The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth bosses mods
Everything filed under bosses by its own author, ordered by how much it is used.
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects745Player Characters713Active Items625Bosses490Familiars446Pickups409Music405Enemies369Rooms352Trinkets340Cards254Challenges201Floors173pills158Hazards150Removals148Shaders143babies115
490 bosses mods
- Fat Teto Beastby 76561199549838612The Beast is now Kasane Teto, and the Horsemen of the Apocalypse are now Miku, Gumi, Neru, and Luka! P.S. The Horsemen of the Apocalypse have only been redesigned from the moment you see them; in the future, there will be a complete rework of the bosses themselves. There are also plans to add spe...7.4k downloadsupdated 10 mo ago
- bossroulette_V2by 허농이✅ This mod was created by the livestreamer Isaac Oh Heon-Young. ✅ Purpose: A content-focused mod designed for veteran players who have achieved Dead God. ✅ How to use: Press the I key to randomly select a boss. ✅ Notes: If the boss route is set to Delirium, the Hush door will open regardless of t...7.4k downloadsupdated 8 mo ago
- shuodedaoliby 76561198845833421Monstro replacement with Shuodedaoli7.4k downloadsupdated 3 y ago
- Abortionbirth Revelations Compatibilityby NarilliaIf you're one of the lunatics who plays Revelations's Glacier, but wish you could still play the far superior Northern Glacier from Abortionbirth, this is the mod for you! Patches a compatibility issue in Abortionbirth Pack 2: The Heckoning, to allow playing inferior mods alongside it. Also adds...7.3k downloadsupdated 9 y ago
- Neko Repentance Bosses!by transgirlcathyUh oh! Everything is cats! ...At least all the Repentance bosses are! How did this happen?! This mod changes all bosses added in Repentance to have cat ears. It also gives cat ears to big horn. This effects Vs. screens, in game sprites, and a few extra hidden easter eggs for you to find! Leave a...7.3k downloadsupdated 5 y ago
- Best Isaac Musicby 76561199030889749Isaac has a lot of pretty good music of various composers, why not extract the best of the most of them??? Like other the music mods, this one replaces almost all Afterbirth/Repentance music tracks for others than I think are better, there are some compositions of DannyB (Flash Isaac), Mudeth (An...7.3k downloadsupdated 3 y ago
- Thicc Siren (Re-Upload)by 76561199229505861I am uploading this mod because the original creator яйца пришли made it a troll for some reason. Flowey face in the picture is from this mod: if you want to spawn her on debug console type: spawn 904.07.3k downloadsupdated 2 y ago
- the destroyer over angelsby 76561199724434256this mod replaces angel statue and all angels sprites (expect Delirium's forms) to The Destroyer and his champion version from Mewgenics :steamhappy: view my workshop for more mods with Mewgenics my channel: author of the art in the background of the thumbnail of mod👀: bellyboi137.3k downloadsupdated 3 mo ago
- Satan in Devil Rooms (+Fallen Angels)by StlkngneThis mod was inspired by Devil Statues Plus and Bombable Devil Statue. There's a devil statue in each Devil Room. Now, sometimes it'll turn into a Satan fight. Once you defeat Satan, each devil deal item will cost a single point of damage rather than one or more heart containers. Note: After you...7.3k downloadsupdated 9 mo ago
- Blastocyst is King Slimeby Ivan_CrysisBlastocist now is King Slime . . . just that . . .7.2k downloadsupdated 5 y ago
- Biblically Accurate Angelsby Hatless(MOD WAS MADE FOR AFTERBIRTH+) Angels in the Bible are apparently described as disturbing masses of flames and eyes, which I thought would be neat in a game like Isaac. This mod changes: - The Angel Statue Sprite. - Uriel's Sprite. - Gabriel's Sprite. - Delirium Uriel's Sprite - Delirium Gabriel'...7.2k downloadsupdated 6 y ago
- Neko Colostomiaby transgirlcathyYou knew this was coming. Credit to The Binding Of Isaac discord for telling me to do this. Also credit to my girlfriend for telling me to make the poop bombs have ears. I didn't do that but it was a good idea.7.2k downloadsupdated 5 y ago
- She Got An Educationby OctotronChanges the Siren to have some nice glasses and a suit because she got an education. Isn't that pleasant?7.2k downloadsupdated 5 y ago
- Ankha as Rag Man (FIXED)by 76561198977272111hello!! this mod is an updated version of a mod uploaded by the user PizzaTime, although the sprites wasn't made by them (i think they were taken from a nsfw isaac mod por AB+? idk) i've made some changes, this is the uuuh.. changelog? - fixed visual bugs - reubicated the bossname and portrait fr...7.2k downloadsupdated 4 y ago
