops if you let go, endless entertainement and relief that your run might be complete trash but at least you get funny noise. If you want the sound to not fade in there's an older version of the sound called "OAAAAAA old" which you can renam...14.7k downloadsupdated 4 y ago
• TThe Binding Of Isaac: Reflashedby Gusanitopeluo-Please set "MaxRenderScale" to 5 or 4 in the "options.ini" document located in your binding of isaac save folder for true flash fidelity! -If you use Onedrive or the last method doesn't work then search for "options.ini" on the windows search bar. -Restart the game after the mod is installed. Ch...14.7k downloadsupdated 11 mo ago
• EEggman's Announcement Over Ascentby 1920 x 1080 16:9 WidescreenReplaces the dialog in the ascent with Eggman's announcement. Fun fact: I made this mod months ago, but couldn't figure out how to upload a mod the the workshop lol14.6k downloadsupdated 4 mo ago
• Ppvz trophy and victory jingle over challenge trophyby 76561198876704734replaces the challenge trophy with the one from plants vs zombies and also adds the pvz victory jingle when picked up14.6k downloadsupdated 3 y ago
• DDamn bird for dead birdby skwidekKill sfx was added thanks to TheAlex63! Thank you Alex now everyone can enjoy this beauty of a mod much more! DAMN!!! bird replaces the dead bird sprite DAMN!!! didn't expect that this simple replacement would get 6.8k downloads. It's my first attempt to modding isaac and i made this for ♥♥♥♥♥ an...14.5k downloadsupdated 15 mo ago
• SSamsung Shieldby NeuFlaasChanges Holy Mantle shattering sound to Samsung Notification -not sponsored ( yet? )14.5k downloadsupdated 5 y ago
• DDogma Brimstoneby 76561198855158338Replaces the graphics and sounds of all player-spawned brimstone beams with Dogma's static lasers! For a standalone item version of this mod, check out Dogma's Truth!14.4k downloadsupdated 20 mo ago
• AAntibirth Runesby 76561198374458982In the Antibirth mod, there were 4 runes that were cut from Repentance along with 2 more runes that were unused. This mod brings them back! 𝐀𝐧𝐭𝐢𝐛𝐢𝐫𝐭𝐡 𝐑𝐮𝐧𝐞𝐬 Features EID support Features Magic Chalk, Rune Tablet, Andromeda, Epiphany, Fiend Folio, Rep+, Retribution, Rare Chests Support ____________...14.4k downloadsupdated 8 mo ago
• TTo be continued death musicby SamiTreseThis mod changes the death music with the song Roundabout from Yes. Works on repentance and afterbirth +14.3k downloadsupdated 10 y ago
• TThe Music of Undertaleby RuinSmith_HlitMusic of undertale mod, ported from modding of isaac, changes nearly all of the music from binding of isaac to songs from undertale, with some SFX's being replaced with iconic noises. =========How to have mods enabled======== this method is not truely a catch all, it wont get all the mods you wan...14.1k downloadsupdated 10 y ago
• HHardMode Major Boss Patterns(AB+ only)by DotThis is AB+ version of the mod, Repentance+ version is here: This mod adds new patterns and phases of major bosses in hard mode. Also involves some pattern enhancements, shields and resprites. This mod is still in development, bosses with new patterns or phases implemented are as follows. -The La...14.1k downloadsupdated 5 mo ago
• LLazy Mattman Screams For Good Itemsby ruberWOOOOW A mod that adds Lazy Mattman's scream for 4 quality items. There are 10 variations of the shout in the mod (which are played RANDOMLY, realistically). Enjoy and good luck! P.S. Special thanks to D1m7asis for help with the code14.1k downloadsupdated 3 y ago
• SSpider Man 94 metal pipe sound on the hitby 🎮-_MAX_-🎮Replacement sound of damage against Isaac with the sound of metal pipe from the cartoon Spider-Man 9414.1k downloadsupdated 20 mo ago
