Mods / Bosses

• YYOUR TAKING TOO LONG (Deltarune/Mom's Shadow)by 76561198411934155Replaces Mom's Shadow with Jackenstein's pumpkin from Deltarune Chapter 4, and changes all associated music and sound effects. Gotta mention Pyzzabox and Vern, who uploaded similar (and much higher quality) mods around the same time as this one, go check them out too! I guess great minds think al...17.3k downloadsupdated 17 mo ago
• LLamb Intro Animation + Visual Fixesby EmfflesAdds an intro animation for the lamb like the one Nicalis did as an animation test17.2k downloadsupdated 7 y ago
• AAtlas Bossby electoonAtlas, the stone giant, has appeared in The Depths! An all new boss, Atlas attacks with the tumor-like grimaces on his back, digging around the room and falling flat on his face. (Atlas does not replace any existing boss, he is part of the boss pool for the Depths and has a 15% chance of appearin...17.0k downloadsupdated 9 y ago
• !!!maggy's toy box animation fixesby katsukeyfixes any broken animations in maggy's toybox, let me know if there are any that i havent fixed yet16.7k downloadsupdated 2 y ago
• AAbortionbirth Pack 2: THE HECKONINGby NarilliaWelcome friends to The Binding of Isaac: Abortionbirth Pack 2: The Heckoning, sequel to a total expansion MOD to defeat all other mods! Each item has been designed from scratch with all the care in the world to offer the ideal experience. This mod tops all other mods, EVEN the original Abortionbi...16.6k downloadsupdated 9 y ago
• RRoaring Knight Bossby GuilhermeThis mod adds a (secret?) boss from Deltarune Chapter 3, the Roaring Knight, it can appear in corpse 1. you may fight it or try the pacifist route... this mod is included in a modpack that contains all of my bosses now, check it here: it includes it's own boss theme. stage api is required to make...16.6k downloadsupdated 9 mo ago
• KKirby over Plumby NyanTigerKirby is here to play! Changes Baby Plum's sprites to make her look like Kirby! Also changes Fruity Plum to look like little Kirby and Plum Flute to resembe Invincible Candy. I couldn't find anything similar to a flute from Kirby games/anime, so Invincible Candy it is. Could've done more with it...16.5k downloadsupdated 4 y ago
• OOG Bestiaby Luv ToniqueFor those who want the original Bestia mod, I made sure to hold onto it just for you! :) No future changes will be made to this mod. This is purely for people who wanted the original look.15.9k downloadsupdated 10 mo ago
• AAbortionbirth (OUTDATED, GET PACK 2)by NarilliaWelcome friends to The Binding of Isaac: Abortionbirth, a total expansion MOD to defeat all other mods! Each item has been designed from scratch with all the care in the world to offer the ideal experience. No refunds. So far, we've done 103 items, but soon enough I guarantee you our following li...15.9k downloadsupdated 9 y ago
• BBoss Portrait Overhaul (yes its another one)by 76561198408359456Its hard to come up with a unique name for a mod that overhauls boss portraits ok I was getting tired of looking at these same old boss portraits that looked kinda lame and also very inaccurate. After waiting for awhile for a good portrait resprite mod to come out I just decided to stop being laz...15.7k downloadsupdated 3 y ago
• [[REP]Expansion Pack:The Glaze Ceremonyby 76561199092966895中文版介绍位于后方。详细说明请查看MOD文件夹下的四个document。 Welcome to my ceremory,friends. Here, you can follow the pace of Qing, a brand new leading role in the basement, to explore the mysteries hidden under deep below. "Bank? It seens so.." "Beneath the floor.. something hidden?" "Qing, can you help me?" "The power...15.6k downloadsupdated 21 mo ago
