The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth bosses mods
Everything filed under bosses by its own author, ordered by how much it is used.
475 bosses mods, most downloaded first · newest update 26 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
475 bosses mods
- Beast Madness Combatby 76561199086539150This mod aims to change all Harbingers and the Beast into Madness Combat characters :The Beast will be added soon Big thanks to my friend Jebus for all the sound effects please check out their Madness mods as well Changes Bosses: Death Conquest Ultra Death Ultra War Ultra Pestilence Ultra Famine...5.0k downloadsupdated 5 y ago
- delirium spunch bopby WEMZno more telefragging *thud* thanks a lot for 1,500 downloads!5.0k downloadsupdated 5 y ago
- Delirious R Key!by 76561199022951369Ever wanted to get more completions marks past Delirium? Me too! This mod makes it so after defeating Delirium, it drops a new item called "Delirious R Key". This item works nearly identical to R Key, except that it grants 6 broken hearts. This allows the player to get more completion marks in a...5.0k downloadsupdated 3 mo ago
- Caseoh As Gluttony + Super Gluttony!by 76561199497853545Ever thought: "Man, I wish the boss Gluttony looked like an overweight streamer!" Well, your wish has come true! This mod replaces the sprites for both Gluttony bosses to look like the streamer Caseoh. "peak isaac modding" -SuperBR "LITERALLY UNPLAYABLE, EVERYTIME HE WALKS HE LITERALLY AND I MEAN...4.9k downloadsupdated 2 y ago
- The Beast but it's Gokuby 76561199001135640I've had this funny idea in the back of my head, and I had decided to make it. This is not at all supposed to be a very high quality mod and was mainly just something made for fun, but I hope you all enjoy goku from the binding of isaac.4.9k downloadsupdated 4 y ago
- [Rep] Devil Statues Plusby ClocksAs of Repentance we all know that devil deals are not so enticing anymore and angel rooms are "meta".. With this mod one can challenge the dark lord's henchmen for more spooky loot ;) Should be easy to figure out, but in case you want to jump straight to it: You must take a devil deal and then bl...4.9k downloadsupdated 5 y ago
- Pulled Teeth [AB+ Ver.]by KrowskiPulled Teeth for Repentance now available! Have you ever thought to yourself, "This game has too many teeth?" Of course you have! And now the solution is finally here! Pulled Teeth removes any trace of teeth from the game for all of your gummy, detoothed needs! After 10 14 too many months of hard...4.9k downloadsupdated 5 y ago
- Mausoleum Visageby 76561198374458982The Visage has been re-added to the Mausoleum! ----------------------- 𝐌𝐚𝐮𝐬𝐨𝐥𝐞𝐮𝐦 𝐕𝐢𝐬𝐚𝐠𝐞 ---------------------- Adds The Visage into the Mausoleum boss pool with a weight of 1 The Gehenna Visage still exists, this mod merely adds it to the Mausoleum, too Contributors Silist and Kittenchilly Specia...4.9k downloadsupdated 2 y ago
- Amongo Beastby 76561199111487810How is that no one has made a mod like this yet??? (Now officially part of The Grinding of Isaac!)4.9k downloadsupdated 5 y ago
- SCROTO MOD + (Boss Resprites n' Tweaks)by 76561198893672165Scroto's note: An update of a resprite mod I made in the past. Now implementing better resprites, new animations, new champions and new portraits! This mod requires REPENTOGON due to the custom VS screens of the final bosses. Special thanks to RATINSURACE for helping me with the code, to CY for h...4.8k downloadsupdated 2 y ago
- WEEGEE over Satan (+Mega Satan)by 76561198452053394NEW UPDATE! You may need to reinstall the mod for it to work. || OBEY WEEGEE, DESTROY MALLEO || This is a mod that replaces Satan with Weegee, the infamous character known from the golden days of Youtube Poops. Mega Satan is also replaced with his much more powerful form, Giga Weegee, based on th...4.8k downloadsupdated 3 y ago
- Bill Cipher Modby dicker mannReplaces the boss "the forsaken" with Bill Cipher from Gravity Falls4.8k downloadsupdated 10 y ago
- [REP] Pee-Wee [UNMAINTAINED]by StelleThis mod REQUIRES StageAPI. For champions to work, Repentance Boss Champions is needed. Poop has dominated The Binding of Isaac since forever. Well no more! Introducing Pee-Wee, your resident piss monster! She is the most vile creature you'll ever encounter in Dross. -Credits-4.8k downloadsupdated 4 y ago
- Hp Bar For Enemies (REP+)by PxntxrezWARNING! This mod will no longer receive updates! I am currently working on an entirely new version that will feature: all bugs fixed, all errors addressed, and much more! ------------------------ Bug Fixes: Fixed bug with mirror world Исправление ошибок: Пофикшен баг с зеркальным миром ---------...4.8k downloadsupdated 22 mo ago
- giga c.h.a.dby 76561198994527278I made C.H.A.D as the Giga Chad! Important notes - - - - Little chad is included in the mod - When c.h.a.d spawns a fly, there's some bugged pixels on top of him. (I'll fix it soon)4.8k downloadsupdated 3 y ago
