The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth tweaks mods
Everything filed under tweaks by its own author, ordered by how much it is used.
1,627 tweaks mods, most downloaded first ยท newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.6k tweaks mods
- Segmented Mausoleumby 76561198374458982(WARNING: This mod is still unfinished) The segmented Mausoleum feature from Antibirth has returned! ๐๐๐ ๐ฆ๐๐ง๐ญ๐๐ ๐๐๐ฎ๐ฌ๐จ๐ฅ๐๐ฎ๐ฆ ๐๐๐ ๐ฆ๐๐ง๐ญ๐๐ ๐๐๐ก๐๐ง๐ง๐ ๐๐ข๐ซ๐๐๐ญ๐จ๐ซ = kittenchilly ๐๐จ๐๐๐ซ๐ฌ = kittenchilly, im_tem ๐๐ฅ๐๐ฒ๐ญ๐๐ฌ๐ญ๐๐ซ๐ฌ= kittenchilly, im_tem, Sillst 4Grabs, Aether, Akad, ALADAR, Andre Doruk, Blind the Bound Dem...10.2k downloadsupdated 4 y ago
- Damocles Slabby big robotcompletely removes damocles from the game. replaces it with a functionally identical 2 ton slab of stone based on that one meme from ifunny/reddit10.2k downloadsupdated 3 y ago
- Giga-Explode on (True) Deathby - coolpew -Dying makes you explode BIG! Use discretion if you think this mod will trigger any unlocks.10.2k downloadsupdated 17 mo ago
- HEHEHEHA MANTLEby 76561198390663903Replaces Holy Card and Holy Mantle with Mr Royale from Clash Royale (Clash)10.1k downloadsupdated 4 y ago
- Realistic Black Holeby UltrinikAdds a REALISTIC black hole distortion effect to the Black Hole item effect and the Void stage portal. To toggle on/off the two effects, write in the console, "RBH Item" or "RBH Void". This is a standalone version of the black hole effect present in the Heaven's Call mod.10.1k downloadsupdated 2 y ago
- StatAPI 2.0by ใSoraใProps to Oroshibu for the cool icon art! If you get any errors or bugs, report them in the comments below or start a new thread! Modding support tool designed to fix some of the issues with the modding api's current limited stats system. If you decide to use it, a credit would be cool (albeit not...10.1k downloadsupdated 8 y ago
- Shut Up, Mom and Dadby Ataristic!! THIS MOD IS NO LONGER NECESSARY IN REPENTANCE+, edit your options.ini to mute ascent voice lines. The mod will be deleted from Steam Workshop eventually. !! "I removed them. They're gone. Just get over it!" "What do you mean? What do you mean they're gone? HOW COULD YOU HAVE REMOVED OUR CAMPY...10.1k downloadsupdated 23 mo ago
- Lost turns Hearts into Wispsby Iris HeartLost and Tainted Lost can now pick up all vanilla heart types. For every 2 red hearts picked up, Lost gains 1 red wisp that shoots alongside Lost, but cannot block anything and deals no contact damage. Expires upon traveling to the next floor. For every soul heart picked up, Lost gains 1 blue wis...10.1k downloadsupdated 4 y ago
- Nice Cockby 76561198935929219Replaces the 'I Found Pills' sfx with Nice C*ck This mod may not be compatible with other mods that change the names of cards/pills, such as "Balls With No Steel", etc. Just to be safe, Repentance only. If this mod doesn't work, check the pocketitems.xml files of other mods and ensure they're not...10.0k downloadsupdated 3 y ago
- Schizophrenic Mantle - Random Mantle Breaksby dedPlays the mantle break animation and sound every 2-8 minutes while playing tainted lost10.0k downloadsupdated 2 mo ago
- True Splitscreen Co-opby DeadInfinitySingle screens begone! Now you and your friends can play on your own individual sections of the screen as True Splitscreen Co-op comes to Afterbirth+! With up to however many players the game supports, move around the screen, and have fun! You can pick up items, trinkets, cards, and pills! Config...10.0k downloadsupdated 8 y ago
- Danger Ahead! - Warnings on cleared rooms with obstaclesby 76561198993684021Have you ever accidentally walked into a spike rock and lost a tainted lost run you were 50 minutes deep into? Well this mod adds warnings for already cleared rooms that contain obstacles you could accidentally walk into! This includes spikes, bombs, red poop, spiked rock, fire places, brimstone...10.0k downloadsupdated 3 y ago
- Co-op Fixesby NotAnAndroidNormally, Tainted ???'s poops and Esau's entire UI only show up for Player 1, which makes Tainted ??? and Jacob & Esau pretty much unplayable for anyone else. This mod fixes that. The custom UI can be turned off for everyone, on for everyone, or on for everyone except Player 1 using the Mod Confi...10.0k downloadsupdated 4 y ago
- Mommy's Underwearby ViscerA10.0k downloadsupdated 5 y ago
- Accurate Character Select - eyeguy's Character Portraitsby ConnorsseurAdds the four missing stats to the character select for all characters, adds missing items, fixes spelling errors, and makes stat tallies much more consistent and accurate to the character's actual stats. This is the Repentance version of the mod! Click here for the Afterbirth+ version. Note: Onl...9.9k downloadsupdated 4 y ago