• AAngry Faic Spawn Indicators [REP+]by PixelPlzReplaces the boring (and smelly) spawn indicator pentagram with the charming and awesome angry faic of Newgrounds fame, similar to the mod they allegedly (definitely) ripped off. (also makes them slightly brighter for visibility)15.5k downloadsupdated 18 mo ago
• TThe Greening of Isaac: Regreen'dby Dracula joeHave you ever wanted to play your favourite crying infant, but coloured green? IF so, then this mod is for you!!! Features Currently, the mod adds 2 characters: Green Isaac and Green Cain, along with 10+ unlockable items you can find in normal pools and 60+ "green" items you can find! It also add...15.5k downloadsupdated 3 y ago
• LLocal PVPby The_Evil_PickleAllows a second player to control the enemies! Tired of local co-op? This mod changes it into local PVP! Instead of helping the main player, the second player is randomly given control of enemies. Player 2's goal is to use the enemies they can control to impede the progress of Player 1, eventuall...15.4k downloadsupdated 10 y ago
• HHoneyVee's Monster Respritesby HoneyVeeThis mod updates several monster sprites and outdated animations that didn't get any love when repentance came out, to make them look on par with the current style! And also several Fiend Folio enemies that branch from said outdated sprites! (Warning, some resprites might conflict with eachother...14.9k downloadsupdated 15 mo ago
• VVs. Mega-Lomeby ♪NotBoogieChanges Mega Satan into Mega Melome; for the short & vaguely-furry monstergirl enjoyers. Changes include fully custom art and animations. Also changes the sprites of Fallen Gabriel and Fallen Uriel into top and bottom heavy shortstacks, respectively. Why? Because funny.14.8k downloadsupdated 17 mo ago
• CCrabby's Cretinsby CrabbyA new enemy MOD is here! Crabby's Cretins MOD is a small scale enemy expansion, featuring... 30+ new enemies to deal moderate damage! 6 vanilla Boss Champions with new attack patterns. Over 5000 rooms! (may be inaccurate) 2 new threats to be encountered in chapter 5... Customization with Dead Sea...14.7k downloadsupdated 13 mo ago
• MMega Satan and Satan Waifu (from Booba Bosses)by 76561198803343195I DID NOT MAKE THIS TEXTURE DISCLAIMER I made this mod because the one who made a similar mod for some reason left the mother’s textures, which I don’t need. If the creator wants this mod to be removed I will do so, since I only wanted to have only mega satan and satan. The sprites come from:14.6k downloadsupdated 22 mo ago
• WWaifu Nunby 76561199223159583With this mod you will love Angelic Deals - DISCLAIMER- This mod was created due to a request. If the creator wants this mod to be removed I will do so.14.1k downloadsupdated 22 mo ago
• HHardMode Major Boss Patterns(AB+ only)by DotThis is AB+ version of the mod, Repentance+ version is here: This mod adds new patterns and phases of major bosses in hard mode. Also involves some pattern enhancements, shields and resprites. This mod is still in development, bosses with new patterns or phases implemented are as follows. -The La...14.1k downloadsupdated 5 mo ago
• CCute Momby eweThis mod changes the sprites of Mom to look more cute rather than terrifying. It affects her default form as well as her champion variants (blue and red) + her Mausoleum / Gehenna variant. It also changes her portrait during the VS screen and the pop-up from Mom's Bra. This mod will override or w...14.1k downloadsupdated 21 mo ago
• CCinemaSatanby 76561199185343587This mod makes Satan's sprite the CINEMA guy14.0k downloadsupdated 16 mo ago
• GGaster over Satanby 76561199060727605HI this is a mod I made for THIS DELTARUNE VIDEO: It appears as b-roll for barely any time. I thought it'd be funny but like. Nobody's acknowledged it yet. ENJOY THE FRUITS OF MY LABOR OR BEGONE!!!!! This ONLY replaces base Satan and his respective boss portrait...might make more, but don't count...14.0k downloadsupdated 4 mo ago
