The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth tweaks mods
Everything filed under tweaks by its own author, ordered by how much it is used.
1,627 tweaks mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
1.6k tweaks mods
- Trinket Outlinesby O_oAdded outlines to trinkets that didn't have any, namely: Error (404) NO! Karma Daemon's Tail4.4k downloadsupdated 9 y ago
- Fallen Gabriel spawn a imp instead of a angelic babyby Guilhermedon't make any sense fallen gabriel spawn angelic baby, so, this mod makes fallen gabriel spawn a imp instead of a angelic baby4.4k downloadsupdated 6 y ago
- Boomerang but its Gabriel from Ultrakillby 76561198390663903Ever hated the boomerang and thought: "Man I wish it was Gabriel, not his spinning swords, but like actually him." Well then this mod is for you! Using some scuffed coding and MANY voicelines, you can throw your own gabriel at enemies and/or pickups!4.4k downloadsupdated 4 y ago
- Obvious Tinted Rocks - Fiend Folio: Reheatedby KolateakObvious tinted rocks for Fiend Folio: Reheated4.4k downloadsupdated 4 y ago
- Yuji_Itadoriby 76561198891024058This mod adds a new character Yuji Itadori -Yuji Starts whit spirit sword and meat cleaver -Spirit Sword model changed to Slaughter Demon Plans for this mod: Add sukuna (tarnished version) Make the Slaughter Demon a Standalone item I hope you'll enjoy the mod Its the first mod i ever made4.4k downloadsupdated 14 mo ago
- True Co-op Boss Resurrectby 76561198443397846An add-on for the True Co-op mod which resurrects all dead players at the end of each boss fight, at the cost of losing the reward item.4.4k downloadsupdated 7 y ago
- alt. Plan C sprite!by ViscerARedesigned sprite for Plan C. Now it's not just Forget Me Now with a red tint :) Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading every sprite tweak separately...4.4k downloadsupdated 6 y ago
- Start with Damoclesby BarjuhStart each run with Damocles Collection with all my Start with mods :4.4k downloadsupdated 3 y ago
- Daemon's Tail "Fix"by Khakis"Fun" fact: Daemon's Tail has a 80% chance to prevent Soul Hearts from Blue Fire Places and Tinted Rocks from spawning, but does not change them to Black Hearts because it only affects "random" Heart drops (like from room clear rewards & Chests). Does that sound lame to you? Well this mod kinda f...4.4k downloadsupdated 3 y ago
- Start with Technologyby BarjuhStart each run with Technology Collection with all my Start with mods :4.4k downloadsupdated 3 y ago
- Maggy's Redemptionby 76561198876704734Funnyman Modding Enterprises presents a commission for Sulfur Male: Maggy's Redemption! This mod gives Maggy, a usually quite boring character, a damage up and a slight tears down to start with, as well as a completely new mechanic: Every time she steps on self sacrifice spikes after having taken...4.4k downloadsupdated 4 y ago
- Antibirth Room Packby fly_6WARNING! Currently the game is poorly friendly with custom rooms, and it is possible that after leaving the run and its continuation can cause the game to crash (because what logs says, rooms vanish for some reason :v) This mod brings back (almost) all the rooms from Antibirth mod to Repentance (...4.4k downloadsupdated 5 y ago
- [REP] Lifebar - HUD Reskin mod (and more!)by peasPrettify your HUD! This mod reskins various HUD elements to look more visually appealing, taking inspiration from the flash game's unique art style. This mod also reskins select pickups and consumables when dropped on the floor, and whatever else I felt like remaking at the time. Expect updates w...4.4k downloadsupdated 5 y ago
- [REUPLOAD] Aladar's UI Hearts Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...4.4k downloadsupdated 17 mo ago
- [REP+] Remove useless heartsby 76561199164471930Useless hearts will be replaced by soul hearts Blue Baby, Tainted Blue Baby, Tainted Judas and Tainted Forgotten no longer generate red hearts. The Lost and Tainted Lost will replace hearts with coins. Compatible with co-op, characters have priority in converting hearts to make it playable. One c...4.4k downloadsupdated 9 mo ago
- GoldenKeeperby 76561199091925974Changes everything below - Keeper and Tainted Keeper - Greed and Ultra greed (they share sprites with the characters) - Most of Keeper's costumes - Animations for the Greeds and Keepers - Wooden nickel - Eye of greed - Crooked Penny - Strawman - Keeper's sack - Keeper's kin Any mod that changes t...4.3k downloadsupdated 2 y ago
- Sin Iconsby The SwagmobileThis mod adds a custom skull icon for all the sins and super sins. This mod is not compatible with Enhanced Boss Bars. Please let me know if you encounter any bugs!4.3k downloadsupdated 3 y ago
