The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth tweaks mods
Everything filed under tweaks by its own author, ordered by how much it is used.
1,627 tweaks mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.6k tweaks mods
- Uranus Fix [Mostly obsolete for Rep+]by RoaryHave I became "that planetarium items guy" by now, huh?.. Anyways this fixes that Uranus messes up ~60% of on-kill effects. For Repentance+, fixes: Goldened enemies not dropping coins upon being ice-freezed. (Midas' Touch, Eye of Greed) For Repentance, fixes: Goldened enemies not dropping coins u...9.4k downloadsupdated 18 mo ago
- Neko Tainted Bethby moth lover ari|| This is a "slightly less" beta mod that turns Tainted Bethany into a catgirl, with a cat book and cat wisps. || \\ Coming Soon: Finishing the different skin colors of T Beth, Fixing animations Making the cat ears look better Better workshop page Generally making this mod less ♥♥♥♥ Remaking the...9.4k downloadsupdated 5 y ago
- Aggressive Donationsby KingBobsonSmall mod that lets blood banks take donations from a slightly broader clientelle. Monsters touching a blood bank will take some damage and activate the machine. Mod idea by stewartisme!9.4k downloadsupdated 5 y ago
- Isaac On Twitch Reloadedby VirtualZer0Allow your audience to participate in the game! This mod gives you the possibility to connect your Youtube and Twitch chats, giving your viewers the ability to vote for what's happening on the screen. Features - Events Viewers can choose special events that have different effects on your run - Su...9.3k downloadsupdated 5 y ago
- EA Greedby 76561199102215533This mod shows the real site of EA...9.3k downloadsupdated 2 y ago
- Fair Co-op Items (Online)by ArtuurIMPORTANT REQUIREMENT To use this mod in online multiplayer, it is strictly required to have Isaac Online Modded installed. MOD CONFIGURATION & DESYNC WARNING To customize this mod's settings, you need to install Mod Config Menu - Impure. CRITICAL ONLINE INSTRUCTIONS: ALL players in the lobby MUS...9.3k downloadsupdated 29 d ago
- [AB+ Only] cHUD2.3 Liteby ConnorsseurHave you ever found yourself unsure of what items you picked up earlier in your run, or unsure of what it was that killed you? Well then cHUD Lite is perfect for you! It colors each and every item, enemy, and boss portrait in the game! Yay, colors!!! This mod is only compatible with Afterbirth+....9.3k downloadsupdated 6 y ago
- Better Challenge Roomsby NiroHarder challenge rooms + much better rewards! This mod makes challenge rooms harder by spawning a harder set of enemies. After you clear the challenge room you get a random item! If you clear the challenge room without taking damage, you also get 2 rare pickups! You can decide how many items and...9.3k downloadsupdated 4 y ago
- [REP] Your Favorite Familiar Mod - Baby Reskin modby peasThis mod reskins most familiars in the game to be consistent with one another, and a lot more adorable! There are still some missing familiars that need reskinned, so this mod will probably get updates in the future. Enjoy! Also, check out Lifebar if you're looking for another reskin mod to go al...9.3k downloadsupdated 5 y ago
- tbh as blood puppyby toaster bath bombsreplaces blood puppy with tbh/autism creature/yippee update 1: remade level 1 and level 2 sprites9.3k downloadsupdated 4 y ago
- Ultimate Random Character [RGON]by PixelPlzImprove your random runs with the ULTIMATE random character mod The mod is customizable and works with most other character menu mods! REPENTOGON is required for the mod to function! The mod makes several improvements to the random character option: Chooses from both regular and tainted character...9.3k downloadsupdated 11 mo ago
