Mods / Active Items

• RRooms and Roams (700+ rooms)by MarbleTearsHello, welcome to Rooms & Roams!! an expansive mod for more adventures This mod add Adds: 100+ rooms for every chapter (basement, caves and depths) 50 + rooms for every alts (burning basement, cellar, etc) 50 + rooms for every alt2 chapter (downpour, mines, etc) + 200 special rooms (planetariums,...8.9k downloadsupdated 14 mo ago
• CCat-astrophe [Catgirl with gambling addiction - Awesome edition]by 76561199090151127What a catastrophe of a mod - Me ------------------------------------- Content 2 Character 19 Items 12 Trinkets 15 Pickups 3 Challenges and more :) ------------------------------------- Compatible EID (has spanish and ingles) Encyclopedia Fiend Folio Retribution Epiphany Library expanded Repentan...8.9k downloadsupdated 2 mo ago
• MMinecraft Tainted Cainby Modern Strange CowboyTainted Cain but Minecraft style. I spend waaaaaay to much time redrawing every single costume to fit his block head Also changes the bag of crafting into a crafting table, enjoy8.8k downloadsupdated 5 y ago
• GGuwah Greaturesby GuwahavelThis mod is for Repentance Have you ever felt a desire for something more to your floors? More intrigue? More greatures? More challenge? Then this mod is for you! This mod adds: -17 new enemies to test your mettle! -Over 1500 new rooms, spread across every floor in the game! -2 new items! -Surpri...8.7k downloadsupdated 4 y ago
• WWhite Candleby Tim l'enchanteurAdds an active item to the treasure room and angel pools : the White Candle. When you hold the candle, you leave a trail behind you. When you activate the candle, the trail is set on fire and deals damage to enemies that scales with yours. Flames synergize with the following status effects : pois...8.7k downloadsupdated 10 y ago
• RRepentance Negative-by 76561199094088506We present to you a mod that is not of the best quality, but with interesting jokes! Also, dig through the mod files, you never know what might be hiding there... Repentogon required! Adds 2 new character! Adds 30+ new items! Adds 5+ new trinkets Adds 1 new card, pill and new pickups and machine...8.7k downloadsupdated 8 mo ago
• BBalanced Starter Choicesby 76561199114159195Tired of walking into your very first Treasure Room and getting stuck with a single random item? Balanced Starter Choices replaces the lone starting pedestal with a configurable set of item choices, just like the "There's Options" pickups — pick one, and the rest vanish. WHAT IT DOES - On your fi...8.6k downloadsupdated 3 mo ago
• TThe Cursed and Brokenhearted - "I Never Forgot You"by 76561198813288416Notice I will not update this any further, I just readded it so people can play it Prerequisites for the best experience StageAPI - For the new bosses and such MMC - For the new music in the game! MinimapAPI Immortal Hearts from Team Compliance - For easier new personality unlock! EID - descripti...8.6k downloadsupdated 3 y ago
• GGood Dealsby 76561198865227624Will improve deals with the devil and angel, increasing the chances of getting the highest quality items 3, 4 and Guppy-related. Also changes predictions in fortune tellers. Thanks for translations and ideas Gusa and NixSaji The code for predictions was taken from the mod Antibirth Fortunes Updat...8.6k downloadsupdated 4 y ago
• CCereal Cutoutby nick***This mod was added to the game, and is now redundant. Thank you everyone for your support.*** CEREAL CUTOUT Allow 6 weeks for delivery Type: Active Cooldown: 4 Effect: Makes a random item in the shop free. Pools: Treasure, Shop, Beggar Cereal Cutout is an active item that makes a random item i...8.5k downloadsupdated 10 y ago