- Start with Red keyby BarjuhStart each run with Red key Collection with all my Start with mods :4.3k downloadsupdated 4 y ago
- Unique Tainted Edenby ViscerANow Tainted Eden has a unique appearance! Includes: New sprite for tainted Eden (compatible with all skin colors), new stage portrait (and planned custom costume support, but I will need someone to help me figure out the lua I'd need to accomplish this) Warning: This mod may not be compatible wit...4.3k downloadsupdated 5 y ago
- Improved Monster Manualby 76561198330371330Funnyman Modding Enterprises is eager to present its newest project, commissioned by MrTea: Improved Monster Manual! This mod features a full, ground-up rework of the item, spawning a unique, permanent familiar based on what room you first activated it in, which you can upgrade with later uses! A...4.3k downloadsupdated 4 y ago
- Item Pickup Soundsby PoondaedalinHowdy! This mod allows the game to play a myriad of custom silly sounds when picking up some items, and the sounds will be either positive or negative based on the item quality. --------------------------- For the record, here's the full list of sounds that can be played: - Positive (Quality 4) M...4.3k downloadsupdated 3 y ago
- Tweaked Nancy Bombs spriteby ViscerATweaked sprite for Enigm- I mean, Nancy Bombs. Now it's rainbow, to accentuate the item's effect's randomness, and also, because rainbows are fucking awesome. They are just sooo pretty. I love them. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite...4.3k downloadsupdated 5 y ago
- Curse of the Fullclearby (SHG)TLgamingThis is my first lua mod. The name says it all. It is the Curse of the Fullclear. You have to Fullclear the floor before you can leave. As reward you can enter every room for free and you have to. We need to go deeper is the only workaround. If you experience any bugs please let me know. Have fun...4.3k downloadsupdated 3 y ago
- [REUPLOAD] Nioffe's Backgrounds and Doorsby 76561198408359456So yeah if anyone isnt in the loop Nioffe the original mod creator deleted his account and everything on it goes *poof*. I figured this stuff is still all very useful to some ppl and stuff so here's the mod reuploaded which includes both his backgrounds and doors. A real shame you had to go Nioff...4.3k downloadsupdated 4 y ago
- Boss Resprite - The Gateby FerpeRe-resprited and re-reanimated a boss people often forget about, The Gate. Complete with its championa nd Delirium variants! This time it's a completely unique design, since I didn't like how my older resprite looked. If you still prefer the older version it's still available here: This resprite...4.3k downloadsupdated 3 y ago
- Nioffe's Doors Revelations Compatibilityby 76561198408359456Following in the spirit of Nioffe who made compatibility between his mod and others I have decided to also create some custom sprites for the boss, angel, and devil doors for the Revelations mod. All the other doors in the mod are fine as is, its just these three that looked off, especially the b...4.3k downloadsupdated 4 y ago
- More Jingles! (OUTDATED)by SoundbinPlease download More Jingles! Repentogon instead4.3k downloadsupdated 2 y ago
- Library Fixby krameraadThe left and right walls inside the library look a little weird. This mod fixes that. It also introduces a little bit of randomness in the books and pages on the ground, so they don't always appear and are distributed a bit less symmetrically.4.3k downloadsupdated 5 y ago
- [REP] Incubus Unnerfby MiyukkiWith this mod Incubus again gives player's damage instead of 75%, same as before Repentance You can get this modification in my Repentane Unnerf Pack too4.3k downloadsupdated 5 y ago
- Standardized Item Weightsby joshChanges every item's weight to 1. Works for REP and REP+ 1.9.7.17 ========================================================================= Note: This will affect some of Tainted Cain's recipes. When playing as him, disable this mod if you're looking up or have memorized some of his recipes. This...4.3k downloadsupdated 3 mo ago
- Mines Rewardby KojimkjDo you find Mines/Ashpit too risky for too little reward? You can now add slightly more reward to those floors! Changes While in Mines/Ashpit, special rock types have an increased chance of replacing regular rocks Additionally, you may now encounter a gold version of the Hardy enemy in Mines, whi...4.3k downloadsupdated 10 mo ago
- Caves n' Creatures!by Mr. SeemsGoodNOTICE This mod is a little unorthodox in the sense that it's very easy and prone to getting you stuck inside the minigame, one way or another. We also aren't the best coders. Should you ever find yourself in this situation, you should be able to exit and continue your run, in which you'll be sen...4.3k downloadsupdated 3 y ago