• IIsaac is susby 76561199080435951OH MY F*CKING GOD, ISAAC IS SUS THE FINAL UPDATE IS HERE BOY The mod adds a new character and his the taintend version, also add a new item and replace some textures and music (Ghost Mother is Jerma sus, Dogma is sus and we are living in the light but is STOP POSTING ABOUT AMONG US) theres also a...13.9k downloadsupdated 5 y ago
• TThe Beast Replaced by Evil Fucking Catby 76561198995154797This vile beast has taken over the underworld! Stop her before she unleashes chaos on the basement! This mod replaces the beast with my cat (Tess) Made as a joke for some friends of mine13.9k downloadsupdated 2 y ago
• AASSversaryby Demi-BluntFeel free to point and laugh at anybody who: -Thinks this is a horny mod. -Uses this as a horny mod. Inspired by the Ass of infamy mod, here's the ASSversary. Another cursed mod that buffs The Adversary. I am totally going to hell for this13.9k downloadsupdated 5 y ago
• HHMBP MOD Entity n API Packby DotThis MOD is a entities collection to be used in HMBP MODs. If this MOD is not enabled, major bosses will not use some patterns or enter to a new phase.13.8k downloadsupdated 5 y ago
• FFLESH PRISON over Moms Heartby 76561198420588728I thought it'd be funny ok. The mod changes the looks and sounds of It lives, as well as Mom's Heart fights. It will probably conflict with other reskins so be aware of that. Credits: FLESH PRISON as well as the music from ULTRAKILL by Arsi 'Hakita' Patala. p.s. Its my first ever mod for isaac so...13.5k downloadsupdated 19 mo ago
• SSiren XLby ShweetGives the Siren boss in Mausoleum some much needed architectural support. If you notice some issues with the project design, please let me know. I'd also recommend checking out this mod, too: Licensed under Creative Commons Zero. Feel free to do whatever with this mod, with or without permission.13.5k downloadsupdated 10 mo ago
• [[RGON]Benighted Soulby 76561198366643385!!!ATTENTION!!! REP+ is unrecommended, it may cause unknown issues REPENTOGON is necessary - What's in it? · 11+1 characters with complete unlock-trees! · 200+ items! · 3 transformations! · 6+1 bosses! · 11 challenges! · 2 curses! · More rooms! · More poops! · More bugs! - What's in the future? ·...13.4k downloadsupdated 17 d ago
• BBooba Neko Hushy Reborn !!REUPLOAD!!by 76561199438704623REUPLOADED MOD!!! By me, Dosecat Credits to the Original Creator: Maggotz (PixelKat) SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SUBSCRIBE SU...13.4k downloadsupdated 20 mo ago
• KKawaii Pin 2.0 and Needleby rocketThe Repentance Version of Kawaii Pin! Now with a Needle Redesign! Suggestions in comments.13.3k downloadsupdated 6 y ago
• SShrek Monstro Mod v2by NeoDementThis mod replaces Monstro with Shrek! He has some unique attacks and can even sometimes drop a new trinket*! *trinket drops 50% of the time if you haven't already seen it this run UPDATE 25/08/2021 Main changes: -Fixed console spam. -Lots of code cleanup/improvements. -Moved some variables to the...13.3k downloadsupdated 5 y ago
• BBiblically Accurate Angelsby FrankenThis mod change the sprite of Uriel and Gabriel to look like angels from religious books like the bible or revelation! The fallen angels also have their own unique resprite! I will keep updating and polishing the sprites so let me know any issues or ideas you have The origin of this mod starts wi...13.3k downloadsupdated 3 y ago
• SSplashy and Roghornby Goganidze13.1k downloadsupdated 5 y ago
• DDogma is Heinz Doofenshmirtzby 76561199212957909MY NAME IS DOOF AND YOU'LL DO WHAT I SAY WOOP WOOP MY NAME IS DOOF AND YOU'LL DO WHAT I SAY WOOP WOOP MY NAME IS DOOF AND YOU'LL DO WHAT I SAY WOOP WOOP MY NAME IS DOOF AND YOU'LL DO WHAT I SAY WOOP WOOP MY NAME IS DOOF AND YOU'LL DO WHAT I SAY WOOP WOOP MY NAME IS DOOF AND YOU'LL DO WHAT I SAY W...13.1k downloadsupdated 3 mo ago