- Deep laboratories (AFTERBIRTH PLUS VERSION)by Mogumi-------------------------------------------------------------------------- DEEP LABORATORIES FOR REPENTANCE IS OUT! -------------------------------------------------------------------------- IMPORTANT! Don't force this mod in Repentace! the new DLC changed a lot of sprites and how things work in...7.1k downloadsupdated 6 y ago
- NotYourSag's Siren w/ Red Hair [REUPLOAD]by EMORYGives Siren the appearnace that NotYOurSagittarius draws her in, but with red hair. Comfy sweater. Red hot red-head. Original creator deleted the red-hair variant. Art by NY_Sagittarius7.1k downloadsupdated 4 y ago
- Bygone Over ???by FissionMetroid101"The end is nigh!" It always bothered me how ??? was always just a reskin of Isaac, even if he plays differently... Buuuutttt seeing as Bygone is technically also blue baby, I thought it'd make a perfect visual replacement! This mod features NO gameplay changes, but it does include a slight visua...7.1k downloadsupdated 5 y ago
- Baby Plum doesn't dieby Richard MoelleuxMakes it so when you deplete Baby Plum's health, it just plays its leave animation instead of the death animation (yes that's it). No more heartbreak :(7.1k downloadsupdated 5 y ago
- Cobson (Beast resprite)by 76561198338773226HWABAG Bone chilling, spine tingling, genre redefining, slow-burn resprite mod that will change The Beast with Cobson. no 'p embedded.7.1k downloadsupdated 3 y ago
- Luncheon (Tapeworm boss)by MsGummyLuncheon is a new boss inspired from the mechanics of Tapeworm, a board game by Edmund McMillen! Rather than directly attacking the player, Luncheon will throw up his insides which are swarming with wriggling tapeworms, who each attack differently depending on their segments. (Requires StageAPI)...7.1k downloadsupdated 6 y ago
- Boss Resprite - Dingle + Dangleby FerpeShitpost moment Resprited and reanimated a shitty boss amirite poopy shitty farty haha caca poopoo brrrap Complete with its 3 champion variants + their Delirium versions! (I know Dangle isn't a champion but it might as well be one come on)7.0k downloadsupdated 4 y ago
- Improved Animation for Satanby GuilhermeThis mod improves the animation of satan while he is attacking in phase two. His wings will not be closed while attacking anymore, now he is always flying7.0k downloadsupdated 4 y ago
- Caco Plumby График ЗапоевThis mod replaces visual of boss Baby Plum to the visual of Cacodemon sprites from Doom 2. Animations also fully work. ✦✦ Please don't forget to push the like button and leave comment! ✦✦ If you want to Caco Plum to get massive explosion when he dies (g-fuel), you want to take this! You also may...7.0k downloadsupdated 4 y ago
- Boss Resprite - Daddy Longlegs + Triachnidby FerpeResprited and reanimated both Daddy Longlegs and Triachnid. The attack where they stomp a lot drove me nuts because the animation didn't convey them being unreachable by Isaac's tears, so I did the logical thing of redoing everything. Complete with their own Delirium variants! This is now include...7.0k downloadsupdated 4 y ago
- Family Guy Death Pose for the lambby BarneyReplaces The Lamb's body sprite with the family guy death pose. Works for both The Lamb and his Delirium form. Will probably be incompatible with other Lamb resprites, hit me up if it breaks your mod and I'll gladly try to fix it. Thanks for getting this to the popular section, I hate all of you6.9k downloadsupdated 4 y ago
- Boss Rush Plus - More Varied Boss Wavesby Clove G.Everything is Terrible! More Foes have Entered the Boss Rush! Boss Rush Plus is a mod that updates the Boss Rush to include the Afterbirth+ bosses and all the Chapter 4 Bosses that were missing. Alongside Mini-Bosses such as the Sins, their Super Variants, and Krampus. As well as the Repentance B...6.9k downloadsupdated 4 y ago
- the binding of maggy's toy box and WOB isaac's secret stashby 76561199032451894个人整合包,非原作者,模组来源: maggy's toy box maggy's toy box reborn WOB isaac's secret stash Rest with a pretty lady Personal modpackage, I AM NOT THE ORIGINAL AUTHOR, mod source: maggy's toy box maggy's toy box reborn WOB isaac's secret stash Rest with a pretty lady 有一个模组不兼容所以以压缩包形式保存在整合包的文件夹内 There's a mod...6.9k downloadsupdated 18 d ago
- Road Roller!by lesserStar-Changes Monstro into a road roller from jojo -So monstro's tooth becomes a Road roller item -the name of the item is not chenged (idk how to do that) Sprite is from Jump Ultimate Stars6.9k downloadsupdated 8 y ago
