The Binding of Isaac: Rebirth mods
The Binding of Isaac: Rebirth bosses mods
Everything filed under bosses by its own author, ordered by how much it is used.
475 bosses mods, most downloaded first · newest update 26 Oct 2026
AllGraphics1.9kLua1.9kTweaks1.6kItems1.3kSound Effects740Player Characters709Active Items621Bosses475Familiars442Pickups405Music403Enemies359Rooms347Trinkets336Cards248Challenges198Floors169pills155Hazards145Removals143Shaders136babies112
475 bosses mods
- The Haunt is smilingby Criti-ChanThe Haunt is happy to see you and greet you with a big beautiful smile :) I hate this as much as you do.6.0k downloadsupdated 6 y ago
- Spongehushby SlimesauceBased on a fever dream I had Changes Hush to Spongebob as depicted in the one episode where he claws his way out of the womb, gasping for air and slowly suffocating to death, just like in the Bible this mod changes absolutely nothing about skinless hush, don't try it out I am deeply sorry6.0k downloadsupdated 6 y ago
- Markiplier Greed Deathby 76561199127032644Replaces the death statue and death scream of Ultra Greed with Golden Markiplier.6.0k downloadsupdated 3 y ago
- Better Haunt Tell (REP COMPATIBLE)by eyeguyA mod that changes the Haunt's bullet attack to have a more visible windup, giving the player more time to evade.5.9k downloadsupdated 9 y ago
- Practice Modeby tomorrow's wordle todayWhere do you stand during Hush's continuum? How do you avoid Dogma's laser? What does Mother even do? This mod adds a custom challenge to practice against the five non-greed-mode superbosses: Mega Satan, Hush, Delirium, Mother, and Dogma & Friends. After you select the boss, you'll get a minimum...5.9k downloadsupdated 5 y ago
- Dr. Zomboss!by knuxchuxReplaces Mom with Dr. Zomboss, the Brainiac Maniac from the Plants vs. Zombies series. Also affects Mausoleum Mom. Original PvZ graphics by Rich Werner, and edited by me.5.9k downloadsupdated 4 y ago
- The Binding Of Doki Doki Afterbirth+by BenShyMaru(Obviously this contains DDLC spoilers) Well... one day I happened to do some DDLC sprites ... and in the end I decided to make a kind of "Mini mod" Things that the mod has at the moment (This version is very WIP): - 4 Characters (Normal Dokis) - 4 Repainted Items Things I plan to do: - 4 more ch...5.9k downloadsupdated 8 y ago
- Goth_Mommy.mp3by 76561198450700216Purely Cosmetic mod Reskins The Mother Boss, including Delirium Forms Reskins the Items: Moms Underwear Moms Heels Moms Bra Moms Eye Moms Contact Moms Coin purse Moms Perfume Moms Pearls Reskins Portaits: Moms Boss Portait Moms Nightmare 9 Moms Hand All of Moms Champion forms Moms Bra giantbook E...5.9k downloadsupdated 3 y ago
- Boss Resprite - Mama Gurdyby FerpeResprited and reanimated this uh... boss that literally noone remembers. I took a bit of inspiration from Mother. Just a lil' bit. I mean come on, her old spritesheet was so awkward. It was very unefficient with the space and the cut-off looks so weird with the zoom level I use. Includes her Deli...5.8k downloadsupdated 4 y ago
- [AB+] Hush is now Garfieldby Concept Art Noelle HolidayThis mod turns the Hush into our favorite monday hating and lasagna loving cat! Garfield also threatens to kick Odie off the table when shooting tear lasers. Respriting by waterPsychiatrist (me bby). Expect an update before the year is over... hehehe5.8k downloadsupdated 7 y ago
- Unused Corpse Boss Variants!by PoondaedalinFun fact: Fistula, Teratoma, and Wormwood all have unique variants for the Corpse floor in the game's files! However, Fistula and Teratoma are used in a total of three rooms each, and Wormwood isn't used at all in-game, and when spawned in manually, Wormwood's unique graphics don't display, since...5.8k downloadsupdated 3 y ago
- Improved Lustby PACKGOD APOTHECARYA more lust-y lust and super lust with (a little too much) makeup. Includes some floating hearts! First time publishing a resprite mod, I might make more if I have the time.5.8k downloadsupdated 5 y ago
- Delirium Repentance Sprite Updateby 76561198876163522Das kinder (edmund) made bad delirhstrunten sprties, so i das dult made new better sphruntenhunten! In other words I updated some of the old delirium sprites to match their new repentance counterparts, alongside updating some I felt were a tad too "shiny" for my liking. updated/unshined sprites i...5.8k downloadsupdated 5 y ago
- Madness Combat Musicby 76561198369844905Somewhere in Nevada... Changes 60+ in-game songs to OST from Madness Combat, Madness Project Nexus Classic and MADNESS: Project Nexus Highly recommend to checkout Krivaan Madness mods they are awesome! | Leave noticed bugs in the comments | Menu - Madness Project Nexus: Theme Song Levels: Basemen...5.7k downloadsupdated 4 y ago