- The Forgotten is now "Boner"by Scary-JelloMy friend wanted me to remake an afterbirth plus mod that just changed the forgotten's name to "boner", so I did, took like 30 minutes. This mod probs doesnt work with other mods that change the character select screen, boohoo.4.3k downloadsupdated 4 y ago
- D666by micromarioDescription: Reroll your soul Itempools: Treasure and devil Effects: (Active) If you have red health, the item takes two hearts away and gives you a random devil deal item If you have soul health, the item takes three hearts away and gives you a random devil deal item If you don't have health, th...4.3k downloadsupdated 10 y ago
- [REP] 20/20 Unnerfby MiyukkiRemoves 0.75 damage multiiplier from 20/20, with this mod it works again like before Repentace You can get this modification in my Repentane Unnerf Pack too4.3k downloadsupdated 5 y ago
- Random Remaining Completion (Updated!)by Hex: Consume SoyREQUIRES REPENTOGON MOD CONFIG MENU IS RECOMMENDED Updated! Now works with modded characters, both classic and tainted. Not functional with certain mods (e.g. Epiphany), but will not break anything. Currently on save file 2, I’m plagued by trying to decide who to play, as the vanilla random selec...4.3k downloadsupdated 2 mo ago
- He's a Phantom [SFX]by machasinsThis mod simply plays a part of the Danny Phantom Theme, "He's a Phantom", whenever Isaac becomes a ghost in Downpour/Dross. Issues? Report it here or in the comments of this mod. Can be configured with Mod Config Menu to adjust how loud the sound is. Thanks to Lazy Mattman for inspiration. I use...4.2k downloadsupdated 16 mo ago
- MajorasMaskModby GiurassicEver wanted to feel protected ? Ever wanted to feel powerful ? Well now you can ! The ALL NEW Majoras Mask will give you everything you need (if all you need is a +5 damage up and 2 black hearts) Soon to come : Different tears ANIMATIONS MORE items Suggestions are welcomed :D4.2k downloadsupdated 10 y ago
- Start with Knife piece 1by BarjuhStart each run with Knife piece 1 Collection with all my Start with mods :4.2k downloadsupdated 3 y ago
- Early Greed Donation Machineby NachitoPlaces a Greed Donation Machine right before the Ultra Greed/Greedier boss fight.4.2k downloadsupdated 3 y ago
- No Stickies on Tainted Keeperby DoggersI think Tainted Keeper players can relate to this scenario. You are playing Greedier mode. You are left with a single coin heart, because game has decided to give you a bullet hell. You have killed a little poor Gaper which has dropped a Nickel! Time to pick it up. Wait, what's that? It's glued t...4.2k downloadsupdated 3 y ago
- Sir Dumpertonby [Larimarr]A snazzy wardrobe upgrade for everyone's favourite puffy lil guy!4.2k downloadsupdated 2 y ago
- Psy Fly & Baby Plum Titlescreenby CheatFreakPsy Fly and Baby Plum now greet you on the titlescreeen instead of that boring old black fly. Now includes an alternate version where Plum is 50% larger. To use the alternate one rename the current fly.anm2 to something else, then rename fly.biggerplum.anm2 to fly.anm2 Combines two mods I made No...4.2k downloadsupdated 5 y ago
- Bee Girlby lesserStarreplaces lord of the flies with a cute lil bee girl! black outline alt available in the mod folder (manual file replacement required)4.2k downloadsupdated 2 y ago
- Beth The Demon: Remasteredby Anya MouthwashingAn Original character, Beth! She's a Brimstone demon who loves matchmaking! Using her charming MATCHMAKING BEAM, she can obliterate enemies, make them fall in love, or both! (No relation to the Repentance character, Bethany.) Beth has been REMASTERED, now featuring beautiful art and sprites by So...4.2k downloadsupdated 5 y ago
- Monstrance Respriteby BaicherraThis mod change the "Monstrance" item sprite.4.2k downloadsupdated 5 y ago
- Discord Advance Rich Presenceby nikosBetter rich presence status. Important Currently there is only windows support. For this mod to work you need to enable the debug flag (instructions below). This is needed because in order to communicate with discord I need to write to a special file and to do that I need the debug flag on. The f...4.2k downloadsupdated 6 y ago
- Items Reforged [Afterbirth+]by KaliItems Reforged! This mod aims to rebalance and tweak items that would otherwise be detrimental to a run, while remaining faithful to the vanilla experience. Supports External Item Descriptions! Supports Mod Config Menu! Supports Revelations! Supports Fiend Folio! & More! All changes are configura...4.2k downloadsupdated 6 y ago
1.6k tweaks mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

