The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth active items mods
Everything filed under active items by its own author, ordered by how much it is used.
621 active items mods, most downloaded first · newest update 29 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
621 active items mods
- Virtue Itemsby 76561199121244854This mod adds 7 new items, each based off a heavenly virtue: Chastity, Temperance, Charity, Diligence, Kindness, Patience and Humility. It also adds a new transformation for those items: Saint. For more details, watch the YouTube video on the mod page, or go to IsaacGuru Requires REPENTOGON13.4k downloadsupdated 2 y ago
- [RGON]Benighted Soulby 76561198366643385!!!ATTENTION!!! REP+ is unrecommended, it may cause unknown issues REPENTOGON is necessary - What's in it? · 11+1 characters with complete unlock-trees! · 200+ items! · 3 transformations! · 6+1 bosses! · 11 challenges! · 2 curses! · More rooms! · More poops! · More bugs! - What's in the future? ·...13.4k downloadsupdated 17 d ago
- Better Clicker!by im_temThis mod reworks the Clicker item. Now you can choose the character you want to turn into! But be careful with who you choose since Clicker is now one time use item!13.3k downloadsupdated 6 y ago
- Every Item Is Xby calvinhobbes1010You ever wanted to challenge yourself with a run where every item you take is only one kind of item (such as Soy Milk)? Do you love (/s) bringing up the debug menu a lot? Do you find yourself in an eternal state of tedium where challenges like this are your only source of joy in life? Well, this...13.3k downloadsupdated 8 y ago
- Isaac's Keyboardby anchikaiThis mod will no longer receive updates. Play Furtherance instead! Is R Key not enough for you, and you wish you could press all the various keys with an active item instead? Introducing, Isaac's Keyboard! This mod introduces 11 brand new keys to the game that all spawn in the secret room: Esc Ke...13.2k downloadsupdated 5 y ago
- Start Item Optionsby ۩۞۩ FerMod ۩۞۩This mod adds four initial items options to choose from in the starting room. These items are spawned from the treasure room item pool. Because of this, the treasure room of the first level is always empty. Although, when the level has the 'Curse Of Labyrinth', the second entered treasure room wi...13.2k downloadsupdated 4 y ago
- Devoid: Apollyon Reworkby 76561198412573006Devoid This Apollyon rework centralises around making the character more fun to play by introducing a new gimmick to the character, and changing the void active item to both be less complicated usage whilst also tying in with the new gimmick. Locust Portals Apollyon now starts with an innate abil...13.2k downloadsupdated 3 y ago
- Pudding And Wakaba [REP/RGON/WIP]by 리셰The various uncommon girls arrived to basement! REPENTOGON/REPENTANCE ONLY! Does not work with Afterbirth+! Requires External Item Descriptions(English/Korean/Chinese(wip)) Mod Includes : 11 Characters 80+ Items 15+ Trinkets 15+ Card/Runes 10+ Pills 20 Challenges Items Under construction, Using E...13.1k downloadsupdated 11 mo ago
- Duke (2 New Characters + 20 Unlocks!!)by ryonTHIS MOD IS NO LONGER MAINTAINED. Some parts might still work, but at this point it is probably pretty broken. We will not be pushing any more updates or fixing any more bugs. Sorry! Do you like flies? Do you wish that your heart was replaced with flies? Maybe the rest of your internal organs too...13.0k downloadsupdated 4 y ago
- Auri Eid 汉化by 76561198423610277Auri的汉化mod 目前只实现了EID汉化 mod无效请先检查一下mod列表,eid、Auri、AuriEidChinese是否加载并启用了 忏悔+版本,请检查edi本体语言设置是否改为了中文(默认英文) 各角色解锁方式(可能已过时) Auri: 使用以撒获得"满分答卷"(A+) Dark Auri: Auri获得全部困难模式的通关标记 Witch of endor: 在一局游戏里获得3个幸运币 HANG GIRL:使用AURI死于非自伤4次。@Mingmen 提供的测试 Milcah: 使用Auri通关游戏,并受到敌人超过19次的伤害。 不完全看懂, 感觉是这么个意思, 原文: Un...13.0k downloadsupdated 4 mo ago
- Blinksby ScayzeBlank bombs ain't your thing? How about Blinks! Blinks are an active item you can find in shops that open secret room doors, and clear the screen of bullets whenever you want! Neat! However, you get 3 charges per floor that cannot be replenished at all until you go down to the next floor, where y...13.0k downloadsupdated 10 y ago