- Markiplier as the beastby Leylyneshello everybody my name is markiplier and welcome to five nights at isaac's Replaces the beast with Markiplier from Markiplier4.7k downloadsupdated 3 y ago
- bestia feet boss(budang)by 765611990258689074.7k downloadsupdated 22 mo ago
- PIBBLEby 76561199357336443Logan if you are reading this, please let me out of the basement I want to speak to my wife and kids4.7k downloadsupdated 22 mo ago
- Boss Resprite - The Forsakenby FerpeResprited and reanimated The Foreskin!! Includes champions and Delirium variants! If you think his fight is very lame then take a look at the Improved & Reworked Foes mod! (note that you will need to disable my resprites if you use this mod to avoid bugs): The Black Bony in the preview image is f...4.7k downloadsupdated 3 y ago
- (AB+ ONLY) 8-bit Binding of Isaacby Fante--- Update: 2021.10.01--- The 8-bit Binding of Isaac mod is incompatible with Repentance. The possibility of a future update remains unknown, mostly because this mod has been sorta kinda implemented with Repentance with the changes to Retro Vision. Chances are that the development of this mod is...4.7k downloadsupdated 6 y ago
- Sonic Mod [Beta]by Ao JonesiUPDATE: Thank you so much to everyone for checking out my mod! We've nearly hit 500 subscribers, and I'm working on an update that should finish Tails and properly fix Sky Sanctuary asap, along with other awesome features! Introducing the Sonic Mod, a creation made in my spare time as a love lett...4.7k downloadsupdated 9 y ago
- Monstro Variety Packby The_Evil_PickleA very silly mod that randomly changes Monstro's appearance each time he is encountered. All Monstros are from other mod-makers (list below). When playing on normal difficulty, the changes are only graphical. On hard difficulty, however, some of the different monstro skins have special abilities....4.7k downloadsupdated 9 y ago
- Death with a robeby nerfexusgives Death a robe4.7k downloadsupdated 4 y ago
- Ultra Headless Horsemanby 76561198855158338Ultra Headless Horseman has a 50% chance to replace Ultra Famine, Ultra Pestilence, or Ultra War during The Beast's boss fight. With Mod Config Menu, this can be changed to have Ultra Headless Horseman appear in addition to the other harbingers, as well as having his chance to appear be modified....4.6k downloadsupdated 18 mo ago
- Ice Princessby 76561198353126873This mod REQUIRES StageAPI and Revelations to function. -Description- Within the cold walls of the Glacier, A new foe rises to take center stage. The Ice Princess has set herself a goal to become the greatest figure skater In the Glacier. and just so happens you've shown up right before her pract...4.6k downloadsupdated 3 y ago
- (OUTDATED DO NOT USE) Another Graphical Overhaulby RareFor years, there have been things that have bothered me about Isaac. It's mostly small stuff, but it's there, and I've finally decided to go out and fix it. Here is the result of my work, as well as the work of many others (all used with permission), combined into one convient mod. -Screenshots a...4.6k downloadsupdated 9 y ago
- Mom with Timbsby Gorbo GrandmanUpdated version of Mom with Timbs now hand-drawn by my homie.4.6k downloadsupdated 5 y ago
- Sethby 76561198353126873This mod REQUIRES StageAPI and Revelations to function. -Description- Where there's sand, there's bips, a collective army of castles and storms, but who is one to command this fleet, Only Seth! The God of the sand and head honcho fo the Sandbip mafia. and very possessive of his crystal eye. not t...4.6k downloadsupdated 3 y ago
- Tung Tung Devil replaces Satanby 76561199311872895dont worry hes with tung now TUNG TUNG DEVIL REPLACES SATAN only replaces statue, not boss sorry not sorry maybe if this gets on front page of workshop ill consider it winkwinkwinkwinkwink tung tung god here:4.6k downloadsupdated 7 mo ago
- Ultra Conquestby 76561198855158338Ultra Conquest has a 50% chance to replace Ultra Death during The Beast's boss fight. With Mod Config Menu, this can be changed to have Ultra Conquest appear in addition to the other four horsemen, as well as having his chance to appear be modified. Compatible with: -Mod Config Menu -Enhanced Bos...4.6k downloadsupdated 2 mo ago
- The Beast is now the Hatsune Miku Nendoroid Plushieby 76561198986173332Makes The Beast into the Hatsune Miku Nendoroid plushie. Does not change any of the horsemen.4.5k downloadsupdated 3 y ago
- The Mancer Bossby GuilhermeBloat is tired of staying in Depths/Necropolis, so it learned telepathy and it's new home is Mausoleum, you can find it at the Boss Room. UPDATE: there's a modpack containing all of my bosses now, check it here: when It's candle is active you can stay on it's sides as much that you want, but I do...4.5k downloadsupdated 3 y ago