• FFunny Deltarune Explosionby 76561199065679212Replaces the explosion effect with the one seen in Deltarune. It also includes the same sound effect from the original game. 26/04/2022 This mod is not being supported at the moment, but don't worry, there's another version that fixes most of the problems this mod has. I strongly recommend checki...13.9k downloadsupdated 5 y ago
• WWhatsapp Dangleby Not CyanChanges that weird ass dangle whistle sfx for the good old based whatsapp notificaton sound13.8k downloadsupdated 6 y ago
• IIt's Going Down Now for Good items (DROP VERSION)by PeridarrenDISTURBING THE PEACE, LOOK INTO MY EYES Wanted a version where it starts at the drop instead? WELL HERE YA GO! The Specialist dance but instead it uses It's Going Down Now from Persona 3 Reload. Full song version If you wish to use it with Reaction Port Pack instead, someone made a mod that adds...13.7k downloadsupdated 20 mo ago
• DDaydream all Dayby 76561198402142170Let's step into this wonderful DAYDREAM, and experience items and characters that can only be imagined in your dreams! Features "Daydream All Day" is a mod with 100+ dreamlike new items, trinkets, and characters. All items are filled with unique effects, allowing you to experience infinite pleasu...13.6k downloadsupdated 15 d ago
• FFLESH PRISON over Moms Heartby 76561198420588728I thought it'd be funny ok. The mod changes the looks and sounds of It lives, as well as Mom's Heart fights. It will probably conflict with other reskins so be aware of that. Credits: FLESH PRISON as well as the music from ULTRAKILL by Arsi 'Hakita' Patala. p.s. Its my first ever mod for isaac so...13.5k downloadsupdated 19 mo ago
• DDogma Doblajeby MicaloxThe Binding of Isaac: Dogma con Doblaje Profesional al Español Latino Mod 1: Cinemáticas, Intro, Epilogo, y Dad's Note Doblados (¡Subido en mi perfil!) Mod 2: Dogma (Versión Actual) Mod 3: Píldoras, Cartas, Runas y otros. Este mod contiene: -Doblaje de cinemática post Dogma -Doblaje de Audios de...13.3k downloadsupdated 19 mo ago
• Vvottakoihamamforgooditemsby 76561199831705019COPY OF THE MODE SPECIALIST FOR GOOD ITEMS WITH CHANGED MUSIC!!! ORIGINAL MODE: Tuff mode votakopasan😎 TikTok: kennnymc tgk: drochillnyakny13.3k downloadsupdated 6 mo ago
• CCurse of the HMM (With SFX)by 76561199122359894Changes the red question mark to hmm cat Update: Now it plays sound effect when entering a treasure room with the curse13.3k downloadsupdated 14 mo ago
• IIsaac's Keyboardby anchikaiThis mod will no longer receive updates. Play Furtherance instead! Is R Key not enough for you, and you wish you could press all the various keys with an active item instead? Introducing, Isaac's Keyboard! This mod introduces 11 brand new keys to the game that all spawn in the secret room: Esc Ke...13.2k downloadsupdated 5 y ago
• WWhen the secret room is susby PotatoWhen the secret room is sus Changes the secret room jingle to amogus body sound.13.1k downloadsupdated 5 y ago
• $$19 fortnite cardby 76561198363305736Who wants it? -------- not supported. use instead13.1k downloadsupdated 5 y ago
• ((AB+) Genesis+ Music Packby BroskiPlays on ROG AllyIt is recommended that you use The Binding of Isaac Genesis+ with this Music Pack for most fitting experience. This music pack is a additional pack for The Binding of Isaac: Genesis+, It includes the latest custom soundtracks for people that prefer the custom music over the normal one. This pack...12.9k downloadsupdated 10 y ago
• KKissy Longlegsby KodaichiShe loves you (and it shows!) This mod makes Sissy Longlegs able to kiss you, that's basically it. Since the ideal spider-kissing experience varies between individuals, there are various configurable options and features. Detailed Features: + Sissy gives kisses. One for free when you get her, and...12.9k downloadsupdated 5 y ago

740 sound effects mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.