- The Mirrorsby ☢ Nato Potato ☢This mod adds 5 different mirrors to the game, 3 passive items, 1 active item and 1 trinket, the Portrait Mirror, the Landscape Mirror, the Cursed Mirror, the Hydrophobic Mirror and the Item Mirror. The Portrait and Landscape mirrors add a 'reflection' of Isaac into the game as a familiar/friend,...13.0k downloadsupdated 22 mo ago
- OMORI (Character Mod)by 76561198813796283THIS MOD REQUIRES REPENTOGON TO WORK “Wow, it really is you. It’s been a while, but you haven’t changed a bit.” ------------------------------------------------------------------------------------------- Everything's better with friends; even the exploration of hellish, metaphorically-rich dreams...12.9k downloadsupdated 10 mo ago
- Furtheranceby BennyA complete overhaul of the The old Furtherance MOD originally released in 2022. Coded from the ground up under the experienced eye of a single coder with the power of REPENTOGON, this new release breathes new life into every corner of the original MOD to create a sizeable quality package of conte...12.7k downloadsupdated 15 mo ago
- the binding of Cirnoby 御坂14144号Cirno, The smartest & strongest girl. At least she believes in that xd. This MOD includes a NEW character Cirno (Nihiri version) And her private treasure Ice Frog (not the one who is making DotA) Cirno starts with 3 soul hearts; Uranus;(冻符「Perfect Freeze」) The Inner Eye & The Wiz; (冰符「Icicle Fall...12.7k downloadsupdated 3 y ago
- PLAYABLE MACHINES!by 76561198848623108𝗧𝗵𝗲 𝗲𝗿𝗮 𝗼𝗳 𝗺𝗮𝗰𝗵𝗶𝗻𝗲𝘀 𝗵𝗮𝘀 𝗰𝗼𝗺𝗲, 𝗜𝗧'𝗦 𝗚𝗔𝗠𝗕𝗟𝗜𝗡𝗚 𝗧𝗜𝗠𝗘! 💵💵💵 !! This mod requires REPENTOGON !! The Gambler Play as the Gambler, the most ludopatic machine ever. Pick up coins to have a chance to spawn one of these possible rewards: • Coins (These will be added directly to your coin counter) • A random...12.7k downloadsupdated 4 mo ago
- Black Holeby Custom PhaseIMPORTANT UPDATE: THE ITEM IS OFICIALLY IN THE GAME NOW, YOU DONT NEED TO SUBSCRIBE TO THIS MOD ANYMORE. Thanks for the support and kind words everybody! Screenshots/video are outdated, the item has been significantly nerfed with the latest updates. Black Hole is a throwable active item similair...12.6k downloadsupdated 10 y ago
- IM FUCKING INVICIBLEby GodWladiFeel the power of invincibility like never before with this custom mod! Sundowner from Metal Gear Rising: Revengeance will support your with his sexy voice. When you activate invincibility items like Book of Shadows, My Little Unicorn, or the Algiz Rune, you'll be immersed in intense sound effect...12.5k downloadsupdated 4 mo ago
- Pocket Actives+ [Coop | Config | Clicker | Revives | Mods]by AgentCuccoNon-Tainteds now start with Pocket Actives! This mod will give every A-Side character their Active Item as a Pocket Active, and it even comes with config options. Features: - A-Side characters start with Pocket Actives. ---- Full Coop support. ---- Revive support. ---- Clicker Support. ---- Modde...12.5k downloadsupdated 6 y ago
- Portal of Friendsby NickSquigglesNOTE: This mod is currently not supported in Repentance. Instead, use 'Lil Friend Portal' mod here: ---------------------------------------- Fight off the masses of portals with your own! Portal of Friends is an active item that creates a friendly portal which spawns friendly, charmed enemies. Al...12.4k downloadsupdated 10 y ago
- More Minisaacsby Iris HeartThis mod is inspired by Unique Minisaacs mod: I love the variety of minisaacs that mod brings, so I wanted to see results of that mod more often, and that's why I made this mod. This mods adds a new heart type: Cell Heart. Red Hearts have a 10% chance to be replaced with Cell Hearts. Cell Hearts...12.4k downloadsupdated 5 y ago
- Sacred Diceby MorcEver wanted an item that combines the Sacred Orb and Eternal D6 - and all that in the shape of a new dice?? No? Well we made it anyway! This brand new quality 4 active item lets you re-roll items into a random item of +1 quality higher than before! But it comes at a cost.. - There is a 60% chance...12.4k downloadsupdated 2 y ago
- Eternal Character Itemsby catinsuranceEternal Character Items A mod that allows you to set if a character's starting active item is put into their pocket active slot, and if any trinkets they're holding will be put into their permanent inventory (gulped). Features: Works in Repentance and Repentance+. Customize which characters will...12.3k downloadsupdated 13 mo ago