- Neko Steven(&Ash)by 76561198815141965Absolutely essential mod, Steven but cat :3 ash too now I guess (Steven's delirium form) IF YOU READ THIS GO SUBSCRIBE TO THE PETRIFIED POU MOD5.7k downloadsupdated 5 mo ago
- Eternal Championsby The_Evil_PickleAdds rare and powerful Eternal variants for many enemies and bosses. Also features a challenge in which nearly all enemies that can spawn as eternal variants will do so. For a more comprehensive list of which enemies have eternal variants so far, as well as detailed descriptions of each eternal e...5.7k downloadsupdated 9 y ago
- More Championsby 76561199034036813Most champions in this mod are harder then their normal counterparts, sometimes significantly. If you don't want an extra challenge, this mod may not be for you. I always really liked the idea of champions. Fighting a stronger enemy for an extra reward, so... I decided to add my own. But, I could...5.7k downloadsupdated 4 y ago
- Shynova respritesby Shynova--Shynova Resprites-- This mod resprites over 50+ items, trinkets, and multiple enemies that you'll find in the game, updating their visuals to a dazzling degree! Any feedback and suggestions are welcome, and if you can, share this with your friends! :D -------------------------------------------...5.7k downloadsupdated 2 y ago
- PLACENTA+by VerlyonDernière MàJ : 13.12.2019 : v1.1 Les voix ont été ajoutées automatiquement! Ce qu'il reste à faire : - Toutes les cartes "XXX appeared in the basement"; - Certains titres ne fonctionnent pas proprement au niveau des accents; - Quelques menus du départ, dont le bestiaire; - La voix de l'intro. Il...5.7k downloadsupdated 5 y ago
- better scythesby 76561198876704734This mod improves the base scythe sprites by making them not just two colors.5.6k downloadsupdated 6 y ago
- TF2 for Ultra Harbingers + The Beast!by StaccatoI was one of the many people who subscribed to the original mod that gave Ultra War the voice of Soldier, from Team Fortress 2 (and was later updated for all the Harbingers). Recently, while fighting the Harbingers, I noticed the voicelines were no longer there. The original mod has seemingly dis...5.5k downloadsupdated 5 y ago
- Tung Tung God replaces Angel Statueby 76561199311872895Replaces the Angel Statue with Tung Tung God. NO AI WAS USED TO MAKE THIS TUNG TUNG DEVIL OUT NOW:5.5k downloadsupdated 7 mo ago
- Among Us mega modpackby 76561198825922892This mod conjoins EVERY single among us mod on the Workshop, all credits go to all of the creators (go give them money and riches and also love) which are... Bloodshot eye: Isaac is sus: The Binding of Imposters: Giga Bomb: Monstrogus: Crewmate Plum: Crewmate Rotgut: Ejected Crewmate: Suspicious...5.5k downloadsupdated 5 y ago
- [FF:Reheated] Boss Rush Plus - Fiendish Editionby Clove G.Not compatible with Fiend Folio: Reloaded. For a version for Reloaded - Click Here Very Important: Make sure you also uninstall the vanilla version of Boss Rush Plus - More Varied Boss Waves before you install this one. Make sure only this is installed. Boss Rush Plus: Fiendish Edition is a Fiend...5.5k downloadsupdated 2 y ago
- Bad Apple Dogma TV FullAnimby 76561198882069947东方相关mod,把整个bad apple的动画嵌入和教条战斗时的电视机中,然后还把它的两个bgm替换了。 This is a touhou mod that plays the complete bad apple animation on dogma tv Only modified the animation of dogma and replaced its two bgm. 参考了以下两个mod:5.5k downloadsupdated 2 y ago
- It Lives realistic respriteby pasajeroAfter hundred of hours I find out that it was a fetus. Let's change that.5.4k downloadsupdated 11 mo ago
- Even Stevensby PermamissAren't you tired of always getting Little Steven from the Steven boss fight? Well, now it's up to your skill whether you get Steven or Little Steven! The boss you kill last will determine whether they drop Steven or Little Steven. Since it's harder to kill "Big" Steven last, this makes a skillful...5.4k downloadsupdated 3 y ago
- Baby Plum Titleby SprSnpr_Adds a little friend to the title screen This mod is compatible with mods that change the logo and the animated fly5.4k downloadsupdated 23 mo ago
- Meta Knight Bossby GuilhermeA new boss arrives, from kirby here's: Meta Knight. watch out for it's speed, could catch you off-guard UPDATE: there's a modpack containing all of my bosses now, check it here: It can be found in The Womb and Utero Includes a champion: Galacta Knight It has it's own music from the original game...5.4k downloadsupdated 2 y ago
- Super Scroto's Boss Resprite Modby 76561198893672165Super Mod that resprites plenty bosses by Scroto's choice at Scroto's style! I didn't make these resprites, all credit goes by my lad Scroto McBolas. Ton of effort was put into this so hope you enjoy and feedback is welcome.5.3k downloadsupdated 4 y ago