- flash angelsby 76561198339469043mod that makes angels look much better if you played flash isaac 80 years ago6.9k downloadsupdated 3 mo ago
- Steve over Hornfelby 765611990681377476.8k downloadsupdated 10 mo ago
- Better Fallen Angelsby *{~kamenshchik~}*A simple mod that alters appearance of the fallen angels that can be seen at mega satan boss fight. Now they look more demonic. Also, feel free to change this mod as you want. Contact me if you discovered bugs.6.8k downloadsupdated 2 y ago
- Salem | The Soul Seekerby AgentCuccoSalem Approaches. The trials have begun, and the bells of awakening toll. The Soul Seeker rises once more, to take by force what was thought lost. Heed thy warning, for you will die, to outrun her is a foolish man's fight. Speed's the key, the bells ought not toll, for if they do, the Witch shall...6.8k downloadsupdated 17 mo ago
- WhiteNight Dogmaby 76561198365949909Changes Dogma to WhiteNight Aleph Abnormality from games Lobotomy Corporation and Library of Ruina Features: - WhiteNight as Dogma - New music - New sound effects - Styled visual effects of second phase 🔑🌙 Project Moon6.8k downloadsupdated 5 mo ago
- Brindle.by 76561198977878686Includes: brindle note: brindle is owned by zephyr!!!6.8k downloadsupdated 4 y ago
- The Grinding of Isaac: Meme Hellby XXL Pizzaytp sexer ruins isaac's life Replaces almost every sound effect and song in the game with meme trash and YTP humor. Features custom graphics occasionally. BEFORE PLAYING: Other mods that change player animations and sounds may cause compatibility issues. For the intended experience I reccommend d...6.7k downloadsupdated 3 y ago
- Dogma Fidget Spinner Attackby smemmoChanges the spinning attack of Dogma to a fidget spinner.6.7k downloadsupdated 5 y ago
- Cave Angler bossby Mr SexNew boss for flooded caves, thanks to All-Seeing for help with the sprite, and numerous people on the Modding of Isaac discord server for help with code6.7k downloadsupdated 3 y ago
- Greedier Bosses (OUTDATED)by slapjakThis mod is outdated! You can subscribe to the new, expanded version here Greedier Bosses is a cosmetic mod that will include Greed-themed reskins for all bosses that appear in Greed mode. Reskins only appear in Greed mode by default, however that can be changed via Mod Config Menu . Using Mod Co...6.7k downloadsupdated 5 y ago
- Scooby Doo Creepy Run replaces Chased By Deathby 76561199035670843This mod replaces Chased By Death with the theme song from Scooby Doo Creepy Run!!!! I saw a bunch of Tiktok comments asking for this and a bunch of videos editing it into the game so I decided to make it into an actual mod lmfao :P (THIS IS ONE OF TWO MODS I'VE MADE ABOUT SCOOBY DOO CREEPY RUN!!...6.5k downloadsupdated 4 mo ago
- WhatsApp Whistle for Dingleby EthanChanges Dingle's whistle to the whatsapp notification6.5k downloadsupdated 3 y ago
- Re: Item Chests Before Motherby StlkngneDoesn't this already exist? Yes This mod requires REPENTOGON. It uses a newer Repentogon API that properly supports Guppy's Eye. The room before Mother will contain 4 golden chests with treasure room items inside. If you have The Left Hand trinket then you'll get devil room items instead, and hav...6.5k downloadsupdated 9 mo ago
- HOMERO song for every bossby cringecoreadds better song over every boss fight HO ME RO HO ME RO HO ME RO6.5k downloadsupdated 7 mo ago
- reap creep respriteby 76561198876704734this mod polishes reap creep's sprites a lil to be more up to snuff in comparison with the other repentance bosses commissions still open! hit us up!6.4k downloadsupdated 3 y ago
- Godmode汉化模组by 76561199253021281⚠️该模组已过期,请在我的合集里下载新的EID汉化模组⚠️ 这是一个对Godmode Achieved模组的EID进行了汉化的模组 请确认你已安装了Godmode Achieved和EID 汉化作者:B站@青灼QWQ 感谢B站@长山小春0213 提供的汉化帮助6.4k downloadsupdated 23 mo ago
- lebron sunshine over dogma versus screenby 76561199121244854this mod does things (doesn't change Dogma itself) you are my sunshine my only sunshine6.4k downloadsupdated 2 y ago
- The Peepingby Jean-Alphonse6.4k downloadsupdated 10 y ago
- Death Wishby ☢ Nato Potato ☢The Death Wish active item allows you to challenge extra bosses and earn extra items. When used you are teleported to a new boss room separate from the one with the exit trapdoor, the boss you fight is totally random, but does not include bosses which are marked on the completion note like satan...6.4k downloadsupdated 8 mo ago
- Tennistulaby SprSnpr_A mod that makes the Mother fight just a little bit less unbearable... Changes: - The sprite of the Corpse version of Fistula Doesn't Change: - The normal fistula sprite - The melee swing sound effect (only in the video)6.3k downloadsupdated 4 y ago