- Risk of Rain 2 Items and Chests [REP - SURVIVOR UPDATE WIP]by CaMpeRThis mod adds 50+ Risk of Rain 2 items which are stackable with themselves to increase the effectiveness of the items! These items will only spawn via the Risk of Rain item chests which only spawn at the start of the floor (or with special conditions). These chests will not replace any of the van...12.3k downloadsupdated 4 y ago
- Only Modded Itemsby HiHowAreYouThis mod will only work if you have other item mods installed! This mod removes all items from the base game, with the exception of items dropped by bosses. This is to ensure you get the stat ups needed to progress. I recommend you browse the workshop for cool items! There are a lot!12.2k downloadsupdated 6 y ago
- Foks' Booster Packby FoksRequires to work! The mod aims to add simple vanilla-like stuff into the game, currently adds: - 48 new items! - 19 new trinkets! - 2 new cards! - 1 new pickup! Check out the Isaac Guru page for more info! These mods are supported: - External Item Descriptions - Accurate Blurbs - Hush's Item Pool...12.2k downloadsupdated 12 mo ago
- Portal Gunby ☢ Nato Potato ☢The Portal Gun is an active item which when used shoots out a portal, you can use the item twice in a row and create 2 portals that will teleport yourself and most entities that enter it. The portals form on whatever solid object you are aiming at when you use the item, portals can spawn on walls...12.0k downloadsupdated 4 y ago
- StrawPack 2by MozzieAdds 6 items, 5 trinkets and 1 challenge to the game! Art and thumbnail by Aczom. Code by Strawrat. This mod uses a cropped version of the following sound effect from Freesound: "01543 flying dragon" by Robinhood76. NOTE: If you already have any of these items individually installed, be sure to d...12.0k downloadsupdated 9 y ago
- Vazkii's Item Packby VazkiiThis mod adds a few new funky items to the game: - Eye of the Subconscious: Isaac stops being able to fire manually and will fire like Demon Baby. (Devil Deal Pool) - Remote Control: Bombs move in the direction of Isaac's tears. (Shop Pool) - Bleeding Edge Tech: Technology that is aimed towards I...11.9k downloadsupdated 10 y ago
- delirium drops r keyby gan_regenas per a request on reddit. for those of you who wanna get completion marks easier but in a more spicy way. 💖 (pretty much just an alternative to the every floor mod.) definitely works in repentance, should work in ab+, dunno why it wouldnt. edit: r key isnt in ab+ to begin with oh my god lol11.9k downloadsupdated 5 y ago
- Static Bag of Craftingby IxionThis mod makes BoC use a static seed for item generation, meaning that all recipes will always be identical between runs. This (mostly) restores the old behavior of Tainted Cain before Repentance v.1.7.5. Extended Item Descriptions mod is supported, but you need to be holding the bag above your h...11.9k downloadsupdated 4 y ago
- Sprinklerby KieranSprinkler is an active item which is able to be put down in a room. It rotates in a circle spraying tears in each direction, and synergises with the player's tear effects. It also currently works with Mom's Eye, Loki's Horns, Tech X, Dr. Fetus and Brimstone, and includes custom models for certain...11.9k downloadsupdated 10 y ago
- The Binding of Steve (Rep. version) : Minecraft Crossoverby Ly FechaIf you like my work, please consider clicking on the like, favorite or even reward button. THIS IS THE REPENTANCE VERSION. Afterbirth+ version : Warning : Due to game and api instability, sounds and some items have been removed temporarly. They will probably be added back after some Repentance up...11.8k downloadsupdated 4 y ago
- [AB+ TESTED ONLY] Cannibals!by HiHowAreYouNOTE: I have not updated any of my mods to Repentance. I'm not sure if I will or not. If I do, it'll be after I've explored the update enough, I don't want to get spoiled by testing mods. They consume each other! This mod adds two items, one passive, and one active. Scratch Scratch is a one room...11.8k downloadsupdated 8 y ago
- Time Reducerby ElRichMCActive item that reduces your run time.11.6k downloadsupdated 10 y ago
- Brown Shapiro's Addons - New Items and Trinketsby Billie IrishNote: Sometimes the mod breaks, making the game freeze upon starting a run. This seems to be because of the savedata files in /data/brown shapiro's addons, which might clog up. Deleting them should make the game work again, if that happens. --- This mod currently adds 37 items and 13 trinkets int...11.5k downloadsupdated 4 y ago