- Filmos's Easy Modeby AurifThis mod adds the easy difficulty (replacing the normal difficulty). When playing on easy you gain additional starting items, but you won't get these items on any other difficulty! More information (including the full list of new starting items) can be found on my website:9.9k downloadsupdated 10 y ago
- mulligan respritesby 76561198876704734does what it says on the tin commissions still open9.9k downloadsupdated 3 y ago
- Mystery Egg Stagesby 76561198340068660Mystery Egg now gives an indication of rooms cleared! Each stage has a separate sprite, corresponding with what charmed enemies are able to be spawned for the amount of rooms cleared without damage. This mod does not change the function of the item, all enemies able to be spawned as per room clea...9.9k downloadsupdated 11 mo ago
- There's More Optionsby noxterynOverview All Boss Rooms and Treasure Rooms spawn two items instead of one, and you have the option of choosing which one to take. Basically, it's like starting every game with More Options and There's Options. Compatibility Should be compatible with everything.9.9k downloadsupdated 9 y ago
- better pootersby 76561198443814292pooters now move quickly over rocks!9.9k downloadsupdated 4 y ago
- Keeper Coin tears(vfx only)by Chinpokomon_You still poor but now you look cool. Now playing as a Keeper your tears will be replaced with coins(head of the keeper effect) BUT it is a visual effect only and these tears will not produce any coins.9.9k downloadsupdated 5 y ago
- Fancy Crown Trinketsby TerraWisprResprites Cracked Crown, Bloody Crown, Holy Crown and Wicked Crown to match damagaz's Fancy Crowns. since the sprites are based off of Fancy Crowns i will delete this mod if damagaz does not approve of it9.9k downloadsupdated 2 y ago
- cool ANGEL STATUE modelby 76561199192206099This mod changes the angel's model :39.9k downloadsupdated 4 mo ago
- Sacrificial Altar compatibility for Modded Familiars and Items!by fedewThis mod allows sacrificial altar to sacrifice modded familiars and spawn modded items from the devil pool! Built-In Compatibility This mod has already built-in compatibility for the familiars from these mods: Revelations (ch.2) Deliverance Lost and Forgotten IPECAC community mod Retribution* Fie...9.8k downloadsupdated 6 y ago
- Status Icons, Greed Button, and Sticky Nickel Reduxby FerpeResprites a bunch of stuff to make it look a bit better! Another commission for vinnyp316! Reminder you can buy your own commission by dming me: Ferpe#4305 You can pick and choose what to use by subscribing to these versions instead of this one: Sticky Nickel Redux - Status Icons Redux - Greed Bu...9.8k downloadsupdated 4 y ago
- Sound Effects for Bad Itemsby Zeta ArcadeSound Effects for Bad Items This mod plays a variety of funny sound effects when you encounter bad items. To go one step further though, this mod can look at your character/inventory to determine IF an item is still bad for you, and lets you fully customise the sound effects and items. Don't agre...9.8k downloadsupdated 4 y ago
- Min-Min Respriteby DarianChanges Min-Min's sprite to look similar to her cut and early concept, Maid in the Mist Changes all the graphics associated with Min-Min's boss sprite, as well as the Vs. screen graphic Should be compatible with Enhanced Boss Bars:9.8k downloadsupdated 4 y ago
- Start with Pyromaniacby BarjuhStart each run with Pyromaniac Collection with all my Start with mods :9.8k downloadsupdated 4 y ago
- Stat and Achievement Shenanigansby StlkngneThis mod requires REPENTOGON. Press the tilde key to open the new debug console and menu. There's a new Shenanigans option that will let you view/modify stats and achievements. The data here is presented very simply. Look here to find out more information about each of the stats. Look here to fin...9.8k downloadsupdated 2 mo ago
- The Zapperby โข Nato Potato โขThe Zapper allows you to aim and shoot with the mouse, giving you 360 degree aiming, without making you constantly shoot like marked and without needing you to fiddle around with any game settings, it also gives tears up. While the Zapper is held a target will appear in the room which will follow...9.8k downloadsupdated 2 y ago
- DOOM in Isaac!by PoondaedalinWarning: This mod may not be suitable for people who are sensitive to flashing lights or effects! If you want to play the first level with mouse look/firing, click here! (note: just the first level) "Can it run DOOM?" "Yes, yes it can." "...sort of." This mod contains a few levels of a DOOM/Wolfe...9.8k downloadsupdated 15 mo ago
- AB+ | Detailed Respawn | Link for repentance version in the descriptionby 76561198367241059This version is for AB+. Repentance version Detailed Respawn lets you know what respawns you have in the correct order they will activate. It also shows you how many lives you have left from 9 lives and the chances of respawning for respawns based on chance (Guppy's Collar and Broken Ankh). You c...9.8k downloadsupdated 7 y ago