• DDark Razorby ☢ Nato Potato ☢The Dark Razor is an Active item which when used removes 1 heart container (or 1 bone heart or 1.5 soul/black hearts), gives you a black heart and triggers the black heart damage effect, hurting everything in the room. Aside from damaging rooms of enemies it can be used to convert empty heart con...8.5k downloadsupdated 2 y ago
• [[REUPLOAD] Aladar's Mushroom Items Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...8.4k downloadsupdated 17 mo ago
• LLocust APIby im_temThis is an API for adding custom effects to locusts. You can use it to get mind boggling effects! This mod does NOT provide anything on its own but I have released effect pack for this API (Locust Pack). Have fun!8.4k downloadsupdated 5 y ago
• DDataminer Descriptions CNby 76561198811272757为数据破解生成的错误道具显示中文效果描述，基于 EID 中文数据库优化显示。8.4k downloadsupdated 4 mo ago
• IInfini-Chest!by Dracula joeThis mod adds an item and a trinket, the Infini-Chest and the Incomprehensible Key! The Infini-Chest (treasure room pool, shop pool (0.5 weight)) is a 4 room charge active item that spawns a special locked chest named the Infinichest and consumes 1 key. Infinichests spawn 5 pickups OR an item fro...8.4k downloadsupdated 4 y ago
• BBeckyMod [Tainted Update]by 76561198992641386Play as Becky and Her Ghost Friend, Characters originally made after an Art Challenge Becky: You cannot shoot tears, your only attack method is a really bouncy ghost friend Devil and Angel Deals are swapped too Tainted Becky: Use Many different Spells, randomized each Run Acquire more through Dev...8.4k downloadsupdated 2 mo ago
• FFaith's Rewardby DaGammlaDo you have a bad Computer? Do the fireworks produce lag? Just press "F1" and you're save! CAUTION ! This mod is possibly not compatible with others but Works perfectly with True Co-op Content : --Dynamic Boss drops-- Bosses have a chance to spawn Boss specific items like Mask of Infamy -> Isaac'...8.3k downloadsupdated 8 y ago
• OOhyo - Character & +15 New Items [AB+]by AgentCuccoA brand new and unique character! Use your Blood Gauge to store red hearts and use them as charges, as well as becoming a sharpshooter to land critical hits on enemies. Use over 15 brand new items to help you traverse the basement! THIS MOD IS UNTESTED IN REPENTANCE Features: - A brand new and un...8.3k downloadsupdated 6 y ago
• EE-42: The Automaton [REP]by palookaE-42 is finally in her own standalone mod! Check out the original mod here: New Character! E-42 is a close-range, high-DPS character with a penchant for gargantuan bursts of explosive damage. She comes with +500 custom costumes and a menagerie of unique synergies; Using the Old Wardrobe or Old Wa...8.3k downloadsupdated 3 y ago
• DDusty Box of Friendsby ErflyAn old friend. Functions just like the pre-nerf Box of Friends, but doesn't replace the regular Box of Friends. This means that it takes two charges rather than four to use! Lilith will not start with this item. This item can be found only in secret rooms.8.2k downloadsupdated 10 y ago
• 警警长中文eid图鉴/z_Sheriff_EID_Chineseby YouDuckBoom8.2k downloadsupdated 2 y ago
• MMurasama (alpha)by 76561198802955004Start blood-ment with new weapon - Murasama Split monsters wide open! Actually a working mod 0_0 Alpha testing: resprite of spirit sword (Isaac's awakening is OP), resprite Tainted Samson to Jetstream Sam (Donkey Jaw resprited to Murasama) To do list: Charged shot New sound effects Murasama as a...8.1k downloadsupdated 4 y ago
• PPumpkin Maskby ErflyWeaker than the head of Krampus, but will always fire in the directions you expect. 3 room charge. Will appear in Treasure, Devil and Golden Chest pools.8.1k downloadsupdated 10 y ago
• IIsaac is sus characters and dripby 76561199080435951OH MY F*CKING GOD, ISAAC IS SUS This mod add two new characters: Amogus and the imposter and replace ventricle razor for vent Coop compatible Among us Drip8.1k downloadsupdated 5 y ago