- NE MARCHE PLUS Le Binding Of Isaac Afterbirth+ French Versionby 76561198053733721Dernière MàJ: 01.01.17: v0.5 Grâce à la grande aide de FireInTheHope ( ), la traduction est quasiment finie! il ne reste plus que les bébés Co-op et le menu à traduire! Bonjour à tous! Je vous présente mon mod appelé Le Binding of Isaac! Je vais commencer par faire une traduction complète du jeu...5.3k downloadsupdated 9 y ago
- Friendly Ball Bossesby corkie6Basically this makes the game recognise bosses and mini bosses as enemies! all effects: you can now CAPTURE BOSSES in the FRIENDLY BALL! Delirium bosses spawned with DELIRIOUS now STAY BETWEEN ROOMS!!! NOTE: you no longer know how much health bosses have as they no longer have health bars. -boss...5.3k downloadsupdated 10 y ago
- Bestia z Wadowicby olafw37Beast jako Bestia z Wadowic. 21:37 NOW ALBINO CERTIFIED ✅5.3k downloadsupdated 4 y ago
- Mom's Bartby HengusMThe boy has consumed everyone. Go. Kill the boy. He is beyond help. Destroy him. Save the world.5.3k downloadsupdated 5 mo ago
- No Auto-Cutscenesby StlkngneUpdate: Mega Satan and The Beast unlocks are now supported! To get your unlocks/achievements/completion marks, make sure you walk into the chest rather than taking the void portal. Check your completion marks on the pause menu, and make your choice. Update: If you have Repentogon, you'll get your...5.3k downloadsupdated 6 mo ago
- Mixed Boss Collection Part 2by GuilhermeThis mod is the second part of the Mixed Boss Collection, does to limitations of how many values a mod can save I had to split it in three mods, CLICK HERE for the part 1 and CLICK HERE for the part 3 it also features it's own menu config to change which bosses do you want. list of bosses include...5.3k downloadsupdated 10 mo ago
- Marx Bossby GuilhermeA new boss appears from kirby, here I show: Marx UPDATE: there's a modpack containing all of my bosses now, check it here: It can be found in The Depths and Necropolis Includes it's soul champion It has it's own music from the original game (you can disable it if you don't want with the Mod Confi...5.3k downloadsupdated 3 y ago
- Стишки Антона Чигураby anora vpn #топчикЗаменяет диалог родителей в Ascent на смешные стишки Антона Чигура антон чугур никого не убивал, он какашки айзека подъедал:isaac: thx SprayCheese for translating the description translation for anyone too lazy to use google translate --------------------------------------------------------- Poem...5.3k downloadsupdated 7 mo ago
- Angry Birds Terrence Over Clogby 76561198952564947This mod changes the boss Clog into Terrence from angry birds.5.2k downloadsupdated 9 mo ago
- Delirium Directionsby ZERBI-XCVIIDescription How many times have you reached The Void (probably with an OP build) and wasted your time killing random bosses while searching for Delirium? This mod solves that problem by adding an indicator that shows the distance and the best direction to reach Delirium. Notes: - the indicator wi...5.2k downloadsupdated 4 y ago
- Delirite's Chamberby PixelPlzA Super Secret encounter has appeared below… This mod adds a unique fight against Delirite, a miniboss that can be found in Super Secret Rooms within the Caves and beyond. This special room variant has a chance to replace a normal Super Secret Room, and can only appear once per run. Placing 2, ra...5.2k downloadsupdated 16 mo ago
- Super Mecha Sonic Super Bossby GuilhermeThis mod add an optional super boss: Mecha Sonic, from the game Sonic & Knuckles and also heavily based on the animation Super Mario Bros Z UPDATE: there's a modpack containing all of my bosses now, check it here: you can find it at Dark Room, The Chest and Corpse 2, after clearing each room you...5.1k downloadsupdated 2 y ago
- Monstro reskinby Duże Ilości Naraz PsówDawid Jasper Monstro Reskin and SFX.5.1k downloadsupdated 4 y ago
- The Beast made a mimicby 76561198982862481this mod is very low quality, i made it in less than 15 minutes. My name is edwin5.1k downloadsupdated 20 mo ago
- Angel But's it's Gabriel from Ultrakillby 76561198354546959Angel Replacer5.0k downloadsupdated 4 y ago
- cuter embryosby 76561199169078226makes embryos cute includes blastocyst & delirium5.0k downloadsupdated 16 mo ago
- Boss Resprite - The Bloatby FerpeA simple resprite of the Bloat based off of its Vs. portrait and one of the Four Souls cards. It does replace his anm2 file but it's just switching some frames around, there are no gameplay changes and you can probably override it and it'll be just fine. It even has its champion and Delirium spri...5.0k downloadsupdated 4 y ago
- Siren singing is now Hog Rider!by Hideo KojimaI saw a post on the tboi subreddit made by u/Uh0hSpaghetti0hs about how similar Siren singing is to Hog Rider's, so I decided to turn it into a mod =D5.0k downloadsupdated 4 y ago
475 bosses mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.