- Start with D6by BarjuhStart each run with The D6 Collection with all my Start with mods :9.3k downloadsupdated 4 y ago
- Gamma Auto-Adjustby bequirtlefor too long, we have had to choose between horrible darkness, or horrible washed-out colors. im NOT going to take it anymore!! This mod automatically adjusts gamma depending on the environment. Compatible with Mod Config Menu if you don't like the default settings: Currently affects all of the f...9.3k downloadsupdated 2 y ago
- [AB+/Rep] FUCK THIS ROOM IN PARTICULAR+by LeftieTested on Repentance only, but should be fully compatible with Afterbirth+ as well. Originally meant to remove one specific blue spike trap room from the Depths/Necropolis/Dank Depths, this mod removes all rooms with blue spike blocks that I consider unfair. Which is, like, 90% of all rooms with...9.2k downloadsupdated 5 y ago
- Intrinsic Babylonby 76561198412573006What it do? This mod replaces Eve's Babylon starting item with an intrinsic version, similar to how The Lost's Holy Mantle works. But why? This prevents Eve's main gimmick from being removed or rerolled, making the character exactly 3% more unique. Credits ratratrat: Mod Conceptor/Programmer Ferp...9.2k downloadsupdated 3 y ago
- Timed Active Icons (Full Collection)by bethanw10Shows an indicator above the player's head when they have an timed active item (e.g. The Candle) that is charged Mod Config Options added for enabling/disabling, changing the style of the icon, and for ignoring primary slot items or pocket items, making the icons transparent or toggling individiu...9.2k downloadsupdated 2 y ago
- Boneball Bombingby MaddogsFeatures a unique challenge where you are tasked to play baseball with bombs! You are given a choice of 4 bomb-synergy items at the start of the run, take one and get ready, batter up! Press a direction to throw a bomb, then press again to smack it! Have fun!9.2k downloadsupdated 9 y ago
- Better first floorby PetergenicsI got really tired of pressing r and not checking the first item room of every seed, and the other better start mods that i found in the workshop are op as fuck so i made this mod. ADDED MOD CONFIG SUPPORT What this mod does: 1- remove curses on the first floor (does not remove curse of labyrinth...9.2k downloadsupdated 5 y ago
- Azazel Full Range Brimstoneby infernalthingA mod that gives Azazel full range Brimstone. Known bug: Azazel doesn't use his charging animations for unknown reasons. I have no idea how to fix this :(9.2k downloadsupdated 10 y ago
- Antibirth Stylized Found HUDby fly_6Important! You should install HUD API for mod functionality! And in order to select this HUD, press H, or you can try install Mod Config Menu for HUD API This mod changes font and stats sprites for Found HUD, which were present in the Antibirth modification and soonly will appear in Repentance ex...9.2k downloadsupdated 6 y ago
- [FIXED IN VANILLA] TMTRAINER Progression Fixby shenanigansThis mod is no longer required as TMTRAINER no longer removes progression items! If installed, it will give unnecessary duplicate copies of them. This mod makes the game give you story-related items for progression if you are holding TMTRAINER: This means that: You get the Polaroid and Negative a...9.2k downloadsupdated 5 y ago
- UMA overhaul [DISCONTINUED]by Greenagon! If you want only specific things from this mod please download it and make your own smaller packs so I don't have to flood the workshop with them ! UMA overhaul is a ( work in progress ) graphical mod that changes a few sprites of the game. I personally like these custom textures more but due t...9.2k downloadsupdated 8 y ago