• Ccat modby 76561198882315368I made a graphic mod to change some sprites like stoney, stone grimace, penny donation machine and turn them into golem cats and cat penny8.1k downloadsupdated 4 y ago
• MMixed Boss Collection Part 1by GuilhermeThis mod is a pack of all my boss mods, does to limitations of how many values a mod can save then It doesn't contain all the bosses, CLICK HERE for the part 2 of the mod and HERE for the part 3 of the mod it also features it's own menu config to change which bosses do you want and which ones wit...8.1k downloadsupdated 3 mo ago
• NNo Useless Heartsby Iris HeartThis mod makes every base game character able to pick up and utilize any base game heart! Details below. This mod is a mainly a compilation mod of my other smaller mods that are aimed at individual characters, except for Blue Baby who doesn't have his own separate mod by me, because such mod exis...8.1k downloadsupdated 4 y ago
• DDenis (+11 unlocks) [RGON]by Dracula joeThis mod requires REPENTOGON, it will not function properly without it! Say hello to Denis (and his offspring)! Denis' Mechanics Denis can't fire tears and must instead rely on his horde of Minisaacs to attack for him. - He can charge up to mitose a new Minisaac, and can have more Minisaacs the h...8.0k downloadsupdated 18 mo ago
• TThe Binding of Brazil (AB+)by TCDubs✎ 𝗥𝗲𝗽𝗲𝗻𝘁𝗮𝗻𝗰𝗲: --------------- A Tradução Brasileira de "The Binding of Isaac: Afterbirth +" ~Todos os Itens e Suas Próprias Descrições ~Pílulas, Cartas, Runas e Suas Descrições ~Alguns Nomes de Bosses ~Os Desafios ~O Bestiário ~Interface ~Todas as Conquistas ~Booster Pack 1,2,3,4 e 5 ~Andares ~ S...8.0k downloadsupdated 8 y ago
• BBrainrot Edition!by 76561199844292366Those who know..💀7.9k downloadsupdated 18 mo ago
• CCricket's Tailby SalvageReusable Chest Generator Active Item - 3 Room Charge Generates a chest with a higher chance of a special chest than usual! Chest Probabilities Normal Chest: 40% Spike Chest: 20% Red Chest: 20% Golden Chest: 10% Stone Chests: 9% Angel Chests: 1% Itempools: Treasure Room Pool Shop Pool Golden Chest...7.9k downloadsupdated 10 y ago
• GGolden death certificateby 76561198819178327Golden death certificate. This certificate is like normal, but he's not disappear. Made for fun "Are you dead again?" Quality: 4 Charges: 32 Pools: Treasure, Secret, Greed Treasure Game does not show more than 12 charge bars, so the charge is displayed incorrectly.7.9k downloadsupdated 5 y ago
• HHealth Insuranceby ☢ Nato Potato ☢Health Insurance is a custom active item which allows you to buy heals before you need them. Using Health Insurance takes 3 coins from you (not working if you have less) and turns heart pickups in the room into coins, when you have empty heart containers it will heal you half a red heart for each...7.9k downloadsupdated 5 y ago
• Bbuwenby 76561198347365682=BuWen Mod= 【Mod内容】 ①共计580 左右新的道具。 ②30位新角色（15表角色+15里角色） ③7种mod特有角色属性(基础攻击力、暴击率、暴击伤害、攻击力加成、最终伤害、技能加成、冷却缩减) ④34种“精英技能”；全新机制，怪物生成时有概率被赋予随机技能效果，每个“精英技能”有着各自各样的效果 ⑤12种“精英怪物”；全新怪物，不同怪物有着自己的攻击方式以及特殊机制。 ⑥添加伤害飘字显示，反馈拉满。 ⑦35 种以上新的卡牌、32 种以上新的药水效果、新的8种套装效果。 ⑧空想神话装备体系（完美还原崩崩，膨胀的开始） ⑨难度选择机制，可更具游戏进程和发育情况修改难度。以及...7.9k downloadsupdated 8 d ago
• GGood Deals [FIX]by 76561198865227624Increases the chances of good items in deals and adds new predictions to the fortune teller machines The mod no longer conflicts with other mods that add new items7.8k downloadsupdated 4 y ago
• NNew Character: Ennui!by PoondaedalinIntroducing Ennui: the root of all worldly sins! (or at least some of them) - Can swap between one of eight aspects with unique upsides and downsides! - Risk-reward system stemming from overusing one specific sin over others -- A full set of 15 unlocks items related to the character! - Hopefully...7.8k downloadsupdated 3 y ago