- Mom's Dressing Table [OLD]by SinstharUse Mom's Dressing Table to clean and customize the visual of Isaac ; It shows up in the first room in each floor and, when you use it, it randomly choose 3 or 4 appearances among your currently held items, wiping all other (the appearances, not the items !). Repeat the procedure as many times as...9.8k downloadsupdated 10 y ago
- Extra Goreby ZERBI-XCVIIDescription Extra Gore: more blood, more gibs and bigger enemy explosion for a better slaughter experience! How it works When enemies are killed, they explode into gibs/blood thanks to a combination between the effects of the special seed "BLOO OODY" and the effect "EXTRA_GORE". In addition: - wh...9.7k downloadsupdated 22 mo ago
- Start with Soy milkby BarjuhStart each run with Soy milk Collection with all my Start with mods :9.7k downloadsupdated 4 y ago
- Random Markiplierby 76561198884616821The game randomly starts the audio of the first Five Nights at Freddy's Markiplier video in it's entirety (except most of the outro song) when in-game. It should not play it while in the menu or while the game is paused, although if it starts playing it will keep playing until either the entire s...9.7k downloadsupdated 3 y ago
- virtual sin forgiveness (revelation laser sound replacement)by 76561199121244854I absolve you of your sins *holy death ray* You have been forgiven replaces the holy laser sound effect used by the Revelation item and angel minibosses (Uriel and Gabriel)9.7k downloadsupdated 3 y ago
- Payday (Unlock Keeper)by nicoSpawns donation machines plus cash pickups to easy unlock items on each character and to unlock Keeper.9.7k downloadsupdated 5 y ago
- Cute Beggarsby WeebyAre you tired of seeing those bald-headed beggars begging for your items and health? Well no more, now you can give away your items to beggars that are much cuter! I would totally give away all my items (and health) to them anytime, and you should too! Now includes the DLC beggars, such as the ba...9.7k downloadsupdated 4 y ago
- Femboy Pootersby lesserStarFemboy hooters pooter9.6k downloadsupdated 5 y ago
- Family Guy Stage Transitionsby super hard shadow on motorcycleSound and image from Family Guy added to stage transitions9.5k downloadsupdated 16 mo ago
- Invincibilityby GrimeliosMakes the player completely invulnerable to all damage. This makes sacrifice rooms unusable. This mod is slightly different from debug invinciblity (activated through the command "debug 3" through the in-game debug console) because this mod also disables damage animations. Quick note: I don't cur...9.5k downloadsupdated 10 y ago
- DelkisserUwUby 76561199661094703(English): This mod was inspired by this other mod: I seriously can't believe the effort I put into making Delirium Boykisser. Boykisser is love, Boykisser is life. (Espaรฑol): Este mod fuรฉ inspirado por este otro mod: (Es el mismo link que el de arriba, no lo voy a pegar dos veces) En serio no pu...9.5k downloadsupdated 4 mo ago
- Jacob and Esau Share Itemsby DevNo Twin Left Behind Jacob and Esau now share every item (active and quest items excluded). If one twin picks up an item, the other gets it too. No more deciding who gets every pedestal! Balanced To compensate for the doubled items, both twins have their stats reduced by 35% (each stat is configur...9.5k downloadsupdated 2 mo ago
- Another Planetarium Resprite Modby 76561198345870300Yep. Another one of these again. Gives the Planetarium items a bit more flair by editing their sprites to resemble their abilities in some way, shape, or form. Might do this with the rest of the "symbol" items, like the Zodiac items, Brimstone, etc.9.4k downloadsupdated 3 y ago
- Cutest Blood Puppo!by An Emo CowBlood puppy is cute, yes. But what if blood puppy was even cuter? And actually looked like a puppy? This visual mod makes blood puppy the pinnacle of cuteness! What a good puppo!9.4k downloadsupdated 5 y ago
- The Endless Room! (Challenge) [AB+]by JSGInspired by the old Spidermod survival mod, I bring you my approach of an endless room of constant mob-spawning mayhem!. Defeat waves and watch as the number and difficulty of the mobs/bosses increases, with several items to guide your way. How to access the endless room?: It's a custom challenge...9.4k downloadsupdated 10 y ago
- Genesis+ Septic Shock!by budjmtSomething smells funny beneath the Caves... After over 2 years, let's go to the Septic! - Septic is back and in the best shape of its life! It's been ported to the newer StageAPI for greatly enhanced stability and performance. - To access the floor, go to Ch 2 and look for a greenish rock. - The...9.4k downloadsupdated 7 y ago
1.6k tweaks mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