- better crowns [outdated]by 76561198876704734THIS MOD IS OUTDATED. GET THE 2.0 VERSION WITH BETTER SPRITES AND DARK PRINCE'S CROWN DIAMOND VISUALS BAKED IN HERE This mod makes crowns look like they're made of some kind of crystal or glass. If you want dark prince's crown to also make your tears into diamonds, you can download this mod: by M...9.1k downloadsupdated 5 y ago
- Fancy Coin Trinketsby EMORYFancier and more consistent sprites for all the different penny trinkets. Based on the coin designs from this mod:9.1k downloadsupdated 5 y ago
- Soupe's Portrait Pals: a Portrait Resprite Mod!by soupeREAD BEFORE DOWNLOADING! SOUPE'S PORTRAIT PALS! w/ Accurate Character Select and Tainted Names support! By default, this mod only changes the default portraits. If you'd like ACS & Tainted Names, check the mod file! There's instructions. This also applies to any modded character as this mod isn't...9.1k downloadsupdated 9 mo ago
- Neko Boom Flies (NOW WITH RED FLIES!)by 76561198842354630MAKES THE BOOM FLIES LITTLE KITTY CATS LITTLE GUYS LITTLE LITTLE GUYS CUTE LITTY KITTY CATS!!!!!!!!!!!!!!!!!!!!!!!!!!! UPDATED AND NOW INCLUDES CHAMPIONS + RED ONES9.1k downloadsupdated 4 y ago
- Accursed! (REPENTOGON EDITION)by BriesFlippersTHIS MOD REQUIRES REPENTOGON TO FUNCTION. This is an update to the original Accursed mod. The reason it's a seperate upload is to make sure players who won't, or can't use REPENTOGON can still enjoy the original mod. This update includes proper Curse of the Labyrinth functionality, an optional to...9.1k downloadsupdated 2 y ago
- Enemy Blood Donationsby 76561198330371330This mod gives a lot more use to your temperance cards, allowing blood donation machines to accept blood from all enemies and not just Isaac! Enemies that touch blood donation machines will donate their blood for coins taking 25 damage per use (+5 per floor). Additionally, bosses take 40 damage (...9.1k downloadsupdated 4 y ago
- Unique Music for Cameo Bossesby Clove G.This mod adds unique music for the cameo bosses that appear in other games Edmund McMillen made, using music from the games they originated from. Tracklist: Vs Boss: C.H.A.D. - C.H.A.D.'s Lullaby | Super Meat Boy Steven - Time F cuk SIHT | The Basement Collection Gish - Versus Music | Gish Sister...9.1k downloadsupdated 1 mo ago
- Jacob and Esau without collisionby FailkidThis mod simply removes the collision between Jacob and Esau while playing as them. This allows for them to be put on top of each other.9.0k downloadsupdated 3 y ago
- Za Warudo (Works on Rep!)by raineThe voiceover for "The World" has been replaced with your beloved Dio yelling "ZA WARUDO!" Now includes "ODURAW AZ!" (replacing The World?'s reverse voiceover) Update: Unless it's an easy fix, I will no longer be supporting this mod. However, given that it's an incredibly simple mod, the likeliho...9.0k downloadsupdated 5 y ago
- [Room Pack] 267 New Balanced Roomsby Cash CabDoes what it says on the tin! Increases variety by adding 267 new balanced vanilla style rooms to the game, including new rooms for the alt path. All rooms are normal type rooms (i.e. no treasure rooms, challenge rooms, boss rooms etc). Number of rooms by floor Chapter 1 Basement: 22 Cellar: 23 B...9.0k downloadsupdated 21 mo ago
- Ghost Pepper Rework!by Mr. HeadcrabThe beloved Ghost Pepper is looking hotter than ever! This all new Ghost Pepper shoots out the same white flame you can find in Downpour, one that will exorcise any monster in it's way! These disembodied souls are far weaker than the hosts they come from, and will prioritize getting back into the...9.0k downloadsupdated 3 y ago
- Fixed Music Speedby 76561198986837426Don't like how Stop Watch and other effects mess with the music? This mod fixes the music speed to its default, ensuring its pitch and speed never change.9.0k downloadsupdated 5 y ago
- Downpour Mirror is Reflectiveby catinsuranceRequires REPENTOGON. Will immediately break without it lol Makes the mirror in Downpour actually reflective. Essential modding.9.0k downloadsupdated 3 y ago