• MMORE no more symbolsby 76561199175201857No More Symbols by hemomaddie is a great mod that replaces the textures of the "symbols" items in the game. This mod tries to expand that amount, by imitating the style of hemomaddie's items for other mods with their respective symbols. This mod is compatible with: - Repentance Plus! - Andromeda...7.8k downloadsupdated 4 y ago
• TThe Librarian [Ab+/REP]by AgentCuccoThis mod has been tested on rep to work fine, but it might be a bit unstable. Additions This mod adds a new boss to the game: The Librarian. This boss has a 25% chance of appearing in libraries (similar to Greed). The boss possesses two different phases, however the second phase is exclusive to H...7.8k downloadsupdated 6 y ago
• DD6 Neco arcby 76561199520750748D6 is now neco arc! With sound effects! Buranyuu!7.7k downloadsupdated 3 y ago
• BBerserk! The Crucible Blade (Doom Slayer Swort) [Rep]by 76561198828705706RIP AND TEAR... I recomend complement whit this mods: Enjoy :) Esp: Recomiendo tener instalado con estos mod: Disfruta :)7.7k downloadsupdated 5 y ago
• NNinja Logby ☢ Nato Potato ☢The Kawarimi Log or 'Ninja Log' is an item that can be used to escape danger by having it take your place right as you would be attacked. To use the 'Ninja Log' move to a good spot and activate the item to set the position, then the next time you would take damage in that room instead of being hu...7.7k downloadsupdated 2 y ago
• Aalt. Book of Secrets sprite!by ViscerANow the book's sprite is more reminiscent of its effects. Make sure to leave your feedback in the comments, and don't hesitate to recommend any other sprite tweaks you would like to see from me in the future! For your convenience, I'm uploading every sprite tweak separately, so that if you don't...7.7k downloadsupdated 5 y ago
• Tthe binding of ICGby 御坂14144号WHAT?? UPDATED?? I thought the author was missing in Bermuda or somewhere?! OKOK, the REP update finally come, which fixed most of bugs and made some balance adjustment. ☆ 2 New Characters！ ICG A magical agent who specializes in manipulating rocket-propelled dolls(WTF)/b] · Starts with: - ICG Pro...7.7k downloadsupdated 5 y ago
• CCobson (Beast resprite)by 76561198338773226HWABAG Bone chilling, spine tingling, genre redefining, slow-burn resprite mod that will change The Beast with Cobson. no 'p embedded.7.7k downloadsupdated 3 y ago
• [[REUPLOAD] Aladar's Bomb Items Respriteby 76561198391425301Aladar, one of the, if not the best, spriter of Isaac has left internet, making his profile private and removing all the mods and amazing sprites and resprites he has done, sadly. I have a backup of most of the mods he had, and I'm reuploading them for the people who liked them, to still be able...7.5k downloadsupdated 17 mo ago
• SStrategy Guideby RyouMan, don't you just hate it when you're having a pretty decent run, but then of course you have to fight 'that' enemy, and you really don't want to deal with that situation right now. No longer will you be subject to such situations with the great new addition of the Strategy Guide™! Just one use...7.5k downloadsupdated 10 y ago
• MMorthosItemsby MorthosMorthos' Items is a small itempack for afterbirth+. It adds 3 active and 6 passive items to the game, added to various item pools. Any feedback is appreciated. For those of you who like to know the effects of the items before picking them up: Passive: Heritage, "Money = Tears" - Gives you a -1 te...7.5k downloadsupdated 10 y ago
• SSyringes+by NyxreThe Syringes+ Mod adds a variety of different Syringe based items to the item pool. Future updates will add more items, pills, and a new character. Current Item List: Passives: - Used Needle (Reduces Fire Delay) - Morphine (Reduces Speed, Gives 2 Spirit Hearts) - Booster Shot (Increases Speed, In...7.5k downloadsupdated 10 y ago

621 active items mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.