- eater of cellarby 76561199164501307Changes Pin to Eater of Worlds from Terraria4.5k downloadsupdated 4 y ago
- William Afton (Springtrap) Is Mom's Shadowby HengusM"I ALWAYS COME BACK." -William "Springtrap" Afton (Deceased) Run from the EVIL child murderizer, William Afton. Or his ghost. Or Springtrap. Or his digital remains. Or whatever the hell he is. Looking for more children to kill, 'Ol Willie has set his sights on a new crying child to bulldoze. Litt...4.5k downloadsupdated 19 mo ago
- King Dedede Bossby Guilhermethis mod adds a new boss, this time from the Kirby Franchise I (FINALLY) show here King dedede, it also includes a variant which is Masked Dedede. King Dedede appears at Caves/Catacombs, while Masked Dedede appears at Womb/Utero this mod is included in a modpack that contains all of my bosses now...4.5k downloadsupdated 2 y ago
- Trollface Dogma + Trollface Beastby Eternal NecromancerThis mod replace Dogma and Beast (+Ultra Harbringers) into your favourite meme and ruler of everything - Trollface! Why? Because, why not! Special thanks to fly_6, for testing this mod.4.4k downloadsupdated 6 y ago
- Delirium Take Overby VideoGameNewsDelirium took over the basement can you overcome this nightmare or will you fall into the darkness. I replaced every Boss and Monster. And change all the levels and other stuff. I draw every monster to look like Delirium. Enjoy. Like my addon? Have any problems with it? Feel free to comment. Work...4.4k downloadsupdated 10 y ago
- Tenebre Rosso Sangue over Beast and Ultra Horsemenby palookaReplaces the Beast and Ultra Horsemen music with a mix of the ULTRAKILL Tenebre Rosso Sangue tracks. Enjoy! Source:4.4k downloadsupdated 4 y ago
- Fallen Gabriel spawn a imp instead of a angelic babyby Guilhermedon't make any sense fallen gabriel spawn angelic baby, so, this mod makes fallen gabriel spawn a imp instead of a angelic baby4.4k downloadsupdated 6 y ago
- Isaac Ukranian 0.2vby DemabelThe Binding of Isaac Українською 1.0 v ВАЖЛИВА ІНФОРМАЦІЯ!! Дана українізація адаптована під англомовну версію гри, перед завантаженням перемкніть на неї, якщо використовуєте іншу. Крім того не забувайте щоб отримувати оновлення, вам треба повністю видалити папку з модом, зайти в гру. Скачати йог...4.4k downloadsupdated 3 y ago
- GoldenKeeperby 76561199091925974Changes everything below - Keeper and Tainted Keeper - Greed and Ultra greed (they share sprites with the characters) - Most of Keeper's costumes - Animations for the Greeds and Keepers - Wooden nickel - Eye of greed - Crooked Penny - Strawman - Keeper's sack - Keeper's kin Any mod that changes t...4.3k downloadsupdated 2 y ago
- Boss Resprite - The Gateby FerpeRe-resprited and re-reanimated a boss people often forget about, The Gate. Complete with its championa nd Delirium variants! This time it's a completely unique design, since I didn't like how my older resprite looked. If you still prefer the older version it's still available here: This resprite...4.3k downloadsupdated 3 y ago
- Caves n' Creatures!by Mr. SeemsGoodNOTICE This mod is a little unorthodox in the sense that it's very easy and prone to getting you stuck inside the minigame, one way or another. We also aren't the best coders. Should you ever find yourself in this situation, you should be able to exit and continue your run, in which you'll be sen...4.3k downloadsupdated 3 y ago
- D666by micromarioDescription: Reroll your soul Itempools: Treasure and devil Effects: (Active) If you have red health, the item takes two hearts away and gives you a random devil deal item If you have soul health, the item takes three hearts away and gives you a random devil deal item If you don't have health, th...4.3k downloadsupdated 10 y ago
- pou as monstroby Josigor4.2k downloadsupdated 5 y ago
- New Delrium Formsby 76561198993684021Have you ever fought Delirium and noticed that there was a missing Delirium sprite for one of the bosses? Delirium Forms+ fixes this by implementing sprites made by me! Delirium Form+ adds 3 new forms for - Bumbino - Reap creep - The Pile This is my first mod ever and first time editing Isaac spr...4.2k downloadsupdated 3 y ago
- Stoner Satanby 🅱️ean 🅱️oyThis graphical enhancement modification for the video game, The Binding of Isaac: Afterbirth+, adds a GIANT retexture of the Satan Statue. It updates his previously dull, grim face to a more relaxed mood. The use of this mod is intended to bring joy and comic relief to the more casual players.4.1k downloadsupdated 10 y ago
- Dogma Clickerby Phno 🐙"Having trouble with your TV? Just switch the bloody channel. Easy as that :v" It should be completely normal and logical that you can defeat an enemy, which comes out of the tv, instantly if you just turn off the tv. Right? Right. So, now this is possible with the clicker. The clicker remains it...4.1k downloadsupdated 3 y ago
475 bosses mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