• DDelirium (ugly) Troll faceby 󠀡󠀡󠀡󠀡 󠀡󠀡󠀡This very good mod turns Delirium into very funny troll. Looks bad, beacuse im stupid.13.0k downloadsupdated 5 y ago
• TThe Cathedral in Greed Modeby 76561199034036813It's finally here! The much awaited squeal to Planetariums in Greed Mode, The Cathedral in Greed Mode! So, without further ado, let's get into it! How to get there Getting there is rather simple. Either type "stage 5a" in the debug console (if you want to be a cheater) or go to the end of the wom...12.9k downloadsupdated 3 y ago
• FFem Lambby 76561198376474316This mod simply adds a female version of the Lamb.12.8k downloadsupdated 6 y ago
• [[AB+] [REP] Squash for Daddy longlegsby 76561199192861745Changes "Daddy longlegs" collectible sprite to squash from PvZ, also works on the boss with the same name12.7k downloadsupdated 12 mo ago
• UUltra horsemen mgtextureby EpicAnimationNippleAre you tired of playing the binding of isaac without cool monster girls??? if the answer to that question is yes then you should download this mod this replaces the ultra horsemen textures with awesome monster ladies based on the mgtexture mod by Kerubii the reason i made this was because i real...12.6k downloadsupdated 4 y ago
• GGabriel angels modby 76561199434275811BEHOLD! THE POWER OF AN ANGEL! From the creator of flushed tears, I present to you - Gabriel Angels mod! This mod changes bosses angels into Mr Gabriel Ultrakill from the hit game DOOM Eternal Ultrakill. But not just changes textures, but even adds custom themes for them and angel room, lines fro...12.5k downloadsupdated 2 y ago
• RReverie Bossesby CuerzorThis mod is a submod of Reverie - Touhou Combinations( which is a fan mod for Touhou Project. This mod only includes 7 alt-floor bosses, and 2 collectibles for 2 secret bosses from the original mod. WARNING: DO NOT OPEN BOTH OF THE ORIGINAL MOD AND THIS MOD!!! All included bosses: The Abandoned (...12.2k downloadsupdated 4 y ago
• MMeeps' Monster Respritesby 76561199000831540Meeps' Monster Resprites is a resprite mod (Duh) that aims to overhaul the game's enemies to the much higher quality repentance style, while simultaneously overhauling the game's more bland enemy designs to add a bit more spice and flair. Additionally, a bunch of enemy animations have been change...12.2k downloadsupdated 3 mo ago
• Mmonstro but it's my dog kennyby 76561198901244293say hi to kenny <312.1k downloadsupdated 21 mo ago
• HHp Bar For Enemies (REWORK)by PxntxrezThis is a rework of original HP Bars For Enemies mod by Pxntxrez and JaRo7126 with bug fixes and even more functionality! FEATURES This mod tries to enchance the old Spider Mod hp bar and add something new. This includes: -Added Settings -Showing names of every enemy in the game -2 new types of H...12.1k downloadsupdated 20 mo ago
• BBoss Resprite - Isaac + Blue Babyby FerpeResprited and reanimated these two to make them look closer to their playable counterparts (blue bapy my beloved) Complete with their Delirium versions! It's extremely likely this mod won't be compatible with other mods that also change this boss!11.9k downloadsupdated 4 y ago
• UUpdated Boss Rushby kittenchillyCompatible with both Afterbirth+ and Repentance! Did you know the bosses which could appear in the boss rush haven't been updated since Afterbirth? This fixes that, adding the missing bosses from Afterbirth+ and Repentance so that they can finally appear in boss rush! Bosses Added Afterbirth+: Ra...11.9k downloadsupdated 5 y ago

475 bosses mods, most downloaded first. Each one has its own page here with what it needs to run and where its author publishes it; the files themselves stay with the author and are never re-hosted on this site.