- Item ban listby ☢ Nato Potato ☢Are there items you just hate getting? This mod lets you remove any items you don't want to appear, allowing you to have a customised list of items that are not allowed to spawn or be held by the player, replacing them with a random item or a specific item of your choice. The mod also forces acti...11.5k downloadsupdated 11 mo ago
- Alice of Blue Archiveby 76561198448106326Added a new character "Alice" and her tainted version. Alice: Can fire hight speed Bullets With a little time charge. Each times fire Bullets will add active charge to pocket active item "Swold of Light". Use Swold of Light will shoot a big Shell with a huge Damage. when charge of Swold of Light...11.4k downloadsupdated 3 y ago
- Cracked Batteryby MerloMany people on reddit have amazing ideas, but can't code them. I, on the other hand have zero ideas, but could code them all. Enter the Reddit's Community Mods Project, where I'll go and find the best ideas from the community, and bring them to life! Check out the full Community Mods Collection o...11.3k downloadsupdated 9 y ago
- Character Changerby ☢ Nato Potato ☢Accidentally picked the wrong character and don't want to lose your win streak? Started an Eden run and didn't like the items? This simple little tool lets you change characters during the middle of a run without having to restart. Just open the Mod Config Menu and go to 'Change Character'. You c...11.3k downloadsupdated 4 y ago
- ModJam Vol. 2 (14+ New Characters!)by 76561199208948209REPENTOGON+ IS REQUIRED! You know the drill, download Repentogon+ here! ModJam Vol. 2 focuses on CHARACTERS, rather than items! We present a whopping 14(?) characters, 7 normal characters and 7 tainted characters. Each team had to make a normal character over the span a few weeks, and then was gi...11.2k downloadsupdated 2 mo ago
- Angel Drop Items Remakeby RudyA remake of the original Angel Drop Items mod, with new features, bug fixes, rebalance and support in the current game version. Were you ever annoyed that after getting both key pieces fighting both Uriel and Gabriel was entirely pointless? Have you never gotten lucky to get the Filigree Feather...11.1k downloadsupdated 10 d ago
- salvationby XtrikeThe Binding of Isaac: Salvation Salvation or Repented characters is a mod that aims to be an alternative of the tainted characters but instead of getting more broken they become more innocent. So far we have 1/17 Characters Completed, being Azazel For each character there is atleast 9 unlocks as...11.1k downloadsupdated 2 y ago
- Mama Mega Yoby MattyMy name is Mama Mega, yo. Changes the Mama Mega/Golden Mama Mega sprites & HUDs, as well as the explosion sound. SFX Credit goes to Vine Boom Bombs II11.1k downloadsupdated 23 mo ago
- Mechanical Eyeby NiroMechanical Eye Upon use, Isaac throws an eye. When the eye sticks to a wall or a rock, it starts to shoot tears in a straight line like a turret. The tears are affected by your Damage, Tear Delay, Range, Shot Speed, and Tear Effects. Huge amount of synergies: Car Battery (throws 2 eyes) Mom's Kni...11.0k downloadsupdated 4 y ago
- GuppyWaifuby Mr_RomanThis mod adds a Guppy Waifu. Yep, this mod exists, live with it. Everything I wanted to do, I did. And what this mod adds: - Redrawing Guppy's items - Redrawing Guppy's transformation Special thanks to the authors from whom i borrowed sprites for mod: MrGromsn_ (mod GuppyGirl) Minygold and Skelet...11.0k downloadsupdated 4 y ago
- Isaac with Meowmere!!!by 76561198427553819My first retexture ever! Had fun listening to the sound of meowing. It has synergy retextures as well! Also includes a fun little silly on Tainted Azazel. :) Thanks to @Namie Kuningham for showcasing the mod! Retexture only: Pastel Brimstone:10.9k downloadsupdated 4 y ago
- Combo Onion Ninjaby SinstharCombo Onion Ninja is an active item with 6 charges... BUT you can use it even if you only have 1 charge ! However, it does nothing if you only press your item button ; you must perform a combination (with the direction keys) to unleash its powerful attacks ! Onion Slice (easy, 1 charge) : - Press...10.9k downloadsupdated 10 y ago
621 active items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