- the binding of maggy's toy box and WOB isaac's secret stashby 76561199032451894BUG FIX: 超级撒旦和鲍勃的烂头动画修复! MegaSatan and Bobsrottenhead Animation fix! 炸弹乞丐被炸不出炸弹修复! Fixed the Bomb Bum not dropping an insta-exploding bomb when blown up! 究极傲慢宝宝瞎几把乱闪修复! Fixed the Ultra Pride Baby incorrect flashing animation! 个人整合包,非原作者,模组来源: maggy's toy box maggy's toy box reborn WOB isaac's sec...8.9k downloadsupdated 12 d ago
- Start with Birthrightby BarjuhStart each run with Birthright Collection with all my Start with mods :8.9k downloadsupdated 3 y ago
- Christmas Themed Stuffby StewartismeHere is a Christmas Isaac mod that reskins various things to be christmas-y. More to be added but right now 6 bosses 16 enemies Forgottens Bone is now a candycane and it sparkles Moms knife is a sharpened candy cane 2 Familiars Scarfs for keeper/t.keeper Christmas lights are going up! Angels/Devi...8.9k downloadsupdated 23 mo ago
- Better Special Roomsby SoulsAdds 3 extra items to special rooms, two free items in the shop (as well as two golden poops and soul hearts), and every special room has at least 1 free item (including, but not limited to, devil rooms, curse rooms, secret rooms, sacrifice rooms, etc.) Isaac's room, chest room, dice rooms and th...8.9k downloadsupdated 8 y ago
- Challenges Have Treasure Rooms [REP]by ZERBI-XCVIIThis mod enables Treasure Rooms during Challenges. Notes: - this mod works only for "original" challenges (so not for challenges from mods). - this mod is not compatible with other mods that change the challenges.xml file; Afterbirth+ version:8.9k downloadsupdated 2 y ago
- PVZExplosion(re-upload)by 76561199478108306A re-upload of this amazing mod by xanxan Replaces Normal bombs, Giga bombs, and Mini bombs (From scatter bombs) Explosions and sound effects! Sprites from PVZ Ds - Thanks to Spriters resource SFX from PVZ - Thanks to PopCap (duh)8.9k downloadsupdated 10 mo ago
- Random Run Generatorby 4lgui/nA random run generator for the character selection menu in case you don´t know what route to play. This mod requires REPENTOGON What´s in the mod? - Chooses a random character between normal and tainteds - Chooses a random route (Beast, mother, lamb, etc.) - Chooses random extra challenges - Disc...8.9k downloadsupdated 15 mo ago
- Rock Bottom In Treasure Rooms (Broken, will not be updated)by FurbyAdds 1 copy of rock bottom to the treasure and greed treasure pools.8.9k downloadsupdated 6 y ago
- Epiphora Buffer Frames (Old)by 76561198855158338THIS IS THE OLD VERSION OF THIS MOD! Go download the new version! Video footage provided by Namie Kuningham! They also have a video detailing every item this mod affects here:8.8k downloadsupdated 4 y ago
- Start with Godheadby BarjuhStart each run with Godhead Collection with all my Start with mods :8.8k downloadsupdated 4 y ago
- (Ascent dialogue) Peter, what are you doing?by 76561199450244000replaces mom and dad fighting (cringe) with peter and brian arguing about crack (awesome)8.8k downloadsupdated 9 mo ago
- Set Max Scaleby StlkngneThis mod lets you set the MaxScale option from your options.ini file from within the game. MaxScale controls how zoomed in you are. The default of 99 works fine for normal rooms, but if you're in a larger room then you may want to set this to 1-4 to zoom out a bit. For some reason, 5-99 appear to...8.8k downloadsupdated 22 mo ago
- Cat Characters!by 76561198896638753holy shit cat characters This mod includes all characters, including tainted ones! (Does not include the boss images and main menu portraits) THIS MOD IS NOT GETTING UPDATED SORRY !!!8.8k downloadsupdated 4 y ago
1.6k tweaks mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

